Abstract:
:In an earlier experiment, we have used the BTi twin MAGNES system (2 x 37 channels) to record the evoked magnetic field from five healthy right-handed male volunteers using two tasks: visual recognition of complex objects including faces and facial expressions of emotion. We have repeated the experiment with one of the five subjects using the BTi whole head system (148 channels). Magnetic field tomography (MFT) was used to extract 3D estimates of brain activity millisecond by millisecond from the recorded magnetoencephalographic (MEG) signals. Results from the MFT analysis of the average signals of the five subjects have been reported elsewhere (Streit et al. 1997; Streit et al. 1999). In this paper, we present results of the detailed single trial analysis for the subject recorded from the whole head system. We found activations in areas extending from the occipital pole to anterior areas. Regions of interest (ROIs) were defined entirely on functional criteria and confirmed independently by the location of the maximum activity on the MRI. Activation curves for each ROI were computed and objective statistical measures (Kolmogorov-Smirnov test) were then used to identify time segments for which the ROI activity showed significant differences both within the same and across different object/emotion categories. Emphasis is placed on the quantification of the activity from two ROIs, fusiform gyrus (FG) and amygdala (AM), which have been best studied in the context of processing of faces and facial expressions of emotion, respectively. We found no face-specific area as such, but instead areas like the FG was activated by all complex objects at roughly similar latencies and varying strengths. The amygdala activity was significantly different between 150 and 180 ms for fearful expression, and even earlier for happy expression.
journal_name
Brain Topogrjournal_title
Brain topographyauthors
Liu L,Ioannides AA,Streit Mdoi
10.1023/a:1022258620435subject
Has Abstractpub_date
1999-07-01 00:00:00pages
291-303issue
4eissn
0896-0267issn
1573-6792journal_volume
11pub_type
杂志文章相关文献
BRAIN TOPOGRAPHY文献大全abstract::The topography of the visual evoked magnetic response (VEMR) to pattern reversal stimulation was studied in four normal subjects using a single channel BTI magnetometer. VEMRs were recorded from 20 locations over the occipital scalp and the topographic distribution of the most consistent component (P100M) studied. A s...
journal_title:Brain topography
pub_type: 杂志文章
doi:10.1007/BF01129665
更新日期:1991-10-01 00:00:00
abstract::Post-stroke aphasia (PSA), which refers to the loss or impairment of language, is typically caused by left hemisphere lesions. Previous neuroimaging studies have indicated that the pathology of PSA may be related to abnormalities in functional integration. In this study, we used resting-state functional magnetic reson...
journal_title:Brain topography
pub_type: 杂志文章
doi:10.1007/s10548-018-0681-4
更新日期:2019-03-01 00:00:00
abstract::Electrical dipoles oriented perpendicular to the cortical surface are the primary source of the scalp EEGs and MEGs. Thus, in particular, gyri and sulci structures on the cortical surface have a definite possibility to influence the EEGs and MEGs. This was examined by comparing the spatial power spectral density (PSD)...
journal_title:Brain topography
pub_type: 杂志文章
doi:10.1007/s10548-009-0104-7
更新日期:2009-11-01 00:00:00
abstract::Recently studied 'old' stimuli lead to larger frontal and parietal ERP responses than 'new' stimuli. The present experiment investigated the neuromagnetic correlates (MEG) of this 'old-new' effect and its modulation by emotional stimulus content. Highly arousing pleasant, highly arousing unpleasant and un-arousing neu...
journal_title:Brain topography
pub_type: 杂志文章
doi:10.1007/s10548-008-0044-7
更新日期:2008-06-01 00:00:00
abstract::This study examined the effect of modality of stimulation on two measures of cerebral function: (a) the scalp distribution of sensory evoked potentials and (b) the cerebral distribution of radiolabelled HMPAO. Steady-state stimulation in the auditory, somatosensory or visual modality was presented to six subjects. Sca...
journal_title:Brain topography
pub_type: 杂志文章
doi:10.1007/BF01128854
更新日期:1989-10-01 00:00:00
abstract::Accurate source localization of electroencephalographic (EEG) signals requires detailed information about the geometry and physical properties of head tissues. Indeed, these strongly influence the propagation of neural activity from the brain to the sensors. Finite difference methods (FDMs) are head modelling approach...
journal_title:Brain topography
pub_type: 杂志文章
doi:10.1007/s10548-018-0683-2
更新日期:2019-03-01 00:00:00
abstract::Fronto-temporal areas process shared elements of speech and music. Improvisational psychodynamic music therapy (MT) utilizes verbal and musical reflection on emotions and images arising from clinical improvisation. Music listening is shifting frontal alpha asymmetries (FAA) in depression, and increases frontal midline...
journal_title:Brain topography
pub_type: 杂志文章,随机对照试验
doi:10.1007/s10548-012-0254-x
更新日期:2013-04-01 00:00:00
abstract::We process information from the world through multiple senses, and the brain must decide what information belongs together and what information should be segregated. One challenge in studying such multisensory integration is how to quantify the multisensory interactions, a challenge that is amplified by the host of me...
journal_title:Brain topography
pub_type: 杂志文章,评审
doi:10.1007/s10548-014-0365-7
更新日期:2014-11-01 00:00:00
abstract::Intracortical microstimulation and single cell recordings in non-human primates showed that both, muscles and movements are represented in primary motor cortex (M1). This was also suggested in humans using electrophysiological and neuroimaging techniques. Transcranial magnetic stimulation (TMS) thus far was used to st...
journal_title:Brain topography
pub_type: 杂志文章
doi:10.1007/s10548-013-0289-7
更新日期:2014-03-01 00:00:00
abstract::In Autism Spectrum Disorders (ASD), impaired response inhibition and lack of adaptation are hypothesized to underlie core ASD symptoms, such as social communication and repetitive, stereotyped behavior. Thus, the aim of the present study was to compare neural correlates of inhibition, post-error adaptation, and reacti...
journal_title:Brain topography
pub_type: 杂志文章
doi:10.1007/s10548-020-00765-6
更新日期:2020-05-01 00:00:00
abstract::The purpose of the present study was to investigate auditory stimulus feature processing and how neural generators might differ among the mismatch negativity (MMN) responses to intensity, frequency, and duration deviant stimuli. Data collected from 72 electrodes in twelve adult female subjects were analyzed. For each ...
journal_title:Brain topography
pub_type: 杂志文章
doi:10.1023/a:1012992829580
更新日期:2001-01-01 00:00:00
abstract::Effortful control (EC), considered as one component of temperament, describes an individual's capacity for self-regulation. Previous neuroimaging studies have provided convergent evidence that individual differences in EC are determined by the functioning of neural systems subserving executive attention, primarily com...
journal_title:Brain topography
pub_type: 杂志文章
doi:10.1007/s10548-018-0676-1
更新日期:2019-01-01 00:00:00
abstract::In our previous model, we ascertained that the large amplitude waves (LAWs), reported by Barkley and coworkers (1990) in time series magnetoencephalography (MEG) recordings from migraine patients, could be simulated and compared with the recorded signals using a simple plane volume conductor model (Tepley and Wijesing...
journal_title:Brain topography
pub_type: 杂志文章
doi:10.1007/BF01190388
更新日期:1997-04-01 00:00:00
abstract::The combination of frequency-tagging with electroencephalography (EEG) has recently proved fruitful for understanding the perception of beat and meter in musical rhythm, a common behavior shared by humans of all cultures. EEG frequency-tagging allows the objective measurement of input-output transforms to investigate ...
journal_title:Brain topography
pub_type: 杂志文章,评审
doi:10.1007/s10548-017-0605-8
更新日期:2018-03-01 00:00:00
abstract::Magnetoencephalography provides precise information about the temporal dynamics of brain activation and is an ideal tool for investigating rapid cognitive processing. However, in many cognitive paradigms visual stimuli are used, which evoke strong brain responses (typically 40-100 nAm in V1) that may impede the detect...
journal_title:Brain topography
pub_type: 杂志文章
doi:10.1007/s10548-012-0217-2
更新日期:2012-07-01 00:00:00
abstract::Evoked potentials are difficult to analyze because multiple sources are active simultaneously. Principal component analysis and dipole localization are two techniques that have been used to disentangle overlapping sources. Both of these techniques have problems. Principal component analysis suffers from a rotation amb...
journal_title:Brain topography
pub_type: 杂志文章
doi:10.1007/BF01199773
更新日期:1995-01-01 00:00:00
abstract::Despite genetic, morphological and experimental in vivo, data implying fixed abnormalities in patients with absence seizures, attempts to find highly consistent features in the 3-Hz spike-and-wave pattern recorded during sequential seizures from the same subject have been largely unsuccessful. We used a new data decom...
journal_title:Brain topography
pub_type: 杂志文章
doi:10.1023/a:1023462211778
更新日期:1999-01-01 00:00:00
abstract::The high temporal resolution of EEG/MEG data offers a way to improve source reconstruction estimates which provide insight into the spatio-temporal involvement of neuronal sources in the human brain. In this work, we investigated the performance of spatio-temporal regularization (STR) in a current density approach usi...
journal_title:Brain topography
pub_type: 杂志文章
doi:10.1007/s10548-012-0263-9
更新日期:2013-04-01 00:00:00
abstract::Motion artifacts are a well-known and frequent limitation during neuroimaging workup of cognitive decline. While head motion typically deteriorates image quality, we test the hypothesis that head motion differs systematically between healthy controls (HC), amnestic mild cognitive impairment (aMCI) and Alzheimer diseas...
journal_title:Brain topography
pub_type: 杂志文章
doi:10.1007/s10548-014-0358-6
更新日期:2014-11-01 00:00:00
abstract::The growing interest in brain networks to study the brain's function in cognition and diseases has produced an increase in methods to extract these networks. Typically, each method yields a different network. Therefore, one may ask what the resulting networks represent. To address this issue we consider electrocortico...
journal_title:Brain topography
pub_type: 杂志文章
doi:10.1007/s10548-018-0692-1
更新日期:2019-05-01 00:00:00
abstract::Ten right-handed students were submitted to a protocol of cognitive visual stimulations based on six successive sequences: EC1, EO, B1, B2, B3, EC2. Following a first "eyes closed" (EC1) multiple EEG recording (16 EEG leads, plus polygraphy), and an "eyes-open" recording (EO) with central visual fixation, 60 computer-...
journal_title:Brain topography
pub_type: 杂志文章
doi:10.1007/BF01128857
更新日期:1990-10-01 00:00:00
abstract::The event-related responses of 18 individuals were recorded while they were listening to 3 music clips of 6 s duration which were repeated 30 times each. The music clips differed in the level of their complex structure, induced mood, musical tempo and prominent frequency. They were taken from Mozart's sonata (K. 448),...
journal_title:Brain topography
pub_type: 杂志文章
doi:10.1023/b:brat.0000006331.10425.4b
更新日期:2003-01-01 00:00:00
abstract::Brain topography mapping is a useful technique for the representation of electrical activity recorded on the scalp. It clarifies spatial and temporal relationships between different cortical areas. In this work we propose a system which includes several enhancements over those previously proposed, such as an optimised...
journal_title:Brain topography
pub_type: 杂志文章
doi:10.1007/BF01184837
更新日期:1994-10-01 00:00:00
abstract::Most EEG studies analysing speech production with event related brain potential (ERP) have adopted silent metalinguistic tasks or delayed or tacit picture naming in order to avoid possible artefacts during motor preparation. A central issue in the interpretation of these results is whether the processes involved in th...
journal_title:Brain topography
pub_type: 杂志文章
doi:10.1007/s10548-010-0162-x
更新日期:2011-03-01 00:00:00
abstract::The scalp topography of the middle latency auditory evoked potential (MLAEP) Pa component following left and right ear click stimulation was investigated in 15 normal hearing and neurologically intact right-handed subjects. An unbiased reference was employed. The Pa component showed a broad voltage field that was reco...
journal_title:Brain topography
pub_type: 杂志文章
doi:10.1007/BF01129337
更新日期:1988-10-01 00:00:00
abstract::Posterior cortical atrophy (PCA), considered a visual variant of Alzheimer's disease, has similar pathological characteristics yet shows a selective visual manifestation with relative preservation of other cortical areas, at least at early stages of disease. Using a gamut of imaging methods, we aim to evaluate the glo...
journal_title:Brain topography
pub_type: 杂志文章
doi:10.1007/s10548-020-00788-z
更新日期:2020-09-01 00:00:00
abstract::In elderly patients presenting to an ambulatory practice with complaints of cognitive disturbance, early dementia must be differentiated from depression. The present paper describes the application of standard electroencephalography and evoked potential testing (EEG/EP) and computerized electroencephalography with evo...
journal_title:Brain topography
pub_type: 杂志文章
doi:10.1007/BF01129605
更新日期:1989-07-01 00:00:00
abstract::The attentional blink (AB) is a transient attentional deficit that occurs when two stimuli that must both be detected are presented within an interval of less than 500 ms. Event-related potential (ERP) investigations have suggested that the AB affects a specific component, the P3, which is suppressed when targets are ...
journal_title:Brain topography
pub_type: 杂志文章
doi:10.1007/s10548-011-0199-5
更新日期:2012-04-01 00:00:00
abstract::Although impairments related to somatosensory perception are common in schizophrenia, they have rarely been examined in functional imaging studies. In the present study, magnetoencephalography (MEG) was used to identify neural networks that support attention to somatosensory stimuli in healthy adults and abnormalities...
journal_title:Brain topography
pub_type: 杂志文章
doi:10.1007/s10548-009-0122-5
更新日期:2010-03-01 00:00:00
abstract::The combination of transcranial magnetic stimulation (TMS) with simultaneous electroencephalography (EEG) provides us the possibility to non-invasively probe the brain's excitability, time-resolved connectivity and instantaneous state. Early attempts to combine TMS and EEG suffered from the huge electromagnetic artifa...
journal_title:Brain topography
pub_type: 杂志文章
doi:10.1007/s10548-009-0123-4
更新日期:2010-01-01 00:00:00