Abstract：
OBJECTIVE:Currently, no prospective study supports or refutes the value of secondary cytoreductive surgery in patients with ovarian cancer. We therefore reviewed the surgical data of patients who underwent second-look laparotomy (SLL) with or without secondary cytoreductive surgery at our department. METHODS:Analysis is based on the data of 179 patients who had FIGO stage II (suboptimally staged), stage III or IV ovarian cancer, who received a platinum-based first-line chemotherapy, who were clinically considered to be tumor-free or had at least a clinically partial response to first-line chemotherapy, and who underwent SLL. In patients with macroscopic tumor the diagnostic SLL was followed by a secondary cytoreductive surgery in order to remove as much tumor as possible. Patients with a positive SLL were given second-line chemotherapy. Survival from SLL until death was considered the primary statistical endpoint. RESULTS:In 78 out of 179 (43.5%) a negative SLL could be confirmed pathologically. Patients with negative findings, with microscopic, and macroscopic disease at SLL had a median survival of 66.6, 57.2, and 19.0 months, respectively (p=0.0001). In patients who underwent a secondary cytoreductive operation and in whom residual tumor was none, less than 2 cm, or more than 2 cm, the median survival was 22.9, 17.8, and 15.5 months, respectively (p=0.325). CONCLUSIONS:The presence of macroscopic tumor at SLL is an adverse prognostic factor whereas the role of secondary cytoreductive surgery at SLL appears to be limited in the routine management of ovarian cancer patients.
journal_name
Acta Obstet Gynecol Scandjournal_title
Acta obstetricia et gynecologica Scandinavicaauthors
Obermair A,Sevelda Psubject
Has Abstractpub_date
2001-05-01 00:00:00pages
432-6issue
5eissn
0001-6349issn
1600-0412pii
aog800510journal_volume
80pub_type
杂志文章abstract：:Low-lying placentas, placenta previa and abnormally invasive placentas are the most frequently occurring placental abnormalities in location and anatomy. These conditions can have serious consequences for mother and fetus mainly due to excessive blood loss before, during or after delivery. The incidence of such abnorm...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.1111/aogs.13834
更新日期：2020-08-01 00:00:00
abstract：OBJECTIVE:To describe the background characteristics of women who gave birth to their first child at an advanced and very advanced maternal age, including their sociodemographic background, social relationships, health behavior, physical and mental health, and reproductive history. DESIGN:Cross-sectional data from the...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0412.2011.01335.x
更新日期：2012-03-01 00:00:00
abstract：BACKGROUND:The purpose of the study was to evaluate the immediate outcome and complications of the tension-free vaginal tape (TVT) and laparoscopic mesh colposuspension (LC) procedures in the treatment of female stress urinary incontinence (SUI). METHODS:One hundred and twenty-eight patients suffering from urodynamica...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：
更新日期：2003-07-01 00:00:00
abstract：:Our purpose was to investigate whether obstetric analgesia, particularly by nitrous oxide, constitutes a risk that the infant might develop amphetamine addiction in later life. Of 200 current amphetamine addicts born between 1945 and 1966 in Stockholm, proportionately more were born at hospitals where pain medication ...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016349809004288
更新日期：1988-01-01 00:00:00
abstract：BACKGROUND:Due to high abortion rates in a low status area in Göteborg, Sweden, a study was performed focused on the pregnancy test. METHOD AND MATERIAL:The aim of the study was to facilitate the accessibility of contraceptive counseling offering immediate and extended family planning advice to women with negative pre...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.1080/j.1600-0412.1998.770313.x
更新日期：1998-03-01 00:00:00
abstract：BACKGROUND:A study was initiated to identify background factors, clinical features and pre-operative scoring systems of importance for future selection of patients suitable for fertility surgery. METHODS:Surgical procedures, background factors and scoring systems for tubal lesions and adnexal adhesions and risk factor...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016349509024450
更新日期：1995-04-01 00:00:00
abstract：OBJECTIVE:To determine the contribution of maternal lipids in predicting large-for-gestational age (LGA) newborns born to women with gestational diabetes mellitus (GDM). DESIGN:Retrospective study. SETTING:Yonsei University Health System, Korea. POPULATION:A total of 104 women diagnosed with GDM between January 2000...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016341003605677
更新日期：2010-05-01 00:00:00
abstract：:Studies on the natural history of endometriosis have demonstrated that the majority of endometriosis implants tend to progress, a finding that indicates eradication of the lesions by medical and/or surgical approaches. Infertility and dysmenorrhea are other indications for medical therapy in this disease. In recent pr...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章,评审
doi：10.3109/00016349309021107
更新日期：1993-07-01 00:00:00
abstract：BACKGROUND:The development of advanced endoscopic instrumentation in recent years has demonstrated the superiority of direct visual examination over radiographic demonstration of various body cavities. Just as laparoscopy has gradually taken a primary role in the surgical investigation of the ovulatory infertile patien...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016349609054692
更新日期：1996-08-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to compare pregnancy and live birth rates in poor responders when transferring one or two embryos. Poor responders were defined as having four or fewer oocytes retrieved in combination with a high dose of gonadotrophins. DESIGN:Retrospective, observational study. SETTING:Reproducti...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0412.2011.01139.x
更新日期：2011-07-01 00:00:00
abstract：:Association between the histidine-rich glycoprotein (HRG) C633T single nucleotide polymorphism (SNP) and recurrent miscarriage was investigated in a case-control study. The cases constituted 187 women with recurrent miscarriage that were compared with 395 controls who had delivered a child and had no history of miscar...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.1111/aogs.12155
更新日期：2013-08-01 00:00:00
abstract：BACKGROUND:Little is published about obstetrical problems after treatment of cervical intraepithelial neoplasia with the C02-laser. The aim of this study was to determine the risk of low birth weight in the subsequent pregnancy after laser conization or vaporization in a follow-up study of women treated for cervical in...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016349609033306
更新日期：1996-02-01 00:00:00
abstract：BACKGROUND:We have reviewed the literature concerning vaginal recurrence in endometrial cancer with emphasis on prognostics and therapeutic results. Compared to the overall outcome of recurrences (11-17 per cent survive more than 3-19 years) the survival rate of strictly vaginal recurrence appears significantly higher ...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章,评审
doi：10.3109/00016349609033275
更新日期：1996-01-01 00:00:00
abstract：BACKGROUND:Unexplained antepartum stillbirth is a common cause of perinatal death, and identifying the fetus at risk is a challenge for obstetric practice. Intrauterine growth restriction (IUGR) is associated with a variety of adverse perinatal outcomes, but reports on its impact on unexplained stillbirths by populatio...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.0001-6349.2004.00602.x
更新日期：2004-09-01 00:00:00
abstract：OBJECTIVE:To evaluate the efficacy of three different doses of Nestorone progestin administered by implants for relief of pain, as well as bleeding patterns and symptoms in women with endometriosis. DESIGN:An open clinical study without a control group. PATIENTS:Twenty-one women in whom endometriosis was diagnosed an...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：2003-02-01 00:00:00
abstract：BACKGROUND:The aim was to evaluate the psychological and physical impact on women submitting to early amniocentesis or chorionic villus sampling and their preferences concerning fetal invasive procedures in a forthcoming pregnancy. METHOD:Fifty-one women undergoing early amniocentesis or chorionic villus sampling at 1...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：2001-06-01 00:00:00
abstract：OBJECTIVE:To analyze compensation claims with neurological sequela or death following alleged birth asphyxia. DESIGN:A cohort study. SETTING:A nationwide study in Norway. SAMPLE:All claims made to The Norwegian System of Compensation to Patients (NPE) concerning sequela related to alleged birth asphyxia, between 199...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.1111/aogs.12276
更新日期：2014-02-01 00:00:00
abstract：OBJECTIVE:To assess the occurrence of spontaneous abortion, comparing two different data sources. To estimate the rate of spontaneous abortion over a 2-year period, and examine potential predictors of the risk for incident spontaneous abortion. METHODS:We used interview data from a population-based prospective cohort ...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.1080/00016340500494887
更新日期：2006-01-01 00:00:00
abstract：:Seventy patients were treated for a subcutaneous abscess in the vulva. In 35 consecutive patients the abscess was treated conventionally with deroofing of the abscess and wet dressings. In the other 35 consecutive patients the abscess was treated by incision, curettage and primary suture under antibiotic cover with a ...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016348609157385
更新日期：1986-01-01 00:00:00
abstract：BACKGROUND:Excessive bleeding is one of the major threats to women at childbirth. The aim of this study was to validate estimation of blood loss during delivery. METHODS:Bleeding was estimated after 29 elective cesarean sections and 26 vaginal deliveries and compared to blood loss measured by extraction of hemoglobin ...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.1080/00016340600985032
更新日期：2006-01-01 00:00:00
abstract：OBJECTIVE:This study aims to evaluate the feasibility and diagnostic validity of the sentinel lymph node technique in detecting inguinal lymph node metastases in patients with invasive squamous cancer of the vulva. DESIGN:Retrospective analysis of the in-house tumor registry. SETTING:Dr. Horst Schmidt Klinik, a terti...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016340903317982
更新日期：2009-01-01 00:00:00
abstract：BACKGROUND:Maternal symptoms such as severe headache, nausea and vomiting, visual disturbances and epigastric pain have been associated with complications in women with preeclampsia. OBJECTIVE:To determine the accuracy of maternal symptoms in predicting complications in women with preeclampsia by systematic review. D...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章,meta分析,评审
doi：10.1111/j.1600-0412.2011.01111.x
更新日期：2011-06-01 00:00:00
abstract：INTRODUCTION:Abnormally invasive placenta is a major cause of maternal morbidity and mortality. The aim of this study was to assess the effectiveness of a standardized operative approach performed by gynecological oncologists in the surgical management of abnormally invasive placenta. MATERIALS AND METHODS:We performe...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.1111/aogs.12768
更新日期：2015-12-01 00:00:00
abstract：OBJECTIVE:To investigate the relation between pelvic floor muscle strength and sexual function among women with higher and lower pelvic floor muscle strength. DESIGN:A cross-sectional study was performed among employees and students of the University. SETTING:Urogynecology department, Federal University of Pampa, Bra...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.1111/aogs.12379
更新日期：2014-05-01 00:00:00
abstract：:Ninety-six cases of ruptured uterus in labor treated in the University Teaching Hospitals, Benghazi, Libya between 1977 and 1980 are reported. An incidence of 1 in 585 deliveries remained unchanged during the period of study. Twenty uterine ruptures occurred in a previously scarred uterus. Rupture of the unscarred ute...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016348509155137
更新日期：1985-01-01 00:00:00
abstract：BACKGROUND:Open multidisciplinary centers were operated in the mid 1990s for victims of sexual assaults in Oslo and Reykjavik. However, in Copenhagen and Helsinki forensic medical examination was only available to victims who reported directly to the police. One of the main aims of this study was to compare the effect ...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.0001-6349.2005.00641.x
更新日期：2005-02-01 00:00:00
abstract：:The earliest diagnosis and treatment of obstructed fetal bladder is reported. Placement of vesico-amniotic shunt at 14.5 weeks of gestation enabled preservation of bilateral renal function and maintenance of normal amniotic fluid volume with normal pulmonary development. The shunt functioned adequately for more than 1...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016348909013286
更新日期：1989-01-01 00:00:00
abstract：:A 50-year-old women was admitted on suspicion of abdominal tumor. Clinical examination and ultrasonography revealed a living fetus of 24.2 weeks' gestational age. Amniocentesis revealed trisomy 18 (Edwards' syndrome). At 34 weeks the fetus died spontaneously, and by cesarean section a stillborn boy of 770 g was delive...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：
更新日期：1988-01-01 00:00:00
abstract：:The cervical mucus plug is a large, complex structure within the cervical canal that is shed shortly before or during labor. We propose that the cervical mucus plug fulfills critical 'gate-keeper' functions based on its physical and immunologic properties, which help prevent ascending infection and preterm labor. The ...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章,评审
doi：10.1080/00016340902852898
更新日期：2009-01-01 00:00:00
abstract：:A survey has been presented of the author's personal methods to treat urge incontinence in women caused by neurogenic disturbances or by urethritis. Denervation of the bladder by unilateral or bilateral resection of the inferior hypogastric plexus is used for neurogenic disturbances with uninhibited bladder contractio...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016347509156747
更新日期：1975-01-01 00:00:00
