Familial Blau syndrome without uveitis caused by a novel mutation in the nucleotide-binding oligomerization domain-containing protein 2 gene with good response to infliximab.

abstract：:Tetracycline is well known to cause pigmentation of various body tissues, such as teeth, bone, lunulae, conjunctivae, and lymph nodes. It has not been reported to cause discoloration of the skin, unlike its semisynthetic derivative, minocycline. We report an 18-year-old girl who developed lower extremity pigmentation ...

journal_title：Pediatric dermatology

authors： Hawfield W,Goodrich R,Warren S,Morrell D

更新日期：2004-03-01 00:00:00

abstract：:Nevoid basal cell carcinoma syndrome (Gorlin syndrome) is a rare, autosomal dominant syndrome that is known to have variable expressivity in multiple organ systems. We describe the case of a young male child with nevoid basal cell carcinoma syndrome and scalp lesions, including a branchial cleft cyst with respiratory ...

journal_title：Pediatric dermatology

authors： Findley AB,Pride H

更新日期：2010-03-01 00:00:00

abstract：:Telangiectasia macularis eruptiva perstans (TMEP) is a form of mastocytosis. It is an uncommon condition, particularly in children. The disorder is characterized by telangiectatic macules and generally has a good prognosis, with little tendency to urticate or cause constitutional symptoms. We report a girl who present...

journal_title：Pediatric dermatology

authors： Gibbs NF,Friedlander SF,Harpster EF

更新日期：2000-05-01 00:00:00

abstract：:We describe three adolescents with eruptive linear lesions of the back, abdomen, and extremities distributed along the lines of Blaschko. Clinically one of these lesions resembled an epidermal nevus in its morphology and distribution. A biopsy specimen demonstrated the typical histology of lichen planus (LP). There ha...

journal_title：Pediatric dermatology

authors： Kabbash C,Laude TA,Weinberg JM,Silverberg NB

更新日期：2002-11-01 00:00:00

abstract：:Clinical aspects of sequestrated meningocele can be varied, causing difficulties in histopathological diagnosis. The meningeal tissue is scanty and appears as nonspecific connective tissue, therefore it may be overlooked. One classical and two unusual clinical presentations of sequestrated meningocele are described: o...

journal_title：Pediatric dermatology

authors： Khallouf R,Fétissof F,Machet MC,Stephanov E,Lechrist J,Lorette G

更新日期：1994-12-01 00:00:00

abstract：:We present a case of an infant with severe atopic dermatitis infected with Streptococcus pyogenes who presented with pustules, honey-colored crusts, and punched-out erosions with scalloped borders mimicking eczema herpeticum or eczema coxsackium. We draw attention to this case to highlight the similar clinical appeara...

journal_title：Pediatric dermatology

authors： Shayegan LH,Richards LE,Morel KD,Levin LE

更新日期：2019-11-01 00:00:00

abstract：:We report a 2-year-old boy with a plaque on the upper arm composed of multiple 2- to 3-mm leiomyomata which developed at the age of 3 months and have been unchanged since. Immunohistologically there was positive staining for the muscle intermediate filament desmin. We discuss the unusual clinical presentation and poss...

journal_title：Pediatric dermatology

authors： Henderson CA,Ruban E,Porter DI

更新日期：1997-07-01 00:00:00

abstract：:Loose anagen hair syndrome (LAHS) is an uncommonly reported autosomal dominant hair disorder with incomplete penetrance that primarily affects children but is occasionally seen in adults. LAHS is characterized by the ability to easily and painlessly extract unsheathed anagen hairs from the scalp with gentle traction. ...

journal_title：Pediatric dermatology

authors： Dey V,Thawani M

更新日期：2013-09-01 00:00:00

abstract：:Prurigo nodularis is an uncommon pediatric cutaneous disorder that is associated with intense pruritus. We report a teenager with prurigo nodularis as the presenting sign of stage IIA Hodgkin's disease, primarily in the mediastinum. The pruritus and associated cutaneous lesions resolved with combination chemotherapy d...

journal_title：Pediatric dermatology

authors： Shelnitz LS,Paller AS

更新日期：1990-06-01 00:00:00

abstract：:Lindane (gamma benzene hexachloride) is a widely prescribed topical scabicide because of its efficacy and cost-effectiveness. Although toxicity from a single proper application of lindane is generally not observed, the hazards of repeated applications, industrial exposure, and accidental ingestion have been well docum...

journal_title：Pediatric dermatology

authors： Bhalla M,Thami GP

更新日期：2004-09-01 00:00:00

abstract：:Two hundred forty-seven healthy newborns were investigated in a prospective cohort descriptive study. Information on phenotype and obstetric and parental history was collected. A positive association was found between erythema toxicum neonatorum and season of birth (spring and summer), whereas parental history of any ...

journal_title：Pediatric dermatology

authors： Rodríguez-García C,Rodríguez C,Sánchez R,González-Hernández S,Pérez-Robayna N,Guimerá F,Aguirre-Jaime A

更新日期：2012-03-01 00:00:00

abstract：:Linear immunoglobulin A bullous dermatosis (LABD) is an autoimmune blistering disease that most commonly presents in preschool-aged children. There have been few neonatal reports, all of which had life-threatening aerodigestive complications requiring mechanical intervention and systemic therapy. We present a case of ...

journal_title：Pediatric dermatology

authors： Julapalli MR,Brandon KL,Rosales CM,Grover RK,Plunkett RW,Metry DW

更新日期：2012-09-01 00:00:00

abstract：:Lymphangiomas are congenital malformations of the lymphatic system. We report a 10-year-old boy with lymphatic malformation of the scrotum, which presented as a multiloculated scrotal mass associated with edema of the left thigh and left cryptorchidism. Histopathologic examination showed scrotal lymphangioma cavernosu...

journal_title：Pediatric dermatology

authors： Vikicevic J,Milobratovic D,Vukadinovic V,Golubovic Z,Krstic Z

更新日期：2007-11-01 00:00:00

abstract：:Leukemia cutis and facial nerve palsy are rare presenting symptoms of leukemia. This report describes a case of acute T-cell lymphoblastic leukemia (ALL) presenting with only these two symptoms, a presentation of ALL that, to our knowledge, has not been previously described. It serves to alert physicians to look for u...

journal_title：Pediatric dermatology

authors： Gold HL,Grynspan D,Kanigsberg N

更新日期：2014-05-01 00:00:00

abstract：:Phrynoderma is a distinctive form of follicular hyperkeratosis associated with nutritional deficiency. Although originally thought to represent vitamin A deficiency, several studies have demonstrated multiple etiologies. Characteristic skin lesions are hyperkeratotic papules that first appear on the extensor surfaces ...

journal_title：Pediatric dermatology

authors： Maronn M,Allen DM,Esterly NB

更新日期：2005-01-01 00:00:00

abstract：:Langerhans cell histiocytosis is a rare proliferative disorder where pathologic Langerhans cells accumulate in a variety of organs. Historically, the nomenclature regarding this entity has been confusing because the disease had been subcategorized simply based upon the different clinical manifestations. In the followi...

journal_title：Pediatric dermatology

authors： Satter EK,High WA

更新日期：2008-05-01 00:00:00

abstract：:Menkes's syndrome (trichopoliodystrophy) is an x-linked, recessive genodermatosis characterized by hair defects, severe retardation, convulsions, progressive neurologic deterioration, and early death. Recent studies in copper metabolism suggest that Menkes's syndrome may be a storage disease in which copper is irrever...

journal_title：Pediatric dermatology

authors： Maddox JL Jr,Odom RB,Goette DK

更新日期：1984-04-01 00:00:00

abstract：:Successful management of toxic epidermal necrolysis (TEN) with tumor necrosis factor-α inhibitors has been described in adults. We present a case of a 7-year-old boy with infection-associated TEN, diagnosed by typical clinical and histopathological features, most likely caused by Mycoplasma pneumoniae. Treatment with ...

journal_title：Pediatric dermatology

authors： Chafranska L,Saunte DM,Behrendt N,Nygaard U,Christensen RJ,Sand C,Jemec GB

更新日期：2019-05-01 00:00:00

abstract：:Orofacial granulomatosis, a rare disease in childhood, is characterized by orofacial swelling in the absence of systemic disease. We report the case of a 12-year-old girl with asymptomatic erythematous infiltration of her upper lip, cheeks, and chin that had persisted for more than 2 years; biopsy confirmed granuloma ...

journal_title：Pediatric dermatology

authors： Lalosevic J,Gajic-Veljic M,Nikolic M

更新日期：2017-11-01 00:00:00

abstract：:Halo dermatitis is a pruritic, eczematous eruption on pigmented nevi and halo nevi in young adults. It may be mistaken for nummular eczema, psoriasis, or fungal skin infection. Awareness of halo dermatitis will possibly reveal more cases in children, which have been reported only rarely. ...

journal_title：Pediatric dermatology

authors： Shifer O,Tchetchik R,Glazer O,Metzker A

更新日期：1992-09-01 00:00:00

abstract：:Nodular lichen myxedematosus (LM) is a rare disease and is one of the five subtypes of localized LM. It is distinctly characterized by multiple nodules on the trunk and limbs with or without papular lesions. A healthy 6-year-old boy presented with complaints of "knots" on his right chest, upper limb, and thigh for 4 m...

journal_title：Pediatric dermatology

authors： Zeng R,Li M,Jiang Y,Liu W

更新日期：2014-11-01 00:00:00

abstract：:Pyoderma gangrenosum (PG) is an inflammatory neutrophilic dermatosis that may present with limited to severe disease, posing a therapeutic challenge. A 7-year-old African female who presented with extensive PG showed a remarkable response to corticosteroid wrap monotherapy. ...

journal_title：Pediatric dermatology

authors： Chateau A,Makhubele J,Dlova N

更新日期：2020-09-06 00:00:00

abstract：:An 8-year-old girl had Crohn's disease of the vulva 16 months before the onset of intestinal symptoms. At the time of diagnosis she had no evidence of systemic disease. Cutaneous and intestinal lesions responded rapidly to corticosteroids and metronidazole. Crohn's disease must be considered in the differential diagno...

journal_title：Pediatric dermatology

authors： Lally MR,Orenstein SR,Cohen BA

更新日期：1988-05-01 00:00:00

abstract：:Woolly hair nevus is a rare syndrome that presents as woolly hair in restricted areas of the scalp and may be associated with pigmented macules or epidermal nevus on the body. Here, we report a case of woolly hair nevus, linear pigmentation, and multiple epidermal nevi with a somatic HRAS c.34G>A(p.G12S) mutation. ...

journal_title：Pediatric dermatology

authors： Nishihara K,Tohyama M,Kubo A

更新日期：2019-05-01 00:00:00

abstract：:An 8-month-old male infant had fever, polymorphonuclear leukocytosis, and tender, firm, elevated erythematous plaques on his face, trunk, and extremities. Histologic examination revealed a dense, perivascular, polymorphonuclear, inflammatory cell infiltrate with nuclear dust in the dermis and intrafollicular abscesses...

journal_title：Pediatric dermatology

authors： Kibbi AG,Zaynoun ST,Kurban AK,Najjar SS

更新日期：1985-11-01 00:00:00

abstract：:Discoid lupus erythematosus (DLE) is the most common variant of cutaneous chronic lupus erythematosus (CLE). Sun protection, topical corticosteroids, and antimalarials constitute the first-line options for treatment. In refractory cases, alternative antimalarials, methotrexate, retinoids, and thalidomide have been uti...

journal_title：Pediatric dermatology

authors： Tran B,Yazdani Abyaneh MA,Wu J

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:In recent years propranolol has become the treatment of choice for infantile hemangiomas (IHs). There is broad variation in the approach to propranolol initiation in clinical practice. This retrospective study explored the effectiveness of routine pre-treatment ECG in screening infants being considered for s...

journal_title：Pediatric dermatology

authors： Yarbrough KB,Tollefson MM,Krol AL,Leitenberger SL,Mann JA,MacArthur CJ

更新日期：2016-11-01 00:00:00

abstract：:Normolipemic plane xanthoma normally occurs in adults. We report the atypical instance of a 9-year-old boy who developed disseminated, flat, yellow-brown plaques up to 2 to 3 cm without any complaints. The histology showed the hallmarks of xanthoma, including the presence of CD68+ foam cells and Touton giant cells. No...

journal_title：Pediatric dermatology

authors： Hofmann M,Zappel K,Trefzer U,Audring H,Albrecht-Nebe H,Sterry W,Blume-Peytavi U

更新日期：2005-03-01 00:00:00

abstract：:Microcomedonal lesions can be aesthetically and psychologically displeasing. The burden of comedones increases when considering their frequency and demand for time-consuming attention. The objective of the current study was to describe a novel technique to facilitate open microcomedone extraction. The instrumentation ...

journal_title：Pediatric dermatology

authors： Naimer SA

更新日期：2016-11-01 00:00:00

abstract：:Acute genital ulcers rarely occur in nonsexually active young girls. When present, they can cause significant physical and emotional distress for the patient and her parents, and prompt an evaluation for sexual abuse and sexually transmitted diseases. With this review, we aim to further characterize acute genital ulce...

journal_title：Pediatric dermatology

authors： Rosman IS,Berk DR,Bayliss SJ,White AJ,Merritt DF

更新日期：2012-03-01 00:00:00