Abstract:
:The cervical mucus plug is a large, complex structure within the cervical canal that is shed shortly before or during labor. We propose that the cervical mucus plug fulfills critical 'gate-keeper' functions based on its physical and immunologic properties, which help prevent ascending infection and preterm labor. The viscoelastic properties of the cervical mucus plug are determined by mucins (large glycoproteins), which can inhibit viral replication and exclude larger molecules and bacteria by preventing their diffusion through the plug. Furthermore, the innate and adaptive immunological properties of the cervical mucus plug are well suited for arresting bacterial infection by stimulating a robust inflammatory response. A possible association between an impaired gate-keeper function of the cervical mucus plug and preterm birth is discussed.
journal_name
Acta Obstet Gynecol Scandjournal_title
Acta obstetricia et gynecologica Scandinavicaauthors
Becher N,Adams Waldorf K,Hein M,Uldbjerg Ndoi
10.1080/00016340902852898subject
Has Abstractpub_date
2009-01-01 00:00:00pages
502-13issue
5eissn
0001-6349issn
1600-0412pii
909973412journal_volume
88pub_type
杂志文章,评审abstract::The quality and reliability of pulsed Doppler recordings from branches of the uterine artery were tested by studying 37 normotensive pregnancies and 14 complicated by pregnancy-induced hypertension (PIH) lasting for several minutes. The coefficients of variation of mean velocity and A/B ratio (= peak systolic/end dias...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016348909021008
更新日期:1989-01-01 00:00:00
abstract::Pure uterine fluid, obtained from 18 women in the luteal phase, was pooled and gel filtered. Inhibitory activity against trypsin, chymotrypsin and elastase was present in fractions containing alpha 2-macroglobulin, alpha 1-antitrypsin, alpha 1-antichymotrypsin and antileukoprotease. After solid-phase adsorption with a...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016348609158365
更新日期:1986-01-01 00:00:00
abstract:INTRODUCTION:Cervical cancer is a common malignant tumor in women; most cervical cancer patients are premenopausal. Ovarian resection or preservation remains controversial. The purpose of this study was to discover the risk factors for ovarian metastasis in women with stage I-II cervical cancer. MATERIAL AND METHODS:A...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1111/aogs.13442
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:To determine the perinatal outcome of pregnancy in primiparous women over 35 years of age and to evaluate determinants predicting cesarean delivery in these women. METHODS:Two hundred and seven mothers aged at least 35 years (1.8% of the total deliveries) delivered in the Department of Obstetrics and Gyneco...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.1034/j.1600-0412.2002.810406.x
更新日期:2002-04-01 00:00:00
abstract::As saliva is an easily accessible biological material, compared with 24-hour urine and blood, the salivary concentration of estriol was studied from the 30th to the 41st week of gestation in 268 samples from 124 normal pregnancies. At the same time, venous blood samples were drawn and analyzed for total and unconjugat...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016348109154137
更新日期:1981-01-01 00:00:00
abstract:BACKGROUND:Anal sphincter rupture is a serious complication of vaginal delivery and almost half the affected women have persistent defecatory symptoms despite adequate primary repair. During the past decade, the incidence of anal sphincter ruptures has been increasing in Sweden and is currently estimated to occur in 2....
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:
更新日期:1998-11-01 00:00:00
abstract:BACKGROUND:Oral contraceptives (OC) are the most popular contraception in Denmark. Overall figures on use are well described, but more detailed use patterns according to type and age need to be updated. OBJECTIVES:To assess trends in the use of OC including progestogen-only pills among Danish women in 1998-2010 and to...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0412.2012.01416.x
更新日期:2012-07-01 00:00:00
abstract:OBJECTIVE:To produce normograms of Doppler indices of major fetal arteries and their ratios relative to the ascending aorta in a cohort of appropriately grown for gestational age fetuses. METHODS:Prospective longitudinal study of 70 women with appropriately grown for gestational age fetuses between 24 and 38 weeks' ge...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.0001-6349.2005.00549.x
更新日期:2005-03-01 00:00:00
abstract::Eighty-two gynecological patients with clinical signs of a lower urinary tract infection (UTI) were randomized to 10 days' treatment with either a fixed combination of pivampicillin-pivmecillinam (PAPM) or trimethoprim-sulphamethoxazole (TMPS). The effect of treatment could be evaluated in 25 patients on PAPM and in 1...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.3109/00016348309154228
更新日期:1983-01-01 00:00:00
abstract::Pregnancy outcome was investigated: 1) in fifteen women suffering from idiopathic recurrent spontaneous abortion (RSA) and who had experienced pregnancies with two different partners, and 2) in the mothers, the sisters and wives of the brothers of 90 consecutively referred women with RSA. After adjusting for ascertain...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016349009028702
更新日期:1990-01-01 00:00:00
abstract:OBJECTIVE:To compare 24-hour controlled-release vaginal dinoprostone pessary vs. gel for induction of labor at term in women with an unfavorable cervix. DESIGN:Randomized controlled trial. SETTING:University hospital. POPULATION:A total of 133 women with singleton pregnancies, fetal cephalic presentation, Bishop sco...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章,随机对照试验
doi:10.3109/00016340903575998
更新日期:2010-05-01 00:00:00
abstract::Intramuscular 15(S)15 methyl PGF2α (Prostin 15M, Upjohn) was used for induction of labour in cases of missed abortion and intra-uterine fetal death. The patients received premedication to control the gastrointestinal side effects. Prostin 15M was given at a dose of 250 µg every three hours and escalated whenever requi...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.1111/aogs.1988.67.s145.45
更新日期:1988-01-01 00:00:00
abstract:BACKGROUND:To investigate the ability of bacterial lipopolysaccharide delivered by the intra-uterine route to cause uterine contractions in rabbits, and to assess the suppressive effect of urinary trypsin inhibitor on them. METHODS:Both pregnant and non-pregnant rabbits were chronically implanted with a force-transduc...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016349709047780
更新日期:1997-01-01 00:00:00
abstract:BACKGROUND:There is a lack of established treatment for Chronic pelvic pain (CPP), defined as acyclic pain of at least six months duration. We decided to study the pain-alleviating effects of stretching on defined structures in women with CPP, and the treatment's impact on quality of life variables. DESIGN OF STUDY:An...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章,随机对照试验
doi:10.1080/00016340500495017
更新日期:2006-01-01 00:00:00
abstract::Primary hyperparathyroidism (PHP) is rare during pregnancy and has been claimed to be associated with significant increase of neonatal morbidity and mortality. Whether the well recognized changes in calcium (Ca) and phosphate (Pi) homeostasis occurring in pregnancy might influence the biochemical expression of PHP is ...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016349309021140
更新日期:1993-08-01 00:00:00
abstract::Pregnancy outcomes in 22 consecutively operated women with Müllerian anomalies are described. In 16 women the indication for metroplasty was two or more spontaneous abortions and/or premature deliveries. The frequency of successful pregnancies increased from 5% before to 76% after operation. In 6 women metroplasty was...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016348809004205
更新日期:1988-01-01 00:00:00
abstract:INTRODUCTION:Uncertainty exists regarding the impact of malpresentation on pregnancy outcomes and the optimal mode of delivery in low- and middle-income countries. We sought to compare outcomes between cephalic and non-cephalic pregnancies. MATERIAL AND METHODS:Using the NICHD Global Network's prospective, population-...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.1111/aogs.13502
更新日期:2019-03-01 00:00:00
abstract:OBJECTIVE:To examine whether strenuous working conditions in pregnancy are associated with reduced birthweight. METHOD:Cross-sectional, population based study. Retrospective data collection by questionnaire to parturients in all maternity wards in Norway 16.10-26.11.89, completed before discharge from hospital, with r...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:
更新日期:1998-03-01 00:00:00
abstract:OBJECTIVE:To study the efficacy of performing the tension-free vaginal tape (TVT) procedure concurrently with vaginal pelvic relaxation surgeries in the management of genuine stress incontinence with genital prolapse. MATERIALS AND METHODS:Fifty-eight women were surgically managed. Various vaginal pelvic reconstructiv...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.1034/j.1600-0412.2003.00316.x
更新日期:2003-11-01 00:00:00
abstract::During routine ante-natal testing during the period 1953-73 anti-c was found in the serum of 63 women. Twenty-four of them had received blood transfusion previously and of these 22 were multigravidae. In 39 women pregnancies alone were responsible for the immunization. The anti-c titres of the 42 women giving birth to...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016347709162118
更新日期:1977-01-01 00:00:00
abstract::By using DNA cytofluorometry, DNA ploidy and the distribution pattern of human trophoblasts at different sites were studied throughout pregnancy, and the proliferative activity during cell differentiation of trophoblasts was discussed. In the first and second trimesters, cytofluorometric nuclear DNA analysis demonstra...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016349209007940
更新日期:1992-01-01 00:00:00
abstract:BACKGROUND:Anal sphincter tears during vaginal delivery are a major cause of anal incontinence. We wanted to assess the incidence in a Norwegian county where primary repairs are performed in four hospitals using similar per- and postoperative protocol for the treatment of such injuries. METHODS:A postal questionnaire ...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.0001-6349.2004.00647.x
更新日期:2004-10-01 00:00:00
abstract:INTRODUCTION:Endometriosis is associated with hyperperistalsis and dysperistalsis in the uterus, and it has been shown that progesterone leads to a decrease in uterine contractility. The synthetic gestagen dienogest is often administered in women who are receiving conservative treatment for endometriosis, and it may be...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.1111/aogs.13428
更新日期:2018-11-01 00:00:00
abstract:INTRODUCTION:An estimated 2.6 million stillbirths occur worldwide each year. A standardized classification system setting out possible cause of death and contributing factors is useful to help obtain comparative data across different settings. We undertook a systematic review of stillbirth classification systems to hig...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章,评审
doi:10.1111/aogs.13126
更新日期:2017-05-01 00:00:00
abstract:OBJECTIVES:To evaluate the accuracy of different preoperative modalities for staging of endometrial cancer to restrict extensive surgery to patients at high risk of metastatic disease. SETTING:Aarhus University Hospital. POPULATION:156 women referred in 2006-2011 because of atypical endometrial hyperplasia (G0) or en...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.1111/aogs.12103
更新日期:2013-05-01 00:00:00
abstract::A tumor found in endometrial curettings of a 35-year-old woman was originally interpreted as malignant. Review of the slides and additional curettings revealed that the tumor was in reality a plexiform leiomyoma. Attention is drawn to the fact that this rare tumor may be present in endometrial curettings. ...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016348609157044
更新日期:1986-01-01 00:00:00
abstract::A 23 year old woman, who was known to be in remission from thymic carcinoma, presented in her first trimester. She had previously been treated with radiation and chemotherapy. Her pregnancy was complicated by fever and contractions at 30 weeks and ended with the birth of a live preterm male infant. Subsequent investig...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016349209021082
更新日期:1992-07-01 00:00:00
abstract::Persistently elevated levels of serum human chorionic gonadotropin (hCG) in women call for a tumor investigation, if pregnancy can be ruled out. We present a case of increased hCG concentrations for 1 1/2 years. Radiolabelled antibody directed against the hCG molecule indicated the source of production to be a chorioc...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016348909020999
更新日期:1989-01-01 00:00:00
abstract::International guidelines recommend that health-care providers initiate discussions about the impact of treatment on fertility with cancer patients of reproductive age, or with parents/legal guardians of children, as early as possible in the treatment process. Still, both physicians and patients confirm that this is no...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章,评审
doi:10.1111/aogs.13551
更新日期:2019-05-01 00:00:00
abstract::One hundred and ten singleton breech infants with a birth-weight less than 2 500 g have been delivered at Huddinge University Hospital during the years 1972-78. The cesarean section rate was 30.1 per cent. Vaginal and abdominal deliveries were compared with regard to perinatal mortality and asphyxial morbidity at birt...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016348109154124
更新日期:1981-01-01 00:00:00