Mild encephalopathy with splenial lesion and parainfluenza virus infection.

abstract：OBJECTIVE:A single-center, single-blind, parallel-group, randomized clinical trial was performed to test the null hypothesis that adrenocorticotropic hormone is not superior to high-dose prednisolone for treatment of newly diagnosed West syndrome. METHODS:Newly diagnosed infants with West syndrome were randomized to r...

journal_title：Pediatric neurology

authors： Wanigasinghe J,Arambepola C,Sri Ranganathan S,Sumanasena S,Attanapola G

更新日期：2015-09-01 00:00:00

abstract：:l-2 hydroxyglutaric aciduria is a rare, autosomal recessively inherited metabolic disorder of organic acid metabolism. A 5-year-old boy presented with eyelid myoclonia with absences that proved difficult to control with first-line anticonvulsants. An electroencephalogram produced profoundly abnormal results, with gene...

journal_title：Pediatric neurology

authors： Mete A,Isikay S,Sirikci A,Ozkur A,Bayram M

更新日期：2012-03-01 00:00:00

abstract：:A wide cavum septum pellucidum defined as a separation of greater than 1 cm of the leaves occurs uncommonly. Nine children with wide cavum septum pellucidum were studied; 8 were abnormal. Observed abnormalities included cognitive impairment (8), seizures (4), hypoplasia of the corpus callosum (4), optic nerve hypoplas...

journal_title：Pediatric neurology

authors： Bodensteiner JB,Schaefer GB

更新日期：1990-11-01 00:00:00

abstract：:Leigh syndrome, caused by dysfunction in mitochondrial energy metabolism, is an inherited, heterogeneous, and progressive neurodegenerative disorder of infancy and childhood. From 1983 to August 2006, 14 cases diagnosed with Leigh syndrome were studied in terms of characteristic neuroimaging findings and abnormal mito...

journal_title：Pediatric neurology

authors： Lee HF,Tsai CR,Chi CS,Lee HJ,Chen CC

更新日期：2009-02-01 00:00:00

abstract：OBJECTIVE:To investigate clinical risk factors for acute magnetic resonance imaging (MRI) abnormalities in patients with benign convulsions with mild gastroenteritis or benign infantile epilepsy. STUDY DESIGN:We investigated clinical and diffusion-weighted imaging findings in 32 patients with benign convulsions with m...

journal_title：Pediatric neurology

authors： Ogawa C,Kidokoro H,Ishihara N,Tsuji T,Kurahashi H,Hattori A,Suzuki M,Ogaya S,Ito Y,Fukasawa T,Kubota T,Okumura A,Saitoh S,Natsume J

更新日期：2020-08-01 00:00:00

abstract：:Chronic oral VP-16 (etoposide) is a chemotherapy regimen with a wide application in oncology and documented efficacy against germ cell tumors, lymphomas, Kaposi's sarcoma, and primary brain tumors. This study was performed to assess the toxicity and activity of chronic oral etoposide in the management of children with...

journal_title：Pediatric neurology

authors： Chamberlain MC

更新日期：2001-02-01 00:00:00

abstract：:Ketoacidosis is one of the common complications of Type I insulin-dependent diabetes mellitus. Several neurologic (cerebral) deficiencies have been associated with diabetic ketoacidosis, including cerebral edema with increased intracranial pressure resulting in coma; partial and generalized seizures; and cerebrovascul...

journal_title：Pediatric neurology

authors： Atluru VL

更新日期：1986-05-01 00:00:00

abstract：:Adenylosuccinate lyase deficiency is an autosomal recessive disorder of purine metabolism resulting from mutations in the ADSL gene on chromosome subband 22q13.1 and associated with a wide range of clinical manifestations. Although there is currently no effective treatment of ADSL deficiency, recognition of the condit...

journal_title：Pediatric neurology

authors： Lundy CT,Jungbluth H,Pohl KR,Siddiqui A,Marinaki AM,Mundy H,Champion MP

更新日期：2010-11-01 00:00:00

abstract：:We sought to distinguish patients testing positive for human herpesvirus 6 from those testing negative, based on clinical features and magnetic resonance images. Sixteen immunosuppresed patients were tested by polymerase chain reaction for human herpes virus 6 DNA in cerebrospinal fluid (nine positive results). Medica...

journal_title：Pediatric neurology

authors： Provenzale JM,van Landingham K,White LE

更新日期：2010-01-01 00:00:00

abstract：:Periventricular hyperintensity was detected using long repetition and echo time on spin-echo magnetic resonance imaging in 24 of 32 children with birth weights less than 2,500 gm. Functionally, 11 children were normal, 6 mildly handicapped, 7 moderately handicapped, and 8 severely handicapped. The functional handicaps...

journal_title：Pediatric neurology

authors： Sugita K,Takeuchi A,Iai M,Tanabe Y

更新日期：1989-11-01 00:00:00

abstract：:This report describes a case of West Nile virus meningoencephalitis in a previously healthy adolescent. Clinical features included fever, altered mental status, and speech difficulty, with subsequent hyperesthesia, ataxia, and motor weakness, all of which eventually resolved completely. Magnetic resonance imaging was ...

journal_title：Pediatric neurology

authors： DeBiasi RL,Parsons JA,Grabert BE

更新日期：2005-09-01 00:00:00

abstract：:Evaluation of a 7-month-old girl with developmental delay and intractable seizures revealed hemispheric asymmetry and an enlarged right cerebral hemisphere. Because of a history of seizures refractory to medical therapy, she was admitted for right hemispherectomy, but died of complications of surgery. Postmortem brain...

journal_title：Pediatric neurology

authors： Jahan R,Mischel PS,Curran JG,Peacock WJ,Shields DW,Vinters HV

更新日期：1997-11-01 00:00:00

abstract：:The aim of this study was to define the risk ratios of the late-infancy magnetic resonance imaging pattern for long-term outcome in term infants with perinatal asphyxia. We evaluated 65 term infants with perinatal asphyxia and performed magnetic resonance imaging examinations between 4-12 months of age. Magnetic reson...

journal_title：Pediatric neurology

authors： Tekgul H,Serdaroglu G,Yalman O,Tutuncuoglu S

更新日期：2004-07-01 00:00:00

abstract：:Cerebral creatine transporter deficiency, attributable to mutations in the SLC6A8 gene, causes X-linked mental retardation, language delay, epilepsy, and autistic features. In contrast with creatine synthesis defects, the vast majority of patients with SLC6A8 deficiency do not respond to treatment. We describe a Portu...

journal_title：Pediatric neurology

authors： Garcia P,Rodrigues F,Valongo C,Salomons GS,Diogo L

更新日期：2012-01-01 00:00:00

abstract：:Pseudoaneurysm of the internal carotid artery is an extremely uncommon complication of pediatric deep neck space infections in the postantibiotic era, and poses a diagnostic challenge to clinicians. Early recognition and aggressive management are essential to prevent mortality and serious morbidity. We describe a pseu...

journal_title：Pediatric neurology

authors： Sankararaman S,Velayuthan S,Gonzalez-Toledo E

更新日期：2012-10-01 00:00:00

abstract：:A male with developmental dysphasia is documented with fine motor dysfunction whose improvement in expressive language was associated with increased cerebellar perfusion, as detected by serial N-isopropyl-p-[iodine-123] iodoamphetamine single photon emission computed tomography (SPECT). His expressive language has bee...

journal_title：Pediatric neurology

authors： Oki J,Takahashi S,Miyamoto A,Tachibana Y

更新日期：1999-10-01 00:00:00

abstract：:We present a 2-year-old patient who showed progressive widespread white-matter abnormalities on magnetic resonance imaging 1 month after viral encephalitis, despite her good clinical recovery. These lesions on magnetic resonance imaging had not responded to therapies commonly used to treat secondary immune-mediated de...

journal_title：Pediatric neurology

authors： Awaya T,Kato T,Shibata M,Yamanaka Y,Nakahata T

更新日期：2008-03-01 00:00:00

abstract：:Traumatic spinal epidural hematoma (TSEH) is rare in children. Only three cases of TSEH were documented in the pediatric literature. This clinical note presents an infant with TSEH but no risk factors. Without magnetic resonance imaging examination, children with TSEH and minor symptoms may be missed and under reporte...

journal_title：Pediatric neurology

authors： Alva NS

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND:Autopsy studies in Rasmussen encephalitis reveal areas of sparing within the affected hemisphere. Clinical progression and inflammation are milder with an older onset. We sought to demonstrate radiological corroboration for these patterns. METHODS:In our retrospective study, 38 cases were dichotomized into ...

journal_title：Pediatric neurology

authors： Benjamin RN,Thomas M,Muthusamy K,Yoganathan S,Mathew V,Chacko AG,Prabhu K,Chacko G

更新日期：2020-11-01 00:00:00

abstract：:Cloxazolam has been used mainly as an anxiolytic agent. The present study was designed to evaluate the effectiveness of cloxazolam as an add-on antiepileptic drug in patients with intractable epilepsy. A total of 32 patients with intractable epilepsy were treated with cloxazolam: 13 with generalized epilepsy, 15 with ...

journal_title：Pediatric neurology

authors： Kimura N,Fujii T,Miyajima T,Kumada T,Mikuni T,Ito M

更新日期：2010-12-01 00:00:00

abstract：:Two siblings presented with identical features of progressive peripheral paralysis of the lower motor neuron type, pyramidal signs, cranial nerve palsy which included external ocular palsy and deafness, and internal ocular palsy; both died before 1 year of age. Pathologic examination of the central nervous system in b...

journal_title：Pediatric neurology

authors： Hamano K,Tsukamoto H,Yazawa T,Yoshimura M,Takita H

更新日期：1994-06-01 00:00:00

abstract：:Opsoclonus is a rare childhood ocular motility disorder characterized by irregular, chaotic, involuntary bursts of high amplitude, back-and-forth oscillations of the eyes,without pause intervals. Although this disorder is associated with neuroblastoma and other neural crest tumors, as well as with other neurologic abn...

journal_title：Pediatric neurology

authors： Morad Y,Benyamini OG,Avni I

更新日期：2004-10-01 00:00:00

abstract：:To clarify reflex profiles in the first year of life in connection with categories of neurologic abnormality, eight primitive reflexes (i.e., the palmar grasp reflex, the plantar grasp reflex, the Galant response, the asymmetric tonic neck reflex, the suprapubic extensor reflex, the crossed extensor reflex, the Rossol...

journal_title：Pediatric neurology

authors： Zafeiriou DI,Tsikoulas IG,Kremenopoulos GM

更新日期：1995-09-01 00:00:00

abstract：BACKGROUND:Corpus callosum atrophy has been associated with cognitive and motor deficits in elderly people. However, the role of the corpus callosum in infant development is unclear. The aim of this study was to assess the impact of corpus callosum size on motor development in infants. METHODS:We investigated cerebral...

journal_title：Pediatric neurology

authors： Chang CL,Hung KL,Yang YC,Ho CS,Chiu NC

更新日期：2015-02-01 00:00:00

abstract：:We report the clinical features and the muscle pathology in 2 patients with congenital muscular dystrophy (CMD) secondary to merosin deficiency and in 2 patients with sarcoglycan (adhalin) deficiency. Electron microscopic examination revealed sarcolemmal defects in non-necrotic muscle fibers in all cases. These pathol...

journal_title：Pediatric neurology

authors： Fadic R,Waclawik AJ,Lewandoski PJ,Lotz BP

更新日期：1997-01-01 00:00:00

abstract：:We investigated the clinical characteristics of children with continuous spike waves during slow-wave sleep syndrome and their treatment response to levetiracetam. Five boys and one girl, diagnosed with epilepsy with continuous spike waves during slow-wave sleep syndrome, were enrolled. Their clinical characteristics,...

journal_title：Pediatric neurology

authors： Wang SB,Weng WC,Fan PC,Lee WT

更新日期：2008-08-01 00:00:00

abstract：:Alagille syndrome is associated with various ocular abnormalities, including pseudopapilledema or optic disk edema due to increased intracranial pressure. Several mechanisms have been proposed to explain the mechanism of intracranial hypertension in Alagille syndrome. Craniosynostosis is an unusual but significant cau...

journal_title：Pediatric neurology

authors： Yilmaz S,Turhan T,Mutluer S,Aydogdu S

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Rett syndrome is characterized by psychomotor regression during early childhood, autistic-like behaviors, and aberrant breathing patterns. Dysfunction of the serotonergic system has been postulated to play a role in the pathophysiology of these symptoms. PATIENT DESCRIPTION:We present an 11-year-old girl wi...

journal_title：Pediatric neurology

authors： Ohno K,Saito Y,Ueda R,Togawa M,Ohmae T,Matsuda E,Fujiyama M,Maegaki Y

更新日期：2016-07-01 00:00:00

abstract：:A case of alternating hemiplegia of childhood is reported. Tonic fits and generalized tonic-clonic seizures developed during her infancy. Frequent twitching and apneic seizures appeared at 16 years of age. Zonisamide transiently suppressed the tonic, twitching and apneic seizures, as well as the facial and neck dyston...

journal_title：Pediatric neurology

authors： Saito Y,Sakuragawa N,Sasaki M,Sugai K,Hashimoto T

更新日期：1998-07-01 00:00:00

abstract：:Tumefactive demyelinating lesions may be misdiagnosed as brain neoplasms or abscesses. In this paper, we present four cases of pediatric tumefactive demyelination. Twelve cases of pediatric tumefactive demyelination previously reported in the English literature are also summarized. We describe the neuroimaging charact...

journal_title：Pediatric neurology

authors： McAdam LC,Blaser SI,Banwell BL

更新日期：2002-01-01 00:00:00