Short-term motor improvement after sub-threshold 5-Hz repetitive transcranial magnetic stimulation of the primary motor hand area in Parkinson's disease.

Abstract:

:Ten unmedicated patients with Parkinson's disease received sub-threshold 5-Hz repetitive transcranial magnetic stimulation (rTMS) over the primary motor hand area (M1(HAND)) contralaterally to the more affected upper limb. Compared to a midfrontal sham-rTMS, real-rTMS over M1(HAND) was associated with a significant decrease in the global motor UPDRS score 1 h after the cessation of rTMS. This was mainly due to a clinical improvement in the arm contralaterally to the stimulated M1(HAND). These preliminary data suggest that focal rTMS of M1(HAND) may have a therapeutic potential in PD.

journal_name

J Neurol Sci

authors

Siebner HR,Rossmeier C,Mentschel C,Peinemann A,Conrad B

doi

10.1016/s0022-510x(00)00370-1

subject

Has Abstract

pub_date

2000-09-15 00:00:00

pages

91-4

issue

2

eissn

0022-510X

issn

1878-5883

pii

S0022-510X(00)00370-1

journal_volume

178

pub_type

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