Abstract:
:Group A rotaviruses (RVAs) are a major cause of serious intestinal disease in piglets. In this study, a novel pig strain was identified in a stool sample from China. The strain was designated RVA/Pig/China/LNCY/2016/G3P[13] and had a G3-P[13]-I5-R1-C1-M1-A8-N1-T1-E1-H1 genome. The viral protein 7 (VP7) and non-structural protein 4 (NSP4) genes of RVA/Pig/China/LNCY/2016/G3P[13] were closely related to cogent genes of human RVAs, suggesting that a reassortment between pig and human strains had occurred. Recombination analysis showed that RVA/Pig/China/LNCY/2016/G3P[13] is a natural recombinant strain between the P[23] and P[7] RVA strains, and crossover points for recombination were found at nucleotides (nt) 456 and 804 of the VP4 gene. Elucidating the biological characteristics of porcine rotavirus (PoRV) will be helpful for further analyses of the epidemic characteristics of this virus. The results of this study provide valuable information for RVA recombination and evolution and will facilitate future investigations into the molecular pathogenesis of RVAs.
journal_name
Transbound Emerg Disjournal_title
Transboundary and emerging diseasesauthors
Jing Z,Zhang X,Shi H,Chen J,Shi D,Dong H,Feng Ldoi
10.1111/tbed.12756subject
Has Abstractpub_date
2018-04-01 00:00:00pages
e317-e328issue
2eissn
1865-1674issn
1865-1682journal_volume
65pub_type
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journal_title:Transboundary and emerging diseases
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journal_title:Transboundary and emerging diseases
pub_type: 杂志文章
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journal_title:Transboundary and emerging diseases
pub_type: 杂志文章,评审
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journal_title:Transboundary and emerging diseases
pub_type: 杂志文章
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journal_title:Transboundary and emerging diseases
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journal_title:Transboundary and emerging diseases
pub_type: 杂志文章
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journal_title:Transboundary and emerging diseases
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journal_title:Transboundary and emerging diseases
pub_type: 杂志文章
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journal_title:Transboundary and emerging diseases
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journal_title:Transboundary and emerging diseases
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journal_title:Transboundary and emerging diseases
pub_type: 杂志文章
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journal_title:Transboundary and emerging diseases
pub_type: 杂志文章
doi:10.1111/tbed.13588
更新日期:2020-07-01 00:00:00
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journal_title:Transboundary and emerging diseases
pub_type: 杂志文章
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journal_title:Transboundary and emerging diseases
pub_type: 杂志文章
doi:10.1111/j.1865-1682.2007.01009.x
更新日期:2008-01-01 00:00:00
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journal_title:Transboundary and emerging diseases
pub_type: 杂志文章
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journal_title:Transboundary and emerging diseases
pub_type: 杂志文章
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更新日期:2020-07-01 00:00:00
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pub_type: 杂志文章
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更新日期:2020-10-23 00:00:00
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pub_type: 杂志文章
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journal_title:Transboundary and emerging diseases
pub_type: 杂志文章
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更新日期:2018-12-01 00:00:00
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journal_title:Transboundary and emerging diseases
pub_type: 杂志文章
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journal_title:Transboundary and emerging diseases
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journal_title:Transboundary and emerging diseases
pub_type: 杂志文章
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journal_title:Transboundary and emerging diseases
pub_type: 杂志文章
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更新日期:2019-01-01 00:00:00
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journal_title:Transboundary and emerging diseases
pub_type: 杂志文章
doi:10.1111/j.1865-1682.2012.01311.x
更新日期:2013-02-01 00:00:00
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journal_title:Transboundary and emerging diseases
pub_type: 杂志文章
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更新日期:2016-04-01 00:00:00
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journal_title:Transboundary and emerging diseases
pub_type: 杂志文章
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journal_title:Transboundary and emerging diseases
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journal_title:Transboundary and emerging diseases
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