Applying Transcranial Magnetic Stimulation (TMS) Over the Dorsal Visual Pathway Induces Schizophrenia-like Disruption of Perceptual Closure.

Abstract:

:Perceptual closure ability is postulated to depend upon rapid transmission of magnocellular information to prefrontal cortex via the dorsal stream. In contrast, illusory contour processing requires only local interactions within primary and ventral stream visual regions, such as lateral occipital complex. Schizophrenia is associated with deficits in perceptual closure versus illusory contours processing that is hypothesized to reflect impaired magnocellular/dorsal stream. Perceptual closure and illusory contours performance was evaluated in separate groups of 12 healthy volunteers during no TMS, and during repetitive 10 Hz rTMS stimulation over dorsal stream or vertex (TMS-vertex). Perceptual closure and illusory contours were performed in 11 schizophrenia patients, no TMS was applied in these patients. TMS effects were evaluated with repeated measures ANOVA across treatments. rTMS significantly increased perceptual closure identification thresholds, with significant difference between TMS-dorsal stream and no TMS. TMS-dorsal stream also significantly reduced perceptual closure but not illusory contours accuracy. Schizophrenia patients showed increased perceptual closure identification thresholds relative to controls in the no TMS condition, but similar to controls in the TMS-dorsal stream condition. Conclusions of this study are that magnocellular/dorsal stream input is critical for perceptual closure but not illusory contours performance, supporting both trickledown theories of normal perceptual closure function, and magnocellular/dorsal stream theories of visual dysfunction in schizophrenia.

journal_name

Brain Topogr

journal_title

Brain topography

authors

Amiaz R,Vainiger D,Gershon AA,Weiser M,Lavidor M,Javitt DC

doi

10.1007/s10548-016-0487-1

subject

Has Abstract

pub_date

2016-07-01 00:00:00

pages

552-60

issue

4

eissn

0896-0267

issn

1573-6792

pii

10.1007/s10548-016-0487-1

journal_volume

29

pub_type

杂志文章
  • Behavioral and Health Correlates of Resting-State Metastability in the Human Connectome Project.

    abstract::Metastability is currently considered a fundamental property of the functional configuration of brain networks. The present study sought to generate a normative reference framework for the metastability of the major resting-state networks (RSNs) (resting-state metastability dataset) and discover their association with...

    journal_title:Brain topography

    pub_type: 杂志文章

    doi:10.1007/s10548-018-0672-5

    authors: Lee WH,Moser DA,Ing A,Doucet GE,Frangou S

    更新日期:2019-01-01 00:00:00

  • Regional magnetic resonance imaging measures for multivariate analysis in Alzheimer's disease and mild cognitive impairment.

    abstract::Automated structural magnetic resonance imaging (MRI) processing pipelines are gaining popularity for Alzheimer's disease (AD) research. They generate regional volumes, cortical thickness measures and other measures, which can be used as input for multivariate analysis. It is not clear which combination of measures an...

    journal_title:Brain topography

    pub_type: 杂志文章

    doi:10.1007/s10548-012-0246-x

    authors: Westman E,Aguilar C,Muehlboeck JS,Simmons A

    更新日期:2013-01-01 00:00:00

  • P300 and neuropsychological tests as measures of aging: scalp topography and cognitive changes.

    abstract::The rationale for the present study was to investigate several aspects of P300 topography in relation to aging and neuropsychological measures. We administered an auditory oddball ERP task to 72 participants aged 21.8 to 94.7 years, 36 males and 36 females, in addition to the Wechsler Abbreviated Scales of Intelligenc...

    journal_title:Brain topography

    pub_type: 杂志文章

    doi:10.1023/a:1012563605837

    authors: Fjell AM,Walhovd KB

    更新日期:2001-10-01 00:00:00

  • Characterisation and reduction of the EEG artefact caused by the helium cooling pump in the MR environment: validation in epilepsy patient data.

    abstract::The EEG acquired simultaneously with fMRI is distorted by a number of artefacts related to the presence of strong magnetic fields, which must be reduced in order to allow for a useful interpretation and quantification of the EEG data. For the two most prominent artefacts, associated with magnetic field gradient switch...

    journal_title:Brain topography

    pub_type: 杂志文章

    doi:10.1007/s10548-014-0408-0

    authors: Rothlübbers S,Relvas V,Leal A,Murta T,Lemieux L,Figueiredo P

    更新日期:2015-03-01 00:00:00

  • Meditators and non-meditators: EEG source imaging during resting.

    abstract::Many meditation exercises aim at increased awareness of ongoing experiences through sustained attention and at detachment, i.e., non-engaging observation of these ongoing experiences by the intent not to analyze, judge or expect anything. Long-term meditation practice is believed to generalize the ability of increased...

    journal_title:Brain topography

    pub_type: 杂志文章

    doi:10.1007/s10548-009-0107-4

    authors: Tei S,Faber PL,Lehmann D,Tsujiuchi T,Kumano H,Pascual-Marqui RD,Gianotti LR,Kochi K

    更新日期:2009-11-01 00:00:00

  • Brain and human pain: topographic EEG amplitude and coherence mapping.

    abstract::Nineteen young healthy volunteers (8 males and 11 females) participated in an experimental ice-cube cold pressor test to study topographic changes of EEG parameters in response to painful stimulation. EEG was recorded with 19 electrodes and quantified by amplitude and coherence analyses. Mean amplitudes and values for...

    journal_title:Brain topography

    pub_type: 杂志文章

    doi:10.1007/BF01186771

    authors: Chen AC,Rappelsberger P

    更新日期:1994-01-01 00:00:00

  • A Comparison of Evoked and Non-evoked Functional Networks.

    abstract::The growing interest in brain networks to study the brain's function in cognition and diseases has produced an increase in methods to extract these networks. Typically, each method yields a different network. Therefore, one may ask what the resulting networks represent. To address this issue we consider electrocortico...

    journal_title:Brain topography

    pub_type: 杂志文章

    doi:10.1007/s10548-018-0692-1

    authors: Hebbink J,van Blooijs D,Huiskamp G,Leijten FSS,van Gils SA,Meijer HGE

    更新日期:2019-05-01 00:00:00

  • Grey Matter Volumes in the Executive Attention System Predict Individual Differences in Effortful Control in Young Adults.

    abstract::Effortful control (EC), considered as one component of temperament, describes an individual's capacity for self-regulation. Previous neuroimaging studies have provided convergent evidence that individual differences in EC are determined by the functioning of neural systems subserving executive attention, primarily com...

    journal_title:Brain topography

    pub_type: 杂志文章

    doi:10.1007/s10548-018-0676-1

    authors: Wei L,Guo N,Baeken C,Bi M,Wang X,Qiu J,Wu GR

    更新日期:2019-01-01 00:00:00

  • The "Mozart effect": an electroencephalographic analysis employing the methods of induced event-related desynchronization/synchronization and event-related coherence.

    abstract::The event-related responses of 18 individuals were recorded while they were listening to 3 music clips of 6 s duration which were repeated 30 times each. The music clips differed in the level of their complex structure, induced mood, musical tempo and prominent frequency. They were taken from Mozart's sonata (K. 448),...

    journal_title:Brain topography

    pub_type: 杂志文章

    doi:10.1023/b:brat.0000006331.10425.4b

    authors: Jausovec N,Habe K

    更新日期:2003-01-01 00:00:00

  • Permutation Mutual Information: A Novel Approach for Measuring Neuronal Phase-Amplitude Coupling.

    abstract::Cross-frequency phase-amplitude coupling (PAC) in neuronal oscillations network plays an important functional role in large scale neuronal communication and neuronal encoding. In the present study, a novel approach named permutation mutual information (PMI) was applied in measuring PAC. It is derived from the permutat...

    journal_title:Brain topography

    pub_type: 杂志文章

    doi:10.1007/s10548-017-0599-2

    authors: Cheng N,Li Q,Wang S,Wang R,Zhang T

    更新日期:2018-03-01 00:00:00

  • Computerized electroencephalography in the evaluation of early dementia.

    abstract::In elderly patients presenting to an ambulatory practice with complaints of cognitive disturbance, early dementia must be differentiated from depression. The present paper describes the application of standard electroencephalography and evoked potential testing (EEG/EP) and computerized electroencephalography with evo...

    journal_title:Brain topography

    pub_type: 杂志文章

    doi:10.1007/BF01129605

    authors: Jordan SE,Nowacki R,Nuwer M

    更新日期:1989-07-01 00:00:00

  • Increased gamma oscillations evoked by physically salient distracters are associated with schizotypy.

    abstract::Over the last decade, there has been growing interest in aberrant salience as a precursor of positive symptoms in schizophrenia. The present study investigates the neurophysiology of attentional capture by salient stimuli in the visual modality. Evoked oscillatory activity in the gamma frequency range (40 Hz) was asse...

    journal_title:Brain topography

    pub_type: 杂志文章

    doi:10.1007/s10548-014-0418-y

    authors: Kornmayer L,Leicht G,Mulert C

    更新日期:2015-01-01 00:00:00

  • The value of EEG-mapping in focal cerebral lesions.

    abstract::In 148 patients with focal cerebral lesions the findings of EEG mapping, routine EEG and CT were compared. Regarding etiology 43 patients suffered from completed stroke (CS), 43 patients from transient ischemic attack (TIA), 33 patients had an intracerebral hemorrhage (ICH) and 29 an hemispheric tumor. In 37 patients ...

    journal_title:Brain topography

    pub_type: 杂志文章

    doi:10.1007/BF01129003

    authors: Logar C,Boswell M

    更新日期:1991-07-01 00:00:00

  • Electrocortical Dynamics in Children with a Language-Learning Impairment Before and After Audiovisual Training.

    abstract::Detecting and discriminating subtle and rapid sound changes in the speech environment is a fundamental prerequisite of language processing, and deficits in this ability have frequently been observed in individuals with language-learning impairments (LLI). One approach to studying associations between dysfunctional aud...

    journal_title:Brain topography

    pub_type: 杂志文章

    doi:10.1007/s10548-015-0466-y

    authors: Heim S,Choudhury N,Benasich AA

    更新日期:2016-05-01 00:00:00

  • High and low stimulus-driven conflict engage segregated brain networks, not quantitatively different resources.

    abstract::Task-irrelevant information is constantly present in our environment and may interfere with the processing of the information necessary to achieve goal-directed behavior. While task goals determine which information must be suppressed, the demand for inhibitory control depends on the strength of the interference induc...

    journal_title:Brain topography

    pub_type: 杂志文章

    doi:10.1007/s10548-013-0303-0

    authors: Chouiter L,Dieguez S,Annoni JM,Spierer L

    更新日期:2014-03-01 00:00:00

  • The effect of slice orientation on auditory FMRI at the level of the brainstem.

    abstract::Although auditory information is processed in several subcortical nuclei, most fMRI studies focus solely on the auditory cortex and do not take brainstem responses into account. One common difficulty in obtaining clear functional brainstem recordings is due to heartbeat related motion, manifested in the rostro-caudal ...

    journal_title:Brain topography

    pub_type: 杂志文章

    doi:10.1007/s10548-010-0141-2

    authors: Slabu LM

    更新日期:2010-09-01 00:00:00

  • Optimal electrode placements for adequate spatial sampling of auditory evoked potentials.

    abstract::When evoked responses are used in clinical practice and research the measures that are most commonly considered are the latencies and amplitudes of EP components as measured at a single electrode site. Our recent studies have shown that multichannel recordings yield measures such as potential field asymmetry that may ...

    journal_title:Brain topography

    pub_type: 杂志文章

    doi:10.1007/BF01187713

    authors: Sidman RD,Ford MR,Ramsey G

    更新日期:1994-04-01 00:00:00

  • Methodology for combined TMS and EEG.

    abstract::The combination of transcranial magnetic stimulation (TMS) with simultaneous electroencephalography (EEG) provides us the possibility to non-invasively probe the brain's excitability, time-resolved connectivity and instantaneous state. Early attempts to combine TMS and EEG suffered from the huge electromagnetic artifa...

    journal_title:Brain topography

    pub_type: 杂志文章

    doi:10.1007/s10548-009-0123-4

    authors: Ilmoniemi RJ,Kicić D

    更新日期:2010-01-01 00:00:00

  • Comparing electrophysiological correlates of word production in immediate and delayed naming through the analysis of word age of acquisition effects.

    abstract::Most EEG studies analysing speech production with event related brain potential (ERP) have adopted silent metalinguistic tasks or delayed or tacit picture naming in order to avoid possible artefacts during motor preparation. A central issue in the interpretation of these results is whether the processes involved in th...

    journal_title:Brain topography

    pub_type: 杂志文章

    doi:10.1007/s10548-010-0162-x

    authors: Laganaro M,Perret C

    更新日期:2011-03-01 00:00:00

  • Source generators of mismatch negativity to multiple deviant stimulus types.

    abstract::The purpose of the present study was to investigate auditory stimulus feature processing and how neural generators might differ among the mismatch negativity (MMN) responses to intensity, frequency, and duration deviant stimuli. Data collected from 72 electrodes in twelve adult female subjects were analyzed. For each ...

    journal_title:Brain topography

    pub_type: 杂志文章

    doi:10.1023/a:1012992829580

    authors: Schairer KS,Gould HJ,Pousson MA

    更新日期:2001-01-01 00:00:00

  • Towards Using Microstate-Neurofeedback for the Treatment of Psychotic Symptoms in Schizophrenia. A Feasibility Study in Healthy Participants.

    abstract::Spontaneous EEG signal can be parsed into sub-second periods of stable functional states (microstates) that assumingly correspond to brief large scale synchronization events. In schizophrenia, a specific class of microstate (class "D") has been found to be shorter than in healthy controls and to be correlated with pos...

    journal_title:Brain topography

    pub_type: 杂志文章

    doi:10.1007/s10548-015-0460-4

    authors: Diaz Hernandez L,Rieger K,Baenninger A,Brandeis D,Koenig T

    更新日期:2016-03-01 00:00:00

  • Altered directed connectivity in patients with early vascular dementia during a visual oddball task.

    abstract::The altered functional connectivity in the brain of patients with early vascular dementia (VaD) is poorly understood. Here we investigated the directed connectivity differences between VaD and normal elderly while performing a visual oddball task. Multichannel EEG data during a visual oddball task were recorded for 12...

    journal_title:Brain topography

    pub_type: 杂志文章

    doi:10.1007/s10548-014-0385-3

    authors: Xu J,Lou W,Zhao S,Wang C

    更新日期:2015-03-01 00:00:00

  • Reaction Time in a Visual 4-Choice Reaction Time Task: ERP Effects of Motor Preparation and Hemispheric Involvement.

    abstract::Reaction time (RT), the most common measure of CNS efficiency, shows intra- and inter-individual variability. This may be accounted for by hemispheric specialization, individual neuroanatomy, and transient functional fluctuations between trials. To explore RT on these three levels, ERPs were measured in a visual 4-cho...

    journal_title:Brain topography

    pub_type: 杂志文章

    doi:10.1007/s10548-016-0473-7

    authors: Antonova I,van Swam C,Hubl D,Dierks T,Griskova-Bulanova I,Koenig T

    更新日期:2016-07-01 00:00:00

  • Did You Listen to the Beat? Auditory Steady-State Responses in the Human Electroencephalogram at 4 and 7 Hz Modulation Rates Reflect Selective Attention.

    abstract::The acoustic envelope of human speech correlates with the syllabic rate (4-8 Hz) and carries important information for intelligibility, which is typically compromised in multi-talker, noisy environments. In order to better understand the dynamics of selective auditory attention to low frequency modulated sound sources...

    journal_title:Brain topography

    pub_type: 杂志文章

    doi:10.1007/s10548-018-0637-8

    authors: Jaeger M,Bleichner MG,Bauer AR,Mirkovic B,Debener S

    更新日期:2018-09-01 00:00:00

  • Discrimination of Tourette Syndrome Based on the Spatial Patterns of the Resting-State EEG Network.

    abstract::Tourette syndrome (TS) is a neuropsychiatric disorder with childhood onset characterized by chronic motor and vocal tics; however, the current diagnosis of TS patients is subjective, as it is mainly assessed based on the parents' description alongside specific evaluations. The early and accurate diagnosis of TS based ...

    journal_title:Brain topography

    pub_type: 杂志文章

    doi:10.1007/s10548-020-00801-5

    authors: Duan K,Wu Q,Liao Y,Si Y,Bore JC,Li F,Tao Q,Lin L,Lei W,Hu X,Yao D,Pei C,Zhang T,Huang L,Xu P

    更新日期:2021-01-01 00:00:00

  • Head motion parameters in fMRI differ between patients with mild cognitive impairment and Alzheimer disease versus elderly control subjects.

    abstract::Motion artifacts are a well-known and frequent limitation during neuroimaging workup of cognitive decline. While head motion typically deteriorates image quality, we test the hypothesis that head motion differs systematically between healthy controls (HC), amnestic mild cognitive impairment (aMCI) and Alzheimer diseas...

    journal_title:Brain topography

    pub_type: 杂志文章

    doi:10.1007/s10548-014-0358-6

    authors: Haller S,Monsch AU,Richiardi J,Barkhof F,Kressig RW,Radue EW

    更新日期:2014-11-01 00:00:00

  • Electrophysiological explorations of the cause and effect of inhibition of return in a cue-target paradigm.

    abstract::Facilitation and inhibition of return (IOR) are, respectively, faster and slower responses to a peripherally cued target. In a spatially uninformative peripheral cueing task, facilitation is normally observed when the interval between the cue and target stimulus, the stimulus onset asynchrony (SOA), is shorter than 25...

    journal_title:Brain topography

    pub_type: 杂志文章

    doi:10.1007/s10548-011-0172-3

    authors: Tian Y,Klein RM,Satel J,Xu P,Yao D

    更新日期:2011-06-01 00:00:00

  • Reliability of Visual and Somatosensory Feedback in Skilled Movement: The Role of the Cerebellum.

    abstract::The integration of vision and somatosensation is required to allow for accurate motor behavior. While both sensory systems contribute to an understanding of the state of the body through continuous updating and estimation, how the brain processes unreliable sensory information remains to be fully understood in the con...

    journal_title:Brain topography

    pub_type: 杂志文章

    doi:10.1007/s10548-015-0446-2

    authors: Mizelle JC,Oparah A,Wheaton LA

    更新日期:2016-01-01 00:00:00

  • P3a from visual stimuli: typicality, task, and topography.

    abstract::A visual three-stimulus (target, nontarget, standard) paradigm was employed in which subjects responded only to the target. Nontarget stimulus properties were varied systematically to evaluate how stimulus typicality (non-novel vs. novel) across task discrimination (easy vs. difficult) conditions affects P3a scalp top...

    journal_title:Brain topography

    pub_type: 杂志文章

    doi:10.1023/a:1022637732495

    authors: Polich J,Comerchero MD

    更新日期:2003-04-01 00:00:00

  • A Finite-Difference Solution for the EEG Forward Problem in Inhomogeneous Anisotropic Media.

    abstract::Accurate source localization of electroencephalographic (EEG) signals requires detailed information about the geometry and physical properties of head tissues. Indeed, these strongly influence the propagation of neural activity from the brain to the sensors. Finite difference methods (FDMs) are head modelling approach...

    journal_title:Brain topography

    pub_type: 杂志文章

    doi:10.1007/s10548-018-0683-2

    authors: Cuartas Morales E,Acosta-Medina CD,Castellanos-Dominguez G,Mantini D

    更新日期:2019-03-01 00:00:00