当前位置： SCI文献检索 > JOURNAL OF THE NEUROLOGICAL SCIENCES期刊下所有文献 > Resumption of antiplatelet therapy in patients with primary intracranial hemorrhage-benefits and risks: A meta-analysis of cohort studies.

Resumption of antiplatelet therapy in patients with primary intracranial hemorrhage-benefits and risks: A meta-analysis of cohort studies.

Abstract：

BACKGROUND:Clinical disagreement over antiplatelet (AP) resumption in patients with primary intracranial hemorrhage (ICH) has long existed. This meta-analysis aimed to evaluate the benefits of AP resumption on preventing ischemic or thromboembolic events against its risks of promoting ICH recurrence or hematoma expansion. METHODS:All relevant articles published in Pubmed, EMBASE, the Cochrane Library, and Science Direct from January 1950 to March 2017 were sourced, and the combined relative risk (RR) was calculated. RESULTS:A total of 3648 articles were found, and after screening, 6 cohort studies including 1916 patients were included in this meta-analysis. AP resumption was associated with a decreased risk of ischemic or thromboembolic events (RR, 0.61; 95% confidence interval (CI), 0.48-0.79; P<0.01). There was no significant difference in the risk of ICH recurrence or hematoma expansion between patients with or without AP resumption (RR, 0.84; 95% CI, 0.47-1.51; P=0.56). CONCLUSION:AP resumption in patients with primary ICH reduced the risk of ischemic or thromboembolic events, without significant increase of risk of ICH recurrence or hematoma expansion.

journal_name

J Neurol Sci

journal_title

Journal of the neurological sciences

authors

Ding X,Liu X,Tan C,Yin M,Wang T,Liu Y,Mo L,Wei X,Tan X,Deng F,Chen L

doi

10.1016/j.jns.2017.11.009

subject

Has Abstract

pub_date

2018-01-15 00:00:00

pages

133-138

eissn

0022-510X

issn

1878-5883

pii

S0022-510X(17)34441-6

journal_volume

384

pub_type

杂志文章,meta分析,评审

相关文献

JOURNAL OF THE NEUROLOGICAL SCIENCES文献大全
  • Improved strength on 5-hydroxytryptophan and carbidopa in spinal cord atrophy.

    abstract：:There is ample evidence of an important role of descending serotonergic projections in modulating spinal motor neuron activation and firing, and experimental studies suggest that 5-HT receptor stimulation can improve motor function after spinal cord injury; however, relevant clinical data is sorely lacking. We describ...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2017.04.047

    authors： Horvath GA,Meisner L,Selby K,Stowe R,Carleton B

    更新日期：2017-07-15 00:00:00

  • The contribution of magnetic resonance imaging in the differential diagnosis of optic nerve damage.

    abstract：:In this paper we review the findings of magnetic resonance imaging (MRI) in optic neuritis and visual dysfunction due to other optic neuropathies. With advances in MRI technology, it has become possible to visualise optic nerve pathology. STIR and RARE sequences, contrast-enhanced sequences, and phased array surface c...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章,评审

    doi：10.1016/s0022-510x(99)00272-5

    authors： Gass A,Moseley IF

    更新日期：2000-01-15 00:00:00

  • Considering risk factors for the effectiveness of translational therapies in brain stroke.

    abstract：:Multiple studies on cerebral ischemia have been performed in animal models to propose different strategies of neuroprotection that mitigate either the early or late consequences of the disease. These therapies have been successful in reducing the volume of infarction, the proinflammatory cascade, and the amount of fre...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章,评审

    doi：10.1016/j.jns.2019.116547

    authors： Gutiérrez-Vargas JA,Cardona-Gómez GP

    更新日期：2020-01-15 00:00:00

  • Lack of APOE Christchurch variant in five age of onset outliers with PSEN1, PSEN2 Alzheimer's disease and MAPT frontotemporal dementia.

    abstract：INTRODUCTION:Age of onset modifiers are of considerable importance in Alzheimer's and related dementias. Arboleda-Valesquez et al., reporting on a single PSEN1 subject, suggested that homozygosity for the Christchurch variant of APOE could represent such a modifier. METHODS:We studied APOE Christchurch and Kloth-VS ge...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2020.117143

    authors： Yu CE,Chen S,Jayadev S,Bird T

    更新日期：2020-11-15 00:00:00

  • Yes/yes head tremor without appendicular tremor after bilateral cerebellar infarction.

    abstract：:We report a 67-year-old man who developed yes/yes head tremor without appendicular tremor six weeks after right occipital and bilateral cerebellar infarction. The tremor was resting-postural. Its activity increased with excitement, decreased either after ethanol, lateroflexion or rest and stopped at sleep. Four-vessel...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：

    authors： Finsterer J,Muellbacher W,Mamoli B

    更新日期：1996-08-01 00:00:00

  • High b value q-space-analyzed diffusion MRI in vascular dementia: a preliminary study.

    abstract：:High b value diffusion weighted magnetic resonance imaging (high-b DWI) was used to characterize white matter changes in the brain of patients with vascular dementia (VaD). Hyperintense white matter areas detected by T2-weighted magnetic resonance imaging (MRI) represent lesions, also termed leukoaraiosis that are ver...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/s0022-510x(02)00297-6

    authors： Assaf Y,Mayzel-Oreg O,Gigi A,Ben-Bashat D,Mordohovitch M,Verchovsky R,Reider-Groswasser II,Hendler T,Graif M,Cohen Y,Korczyn AD

    更新日期：2002-11-15 00:00:00

  • Median and tibial somatosensory evoked potentials. Changes in short- and long-latency components in patients with lesions of the thalamus and thalamo-cortical radiations.

    abstract：:Alterations in short- and long-latency components of median and tibial somatosensory evoked potentials (SEPs) were studied in patients with lesions in the thalamus and thalamo-cortical radiations. When the lesions were located primarily in the ventro-posterior thalamus, the SEP changes consisted of the following combi...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/0022-510x(86)90169-3

    authors： Chu NS

    更新日期：1986-12-01 00:00:00

  • Brain MRI findings in patients with Fabry disease.

    abstract：BACKGROUND:To evaluate the presence of ischemic and hemorrhagic lesions in brain MRI of patients with Fabry disease (FD). METHODS:Brain MRI studies in 46 consecutive patients were evaluated using classic sequences as well as GRE-weighted images, for ischemic lesions and chronic microbleed detection. Of the 36 adult pa...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2011.03.020

    authors： Reisin RC,Romero C,Marchesoni C,Nápoli G,Kisinovsky I,Cáceres G,Sevlever G

    更新日期：2011-06-15 00:00:00

  • Congenital fiber type disproportion myopathy caused by LMNA mutations.

    abstract：:A boy, who had shown muscle weakness and hypotonia from early childhood and fiber type disproportion (FTD) with no dystrophic changes on muscle biopsy, was initially diagnosed as having congenital fiber type disproportion (CFTD). Subsequently, he developed cardiac conduction blocks. We reconsidered the diagnosis as po...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2014.02.036

    authors： Kajino S,Ishihara K,Goto K,Ishigaki K,Noguchi S,Nonaka I,Osawa M,Nishino I,Hayashi YK

    更新日期：2014-05-15 00:00:00

  • The spinal cord in lightning injury: a report of two cases.

    abstract：:We present 2 patients in whom the predominant neurological complication following lightning strike was spinal cord injury. One patient, who was followed for 5 years, showed clinical, electrophysiologic and MRI evidence of cervical spinal cord injury. This patient had significant recovery, which in part, may be related...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2008.09.020

    authors： Lakshminarayanan S,Chokroverty S,Eshkar N,Grewal R

    更新日期：2009-01-15 00:00:00

  • Conditions of iodine contrast transfer from lumbosacral CSF to blood.

    abstract：PURPOSE:To determine conditions which influence transfer of iopamidol from lumbosacral cerebrospinal fluid (CSF) to blood. METHODS:Iopamidol transfer was measured in 32 patients over 180 min after radiculography and compared with patient variables. RESULTS:Iopamidol transfer began early in 12 patients, more slowly in...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/s0022-510x(02)00340-4

    authors： Seyfert S,Koch HC,Kunzmann V

    更新日期：2003-01-15 00:00:00

  • Mitochondria, metabolic disturbances, oxidative stress and the kynurenine system, with focus on neurodegenerative disorders.

    abstract：:The mitochondria have several important functions in the cell. A mitochondrial dysfunction causes an abatement in ATP production, oxidative damage and the induction of apoptosis, all of which are involved in the pathogenesis of numerous disorders. This review focuses on mitochondrial dysfunctions and discusses their c...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章,评审

    doi：10.1016/j.jns.2007.01.033

    authors： Sas K,Robotka H,Toldi J,Vécsei L

    更新日期：2007-06-15 00:00:00

  • Histopathological evidence that hippocampal atrophy following status epilepticus is a result of neuronal necrosis.

    abstract：:Medial temporal lobe epilepsy is commonly associated with hippocampal atrophy on MRI and hippocampal sclerosis on histopathological examination of surgically-resected specimens. Likewise, it is well-established that prolonged seizures and status epilepticus can lead to hippocampal edema as noted on MRI. In this paper,...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2013.08.016

    authors： Kumar G,Mittal S,Moudgil SS,Kupsky WJ,Shah AK

    更新日期：2013-11-15 00:00:00

  • Bilateral basal ganglia lesions as initial manifestation of CNS invasion in adult T-cell leukemia.

    abstract：:We describe the case of a 67-year-old man who exhibited unsteadiness in walking, topographical disorientation, and urinary incontinence. Neurological examination revealed somnolence and mild weakness in the lower limbs with slight rigidity in the upper limbs. Cerebrospinal fluid examination showed pleocytosis with "fl...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2013.01.035

    authors： Matsuo Y,Yamashita S,Honda S,Nakajima M,Ueda A,Hirahara T,Yamashita T,Maeda Y,Hirano T,Ando Y

    更新日期：2013-04-15 00:00:00

  • Cerebrovascular reactivity after treatment of unruptured intracranial aneurysms--A transcranial Doppler sonography and acetazolamide study.

    abstract：BACKGROUND:Cerebrovascular reactivity (CVR) is defined as the change in cerebral blood flow, or blood velocity, in response to a vasoactive stimulus. There is a possible association between impaired CVR and vasospasm after aneurysmal subarachnoid hemorrhage. Most studies on CVR and vasospasm have used healthy subjects ...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2015.12.024

    authors： Bøthun ML,Haaland ØA,Logallo N,Svendsen F,Thomassen L,Helland CA

    更新日期：2016-04-15 00:00:00

  • Multi-unit activity suppression and sensorimotor deficits after endothelin-1-induced middle cerebral artery occlusion in conscious rats.

    abstract：:Conscious Wistar rats with stereotaxically and unilaterally implanted cannula just above the middle cerebral artery (MCA) were injected with the powerful vasoconstrictor peptide endothelin-1 (ET1, 60 pmol in 3 microl). The purpose was to examine the long-term (from the 1st to the 14th day) changes in neuronal bioelect...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/s0022-510x(03)00102-3

    authors： Moyanova S,Kirov R,Kortenska L

    更新日期：2003-08-15 00:00:00

  • A patient with anti-aquaporin 4 antibody presenting hypersomnolence as the initial symptom and symmetrical hypothalamic lesions.

    abstract：:Here we report a case with positive serum anti-aquaporin 4 (AQP4) antibody who presented with hypersomnolence, symmetrical hypothalamic lesions and a reduced CSF orexin (hypocretin) level without optic nerve and spinal cord lesions on MRI. All of the symptoms, MRI finding and CSF orexin level improved simultaneously a...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2011.08.031

    authors： Deguchi K,Kono S,Deguchi S,Morimoto N,Ikeda M,Kurata T,Ikeda Y,Matsuura T,Kanbayashi T,Takahashi T,Abe K

    更新日期：2012-01-15 00:00:00

  • Histological evidence of delayed ischemic brain tissue damage in the rat double-hemorrhage model.

    abstract：:The rat double-SAH model is one of the standard models to simulate delayed cerebral vasospasm (CVS) in humans. However, the proof of delayed ischemic brain damage is missing so far. Our objective was, therefore, to determine histological changes in correlation with the development of symptomatic and perfusion weighted...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2010.03.023

    authors： Güresir E,Raabe A,Jaiimsin A,Dias S,Raab P,Seifert V,Vatter H

    更新日期：2010-06-15 00:00:00

  • Longitudinally extensive transverse myelitis immune-mediated in aquaporin-4 antibody negative patients: Disease heterogeneity.

    abstract：BACKGROUND:Longitudinally extensive transverse myelitis (LETM) is a frequent manifestation of neuromyelitis optica spectrum disorder (NMOSD). However, it can also occur in other immune-mediated diseases of the central nervous system (CNS). Positive aquoporin-4 antibodies (AQP4-ab) predict higher relapse rate after LETM...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/j.jns.2016.12.033

    authors： Carnero Contentti E,Hryb JP,Morales S,Gomez A,Chiganer E,Di Pace JL,Lessa C,Perassolo M

    更新日期：2017-02-15 00:00:00

  • Aluminum affects interconnections between aggregates of cultured hippocampal neurons. Neurotoxicity of aluminum in vitro.

    abstract：:The effect of aluminum (Al) was studied in an in vitro system of cultured hippocampal neurons from fetal rats in a chemically defined medium. Neuronal aggregates interconnected by neurites were detected light and electron microscopically in control and Al-treated cultures. In the Al-treated cultures disruptions of the...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/0022-510x(89)90186-x

    authors： van Welsum RA,van der Voet GB,Marani E,van Keep JP,de Wolff FA

    更新日期：1989-11-01 00:00:00

  • Nutritional optic neuropathies.

    abstract：:Nutritional deficiency may be the cause of a genuine optic neuropathy, sometimes associated with involvement of the peripheral nervous system. Nutritional optic neuropathies are usually bilateral, painless, chronic, insidious and slowly progressive. Most often, they present as a non-specific retrobulbar optic neuropat...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章,评审

    doi：10.1016/j.jns.2007.06.038

    authors： Orssaud C,Roche O,Dufier JL

    更新日期：2007-11-15 00:00:00

  • Antibodies against myelin oligodendrocyte glycoprotein in the cerebrospinal fluid of multiple sclerosis patients.

    abstract：:Antibodies against myelin oligodendrocyte glycoprotein (MOG) mediate demyelination in experimental autoimmune encephalomyelitis (EAE) in different animal species and are implicated in the immunopathogenesis of multiple sclerosis (MS). In order to evaluate the anti-MOG response, we have analyzed the cerebrospinal fluid...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/s0022-510x(03)00066-2

    authors： Markovic M,Trajkovic V,Drulovic J,Mesaros S,Stojsavljevic N,Dujmovic I,Mostarica Stojkovic M

    更新日期：2003-07-15 00:00:00

  • Herpes simplex virus encephalitis in a mouse model: PCR evidence for CNS latency following acute infection.

    abstract：:We have used a mouse model of herpes simplex encephalitis produced by intranasal inoculation of virus to study the expression of viral immediate early, early and late genes and latency associated transcript (LAT) in trigeminal ganglia and brain at various times after inoculation. A PCR technique was used to detect the...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/0022-510x(94)90068-x

    authors： Drummond CW,Eglin RP,Esiri MM

    更新日期：1994-12-20 00:00:00

  • Peripheral autonomic surface potential. A quantitative technique for recording sympathetic conduction in man.

    abstract：:Using EMG equipment with time locked recording and standard averaging facilities we were able to record a previously poorly defined skin potential. The potential, termed by us the peripheral autonomic surface potential (PASP), was recorded from the palmar surface of the hand and the plantar surface of the foot in 30 n...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/0022-510x(85)90120-0

    authors： Knezevic W,Bajada S

    更新日期：1985-02-01 00:00:00

  • Transplanted human bone marrow cells generate new brain cells.

    abstract：:Multiple studies have reported that adult cells of bone marrow origin can differentiate into muscle, skin, liver, lung, epithelial cells, and neurons. To determine whether such cells might produce neurons and other cells in the human brain, we examined paraffin sections from female patients who had received bone marro...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章,评审

    doi：10.1016/j.jns.2005.03.017

    authors： Crain BJ,Tran SD,Mezey E

    更新日期：2005-06-15 00:00:00

  • Glycogen accumulated in the brain following insults is not degraded during a subsequent period of ischemia.

    abstract：:The primary objective of this study was to attempt to induce excessive intraglial acidosis during ischemia by subjecting rats to an initial insult which leads to post insult accumulation of glycogen, presumed to accumulate primarily in astrocytes. The initial insults were 15 min of transient forebrain ischemia, 30 min...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/0022-510x(96)82226-x

    authors： Folbergrova J,Katsura KI,Siesjo BK

    更新日期：1996-04-01 00:00:00

  • Selective staining of a subset of Purkinje cells in the human cerebellum with monoclonal antibody mabQ113.

    abstract：:MabQ113 is a monoclonal antibody raised against rat cerebellum which selectively strains Purkinje cells. Likewise, in mabQ113-immunoperoxidase stained sections of human cerebellum, deposits of reaction product are found only in the Purkinje cells. The dendritic arborizations, cell body, and axonal processes are immuno...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/0022-510x(85)90166-2

    authors： Plioplys AV,Thibault J,Hawkes R

    更新日期：1985-10-01 00:00:00

  • Absence of neuronal and glial proteins in human and rat leptomeninges in situ.

    abstract：:Human leptomeningeal (arachnoid and pia mater) cells in culture have been demonstrated in replicated studies to express typical neuronal proteins such as neurofilament protein and neuron-specific enolase. In addition, they can express glial fibrillary acidic protein. The present study examines the possibility that neu...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章

    doi：10.1016/s0022-510x(96)00189-x

    authors： Calingasan NY,Bernstein JJ,Blass JP

    更新日期：1996-12-01 00:00:00

  • Novel drug development for amyotrophic lateral sclerosis.

    abstract：:Amyotrophic lateral sclerosis (ALS) has become an increasingly attractive area for the pharmaceutical industry, the most experimentally tractable of the neurodegenerative diseases. Mechanisms underlying cell death in ALS are likely to be important in more common but more complex disorders. Riluzole, the only drug laun...

    journal_title：Journal of the neurological sciences

    pub_type： 杂志文章,评审

    doi：10.1016/s0022-510x(00)00419-6

    authors： Hurko O,Walsh FS

    更新日期：2000-11-01 00:00:00

  • Short-term motor improvement after sub-threshold 5-Hz repetitive transcranial magnetic stimulation of the primary motor hand area in Parkinson's disease.

    abstract：:Ten unmedicated patients with Parkinson's disease received sub-threshold 5-Hz repetitive transcranial magnetic stimulation (rTMS) over the primary motor hand area (M1(HAND)) contralaterally to the more affected upper limb. Compared to a midfrontal sham-rTMS, real-rTMS over M1(HAND) was associated with a significant de...

    journal_title：Journal of the neurological sciences

    pub_type： 临床试验,杂志文章

    doi：10.1016/s0022-510x(00)00370-1

    authors： Siebner HR,Rossmeier C,Mentschel C,Peinemann A,Conrad B

    更新日期：2000-09-15 00:00:00