Dietary consumption of advanced glycation end products and risk of metabolic syndrome.

Abstract:

:Metabolic syndrome (MetS) is a complex disorder which has become one of the major public health challenges worldwide. This study was conducted to evaluate the association between dietary advanced glycation end products (AGEs) and risk of MetS and its components. This cross-sectional study was conducted in a representative sample of 5848 adults, aged 19-70 years. Daily consumption of carboxymethyl lysine, a major type of AGEs, was determined using a validated semi-quantitative food frequency questionnaire. Across increasing trend of AGEs consumption, the percentage of fat intake increased and that of carbohydrate significantly decreased (p < 0.001). Subjects in the highest (>10,506 kU/d) compared to the lowest (<6673 kU/d) quartile category of AGEs had higher risk of abdominal obesity (OR: 1.19, 95% CI: 1.01-1.39) and hypertriglyceridemia (OR: 1.26, 95% CI: 1.07-1.49). Therefore, recommendation on restriction of AGEs intake could be a practical approach to prevent metabolic abnormalities.

journal_name

Int J Food Sci Nutr

authors

Angoorani P,Ejtahed HS,Mirmiran P,Mirzaei S,Azizi F

doi

10.3109/09637486.2015.1137889

subject

Has Abstract

pub_date

2016-01-01 00:00:00

pages

170-6

issue

2

eissn

0963-7486

issn

1465-3478

journal_volume

67

pub_type

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