Abstract:
PURPOSE:Endoscopic resection is a widely used technique for treatment of large colorectal adenomas, but few data are available including only lesions larger than ≥2 cm. The aim of this study is to evaluate the complication and recurrence rate after endoscopic resection of high-risk colorectal adenomas ≥3 cm in size. METHODS:Retrospective analysis of a prospectively maintained database of patients undergoing polypectomy of large colorectal polyps of ≥3 cm. RESULTS:In 341 patients, 360 colorectal adenomas with a mean size of 3.9 cm were resected endoscopically. In 25 patients, a complication including 22 delayed bleedings (6.5%) and three perforations (0.9%) occurred. Single-variate analysis showed an increasing risk of complications for larger adenomas (3.9 vs. 4.6 cm; p ≤ 0.05). Two hundred twelve patients with 224 adenomas had undergone at least one documented follow-up endoscopy with a medium follow-up period of 16 months. In 95 resected lesions (42.4%), a residual adenoma occurred in the first follow-up colonoscopy (n = 88, 92.6%) or a recurrent adenoma occurred after at least one negative follow-up colonoscopy (n = 7, 7.4%). In multivariate analysis, risk factors were lesion size, sessile growth pattern, and the performing endoscopist. The complication and recurrence rate correlated inversely between endoscopists. CONCLUSIONS:The present study is the largest study showing complication and recurrence rates after colorectal polypectomy of advanced colorectal adenomas of ≥3 cm in size. Polyp size was identified as the most important risk factor for complications. For the first time, this study shows that the complication rate after colorectal polypectomy of large adenomas is correlated inversely with the residual and/or recurrence rate.
journal_name
Int J Colorectal Disjournal_title
International journal of colorectal diseaseauthors
Seidel J,Färber E,Baumbach R,Cordruwisch W,Böhmler U,Feyerabend B,Faiss Sdoi
10.1007/s00384-015-2498-xsubject
Has Abstractpub_date
2016-03-01 00:00:00pages
603-11issue
3eissn
0179-1958issn
1432-1262pii
10.1007/s00384-015-2498-xjournal_volume
31pub_type
杂志文章abstract:PURPOSE:To identify factors associated with timing of stoma reversal after rectal cancer surgery in a large Swedish register-based cohort. METHODS:Three thousand five hundred sixty-four patients with rectal cancer who received a protective stoma during surgery in 2007-2013 were identified in the Swedish colorectal can...
journal_title:International journal of colorectal disease
pub_type: 杂志文章
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abstract:PURPOSE:Inflammatory bowel disease has been associated with neurological symptoms including restless legs syndrome. Here, we investigated the impact of restless legs syndrome in patients with inflammatory bowel disease on sleep, fatigue, mood, cognition, and quality of life. METHODS:Two groups of inflammatory bowel di...
journal_title:International journal of colorectal disease
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abstract:PURPOSE:Some recent studies have suggested that fluorescence angiography with indocyanine green (ICG) might be useful for preventing anastomotic leakage (AL) after laparoscopic colorectal surgery. However, its efficacy has not been proven. We evaluated whether intraoperative ICG fluorescence angiography could decrease ...
journal_title:International journal of colorectal disease
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journal_title:International journal of colorectal disease
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更新日期:2014-11-01 00:00:00
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journal_title:International journal of colorectal disease
pub_type: 杂志文章,评审
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更新日期:2011-08-01 00:00:00
abstract::Colorectal surgery is still associated with a significant morbidity and mortality rate, mostly related to suture failure. We have carried out a randomized experimental study in dogs on colonic anastomoses exposed to a number of anastomotic risk situations. A total of 42 dogs was used. They were divided into three stud...
journal_title:International journal of colorectal disease
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abstract::Although the cause of Crohn's disease remains obscure, considerable progress has been made in recent years in unraveling the pathogenesis of the inflammatory processes seen in chronic idiopathic inflammatory bowel diseases. Th-1 lymphocytes seem to orchestrate the inflammation through the production of proinflammatory...
journal_title:International journal of colorectal disease
pub_type: 杂志文章,评审
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journal_title:International journal of colorectal disease
pub_type: 杂志文章,评审
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abstract:BACKGROUND AND AIM:Sessile serrated adenoma/polyps (SSAPs) are suspected to have a high malignant potential, although few reports have evaluated the incidence of carcinomas derived from SSAPs using the new classification for serrated polyps (SPs). The aim of study was to compare the frequency of cancer coexisting with ...
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pub_type: 临床试验,杂志文章
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abstract::Cryosurgery is one of the palliative treatment options to decrease local symptoms due to rectal carcinoma. A total of 106 patients (aged 45-92 years) underwent palliative cryosurgery for primary rectal cancer. Inclusion criteria were prohibitive surgical risk, unresectability, distant metastases, patient refusal of su...
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pub_type: 临床试验,杂志文章
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pub_type: 已发布勘误
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更新日期:2020-04-20 00:00:00
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更新日期:2018-09-01 00:00:00
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更新日期:2018-07-01 00:00:00
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journal_title:International journal of colorectal disease
pub_type: 杂志文章
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更新日期:1994-05-01 00:00:00
abstract:PURPOSE:Use of biosutures in animal models of colonic anastomoses is associated with decreased adhesions without affecting anastomotic strength. This study aimed to evaluate the effect of biosutures on colonic anastomoses kept free of adhesions by peritoneal instillation of icodextrin 4%. METHODS:Three types of coloni...
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更新日期:2010-12-01 00:00:00