Premature rupture of fetal membranes changes in collagen type.

Abstract:

:Collagen from the chorioamnion units from premature and term pregnancies was solubilized by limited pepsin digestion and subjected to SDS-PAG electrophoresis. Collagen types were quantitated by densitometry. It was found that collagen type III decreases and collagen type V tends to increase as gestational age advances. Investigating the relative abundance of collagen types at various membrane sites from term pregnancies revealed that type V decreases in the amnion as the rupture site is approached. It is concluded that since type V collagen is more resistant to collagenases, its decrease may predispose that particular site to rupture.

authors

al-Zaid NS,Gumaa KA,Bou-Resli MN,Ibrahim ME

subject

Has Abstract

pub_date

1988-01-01 00:00:00

pages

291-5

issue

4

eissn

0001-6349

issn

1600-0412

journal_volume

67

pub_type

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