Abstract:
:Staphylococcus aureus is a versatile and highly adaptable pathogen associated with a wide range of infectious diseases in humans and animals. In the last decades, concern has increased worldwide due to the emergence and spread of methicillin-resistant S. aureus (MRSA) strains shortly after this drug became a therapeutic option. In this study, we report the genomic features of the first mecC-mediated, β-lactam resistant MRSA strain associated with livestock in Brazil and in the American continent. Three clonally related phenotypic MRSA isolates originated from a dairy herd were confirmed by polymerase chain reaction as mecC-harbouring MRSA isolates. Whole-genome sequencing was performed by Illumina Miseq platform. Downstream analyses showed that the strain was identified as the sequence type 126 (ST126) and spa type t605. In silico analysis revealed a mecC homolog gene in the orfX region associated with different penicillin-binding proteins. Moreover, genes encoding for efflux pump systems (arlR, mepR, LmrS, norA and mgrA), and antibiotic inactivation enzymes (blaZ and FosB) were also detected. Virulence analyses revealed that the strain harbours genes encoding for exoenzymes (aur, splA, splB and splE), toxin (hlgA, hlgB, hlgC, lukD and lukE) and enterotoxin (sea). The epidemiologic and genomic information provided by this study will support further epidemiological and evolutionary investigations to understand the origin and dissemination of mecC-MRSA among animals and its impact on public health.
journal_name
Transbound Emerg Disjournal_title
Transboundary and emerging diseasesauthors
Silva JG,Araujo WJ,Leite EL,Dias LM,Vasconcelos PC,Silva NMV,Oliveira RP,Sena MJ,Oliveira CJB,Mota RAdoi
10.1111/tbed.13771subject
Has Abstractpub_date
2020-08-06 00:00:00eissn
1865-1674issn
1865-1682pub_type
杂志文章abstract::Hydranencephaly, the almost complete absence of the cerebral parenchyma, induced by infection with modified live bluetongue virus (BTV) crossing the placenta has previously been reported in sheep and rarely in cattle in the USA and in South Africa. The current study describes 29 cases of hydranencephaly in bovine foet...
journal_title:Transboundary and emerging diseases
pub_type: 杂志文章
doi:10.1111/j.1865-1682.2008.01034.x
更新日期:2008-09-01 00:00:00
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journal_title:Transboundary and emerging diseases
pub_type: 杂志文章
doi:10.1111/j.1865-1682.2008.01022.x
更新日期:2008-05-01 00:00:00
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journal_title:Transboundary and emerging diseases
pub_type: 杂志文章
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journal_title:Transboundary and emerging diseases
pub_type: 杂志文章
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更新日期:2017-12-01 00:00:00
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journal_title:Transboundary and emerging diseases
pub_type: 杂志文章
doi:10.1111/tbed.12599
更新日期:2017-02-01 00:00:00
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journal_title:Transboundary and emerging diseases
pub_type: 杂志文章,评审
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更新日期:2019-03-01 00:00:00
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journal_title:Transboundary and emerging diseases
pub_type: 杂志文章
doi:10.1111/tbed.12071
更新日期:2014-12-01 00:00:00
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journal_title:Transboundary and emerging diseases
pub_type: 杂志文章
doi:10.1111/j.1865-1682.2010.01104.x
更新日期:2010-04-01 00:00:00
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journal_title:Transboundary and emerging diseases
pub_type: 杂志文章
doi:10.1111/tbed.12885
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journal_title:Transboundary and emerging diseases
pub_type: 杂志文章
doi:10.1111/tbed.13631
更新日期:2020-11-01 00:00:00
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journal_title:Transboundary and emerging diseases
pub_type: 杂志文章,评审
doi:10.1111/j.1865-1682.2011.01300.x
更新日期:2012-03-01 00:00:00
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journal_title:Transboundary and emerging diseases
pub_type: 杂志文章,评审
doi:10.1111/tbed.12159
更新日期:2013-11-01 00:00:00
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journal_title:Transboundary and emerging diseases
pub_type: 杂志文章
doi:10.1111/tbed.13785
更新日期:2020-08-12 00:00:00
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journal_title:Transboundary and emerging diseases
pub_type: 杂志文章
doi:10.1111/tbed.12461
更新日期:2017-06-01 00:00:00
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journal_title:Transboundary and emerging diseases
pub_type: 杂志文章
doi:10.1111/j.1865-1682.2007.01016.x
更新日期:2008-01-01 00:00:00
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journal_title:Transboundary and emerging diseases
pub_type: 杂志文章
doi:10.1111/tbed.13360
更新日期:2020-01-01 00:00:00
abstract::Swine enteric coronaviruses, including porcine epidemic diarrhoea virus (PEDV) and porcine deltacoronavirus (PDCoV), have emerged and spread throughout the North American swine industry over the last four years. These diseases cause significant losses within the pork industry and within the first year after PEDV intro...
journal_title:Transboundary and emerging diseases
pub_type: 杂志文章
doi:10.1111/tbed.12823
更新日期:2018-06-01 00:00:00
abstract::From June to July 2017, six Seneca Valley virus (SVV) strains were isolated from swine herds exhibiting SVV-associated porcine idiopathic vesicular disease (PIVD) in Guangdong province, China. Complete genomic sequences of these six newly identified strains were genetically and phylogenetically analysed. The results r...
journal_title:Transboundary and emerging diseases
pub_type: 杂志文章
doi:10.1111/tbed.12839
更新日期:2018-06-01 00:00:00
abstract::In previous studies, Theileria annulata surface protein (TaSP) was identified as an immunodominant antigen and successfully used to develop and validate a recombinant-protein-based ELISA for the detection of circulating antibodies in serum of T. annulata-infected animals. In this study, the same antigen was used to de...
journal_title:Transboundary and emerging diseases
pub_type: 杂志文章
doi:10.1111/j.1865-1682.2008.01036.x
更新日期:2008-08-01 00:00:00
abstract::This article shows that socio-economic factors, defined here as practices, knowledge, interests, beliefs and experiences have a role in the adoption of brucellosis control strategies in the Bajío region, Mexico. We combined qualitative and quantitative methods to show that socio-economic factors with regard to goat hu...
journal_title:Transboundary and emerging diseases
pub_type: 杂志文章
doi:10.1111/tbed.12359
更新日期:2017-02-01 00:00:00
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journal_title:Transboundary and emerging diseases
pub_type: 杂志文章
doi:10.1111/tbed.12678
更新日期:2018-02-01 00:00:00
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journal_title:Transboundary and emerging diseases
pub_type: 杂志文章
doi:10.1111/tbed.13991
更新日期:2021-01-16 00:00:00
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journal_title:Transboundary and emerging diseases
pub_type: 杂志文章
doi:10.1111/tbed.12590
更新日期:2017-12-01 00:00:00
abstract::First described in 1955 in New Jersey, epizootic haemorrhagic disease (EHD) causes a severe clinical disease in wild and domestic ruminants worldwide. Epizootic haemorrhagic disease outbreaks occur in deer populations each year from summer to late autumn. The etiological agent is EHD virus (EHDV) which is a double-str...
journal_title:Transboundary and emerging diseases
pub_type: 杂志文章
doi:10.1111/tbed.13257
更新日期:2019-09-01 00:00:00
abstract::Myxoma virus (MYXV) is the aetiological agent of myxomatosis, a systemic, mostly lethal disease that affects European rabbits. Vaccination against it, although widespread, has not been completely effective and disease outbreaks still take place on farms which carry out vaccination programmes. Since some of these cases...
journal_title:Transboundary and emerging diseases
pub_type: 杂志文章
doi:10.1111/tbed.13809
更新日期:2020-08-19 00:00:00
abstract::Porcine epidemic diarrhoea virus (PEDV) is an emerging and re-emerging epizootic virus of swine that causes substantial economic losses to the pig industry in China and other countries. The variations in the virus, and its co-infections with other enteric viruses, have contributed to the poor control of PEDV infection...
journal_title:Transboundary and emerging diseases
pub_type: 杂志文章
doi:10.1111/tbed.13439
更新日期:2020-05-01 00:00:00
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journal_title:Transboundary and emerging diseases
pub_type: 杂志文章
doi:10.1111/tbed.12928
更新日期:2018-12-01 00:00:00
abstract::The current COVID-19 global pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) of probable bat origin, has highlighted the ongoing need for a One Health response to emerging zoonotic disease events. Understanding the human-animal interface and its relevance to disease transmission remains...
journal_title:Transboundary and emerging diseases
pub_type: 杂志文章
doi:10.1111/tbed.13885
更新日期:2020-10-22 00:00:00
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journal_title:Transboundary and emerging diseases
pub_type: 杂志文章
doi:10.1111/tbed.13892
更新日期:2020-10-23 00:00:00
abstract::The aim of our study was to determine species and genotypes of Cryptosporidium in patients suffering from immunosuppressive illnesses, but also in immunocompetent patients suffering from diarrhoea. A total of 80 samples of faeces were collected from both immunosuppressed and immunocompetent patients. The immunosuppres...
journal_title:Transboundary and emerging diseases
pub_type: 杂志文章
doi:10.1111/tbed.13009
更新日期:2019-01-01 00:00:00