Analysing breast tissue composition with MRI using currently available short, simple sequences.

Abstract:

AIM:To determine the most robust commonly available magnetic resonance imaging (MRI) sequence to quantify breast tissue composition at 1.5 T. MATERIALS AND METHODS:Two-dimensional (2D) T1-weighted, Dixon fat, Dixon water and SPAIR images were obtained from five participants and a breast phantom using a 1.5 T Siemens Aera MRI system. Manual segmentation of the breasts was performed, and an in-house computer program was used to generate signal intensity histograms. Relative trough depth and relative peak separation were used to determine the robustness of the images for quantifying the two breast tissues. Total breast volumes and percentage breast densities calculated using the four sequences were compared. RESULTS:Dixon fat histograms had consistently low relative trough depth and relative peak separation compared to those obtained using other sequences. There was no significant difference in total breast volumes and percentage breast densities of the participants or breast phantom using Dixon fat and 2D T1-weighted histograms. Dixon water and SPAIR histograms were not suitable for quantifying breast tissue composition. CONCLUSION:Dixon fat images are the most robust for the quantification of breast tissue composition using a signal intensity histogram.

journal_name

Clin Radiol

journal_title

Clinical radiology

authors

Chau AC,Hua J,Taylor DB

doi

10.1016/j.crad.2015.11.020

subject

Has Abstract

pub_date

2016-03-01 00:00:00

pages

287-92

issue

3

eissn

0009-9260

issn

1365-229X

pii

S0009-9260(15)00482-1

journal_volume

71

pub_type

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