The usefulness of the Laplacian in principal component analysis and dipole source localization.

Abstract:

:Evoked potentials are difficult to analyze because multiple sources are active simultaneously. Principal component analysis and dipole localization are two techniques that have been used to disentangle overlapping sources. Both of these techniques have problems. Principal component analysis suffers from a rotation ambiguity. Dipole localization suffers from biases when the model used to derive the sources from the scalp potentials is misspecified. Using computer simulations we demonstrate that by applying both of these techniques to the Laplacian of the voltages rather than to the raw voltages the problems associated with the two techniques are reduced. Computer programs for the analyses are presented in an Appendix.

journal_name

Brain Topogr

journal_title

Brain topography

authors

Klein SA,Carney T

doi

10.1007/BF01199773

subject

Has Abstract

pub_date

1995-01-01 00:00:00

pages

91-108

issue

2

eissn

0896-0267

issn

1573-6792

journal_volume

8

pub_type

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