Abstract：
BACKGROUND AND OBJECTIVES:The emotion of disgust has been suggested as a factor contributing to a poor response to Cognitive Behaviour Therapy (CBT) in the treatment of Obsessive Compulsive Disorder (OCD). However, only limited information is available about the phenomenology of disgust in clinical OCD and the physiological mechanisms involved. This case series was designed to explore the phenomenology of OCD and the physiological activity associated with the emotion of disgust. METHODS:State disgust and heart rate was measured in eleven participants attending treatment for OCD during exposure relevant to their individual formulation. RESULTS:All participants with contamination and most patients with blood and injury related fears experienced a prominent increase in state disgust during exposure. These participants also had absent heart rate acceleration during exposure. Disgust response correlated with heart rate response (r = -0.63, p < 0.01) and Root Mean Square of Successive Differences (RMSSD) (r = 0.52, p < 0.01). LIMITATIONS:The design using ecologically valid stimuli and the limited number of participants did not allow between subject comparisons or more detailed analysis of relationship between trait and state disgust and between disgust and severity of OCD. CONCLUSIONS:Our findings show that a large proportion of our case series with OCD experience prominent disgust with signs of increased vagal tonus during their exposure. Such experiences differ from the concept of adrenergic activation used for psychoeducation in CBT and appraisals of harm and this may result in poorer therapeutic outcome.
journal_name
J Behav Ther Exp Psychiatryjournal_title
Journal of behavior therapy and experimental psychiatryauthors
Duncko R,Veale Ddoi
10.1016/j.jbtep.2016.01.001subject
Has Abstractpub_date
2016-06-01 00:00:00pages
92-9eissn
0005-7916issn
1873-7943pii
S0005-7916(16)30001-5journal_volume
51pub_type
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journal_title：Journal of behavior therapy and experimental psychiatry
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journal_title：Journal of behavior therapy and experimental psychiatry
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journal_title：Journal of behavior therapy and experimental psychiatry
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journal_title：Journal of behavior therapy and experimental psychiatry
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journal_title：Journal of behavior therapy and experimental psychiatry
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journal_title：Journal of behavior therapy and experimental psychiatry
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journal_title：Journal of behavior therapy and experimental psychiatry
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journal_title：Journal of behavior therapy and experimental psychiatry
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journal_title：Journal of behavior therapy and experimental psychiatry
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journal_title：Journal of behavior therapy and experimental psychiatry
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journal_title：Journal of behavior therapy and experimental psychiatry
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journal_title：Journal of behavior therapy and experimental psychiatry
pub_type： 临床试验,杂志文章,随机对照试验
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journal_title：Journal of behavior therapy and experimental psychiatry
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journal_title：Journal of behavior therapy and experimental psychiatry
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journal_title：Journal of behavior therapy and experimental psychiatry
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journal_title：Journal of behavior therapy and experimental psychiatry
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journal_title：Journal of behavior therapy and experimental psychiatry
pub_type： 杂志文章
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abstract：BACKGROUND AND OBJECTIVES:Trauma-related rumination has been found to be an important maintaining factor for PTSD. On the background of the processing mode account of ruminative thinking, this study tested whether the relationship between rumination and analogue PTSD symptoms can be modified by training participants in...
journal_title：Journal of behavior therapy and experimental psychiatry
pub_type： 杂志文章
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