Cyclic Vomiting Syndrome in Infants and Children: A Clinical Follow-Up Study.

abstract：BACKGROUND:No therapies have been formally approved by the Food and Drug Administration for use in pediatric multiple sclerosis, a rare disease. OBJECTIVE:We evaluated the safety, efficacy, and pharmacokinetics of dimethyl fumarate in pediatric patients with multiple sclerosis. METHODS:FOCUS, a phase 2, multicenter s...

journal_title：Pediatric neurology

authors： Alroughani R,Das R,Penner N,Pultz J,Taylor C,Eraly S

更新日期：2018-06-01 00:00:00

abstract：:Stimulant therapy is usually contraindicated in patients with movement disorders such as tics or chorea. A young boy is reported who had benign hereditary chorea and attention deficit disorder, whose chorea, handwriting, and independent ambulation paradoxically improved with methylphenidate treatment. ...

journal_title：Pediatric neurology

authors： Friederich RL

更新日期：1996-05-01 00:00:00

abstract：:A young child with Hallervorden-Spatz syndrome is presented. She was well until 8 years of age when she lost interest in activities and her school performance declined. At age 11 years, she began having episodes of blepharospasm, accompanied by bilateral ptosis and occasional episodes of oculogyric crisis. By age 12 y...

journal_title：Pediatric neurology

authors： Zupanc ML,Chun RW,Gilbert-Barness EF

更新日期：1990-09-01 00:00:00

abstract：BACKGROUND:Electrographic status epilepticus in slow sleep or continuous spike and waves during slow-wave sleep is an epileptic encephalopathy characterized by seizures, neurocognitive regression, and significant activation of epileptiform discharges during nonrapid eye movement sleep. There is no consensus on the diag...

journal_title：Pediatric neurology

authors： Carosella CM,Greiner HM,Byars AW,Arthur TM,Leach JL,Turner M,Holland KD,Mangano FT,Arya R

更新日期：2016-07-01 00:00:00

abstract：:Proteolipid protein (PLP) is the major myelin protein of the central nervous system and is widely believed to play an important structural role in maintaining the myelin compaction. We have studied the early developmental changes of PLP with immunohistochemical methods. Our data demonstrate for the first time a compar...

journal_title：Pediatric neurology

authors： Iai M,Yamamura T,Takashima S

更新日期：1997-10-01 00:00:00

abstract：BACKGROUND:ATP1A3 mutations have now been recognized in infants and children presenting with a diverse group of neurological phenotypes, including Rapid-onset Dystonia-Parkinsonism (RDP), Alternating Hemiplegia of Childhood (AHC), and most recently, Cerebellar ataxia, Areflexia, Pes cavus, Optic atrophy, and Sensorineu...

journal_title：Pediatric neurology

authors： Sweney MT,Newcomb TM,Swoboda KJ

更新日期：2015-01-01 00:00:00

abstract：:This report describes two patients, a father and son, with autosomal dominant Emery-Dreifuss muscular dystrophy. Although the father had the common phenotype, the son had a severe phenotype including early onset of weakness and fatal cardiomyopathy in childhood. Among the patients with severe phenotype of autosomal do...

journal_title：Pediatric neurology

authors： Higuchi Y,Hongou M,Ozawa K,Kokawa H,Masaki M

更新日期：2005-05-01 00:00:00

abstract：:Oxcarbazepine, a carbamazepine analog, was approved for use as an antiepileptic agent in the United States in 2000. A search of the United States Food and Drug Administration's Adverse Event Reporting System identified nine cases of oxcarbazepine-associated angioedema in pediatric patients aged 16 years and younger. W...

journal_title：Pediatric neurology

authors： Knudsen JF,Flowers CM,Kortepeter C,Awaad Y

更新日期：2007-08-01 00:00:00

abstract：:Eleven children, 4-48 months old, with congenital cyanotic heart defects developed choreoathetoid movements 2-12 days after cardiac surgery with hypothermia and extracorporeal circulation (ECC). The abnormal movements mainly involved the limbs, facial musculature, and tongue, leading to a severe dysphagia. The symptom...

journal_title：Pediatric neurology

authors： Gherpelli JL,Azeka E,Riso A,Atik E,Ebaid M,Barbero-Marcial M

更新日期：1998-08-01 00:00:00

abstract：:Ninety term neonates with hyperbilirubinemia were studied with brainstem auditory evoked response to clarify the ototoxic effect of hyperbilirubinemia, and detect any differences in ototoxic effect between different levels of total serum bilirubin. The response threshold in these neonates was significantly elevated (P...

journal_title：Pediatric neurology

authors： Jiang ZD,Chen C,Liu TT,Wilkinson AR

更新日期：2007-07-01 00:00:00

abstract：:The clinical course of anti-muscle specific kinase-positive myasthenia in children has been little reported. Described here is the case of an 8 year-old boy who presented with ptosis and generalized weakness, which resolved within 1 month without any immunomodulatory treatment. This spontaneous remission lasted 6 year...

journal_title：Pediatric neurology

authors： Anlar B,Yilmaz V,Saruhan-Direskeneli G

更新日期：2009-06-01 00:00:00

abstract：:Case reports of four patients with therapy-resistant lesional partial epilepsies and additional foci of benign epileptic discharges of childhood, in addition to the usual electroencephalogram (EEG) changes, are presented. A family history of epileptic or febrile seizures in childhood was reported in all four patients....

journal_title：Pediatric neurology

authors： Degen R,Holthausen H,Pieper T,Tuxhorn I,Wolf P

更新日期：1999-05-01 00:00:00

abstract：:Mitochondrial encephalopathies may be caused by mutations in the respiratory chain complex I subunit genes. Described here are the cases of two pediatric patients who presented with MELAS-like calcarine lesions in addition to novel, bilateral rolandic lesions and epilepsia partialis continua, secondary to MT-ND3 mutat...

journal_title：Pediatric neurology

authors： Werner KG,Morel CF,Kirton A,Benseler SM,Shoffner JM,Addis JB,Robinson BH,Burrowes DM,Blaser SI,Epstein LG,Feigenbaum AS

更新日期：2009-07-01 00:00:00

abstract：:An adolescent girl with systemic lupus erythematosus presented with selective brainstem dysfunction as the initial sign of central nervous system involvement. Although computed tomography was initially normal, magnetic resonance imaging demonstrated multiple, large brainstem lesions. Serial magnetic resonance imaging,...

journal_title：Pediatric neurology

authors： McAbee GN,Barasch ES

更新日期：1990-05-01 00:00:00

abstract：:Sturge-Weber syndrome without facial nevus is rare. Twenty-four cases were previously reported. Although hypomelanosis of Ito is a relatively common disorder, there was only one previous case in association with Sturge-Weber syndrome. We describe an 11-year-old boy with Sturge-Weber syndrome without facial nevus, coex...

journal_title：Pediatric neurology

authors： Değerliyurt A,Kantar A,Ceylaner S,Aysun S

更新日期：2009-05-01 00:00:00

abstract：:We investigated the clinical characteristics of children with continuous spike waves during slow-wave sleep syndrome and their treatment response to levetiracetam. Five boys and one girl, diagnosed with epilepsy with continuous spike waves during slow-wave sleep syndrome, were enrolled. Their clinical characteristics,...

journal_title：Pediatric neurology

authors： Wang SB,Weng WC,Fan PC,Lee WT

更新日期：2008-08-01 00:00:00

abstract：:Neurophysiologic intraoperative monitoring, using somatosensory, brainstem auditory, and visual evoked potentials, transcranial electric motor stimulation, and electromyography, is typically used during complex surgeries involving the motor and sensory cortex, brainstem, cranial nerves, spinal cord, nerve root, periph...

journal_title：Pediatric neurology

authors： Galloway GM,Zamel K

更新日期：2011-03-01 00:00:00

abstract：:The use of lipid-lowering statins has been associated with raised serum muscle enzymes and, occasionally, with rhabdomyolysis, especially in patients with pre-existing metabolic myopathies. The A3243G mutation is one of the most common mutations associated with mitochondrial disorders. A teenager harboring the A3243G ...

journal_title：Pediatric neurology

authors： Tay SK,Dimauro S,Pang AY,Lai PS,Yap HK

更新日期：2008-12-01 00:00:00

abstract：:Risk factors for mortality of young children with cerebral palsy were studied using a sample of 12,709 children aged 0.5-3.5 years with cerebral palsy who had received services from the State of California between 1980 and 1995. The most powerful prognostic factors for survival were simple functional items: mobility a...

journal_title：Pediatric neurology

authors： Strauss DJ,Shavelle RM,Anderson TW

更新日期：1998-02-01 00:00:00

abstract：:Carpal tunnel syndrome, although rare, is known to occur in children mainly because of genetic or metabolic disorders. The clinical findings are variable and include symptoms of burning pain, tingling, numbness, and weakness or atrophy in the hands of the patients. It is usually diagnosed by demonstration of prolonged...

journal_title：Pediatric neurology

authors： Unal O,Ozçakar L,Cetin A,Kaymak B

更新日期：2003-10-01 00:00:00

abstract：:The mechanisms of death and neurologic sequelae in African children with cerebral malaria are undetermined. Because pathologic features are confined to the cerebral vasculature, perturbations in cerebral hemodynamics may be responsible. We compared the transcranial Doppler findings in 50 children with cerebral malaria...

journal_title：Pediatric neurology

authors： Newton CR,Marsh K,Peshu N,Kirkham FJ

更新日期：1996-07-01 00:00:00

abstract：:A 13-year, 6-month-old female was evaluated for subacute onset of left-sided hemichorea/hemiballismus, with an old, right parietal, cortical, and subcortical stroke as the presumed cause. Treatment with gabapentin was initiated, with good results at 6-month follow-up. Discussion of the differential diagnosis and evalu...

journal_title：Pediatric neurology

authors： Kothare SV,Pollack P,Kulberg AG,Ravin PD

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Ring chromosome 20 is a genetic disorder characterized by intractable epilepsy, behavioral problems, and cognitive deficit. The potassium channel-coding gene KCNQ2 is localized at the locus q13.3 on the chromosome 20, the most common site where the ring occurs. Ezogabine is the first potassium channel opener...

journal_title：Pediatric neurology

authors： Walleigh DJ,Legido A,Valencia I

更新日期：2013-11-01 00:00:00

abstract：:We describe eight cases of pediatric patients whose neuroimages performed after seizures revealed abnormalities that were compatible with edema surrounding calcified lesions and which disappeared in subsequent examinations. ...

journal_title：Pediatric neurology

authors： Antoniuk SA,Bruck I,Dos Santos LH,Pintarelli VL,Navolar FB,Brackmann PC Jr,de Morais RL

更新日期：2001-10-01 00:00:00

abstract：:A neuropathologic study was undertaken to examine associated brain damage in patients with fetal and neonatal posthemorrhagic hydrocephalus (PHH). In PHH the association of periventricular leukomalacia and pontosubicular necrosis was not increased, but that of cerebellar subarachnoid hemorrhage and olivo-cerebellar pa...

journal_title：Pediatric neurology

authors： Fukumizu M,Takashima S,Becker LE

更新日期：1995-10-01 00:00:00

abstract：:Mild encephalopathy with reversible splenial lesions has mainly been associated with influenza A and B virus infection. Patients present with neurologic symptoms 1 to 3 days after a prodromal illness and recover completely within a few days. Magnetic resonance imaging typically shows reversible lesions with reduced di...

journal_title：Pediatric neurology

authors： Abenhaim Halpern L,Agyeman P,Steinlin M,El-Koussy M,Grunt S

更新日期：2013-03-01 00:00:00

abstract：:Miller-Dieker syndrome (MDS) is a prototype of brain malformations characterized by abnormal neuronal migration. To clarify the pathomechanisms underlying these anomalies, we performed immunohistochemical studies using specific antibodies against the protein product of LIS-1, the candidate gene responsible for the MDS...

journal_title：Pediatric neurology

authors： Isumi H,Takashima S,Kakita A,Yamada M,Ikeda K,Mizuguchi M

更新日期：1997-01-01 00:00:00

abstract：:Nocturnal frontal-lobe epilepsy is characterized by paroxysmal arousals, motor seizures with dystonic or hyperkinetic features, and episodic nocturnal wanderings. Carbamazepine is effective for seizure control in some of these patients, but seizures may be refractory to multiple antiepileptic drugs. We report on eight...

journal_title：Pediatric neurology

authors： Raju GP,Sarco DP,Poduri A,Riviello JJ,Bergin AM,Takeoka M

更新日期：2007-11-01 00:00:00

abstract：:An 8-year-old boy was diagnosed with autism, along with development delay, seizures, and hypoplastic corpus callosum. His karyotype was 47, XY, +mar.ish (15) (D15Z1+, SNRPN+, GABRB3+, PML-(de novo?). The supernumerary marker chromosome 15 with euchromatin was monosatellited and monocentric. Although autism, seizures, ...

journal_title：Pediatric neurology

authors： Jovanović-Privrodski JD,Kavecan II,Obrenović MR,Buonadonna LA,Bukvić NM

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND:Human cytomegalovirus, a major cause of permanent neurodevelopmental disability in children, frequently produces intracranial abnormalities, including calcifications and polymicrogyria, in infants with congenital cytomegalovirus infections. This report describes the features of cerebral cortical clefting, in...

journal_title：Pediatric neurology

authors： White AL,Hedlund GL,Bale JF Jr

更新日期：2014-03-01 00:00:00