Abstract:
:Reaction time (RT), the most common measure of CNS efficiency, shows intra- and inter-individual variability. This may be accounted for by hemispheric specialization, individual neuroanatomy, and transient functional fluctuations between trials. To explore RT on these three levels, ERPs were measured in a visual 4-choice RT task with lateralized stimuli (left lateral, left middle, right middle, and right lateral) in 28 healthy right-handed subjects. We analyzed behavioral data, ERP microstates (MS), N1 and P3 components, and trial-by-trial variance. Across subjects, the N1 component was contralateral to the stimulation side. N1-MSs were stronger over the left hemisphere, and middle stimulation evoked stronger activation than lateral stimulation in both hemispheres. The P3 was larger for the right visual field stimulation. RTs were shorter for the right visual hemifield stimulation/right hand responses. Within subjects, covariance analysis of single trial ERPs with RTs showed consistent lateralized predictors of RT over the motor cortex (MC) in the 112-248 ms interval. Decreased RTs were related to negativity over the MC contralateral to the stimulation side, an effect that could be interpreted as the lateralized readiness potential (LRP), and which was strongest for right side stimulation. The covariance analysis linking individual mean RTs and individual mean ERPs showed a frontal negativity and an occipital positivity correlating with decreased RTs in the 212-232 ms interval. We concluded that a particular RT is a composite measure that depends on the appropriateness of the motor preparation to a particular response and on stimulus lateralization that selectively involves a particular hemisphere.
journal_name
Brain Topogrjournal_title
Brain topographyauthors
Antonova I,van Swam C,Hubl D,Dierks T,Griskova-Bulanova I,Koenig Tdoi
10.1007/s10548-016-0473-7subject
Has Abstractpub_date
2016-07-01 00:00:00pages
491-505issue
4eissn
0896-0267issn
1573-6792pii
10.1007/s10548-016-0473-7journal_volume
29pub_type
杂志文章相关文献
BRAIN TOPOGRAPHY文献大全abstract::A large portion of the visual cortex is organized retinotopically, but perception is usually non-retinotopic. For example, a reflector on the spoke of a bicycle wheel appears to move on a circular or prolate cycloidal orbit as the bicycle moves forward, while in fact it traces out a curtate cycloidal trajectory. The m...
journal_title:Brain topography
pub_type: 杂志文章
doi:10.1007/s10548-015-0458-y
更新日期:2016-03-01 00:00:00
abstract::Event-Related Desynchronization (ERD) and Synchronization (ERS) were studied in 20 normal subjects during a Sternberg-type auditory memory-scanning paradigm. Half of the subjects performed the experiment with vowels and the other half with tones as stimuli. The stimuli consisted of 100 msec long synthesized vowels and...
journal_title:Brain topography
pub_type: 杂志文章
doi:10.1007/BF01187669
更新日期:1995-10-01 00:00:00
abstract::Emotionally arousing events can distort our sense of time. We used mixed block/event-related fMRI design to establish the neural basis for this effect. Nineteen participants were asked to judge whether angry, happy and neutral facial expressions that varied in duration (from 400 to 1,600 ms) were closer in duration to...
journal_title:Brain topography
pub_type: 杂志文章
doi:10.1007/s10548-013-0350-6
更新日期:2015-01-01 00:00:00
abstract::While several studies have investigated interactions between the electroencephalography (EEG) and functional magnetic resonance imaging BOLD signal fluctuations, less is known about the associations between EEG oscillations and baseline brain haemodynamics, and few studies have examined the link between EEG power outs...
journal_title:Brain topography
pub_type: 杂志文章
doi:10.1007/s10548-012-0265-7
更新日期:2013-07-01 00:00:00
abstract::Motion artifacts are a well-known and frequent limitation during neuroimaging workup of cognitive decline. While head motion typically deteriorates image quality, we test the hypothesis that head motion differs systematically between healthy controls (HC), amnestic mild cognitive impairment (aMCI) and Alzheimer diseas...
journal_title:Brain topography
pub_type: 杂志文章
doi:10.1007/s10548-014-0358-6
更新日期:2014-11-01 00:00:00
abstract::A new residual function in the inverse problem of equivalent dipole localization methods is proposed which is based on the spatial correlation of the background EEG. This residual has the advantage that it allows the calculation of confidence limits for dipole model parameters. The method was applied to VEP data, and ...
journal_title:Brain topography
pub_type: 杂志文章
doi:10.1007/BF01129050
更新日期:1992-01-01 00:00:00
abstract::Event related potentials (ERPs) to an auditory odd-ball paradigm were recorded with the linked earlobe reference (LER) and with a computer calculated average reference (AR), excluding the two linked earlobe derivations. The study was performed in 30 patients with lesions of frontal, parietal, occipital cortex, unilate...
journal_title:Brain topography
pub_type: 临床试验,杂志文章
doi:10.1007/BF01211176
更新日期:1994-07-01 00:00:00
abstract::The rationale for the present study was to investigate several aspects of P300 topography in relation to aging and neuropsychological measures. We administered an auditory oddball ERP task to 72 participants aged 21.8 to 94.7 years, 36 males and 36 females, in addition to the Wechsler Abbreviated Scales of Intelligenc...
journal_title:Brain topography
pub_type: 杂志文章
doi:10.1023/a:1012563605837
更新日期:2001-10-01 00:00:00
abstract::The high temporal resolution of EEG/MEG data offers a way to improve source reconstruction estimates which provide insight into the spatio-temporal involvement of neuronal sources in the human brain. In this work, we investigated the performance of spatio-temporal regularization (STR) in a current density approach usi...
journal_title:Brain topography
pub_type: 杂志文章
doi:10.1007/s10548-012-0263-9
更新日期:2013-04-01 00:00:00
abstract::States of depression are considered to relate to a cognitive bias reactivity to emotional events. Moreover, gender effect may influence differences in emotional processing. The current study is to investigate whether there is an interaction of cognitive bias by gender on emotional processing in minor depression (MiD) ...
journal_title:Brain topography
pub_type: 杂志文章
doi:10.1007/s10548-015-0444-4
更新日期:2016-03-01 00:00:00
abstract::Electroconvulsive therapy (ECT) has significant short-term antidepressant effects on drug-resistant patients with severe major depression. Animal studies have demonstrated that electroconvulsive seizures produce potentiation-like synaptic remodeling in both sub-cortical and frontal cortical circuits. However, the elec...
journal_title:Brain topography
pub_type: 杂志文章
doi:10.1007/s10548-012-0256-8
更新日期:2013-04-01 00:00:00
abstract::Event-related potentials (ERPs) during a visual oddball paradigm with button-pressing responses were recorded in 12 right-handed subjects from 32 scalp electrodes. The single equivalent current dipole (ECD) of the target C1 (weak occipito-parietal negativity from 30-80 ms) was consistently located at the primary visua...
journal_title:Brain topography
pub_type: 杂志文章
doi:10.1023/a:1023467806268
更新日期:2000-04-01 00:00:00
abstract::We process information from the world through multiple senses, and the brain must decide what information belongs together and what information should be segregated. One challenge in studying such multisensory integration is how to quantify the multisensory interactions, a challenge that is amplified by the host of me...
journal_title:Brain topography
pub_type: 杂志文章,评审
doi:10.1007/s10548-014-0365-7
更新日期:2014-11-01 00:00:00
abstract::The event-related responses of 18 individuals were recorded while they were listening to 3 music clips of 6 s duration which were repeated 30 times each. The music clips differed in the level of their complex structure, induced mood, musical tempo and prominent frequency. They were taken from Mozart's sonata (K. 448),...
journal_title:Brain topography
pub_type: 杂志文章
doi:10.1023/b:brat.0000006331.10425.4b
更新日期:2003-01-01 00:00:00
abstract::Frontal lobe epilepsy has recently been associated with disrupted brain functional connectivity; variations among various resting-state networks (RSNs) across time remains largely unclear. This study applied dynamic functional network connectivity (dFNC) analysis to investigate functional patterns in the temporal and ...
journal_title:Brain topography
pub_type: 杂志文章
doi:10.1007/s10548-018-0678-z
更新日期:2019-05-01 00:00:00
abstract::Action generation relies on a widely distributed network of brain areas. However, little is known about the spatiotemporal dynamics of neuronal activity in the network that gives rise to voluntary action in humans. Here, we used magnetoencephalography (MEG) and source analysis (n = 15, 7 female subjects) to investigat...
journal_title:Brain topography
pub_type: 杂志文章
doi:10.1007/s10548-015-0426-6
更新日期:2016-01-01 00:00:00
abstract::Sensor selection is typically used in magnetoencephalography (MEG) and scalp electroencephalography (EEG) studies, but this practice cannot differentiate between changes in the distribution of neural sources versus changes in the magnitude of neural sources. This problem is further complicated by (1) subject averaging...
journal_title:Brain topography
pub_type: 杂志文章,评审
doi:10.1007/s10548-007-0040-3
更新日期:2008-04-01 00:00:00
abstract::In 148 patients with focal cerebral lesions the findings of EEG mapping, routine EEG and CT were compared. Regarding etiology 43 patients suffered from completed stroke (CS), 43 patients from transient ischemic attack (TIA), 33 patients had an intracerebral hemorrhage (ICH) and 29 an hemispheric tumor. In 37 patients ...
journal_title:Brain topography
pub_type: 杂志文章
doi:10.1007/BF01129003
更新日期:1991-07-01 00:00:00
abstract::Temporal structure is ubiquitous in sensory signals, and the brain has been shown to robustly represent information about temporal structure in the phase of low frequency neural oscillations. In a related construct, the integration of information across the different senses has been proposed to be at least partly due ...
journal_title:Brain topography
pub_type: 杂志文章
doi:10.1007/s10548-017-0560-4
更新日期:2017-09-01 00:00:00
abstract::A single flash accompanied by two auditory beeps tends to be perceived as two flashes (Shams et al. Nature 408:788, 2000, Cogn Brain Res 14:147-152, 2002). This phenomenon is known as 'sound-induced flash illusion.' Previous neuroimaging studies have shown that this illusion is correlated with modulation of activity i...
journal_title:Brain topography
pub_type: 杂志文章
doi:10.1007/s10548-009-0090-9
更新日期:2009-05-01 00:00:00
abstract::Ten right-handed students were submitted to a protocol of cognitive visual stimulations based on six successive sequences: EC1, EO, B1, B2, B3, EC2. Following a first "eyes closed" (EC1) multiple EEG recording (16 EEG leads, plus polygraphy), and an "eyes-open" recording (EO) with central visual fixation, 60 computer-...
journal_title:Brain topography
pub_type: 杂志文章
doi:10.1007/BF01128857
更新日期:1990-10-01 00:00:00
abstract::Magnetoencephalography provides precise information about the temporal dynamics of brain activation and is an ideal tool for investigating rapid cognitive processing. However, in many cognitive paradigms visual stimuli are used, which evoke strong brain responses (typically 40-100 nAm in V1) that may impede the detect...
journal_title:Brain topography
pub_type: 杂志文章
doi:10.1007/s10548-012-0217-2
更新日期:2012-07-01 00:00:00
abstract::Automated structural magnetic resonance imaging (MRI) processing pipelines are gaining popularity for Alzheimer's disease (AD) research. They generate regional volumes, cortical thickness measures and other measures, which can be used as input for multivariate analysis. It is not clear which combination of measures an...
journal_title:Brain topography
pub_type: 杂志文章
doi:10.1007/s10548-012-0246-x
更新日期:2013-01-01 00:00:00
abstract::The acoustic envelope of human speech correlates with the syllabic rate (4-8 Hz) and carries important information for intelligibility, which is typically compromised in multi-talker, noisy environments. In order to better understand the dynamics of selective auditory attention to low frequency modulated sound sources...
journal_title:Brain topography
pub_type: 杂志文章
doi:10.1007/s10548-018-0637-8
更新日期:2018-09-01 00:00:00
abstract::Neural activity within the human brain produces electrical potentials that are transmitted through the various tissues of the head to the scalp. A three-dimensional finite difference model has been applied to simulate this process and used as the basis for an inverse model, wherein known potentials on the scalp are us...
journal_title:Brain topography
pub_type: 杂志文章
doi:10.1007/s10548-005-6029-x
更新日期:2005-07-01 00:00:00
abstract::In an earlier experiment, we have used the BTi twin MAGNES system (2 x 37 channels) to record the evoked magnetic field from five healthy right-handed male volunteers using two tasks: visual recognition of complex objects including faces and facial expressions of emotion. We have repeated the experiment with one of th...
journal_title:Brain topography
pub_type: 杂志文章
doi:10.1023/a:1022258620435
更新日期:1999-07-01 00:00:00
abstract::Contralateral somatosensory evoked fields (SEF) by whole head MEG after unilateral median and ulnar nerve stimulation of both hands were studied in 10 healthy right-handed subjects. Major parameters describing cortical activity were examined to discriminate median and ulnar nerve evoked responses. Somatic sensitivity ...
journal_title:Brain topography
pub_type: 杂志文章
doi:10.1007/s10548-006-0010-1
更新日期:2006-01-01 00:00:00
abstract::EEG-signals were recorded from subjects as they performed a modified version of Schneider's and Shiffrin's memory search paradigm. The hypothesis was tested whether individual (centre of gravity) alpha frequency, termed IAF, is related to memory performance and/or attentional demands. The results show that memory perf...
journal_title:Brain topography
pub_type: 杂志文章
doi:10.1007/BF01128991
更新日期:1993-04-01 00:00:00
abstract::Recent brain imaging studies suggest that semantic processing of words and images may share a common neural network, although modality-specific activation can also be observed. Other studies using event-related potentials (ERPs) report that brain responses to words and images may already differ at approximately 150 ms...
journal_title:Brain topography
pub_type: 杂志文章
doi:10.1023/a:1014502925003
更新日期:2002-04-01 00:00:00
abstract::It is well known that, following an early visual deprivation, the neural network involved in processing auditory spatial information undergoes a profound reorganization. In particular, several studies have demonstrated an extensive activation of occipital brain areas, usually regarded as essentially "visual", when ear...
journal_title:Brain topography
pub_type: 杂志文章
doi:10.1007/s10548-009-0075-8
更新日期:2009-05-01 00:00:00