Treatment of vaginal recurrence in endometrial cancer. A review.

Abstract:

BACKGROUND:We have reviewed the literature concerning vaginal recurrence in endometrial cancer with emphasis on prognostics and therapeutic results. Compared to the overall outcome of recurrences (11-17 per cent survive more than 3-19 years) the survival rate of strictly vaginal recurrence appears significantly higher (up to 60-70 per cent survive more than 5 years). However, the prognosis deteriorates significantly in cases where recurrences prove to be more widespread. Other factors towards predicting a poor outcome are high age, high stage, high grade, detection of papillary carcinoma, rapid recurrence, location to the lower part of vagina, large tumor size, and previous radiation. METHODS:Different methods of initial treatment and cross-relations between most prognostic factors renders any ranking of prognostic factors almost impossible. RESULTS:Standard treatment of vaginal recurrence including combined external and intra vaginal radiation used for decades have been unable to improve survival rate. CONCLUSION:We suggest a more individualized treatment based on exact delineation of the disease.

authors

Møller LA,Engelholm SA

doi

10.3109/00016349609033275

subject

Has Abstract

pub_date

1996-01-01 00:00:00

pages

1-7

issue

1

eissn

0001-6349

issn

1600-0412

journal_volume

75

pub_type

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