Electrophysiological explorations of the cause and effect of inhibition of return in a cue-target paradigm.


:Facilitation and inhibition of return (IOR) are, respectively, faster and slower responses to a peripherally cued target. In a spatially uninformative peripheral cueing task, facilitation is normally observed when the interval between the cue and target stimulus, the stimulus onset asynchrony (SOA), is shorter than 250 ms, while IOR is normally observed when an SOA greater than 250 ms is used. Since Posner and Cohen's (Attention and performance X, 1984) seminal study, IOR has become an actively investigated component of orienting. In this study, using ERPs and the source localization algorithm, LORETA, we seek to examine the brain mechanisms involved in IOR by localizing the different stages of processing after the appearance of a cue that captures attention exogenously. Unlike previous ERP investigations of IOR, this study analyzes the neural activity (via EEG) produced in response to the cue, prior to the appearance of the target. Neural activations were approximately divided into three stages. In the early stage (110-240 ms), involved activations are in the prefrontal cortex, the bilateral intraparietal cortex, and the contralateral occipito-temporal cortex. In the middle stage (240-350 ms), activations are primarily found in the frontal cortex and the parietal cortex. In the late stage (350-650 ms), the main activations are in the occipito-parietal cortex, but unlike in the early stage, the activation areas have shifted to the hemisphere ipsilateral to the cued location. These findings indicate that IOR is related to both attentional and motor response processes and suggest that the time course of initial facilitation and IOR is concurrent and mediated by two neural networks. Building upon our results, electrophysiological, electroencephalographic, and behavioral results in the literature and extending previous spatial theories of IOR, we propose here a spatio-temporal theory of IOR based upon post-cue dynamics.


Brain Topogr


Brain topography


Tian Y,Klein RM,Satel J,Xu P,Yao D




Has Abstract


2011-06-01 00:00:00












  • Coupling between resting cerebral perfusion and EEG.

    abstract::While several studies have investigated interactions between the electroencephalography (EEG) and functional magnetic resonance imaging BOLD signal fluctuations, less is known about the associations between EEG oscillations and baseline brain haemodynamics, and few studies have examined the link between EEG power outs...

    journal_title:Brain topography

    pub_type: 杂志文章


    authors: O'Gorman RL,Poil SS,Brandeis D,Klaver P,Bollmann S,Ghisleni C,Lüchinger R,Martin E,Shankaranarayanan A,Alsop DC,Michels L

    更新日期:2013-07-01 00:00:00

  • Measurement processes and spatial principal components analysis.

    abstract::Spatial principal components analysis (SPCA) applied to the ongoing EEG yields factor loadings which, when mapped, consistently reveal symmetrical patterns resembling the spherical harmonics. In this paper, we consider the mechanisms responsible for these characteristic patterns. In doing so, we demonstrate that volum...

    journal_title:Brain topography

    pub_type: 杂志文章


    authors: Silberstein RB,Cadusch PJ

    更新日期:1992-07-01 00:00:00

  • Auditory Magnetoencephalographic Frequency-Tagged Responses Mirror the Ongoing Segmentation Processes Underlying Statistical Learning.

    abstract::Humans are highly sensitive to statistical regularities in their environment. This phenomenon, usually referred as statistical learning, is most often assessed using post-learning behavioural measures that are limited by a lack of sensibility and do not monitor the temporal dynamics of learning. In the present study, ...

    journal_title:Brain topography

    pub_type: 杂志文章


    authors: Farthouat J,Franco A,Mary A,Delpouve J,Wens V,Op de Beeck M,De Tiège X,Peigneux P

    更新日期:2017-03-01 00:00:00

  • Neuromagnetic activity during recognition of emotional pictures.

    abstract::Recently studied 'old' stimuli lead to larger frontal and parietal ERP responses than 'new' stimuli. The present experiment investigated the neuromagnetic correlates (MEG) of this 'old-new' effect and its modulation by emotional stimulus content. Highly arousing pleasant, highly arousing unpleasant and un-arousing neu...

    journal_title:Brain topography

    pub_type: 杂志文章


    authors: Kissler J,Hauswald A

    更新日期:2008-06-01 00:00:00

  • Real time processing of affective and cognitive stimuli in the human brain extracted from MEG signals.

    abstract::The magnetoencephalography (MEG) signal was recorded while subjects watched a video containing separate blocks of affective and cognitive advertisements and recalled slides extracted from the video a day later. An earlier behavioural study using the same video material showed that the affective advertisements were bet...

    journal_title:Brain topography

    pub_type: 杂志文章


    authors: Ioannides AA,Liu L,Theofilou D,Dammers J,Burne T,Ambler T,Rose S

    更新日期:2000-10-01 00:00:00

  • Identifying and quantifying multisensory integration: a tutorial review.

    abstract::We process information from the world through multiple senses, and the brain must decide what information belongs together and what information should be segregated. One challenge in studying such multisensory integration is how to quantify the multisensory interactions, a challenge that is amplified by the host of me...

    journal_title:Brain topography

    pub_type: 杂志文章,评审


    authors: Stevenson RA,Ghose D,Fister JK,Sarko DK,Altieri NA,Nidiffer AR,Kurela LR,Siemann JK,James TW,Wallace MT

    更新日期:2014-11-01 00:00:00

  • Scalp EEG is not a blur: it can see high frequency oscillations although their generators are small.

    abstract::High frequency oscillations (HFOs) are emerging as biomarkers of epileptogenicity. They have been shown to originate from small brain regions. Surprisingly, spontaneous HFOs can be recorded from the scalp. To understand how is it possible to observe these small events on the scalp, one avenue is the analysis of the co...

    journal_title:Brain topography

    pub_type: 杂志文章


    authors: Zelmann R,Lina JM,Schulze-Bonhage A,Gotman J,Jacobs J

    更新日期:2014-09-01 00:00:00

  • The effect of slice orientation on auditory FMRI at the level of the brainstem.

    abstract::Although auditory information is processed in several subcortical nuclei, most fMRI studies focus solely on the auditory cortex and do not take brainstem responses into account. One common difficulty in obtaining clear functional brainstem recordings is due to heartbeat related motion, manifested in the rostro-caudal ...

    journal_title:Brain topography

    pub_type: 杂志文章


    authors: Slabu LM

    更新日期:2010-09-01 00:00:00

  • A Finite-Difference Solution for the EEG Forward Problem in Inhomogeneous Anisotropic Media.

    abstract::Accurate source localization of electroencephalographic (EEG) signals requires detailed information about the geometry and physical properties of head tissues. Indeed, these strongly influence the propagation of neural activity from the brain to the sensors. Finite difference methods (FDMs) are head modelling approach...

    journal_title:Brain topography

    pub_type: 杂志文章


    authors: Cuartas Morales E,Acosta-Medina CD,Castellanos-Dominguez G,Mantini D

    更新日期:2019-03-01 00:00:00

  • Reaction Time in a Visual 4-Choice Reaction Time Task: ERP Effects of Motor Preparation and Hemispheric Involvement.

    abstract::Reaction time (RT), the most common measure of CNS efficiency, shows intra- and inter-individual variability. This may be accounted for by hemispheric specialization, individual neuroanatomy, and transient functional fluctuations between trials. To explore RT on these three levels, ERPs were measured in a visual 4-cho...

    journal_title:Brain topography

    pub_type: 杂志文章


    authors: Antonova I,van Swam C,Hubl D,Dierks T,Griskova-Bulanova I,Koenig T

    更新日期:2016-07-01 00:00:00

  • Quantified neurophysiology with mapping: statistical inference, exploratory and confirmatory data analysis.

    abstract::Topographic mapping of brain electrical activity has become a commonly used method in the clinical as well as research laboratory. To enhance analytic power and accuracy, mapping applications often involve statistical paradigms for the detection of abnormality or difference. Because mapping studies involve many measur...

    journal_title:Brain topography

    pub_type: 杂志文章,评审


    authors: Duffy FH,Jones K,Bartels P,Albert M,McAnulty GB,Als H

    更新日期:1990-10-01 00:00:00

  • Topographic mapping of somatosensory evoked potentials helps identify motor cortex more quickly in the operating room.

    abstract::Median nerve somatosensory evoked potentials were recorded from exposed cerebral cortex during craniotomies. This technique is valuable when knowledge of the motor cortex location can influence surgical decisions about resection limits or biopsy sites. Two different recording techniques were compared: strips of electr...

    journal_title:Brain topography

    pub_type: 杂志文章


    authors: Nuwer MR,Banoczi WR,Cloughesy TF,Hoch DB,Peacock W,Levesque MF,Black KL,Martin NA,Becker DP

    更新日期:1992-10-01 00:00:00

  • Mismatch negativity with visual-only and audiovisual speech.

    abstract::The functional organization of cortical speech processing is thought to be hierarchical, increasing in complexity and proceeding from primary sensory areas centrifugally. The current study used the mismatch negativity (MMN) obtained with electrophysiology (EEG) to investigate the early latency period of visual speech ...

    journal_title:Brain topography

    pub_type: 杂志文章


    authors: Ponton CW,Bernstein LE,Auer ET Jr

    更新日期:2009-05-01 00:00:00

  • Dynamics of brain activation during an explicit word and image recognition task: an electrophysiological study.

    abstract::Recent brain imaging studies suggest that semantic processing of words and images may share a common neural network, although modality-specific activation can also be observed. Other studies using event-related potentials (ERPs) report that brain responses to words and images may already differ at approximately 150 ms...

    journal_title:Brain topography

    pub_type: 杂志文章


    authors: Khateb A,Pegna AJ,Michel CM,Landis T,Annoni JM

    更新日期:2002-04-01 00:00:00

  • Perception of visual apparent movement and topographic analysis of related evoked potentials.

    abstract::Most of the studies in long-range apparent movement have been concerned with the psychophysical properties in central vision. However, apparent movement in peripheral vision is not clearly understood. This study focuses on the properties of the perception of apparent movement between central and peripheral vision. The...

    journal_title:Brain topography

    pub_type: 杂志文章


    authors: Tsuda R,Ueno S

    更新日期:1996-04-01 00:00:00

  • Neural Correlate of Anterograde Amnesia in Wernicke-Korsakoff Syndrome.

    abstract::The neural correlate of anterograde amnesia in Wernicke-Korsakoff syndrome (WKS) is still debated. While the capacity to learn new information has been associated with integrity of the medial temporal lobe (MTL), previous studies indicated that the WKS is associated with diencephalic lesions, mainly in the mammillary ...

    journal_title:Brain topography

    pub_type: 杂志文章


    authors: Nahum L,Pignat JM,Bouzerda-Wahlen A,Gabriel D,Liverani MC,Lazeyras F,Ptak R,Richiardi J,Haller S,Thorens G,Zullino DF,Guggisberg AG,Schnider A

    更新日期:2015-09-01 00:00:00

  • Plasticity in cortical motor upper-limb representation following stroke and rehabilitation: two longitudinal multi-joint FMRI case-studies.

    abstract::Motor dysfunction and recovery following stroke and rehabilitation are associated with primary motor cortex plasticity. To better track these effects we studied two patients with sub-acute sub-cortical stroke causing hemiparesis, who underwent an effective behavioral treatment termed Constraint Induced Movement Therap...

    journal_title:Brain topography

    pub_type: 杂志文章


    authors: Stark A,Meiner Z,Lefkovitz R,Levin N

    更新日期:2012-04-01 00:00:00

  • Neonatal Multisensory Processing in Preterm and Term Infants Predicts Sensory Reactivity and Internalizing Tendencies in Early Childhood.

    abstract::Multisensory processes include the capacity to combine information from the different senses, often improving stimulus representations and behavior. The extent to which multisensory processes are an innate capacity or instead require experience with environmental stimuli remains debated. We addressed this knowledge ga...

    journal_title:Brain topography

    pub_type: 杂志文章


    authors: Maitre NL,Key AP,Slaughter JC,Yoder PJ,Neel ML,Richard C,Wallace MT,Murray MM

    更新日期:2020-09-01 00:00:00

  • MEG study of short-term plasticity following multiple digit frequency discrimination training in humans.

    abstract::We trained four right-handed male subjects to detect small changes in the frequency of 21 Hz electrical stimulation applied to digits 2+3+4 of the right hand for 4 hours. Before and after the training, we recorded magnetoencephalographic (MEG) signals when the stimulation was applied to digit 2-5 separately using a wh...

    journal_title:Brain topography

    pub_type: 杂志文章


    authors: Liu L,Ioannides AA

    更新日期:2004-07-01 00:00:00

  • Comparing electrophysiological correlates of word production in immediate and delayed naming through the analysis of word age of acquisition effects.

    abstract::Most EEG studies analysing speech production with event related brain potential (ERP) have adopted silent metalinguistic tasks or delayed or tacit picture naming in order to avoid possible artefacts during motor preparation. A central issue in the interpretation of these results is whether the processes involved in th...

    journal_title:Brain topography

    pub_type: 杂志文章


    authors: Laganaro M,Perret C

    更新日期:2011-03-01 00:00:00

  • An event-related potential study on the impairment of automatic processing of auditory input in schizophrenia.

    abstract::Mismatch negativity (MMN) and P300 to auditory stimuli was carried out using global field power (GFP) in 25 schizophrenics and 25 normal controls. The peak latencies of MMN and P300 were significantly longer in schizophrenics than in normal controls, and the differences in MMN were marked in the frontal regions. The p...

    journal_title:Brain topography

    pub_type: 杂志文章


    authors: Shutara Y,Koga Y,Fujita K,Takeuchi H,Mochida M,Takemasa K

    更新日期:1996-04-01 00:00:00

  • Higher gait variability is associated with decreased parietal gray matter volume among healthy older adults.

    abstract::The objectives of this study were to examine the association of stride time variability (STV) with gray and white matter volumes in healthy older adults, and to determine the specific location of any parenchymal loss associated with higher STV. A total of 71 participants (mean age 69.0 ± 0.8 years; 59.7 % female) were...

    journal_title:Brain topography

    pub_type: 杂志文章


    authors: Beauchet O,Annweiler C,Celle S,Bartha R,Barthélémy JC,Roche F

    更新日期:2014-03-01 00:00:00

  • Focal abnormalities of P3 ERPs unveiled in patients with cortical lesions and primary progressive aphasia by average reference recordings.

    abstract::Event related potentials (ERPs) to an auditory odd-ball paradigm were recorded with the linked earlobe reference (LER) and with a computer calculated average reference (AR), excluding the two linked earlobe derivations. The study was performed in 30 patients with lesions of frontal, parietal, occipital cortex, unilate...

    journal_title:Brain topography

    pub_type: 临床试验,杂志文章


    authors: Onofrj M,Fulgente T,Malatesta G,Locatelli T

    更新日期:1994-07-01 00:00:00

  • Application of singular value decomposition to topographic analysis of flash-evoked potentials.

    abstract::Singular value decomposition is a robust numerical method for decomposing a matrix of multichannel EEG or EP data into a sharply reduced set of features with corresponding waveform, amplitude, and spatial vectors. In 19 normal subjects aged 19 to 40 years, the three largest features computed by the SVD algorithm accou...

    journal_title:Brain topography

    pub_type: 杂志文章


    authors: Harner RN,Riggio S

    更新日期:1989-10-01 00:00:00

  • Topographic mapping and source localization of the pattern reversal visual evoked magnetic response.

    abstract::The topography of the visual evoked magnetic response (VEMR) to pattern reversal stimulation was studied in four normal subjects using a single channel BTI magnetometer. VEMRs were recorded from 20 locations over the occipital scalp and the topographic distribution of the most consistent component (P100M) studied. A s...

    journal_title:Brain topography

    pub_type: 杂志文章


    authors: Harding GF,Janday B,Armstrong RA

    更新日期:1991-10-01 00:00:00

  • High and low stimulus-driven conflict engage segregated brain networks, not quantitatively different resources.

    abstract::Task-irrelevant information is constantly present in our environment and may interfere with the processing of the information necessary to achieve goal-directed behavior. While task goals determine which information must be suppressed, the demand for inhibitory control depends on the strength of the interference induc...

    journal_title:Brain topography

    pub_type: 杂志文章


    authors: Chouiter L,Dieguez S,Annoni JM,Spierer L

    更新日期:2014-03-01 00:00:00

  • Characterisation and reduction of the EEG artefact caused by the helium cooling pump in the MR environment: validation in epilepsy patient data.

    abstract::The EEG acquired simultaneously with fMRI is distorted by a number of artefacts related to the presence of strong magnetic fields, which must be reduced in order to allow for a useful interpretation and quantification of the EEG data. For the two most prominent artefacts, associated with magnetic field gradient switch...

    journal_title:Brain topography

    pub_type: 杂志文章


    authors: Rothlübbers S,Relvas V,Leal A,Murta T,Lemieux L,Figueiredo P

    更新日期:2015-03-01 00:00:00

  • Similarities between simulated spatial spectra of scalp EEG, MEG and structural MRI.

    abstract::Electrical dipoles oriented perpendicular to the cortical surface are the primary source of the scalp EEGs and MEGs. Thus, in particular, gyri and sulci structures on the cortical surface have a definite possibility to influence the EEGs and MEGs. This was examined by comparing the spatial power spectral density (PSD)...

    journal_title:Brain topography

    pub_type: 杂志文章


    authors: Ramon C,Freeman WJ,Holmes M,Ishimaru A,Haueisen J,Schimpf PH,Rezvanian E

    更新日期:2009-11-01 00:00:00

  • Cerebral dynamics of SEPS to non-painful and painful cutaneous electrical stimulation of the thenar and hypothenar.

    abstract::Early, middle and late latency somatosensory evoked potentials (SEPs) elicited by cutaneous electrical stimulation (painful vs. non-painful) of right and left hands were recorded. The aims were to study (1) if lifelong use of dominant right hand would result in different SEP topographies compared to non-dominant left ...

    journal_title:Brain topography

    pub_type: 杂志文章


    authors: Niddam DM,Arendt-Nielsen L,Chen AC

    更新日期:2000-01-01 00:00:00

  • A-magnetic optic-mechanical device to quantify finger kinematics for fMRI studies of bimanual coordination.

    abstract::Several fMRI studies have been performed to detect the neural correlates of stable bimanual coordination patterns in humans. Only few of those studies were accompanied by the on-line recording of the relative phase of fingers or hands, but none with high space and time resolutions. Conversely, the high-resolution reco...

    journal_title:Brain topography

    pub_type: 临床试验,杂志文章


    authors: De Luca C,Comani S,Di Donato L,Caulo M,Bertollo M,Romani GL

    更新日期:2007-04-01 00:00:00