Electrophysiological explorations of the cause and effect of inhibition of return in a cue-target paradigm.


:Facilitation and inhibition of return (IOR) are, respectively, faster and slower responses to a peripherally cued target. In a spatially uninformative peripheral cueing task, facilitation is normally observed when the interval between the cue and target stimulus, the stimulus onset asynchrony (SOA), is shorter than 250 ms, while IOR is normally observed when an SOA greater than 250 ms is used. Since Posner and Cohen's (Attention and performance X, 1984) seminal study, IOR has become an actively investigated component of orienting. In this study, using ERPs and the source localization algorithm, LORETA, we seek to examine the brain mechanisms involved in IOR by localizing the different stages of processing after the appearance of a cue that captures attention exogenously. Unlike previous ERP investigations of IOR, this study analyzes the neural activity (via EEG) produced in response to the cue, prior to the appearance of the target. Neural activations were approximately divided into three stages. In the early stage (110-240 ms), involved activations are in the prefrontal cortex, the bilateral intraparietal cortex, and the contralateral occipito-temporal cortex. In the middle stage (240-350 ms), activations are primarily found in the frontal cortex and the parietal cortex. In the late stage (350-650 ms), the main activations are in the occipito-parietal cortex, but unlike in the early stage, the activation areas have shifted to the hemisphere ipsilateral to the cued location. These findings indicate that IOR is related to both attentional and motor response processes and suggest that the time course of initial facilitation and IOR is concurrent and mediated by two neural networks. Building upon our results, electrophysiological, electroencephalographic, and behavioral results in the literature and extending previous spatial theories of IOR, we propose here a spatio-temporal theory of IOR based upon post-cue dynamics.


Brain Topogr


Brain topography


Tian Y,Klein RM,Satel J,Xu P,Yao D




Has Abstract


2011-06-01 00:00:00












  • Cortical processing of vowels and tones as measured by event-related desynchronization.

    abstract::Event-Related Desynchronization (ERD) and Synchronization (ERS) were studied in 20 normal subjects during a Sternberg-type auditory memory-scanning paradigm. Half of the subjects performed the experiment with vowels and the other half with tones as stimuli. The stimuli consisted of 100 msec long synthesized vowels and...

    journal_title:Brain topography

    pub_type: 杂志文章


    authors: Krause CM,Lang H,Laine M,Kuusisto M,Pörn B

    更新日期:1995-10-01 00:00:00

  • Topographic mapping and source localization of the pattern reversal visual evoked magnetic response.

    abstract::The topography of the visual evoked magnetic response (VEMR) to pattern reversal stimulation was studied in four normal subjects using a single channel BTI magnetometer. VEMRs were recorded from 20 locations over the occipital scalp and the topographic distribution of the most consistent component (P100M) studied. A s...

    journal_title:Brain topography

    pub_type: 杂志文章


    authors: Harding GF,Janday B,Armstrong RA

    更新日期:1991-10-01 00:00:00

  • Global Brain Involvement in Posterior Cortical Atrophy: Multimodal MR Imaging Investigation.

    abstract::Posterior cortical atrophy (PCA), considered a visual variant of Alzheimer's disease, has similar pathological characteristics yet shows a selective visual manifestation with relative preservation of other cortical areas, at least at early stages of disease. Using a gamut of imaging methods, we aim to evaluate the glo...

    journal_title:Brain topography

    pub_type: 杂志文章


    authors: Glick-Shames H,Keadan T,Backner Y,Bick A,Levin N

    更新日期:2020-09-01 00:00:00

  • Discrimination of Tourette Syndrome Based on the Spatial Patterns of the Resting-State EEG Network.

    abstract::Tourette syndrome (TS) is a neuropsychiatric disorder with childhood onset characterized by chronic motor and vocal tics; however, the current diagnosis of TS patients is subjective, as it is mainly assessed based on the parents' description alongside specific evaluations. The early and accurate diagnosis of TS based ...

    journal_title:Brain topography

    pub_type: 杂志文章


    authors: Duan K,Wu Q,Liao Y,Si Y,Bore JC,Li F,Tao Q,Lin L,Lei W,Hu X,Yao D,Pei C,Zhang T,Huang L,Xu P

    更新日期:2021-01-01 00:00:00

  • Change in Excitability of Corticospinal Pathway and GABA-Mediated Inhibitory Circuits of Primary Motor Cortex Induced by Contraction of Adjacent Hand Muscle.

    abstract::The present study examined whether the excitability of the corticospinal pathway and the GABA-mediated inhibitory circuits of the primary motor cortex that project onto the corticospinal neurons in the tonically contracting hand muscle are changed by tonic contraction of the adjacent hand muscle. The motor evoked pote...

    journal_title:Brain topography

    pub_type: 杂志文章


    authors: Jono Y,Iwata Y,Mizusawa H,Hiraoka K

    更新日期:2016-11-01 00:00:00

  • Reorganisation of the right occipito-parietal stream for auditory spatial processing in early blind humans. A transcranial magnetic stimulation study.

    abstract::It is well known that, following an early visual deprivation, the neural network involved in processing auditory spatial information undergoes a profound reorganization. In particular, several studies have demonstrated an extensive activation of occipital brain areas, usually regarded as essentially "visual", when ear...

    journal_title:Brain topography

    pub_type: 杂志文章


    authors: Collignon O,Davare M,Olivier E,De Volder AG

    更新日期:2009-05-01 00:00:00

  • Functional imaging of the brain using single photon emission computerized tomography (SPECT).

    abstract::The use of tracers is an important technique available for studying cerebral function. Changes in 'signal' are large, but as a result of its photon limited nature, the measurement of this signal is limited: spatially, temporally and in terms of accuracy. The most commonly used single photon (SPECT) system (as apposed ...

    journal_title:Brain topography

    pub_type: 杂志文章,评审


    authors: Todd-Pokropek AE

    更新日期:1992-01-01 00:00:00

  • A Comparison of Evoked and Non-evoked Functional Networks.

    abstract::The growing interest in brain networks to study the brain's function in cognition and diseases has produced an increase in methods to extract these networks. Typically, each method yields a different network. Therefore, one may ask what the resulting networks represent. To address this issue we consider electrocortico...

    journal_title:Brain topography

    pub_type: 杂志文章


    authors: Hebbink J,van Blooijs D,Huiskamp G,Leijten FSS,van Gils SA,Meijer HGE

    更新日期:2019-05-01 00:00:00

  • Comparing electrophysiological correlates of word production in immediate and delayed naming through the analysis of word age of acquisition effects.

    abstract::Most EEG studies analysing speech production with event related brain potential (ERP) have adopted silent metalinguistic tasks or delayed or tacit picture naming in order to avoid possible artefacts during motor preparation. A central issue in the interpretation of these results is whether the processes involved in th...

    journal_title:Brain topography

    pub_type: 杂志文章


    authors: Laganaro M,Perret C

    更新日期:2011-03-01 00:00:00

  • Alpha frequency, cognitive load and memory performance.

    abstract::EEG-signals were recorded from subjects as they performed a modified version of Schneider's and Shiffrin's memory search paradigm. The hypothesis was tested whether individual (centre of gravity) alpha frequency, termed IAF, is related to memory performance and/or attentional demands. The results show that memory perf...

    journal_title:Brain topography

    pub_type: 杂志文章


    authors: Klimesch W,Schimke H,Pfurtscheller G

    更新日期:1993-04-01 00:00:00

  • Assessing the effects of electroconvulsive therapy on cortical excitability by means of transcranial magnetic stimulation and electroencephalography.

    abstract::Electroconvulsive therapy (ECT) has significant short-term antidepressant effects on drug-resistant patients with severe major depression. Animal studies have demonstrated that electroconvulsive seizures produce potentiation-like synaptic remodeling in both sub-cortical and frontal cortical circuits. However, the elec...

    journal_title:Brain topography

    pub_type: 杂志文章


    authors: Casarotto S,Canali P,Rosanova M,Pigorini A,Fecchio M,Mariotti M,Lucca A,Colombo C,Benedetti F,Massimini M

    更新日期:2013-04-01 00:00:00

  • Improved accuracy of MEG localization in the temporal region with inclusion of volume current effects.

    abstract::We studied the magnetic field maps generated by six dipoles in the temporal region of a plastic skull filled with conducting gel. The data were processed with two mathematical models. One, using Biot-Savart's law, considered only the magnetic field generated by a localized current dipole, and the other considered a di...

    journal_title:Brain topography

    pub_type: 杂志文章


    authors: Rose DF,Ducla-Soares E,Sato S

    更新日期:1989-04-01 00:00:00

  • Increased gamma oscillations evoked by physically salient distracters are associated with schizotypy.

    abstract::Over the last decade, there has been growing interest in aberrant salience as a precursor of positive symptoms in schizophrenia. The present study investigates the neurophysiology of attentional capture by salient stimuli in the visual modality. Evoked oscillatory activity in the gamma frequency range (40 Hz) was asse...

    journal_title:Brain topography

    pub_type: 杂志文章


    authors: Kornmayer L,Leicht G,Mulert C

    更新日期:2015-01-01 00:00:00

  • Movement-Related Somatosensory Activity Is Altered in Patients with Multiple Sclerosis.

    abstract::During active movement the somatosensory cortical responses are often attenuated. This attenuation is referred to as movement-related sensory gating. It is well known that patients with multiple sclerosis (MS) have sensory processing deficits, and recent work has also suggested that these patients display impaired mot...

    journal_title:Brain topography

    pub_type: 杂志文章


    authors: Arpin DJ,Gehringer JE,Wilson TW,Kurz MJ

    更新日期:2018-07-01 00:00:00

  • Bridging the Gap Towards Awareness Detection in Disorders of Consciousness: An Experimental Study on the Mirror Neuron System.

    abstract::Advanced functional neuroimaging approaches dealing with motor imagery have disclosed covert cognitive processes in patients with disorders of consciousness (DoC). However, motor impairment and cognitive-motor dissociation can bias such approaches. Fourteen patients with post-traumatic DoC and ten healthy controls (HC...

    journal_title:Brain topography

    pub_type: 杂志文章


    authors: Naro A,Calabrò RS,Leo A,Russo M,Milardi D,Cannavò A,Manuli A,Buda A,Casella C,Bramanti P,Cacciola A,Bramanti A

    更新日期:2018-07-01 00:00:00

  • Electromyogenic artifacts and electroencephalographic inferences.

    abstract::Muscle or electromyogenic (EMG) artifact poses a serious risk to inferential validity for any electroencephalography (EEG) investigation in the frequency-domain owing to its high amplitude, broad spectrum, and sensitivity to psychological processes of interest. Even weak EMG is detectable across the scalp in frequenci...

    journal_title:Brain topography

    pub_type: 杂志文章,评审


    authors: Shackman AJ,McMenamin BW,Slagter HA,Maxwell JS,Greischar LL,Davidson RJ

    更新日期:2009-06-01 00:00:00

  • Source generators of mismatch negativity to multiple deviant stimulus types.

    abstract::The purpose of the present study was to investigate auditory stimulus feature processing and how neural generators might differ among the mismatch negativity (MMN) responses to intensity, frequency, and duration deviant stimuli. Data collected from 72 electrodes in twelve adult female subjects were analyzed. For each ...

    journal_title:Brain topography

    pub_type: 杂志文章


    authors: Schairer KS,Gould HJ,Pousson MA

    更新日期:2001-01-01 00:00:00

  • Neural dynamics of speech act comprehension: an MEG study of naming and requesting.

    abstract::The neurobiological basis and temporal dynamics of communicative language processing pose important yet unresolved questions. It has previously been suggested that comprehension of the communicative function of an utterance, i.e. the so-called speech act, is supported by an ensemble of neural networks, comprising lexi...

    journal_title:Brain topography

    pub_type: 杂志文章


    authors: Egorova N,Pulvermüller F,Shtyrov Y

    更新日期:2014-05-01 00:00:00

  • EEG Correlates of Relative Motion Encoding.

    abstract::A large portion of the visual cortex is organized retinotopically, but perception is usually non-retinotopic. For example, a reflector on the spoke of a bicycle wheel appears to move on a circular or prolate cycloidal orbit as the bicycle moves forward, while in fact it traces out a curtate cycloidal trajectory. The m...

    journal_title:Brain topography

    pub_type: 杂志文章


    authors: Thunell E,Plomp G,Ögmen H,Herzog MH

    更新日期:2016-03-01 00:00:00

  • EEG Artifact Removal in TMS Studies of Cortical Speech Areas.

    abstract::The combination of transcranial magnetic stimulation (TMS) and electroencephalography (EEG) is commonly applied for studying the effective connectivity of neuronal circuits. The stimulation excites neurons, and the resulting TMS-evoked potentials (TEPs) are recorded with EEG. A serious obstacle in this method is the g...

    journal_title:Brain topography

    pub_type: 杂志文章


    authors: Salo KS,Mutanen TP,Vaalto SMI,Ilmoniemi RJ

    更新日期:2020-01-01 00:00:00

  • Topographic mapping of somatosensory evoked potentials helps identify motor cortex more quickly in the operating room.

    abstract::Median nerve somatosensory evoked potentials were recorded from exposed cerebral cortex during craniotomies. This technique is valuable when knowledge of the motor cortex location can influence surgical decisions about resection limits or biopsy sites. Two different recording techniques were compared: strips of electr...

    journal_title:Brain topography

    pub_type: 杂志文章


    authors: Nuwer MR,Banoczi WR,Cloughesy TF,Hoch DB,Peacock W,Levesque MF,Black KL,Martin NA,Becker DP

    更新日期:1992-10-01 00:00:00

  • Optimal electrode placements for adequate spatial sampling of auditory evoked potentials.

    abstract::When evoked responses are used in clinical practice and research the measures that are most commonly considered are the latencies and amplitudes of EP components as measured at a single electrode site. Our recent studies have shown that multichannel recordings yield measures such as potential field asymmetry that may ...

    journal_title:Brain topography

    pub_type: 杂志文章


    authors: Sidman RD,Ford MR,Ramsey G

    更新日期:1994-04-01 00:00:00

  • Did You Listen to the Beat? Auditory Steady-State Responses in the Human Electroencephalogram at 4 and 7 Hz Modulation Rates Reflect Selective Attention.

    abstract::The acoustic envelope of human speech correlates with the syllabic rate (4-8 Hz) and carries important information for intelligibility, which is typically compromised in multi-talker, noisy environments. In order to better understand the dynamics of selective auditory attention to low frequency modulated sound sources...

    journal_title:Brain topography

    pub_type: 杂志文章


    authors: Jaeger M,Bleichner MG,Bauer AR,Mirkovic B,Debener S

    更新日期:2018-09-01 00:00:00

  • Reliability of Visual and Somatosensory Feedback in Skilled Movement: The Role of the Cerebellum.

    abstract::The integration of vision and somatosensation is required to allow for accurate motor behavior. While both sensory systems contribute to an understanding of the state of the body through continuous updating and estimation, how the brain processes unreliable sensory information remains to be fully understood in the con...

    journal_title:Brain topography

    pub_type: 杂志文章


    authors: Mizelle JC,Oparah A,Wheaton LA

    更新日期:2016-01-01 00:00:00

  • A new method of spatio-temporal topographic mapping by correlation coefficient of K-means cluster.

    abstract::It would be of the utmost interest to map correlated sources in the working human brain by Event-Related Potentials (ERPs). This work is to develop a new method to map correlated neural sources based on the time courses of the scalp ERPs waveforms. The ERP data are classified first by k-means cluster analysis, and the...

    journal_title:Brain topography

    pub_type: 杂志文章


    authors: Li L,Yao D

    更新日期:2007-07-01 00:00:00

  • Influence of a silastic ECoG grid on EEG/ECoG based source analysis.

    abstract::The simultaneous evaluation of the local electrocorticogram (ECoG) and the more broadly distributed electroencephalogram (EEG) from humans undergoing evaluation for epilepsy surgery has been shown to further the understanding of how pathologies give rise to spontaneous seizures. However, a well-known problem is that t...

    journal_title:Brain topography

    pub_type: 杂志文章


    authors: Lanfer B,Röer C,Scherg M,Rampp S,Kellinghaus C,Wolters C

    更新日期:2013-04-01 00:00:00

  • Neurophysiological Correlates of Attentional Fluctuation in Attention-Deficit/Hyperactivity Disorder.

    abstract::Cognitive performance in attention-deficit/hyperactivity disorder (ADHD) is characterised, in part, by frequent fluctuations in response speed, resulting in high reaction time variability (RTV). RTV captures a large proportion of the genetic risk in ADHD but, importantly, is malleable, improving significantly in a fas...

    journal_title:Brain topography

    pub_type: 杂志文章


    authors: Cheung CHM,McLoughlin G,Brandeis D,Banaschewski T,Asherson P,Kuntsi J

    更新日期:2017-05-01 00:00:00

  • Spatial enhancement of event-related potentials using multiresolution analysis.

    abstract::Multiresolution analysis is a potentially useful tool to enhance the brain's electrical fields (spatial distributions of event-related potentials (ERP)), and to bring out spatial features which may not be seen in the fields before enhancement. For comparing different images (slices from ERP of different subjects or fr...

    journal_title:Brain topography

    pub_type: 杂志文章


    authors: Wang K,Begleiter H,Porjesz B

    更新日期:1998-04-01 00:00:00

  • Procaine-induced increases in limbic rCBF correlate positively with increases in occipital and temporal EEG fast activity.

    abstract::Previous independent EEG and PET studies suggest that administration of intravenous procaine hydrochloride selectively activates limbic brain structures. To further elucidate procaine's effects and explore the relationship between quantitative EEG (qEEG) and regional cerebral blood flow (rCBF), we simultaneously recor...

    journal_title:Brain topography

    pub_type: 杂志文章


    authors: Parekh PI,Spencer JW,George MS,Gill DS,Ketter TA,Andreason P,Herscovitch P,Post RM

    更新日期:1995-04-01 00:00:00

  • Rhythmic Modulation of Entrained Auditory Oscillations by Visual Inputs.

    abstract::Temporal structure is ubiquitous in sensory signals, and the brain has been shown to robustly represent information about temporal structure in the phase of low frequency neural oscillations. In a related construct, the integration of information across the different senses has been proposed to be at least partly due ...

    journal_title:Brain topography

    pub_type: 杂志文章


    authors: Simon DM,Wallace MT

    更新日期:2017-09-01 00:00:00