Brain mapping analysis in patients with hepatic encephalopathy.

Abstract:

:Topographical analysis of cerebral electrical activity was performed in 44 patients with hepatic encephalopathy. These patients were classified in 5 groups according to clinical criteria. Eight healthy subjects were used as a control group. All were studied in an awake, eyes closed, condition and some [Control Group (CG), Group 0 (G0), Group 1 (G1) and Group 2 (G2)] also in an awake, eyes open, condition. The awake, eyes closed, maps showed marked differences in the power spectral density (PSD) of the different bands, when comparing normal subjects with patients with several degrees of hepatic encephalopathy. These differences were related to the degree of clinical involvement, mainly in the alpha and delta PSD bands. The combination of a decreased alpha PSD, increased delta PSD, and decreased mean dominant frequency (MDF) allowed a clear discrimination between the different clinical groups. The differences observed between awake, eyes closed, and awake, eyes open, conditions were especially helpful to discriminate between CG subjects and G0, G1 and G2 patients.

journal_name

Brain Topogr

journal_title

Brain topography

authors

Sagalés T,Gimeno V,de la Calzada MD,Casellas F,Dolors Macià M,Villar Soriano M

doi

10.1007/BF01140590

subject

Has Abstract

pub_date

1990-04-01 00:00:00

pages

221-8

issue

3

eissn

0896-0267

issn

1573-6792

journal_volume

2

pub_type

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