Hormone replacement therapy with tibolone: effects on sexual functioning in postmenopausal women.

Abstract:

OBJECTIVE:Because hormonal changes in postmenopausal women may be accompanied by sexual problems and a worsening of various aspects of libido, the aim of this study was to assess the effect of tibolone (Liviel(R)) on sexual life. METHODS:Postmenopausal first-time users of hormone replacement therapy (HRT) were included in this open, multicenter study. Patients were treated with tibolone 2.5 mg daily for at least 4 months. Both at baseline and after 4 months of treatment, patients were asked to complete two different questionnaires rating the women's subjective assessment of their sexual problems or desires. RESULTS:One hundred and eighty-four women were enrolled to receive HRT with tibolone. Overall, a significant increase in women's satisfaction with their sexual lives and a significant improvement in different aspects of libido was found. CONCLUSION:Tibolone has beneficial effects on several aspects of sexual life in postmenopausal women. These effects may be due to both an increase in genital blood flow and the central estrogenic/androgenic activity.

authors

Egarter C,Topcuoglu A,Vogl S,Sator M

doi

10.1034/j.1600-0412.2002.810711.x

subject

Has Abstract

pub_date

2002-07-01 00:00:00

pages

649-53

issue

7

eissn

0001-6349

issn

1600-0412

pii

aog810711

journal_volume

81

pub_type

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