Abstract：
INTRODUCTION:This review presents an overview of descriptive knowledge on human embryonic cardiovascular physiology mostly based on noninvasive assessment by Doppler ultrasonography. Our objective was to identify and analyze published studies on embryonic cardiovascular function, and summarize available knowledge in this field. MATERIAL AND METHODS:Citations related to human embryonic cardiovascular function were searched in PubMed, EMBASE, CINAHL and Web of Science using keywords and MeSH terms without any time limitation. The search was restricted to English language articles. Abstracts were screened and full texts of relevant articles were obtained. All articles that reported on physiological aspects of human embryonic cardiovascular function were included. Studies reporting on cardiovascular function after 10 weeks of gestation were excluded. Data were synthesized and presented narratively. RESULTS:We identified 10 studies that had evaluated cardiovascular function and/or hemodynamics in human embryos at ≤10 weeks of gestation. All of these reported only certain aspects of embryonic cardiovascular function. Embryonic heart rate is associated significantly with gestational age and increases from 6 to 10 weeks of gestation. Cardiac inflow is monophasic during the embryonic period and atria appear to generate higher force during contraction compared with ventricles. Both ventricular inflow and outflow velocities increase with advancing gestation, whereas the Tei index decreases significantly. During the embryonic period, placental blood flow increases with gestation, but absent umbilical artery diastolic flow and umbilical venous pulsations are normal phenomena. CONCLUSION:There are important differences in normal cardiovascular function between the embryonic and fetal stages of human in utero development.
journal_name
Acta Obstet Gynecol Scandjournal_title
Acta obstetricia et gynecologica Scandinavicaauthors
Acharya G,Gui Y,Cnota W,Huhta J,Wloch Adoi
10.1111/aogs.12860subject
Has Abstractpub_date
2016-06-01 00:00:00pages
621-8issue
6eissn
0001-6349issn
1600-0412journal_volume
95pub_type
评论,杂志文章,评审abstract：:A rare case of hepatocellular carcinoma in a 31-year-old woman is reported. The diagnosis was made at 16 weeks of pregnancy when very high levels of alpha-feto-protein were found upon routine examination. The pregnancy was terminated and cytostatic therapy was given. The patient died one year later. ...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016349109006217
更新日期：1991-01-01 00:00:00
abstract：OBJECTIVE:To compare the neonatal outcome after a trial of labor (TOL) with that after an elective cesarean section (CS) following one previous cesarean delivery, considering the indication for the first CS. DESIGN:Population-based cohort study. SETTING:Sweden. POPULATION:Women with their first two deliveries betwee...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.1111/aogs.12202
更新日期：2013-10-01 00:00:00
abstract：:This study was performed to investigate the efficacy of oral mifepristone and vaginal gemeprost for termination of early pregnancy. Eighty women requesting first trimester abortion and with amenorrhea of less than 56 days were included. Gestational age was confirmed with ultrasonography. Mifepristone was administered ...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016349309013347
更新日期：1993-01-01 00:00:00
abstract：BACKGROUND:It is well known that a large proportion of first-trimester spontaneous abortions is caused by chromosomal disorders. The present study represents a unique material and the success rate of the karyotyping was high. METHODS:Chromosomal analysis from chorionic villus sampling of 259 of 304 consecutive first-t...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.0001-6349.2005.00882.x
更新日期：2005-11-01 00:00:00
abstract：OBJECTIVE:To investigate risks of torsion and malignancy by adnexal mass size during pregnancy. DESIGN:Retrospective review of medical records. SETTING:General university hospital and healthcare center. POPULATION:Four hundred and seventy women who underwent surgery for adnexal masses during pregnancy between 2002 a...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0412.2011.01070.x
更新日期：2011-04-01 00:00:00
abstract：AIM:To assess the current prescribing pattern for 15,756 primiparae before, during, and after their pregnancies with reference to fetal and neonatal risk. METHOD:A prescription database study with linkage to The Danish Medical Birth Registry from 1991 to 1996. The drug subsidy system in Danish retail pharmacies, made ...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.1034/j.1600-0412.1999.780805.x
更新日期：1999-09-01 00:00:00
abstract：:The therapeutic value of 2-Br-alpha-ergocryptine for the suppression of puerperal lactation was studied in 30 normal women; 16 received the drug, 14 were controls. In six women plasma levels of FSH, oestradiol and alpha-lactalbulmin were measured in labour and in the early puerperium. Brom-ergocryptine was found effec...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 临床试验,杂志文章
doi：10.3109/00016347709158357
更新日期：1977-01-01 00:00:00
abstract：:In 2108 pregnant women, external abdominal measurements were correlated to the weight of the newborn child. The product of girth and uterine height was more closely correlated to the infant weight than were any of these maternal variables alone or in other combinations, but the accuracy of this method was almost as lo...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016348409154656
更新日期：1984-01-01 00:00:00
abstract：OBJECTIVE:Currently, no prospective study supports or refutes the value of secondary cytoreductive surgery in patients with ovarian cancer. We therefore reviewed the surgical data of patients who underwent second-look laparotomy (SLL) with or without secondary cytoreductive surgery at our department. METHODS:Analysis ...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：
更新日期：2001-05-01 00:00:00
abstract：:The long-term consequences and complications of tubal sterilization were studied. Six years after surgery, information was obtained from 208 of 216 women. Five had been pregnant. Eight had been bothered by their scars for 2 years or more. The majority reported improved conjugal relations and a positive impact on marri...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016348409156708
更新日期：1984-01-01 00:00:00
abstract：OBJECTIVES:To examine the association between placenta previa with maternal race and its variations by country of origin among Asian women. STUDY DESIGN:Retrospective cohort study. METHODS:We analyzed data from a population-based retrospective cohort study of 16,751,627 pregnancies in the US. The data were derived fr...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.1080/00016340802071037
更新日期：2008-01-01 00:00:00
abstract：:To assess the capacity of the corpus luteum to secrete steroid hormones and relaxin during spontaneous abortion, human chorionic gonadotropin (hCG), progesterone, 17 alpha-hydroxyprogesterone (17-OHP) and relaxin concentrations were determined in serum samples obtained from 16 spontaneously aborting first-trimester pa...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016348809029857
更新日期：1988-01-01 00:00:00
abstract：:In 64 pregnant women admitted to hospital because of threatened abortion the prognostic value of estradiol-17-beta, estriol and human placental lactogen (HPL) in serum was examined. The hormones were determined by radioimmunoassay. Blood samples were taken at regular intervals during admission to hospital and subseque...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016347909154597
更新日期：1979-01-01 00:00:00
abstract：BACKGROUND:The Term Breech Trial has considerably increased the number of cesareans. External cephalic version (ECV) might be an effective method of lowering the rate of cesareans; its efficacy has been well established. However, although in the absence of anesthesia the risks are thought to be low, most studies have u...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章,评审
doi：10.1111/j.0001-6349.2004.00347.x
更新日期：2004-06-01 00:00:00
abstract：OBJECTIVE:To provide descriptive statistics on hysterectomy for benign gynecological conditions in the Netherlands and to analyze regional and temporal variations in hysterectomy rates and surgical routes. DESIGN:Retrospective cohort study. SETTING:Dutch hospitals. POPULATION:All women with a hysterectomy for benign...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0412.2011.01309.x
更新日期：2012-02-01 00:00:00
abstract：OBJECTIVE:To compare in controlled cardiovascular autonomic function tests the effects of hormone therapy (HT) on heart rate variability (HRV) responses in postmenopausal women with and without pretreatment hot flushes. DESIGN:A randomized placebo-controlled trial. SETTING:Finland, Helsinki University Central Hospita...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章,随机对照试验
doi：10.1111/aogs.12164
更新日期：2013-08-01 00:00:00
abstract：:Puerperal inversion of the uterus is very rare but dramatic and life-threatening. Prompt treatment is necessary. A case is reported and the literature reviewed. ...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章,评审
doi：
更新日期：1992-10-01 00:00:00
abstract：:A cancer registry cohort of 16,704 cases of invasive carcinoma of the uterine cervix and 56,116 cases of in situ carcinomas of the uterine cervix was followed up and second new primary cancers were recorded. The invasive carcinomas contributed 127,118 woman-years at risk and the in situ carcinomas contributed 453,362 ...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016349009006163
更新日期：1990-01-01 00:00:00
abstract：OBJECTIVE:The purpose of this study was to determine the clinical and urodynamic characteristics of women with recurrent urinary incontinence after Burch colposuspension. MATERIAL:Fifty women subjectively complaining of recurrent urinary incontinence (RUI) median 6 years after Burch colposuspension and 52 women with p...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016349709047829
更新日期：1997-05-01 00:00:00
abstract：OBJECTIVE:To assess the role of the placental arterial Doppler examination at 23-24 gestational weeks for predicting adverse perinatal outcome in high-risk pregnancies. DESIGN:Retrospective register study. SETTING:Skåne University Hospital in Malmö. POPULATION:Six hundred and forty-five women with high-risk pregnanc...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.1111/aogs.12488
更新日期：2014-12-01 00:00:00
abstract：:Congenital granular cell myoblastoma of the newborn is a rare tumor. The combination of polyhydramnios caused by obstruction of the infant's mouth by this tumor is extremely rare, and this is the first published report of such a condition. ...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016348609157400
更新日期：1986-01-01 00:00:00
abstract：:Ten postmenopausal women were studied in an attempt to identify the mechanism of action of cyclofenil, a non-steroidal anti-estrogen which has proved to be effective in the climacteric syndrome. A double-blind inter-patient clinical investigation was undertaken, with patients assigned randomly to treatment for 10 days...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.3109/00016348209156597
更新日期：1982-01-01 00:00:00
abstract：OBJECTIVE:To evaluate the efficacy of three different doses of Nestorone progestin administered by implants for relief of pain, as well as bleeding patterns and symptoms in women with endometriosis. DESIGN:An open clinical study without a control group. PATIENTS:Twenty-one women in whom endometriosis was diagnosed an...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：2003-02-01 00:00:00
abstract：BACKGROUND:To determine the influence of hyaluronan and its receptor CD44 in the angiogenesis and invasiveness of intravenous leiomyomatosis (IVL). METHODS:Paraffin-embedded sections from four IVL cases and 10 uterine leiomyoma cases were immunohistochemically stained for CD34, CD44, basic fibroblast growth factor (bF...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.0001-6349.2005.00707.x
更新日期：2005-04-01 00:00:00
abstract：BACKGROUND:External cephalic version (ECV) is accepted as a means of reducing the rate of breech presentation at term. Routine use of tocolysis prior to an ECV has been described to increase its success rate. The study's objective was to evaluate the efficacy of oral nifedipine as a tocolytic agent prior to ECV, and to...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.1080/00016340801996598
更新日期：2008-01-01 00:00:00
abstract：BACKGROUND:There has been a rise in the prevalence of large newborns over a few decades in many parts of the world. There is ample evidence that fetal macrosomia is associated with increased risk of complications both for the mother and the newborn. In current obstetrics, the macrosomic fetus represents a frequent clin...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章,评审
doi：10.1080/00016340801899289
更新日期：2008-01-01 00:00:00
abstract：INTRODUCTION:Post-term pregnancies are associated with greater risks for mother and child. Accurate determination of gestational age is necessary for safe care. Female fetuses have been shown to be smaller than males at the time of second-trimester ultrasound (US) examination, leading to underestimation of their age an...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.1111/aogs.12774
更新日期：2015-12-01 00:00:00
abstract：:The results of 204 cases of regional analgesia by means of continuous epidural block during labour and delivery are reported. The frequency of instrummental intervention using forceps or the vacuum extractor is low, less than 15% for primi- and multi-gravidas combined, although pathological conditions were recognized ...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016347509157101
更新日期：1975-01-01 00:00:00
abstract：BACKGROUND:The aim of this study was to determine the long-term prognosis of fecundity among couples with unexplained infertility and to compare pregnancy course and outcome in spontaneous versus treatment-related pregnancies. METHODS:A prospective follow-up study of 70 couples with a diagnosis of unexplained infertil...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：
更新日期：1998-09-01 00:00:00
abstract：INTRODUCTION:To assess the association between miR-200 family expression and overall survival/progression-free survival in women with ovarian cancer. MATERIAL AND METHODS:A systematic literature search, up to September 2015, in PubMed, EMBASE and Cochrane Library was performed to identify articles that assessed the as...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章,meta分析,评审
doi：10.1111/aogs.12883
更新日期：2016-05-01 00:00:00
