Comparison of the clinical performance of upper abdominal PET/DCE-MRI with and without concurrent respiratory motion correction (MoCo).

abstract：PURPOSE:Positron emission tomography (PET) imaging of serotonin 2A (5-HT(2A)) receptors with agonist tracers holds promise for the selective labelling of 5-HT(2A) receptors in their high-affinity state. We have previously validated [(11)C]Cimbi-5 and found that it is a 5-HT(2A) receptor agonist PET tracer. In an attemp...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Ettrup A,Hansen M,Santini MA,Paine J,Gillings N,Palner M,Lehel S,Herth MM,Madsen J,Kristensen J,Begtrup M,Knudsen GM

更新日期：2011-04-01 00:00:00

abstract：PURPOSE:The purpose of this study was to evaluate the usefulness of L-4-borono-2-18F-fluoro-phenylalanine (18F-FBPA) as a tumor-specific probe, in comparison to 18F-FDG and 11C-methionine (Met), focusing on its transport selectivity by L-type amino acid transporter 1 (LAT1), which is highly upregulated in cancers. MET...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Watabe T,Ikeda H,Nagamori S,Wiriyasermkul P,Tanaka Y,Naka S,Kanai Y,Hagiwara K,Aoki M,Shimosegawa E,Kanai Y,Hatazawa J

更新日期：2017-02-01 00:00:00

abstract：PURPOSE:Previous functional neuroimaging studies suggest that selective aspects of the brain serotonin (5-HT) system change during the aging process. Here, we assessed the effects of aging on the brain regional alpha-[(11)C]methyl-L: -tryptophan (alpha-[(11)C]MTrp) trapping rate constant (K*; microl.g(-1).min(-1)), whi...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Rosa-Neto P,Benkelfat C,Sakai Y,Leyton M,Morais JA,Diksic M

更新日期：2007-08-01 00:00:00

abstract：PURPOSE:To study the feasibility of the in vivo [18F]-DPA-714 TSPO positron emission tomography (PET) to detect glial activation in a rat model of progressive parkinsonism induced by viral-mediated overexpression of A53T mutated human α-synuclein (hα-syn) in the substantia nigra pars compacta (SNpc). METHODS:We conduc...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Rodríguez-Chinchilla T,Quiroga-Varela A,Molinet-Dronda F,Belloso-Iguerategui A,Merino-Galan L,Jimenez-Urbieta H,Gago B,Rodriguez-Oroz MC

更新日期：2020-10-01 00:00:00

abstract：PURPOSE:Tau pathology progression in Alzheimer's disease (AD) is explained through the network degeneration hypothesis and the neuropathological Braak stages; however, the compatibility of these models remains unclear. METHODS:We utilized [18F]AV-1451 tau-PET scans of 39 subjects with AD and 39 sex-matched amyloid-neg...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Seemiller J,Bischof GN,Hoenig MC,Tahmasian M,van Eimeren T,Drzezga A,and the Alzheimer’s Disease Neuroimaging Initiative.

更新日期：2021-01-18 00:00:00

abstract：:Oxygen (O(2)) inhalation after acute myocardial ischaemia has long been a part of standard therapy in cardiology. It has also been demonstrated that therapeutic hyperoxia diminishes myocardial stunning. The aim of this pilot study was to investigate whether the uptake kinetics of the myocardial perfusion agent technet...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Basoglu T,Yapici O,Aksakal E,Sahin M,Canbaz F,Albayrak S,Yesildag O

更新日期：2002-11-01 00:00:00

abstract：PURPOSE:Despite modern CT systems and expert evaluators, the diagnostic performance of coronary CT angiography is limited by overestimation of vessel stenosis which reduces the positive predictive value (PPV) of the test. The aim of this study was to evaluate the performance of combined cardiac PET/64-detector CT angio...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Groves AM,Speechly-Dick ME,Kayani I,Pugliese F,Endozo R,McEwan J,Menezes LJ,Habib SB,Prvulovich E,Ell PJ

更新日期：2009-12-01 00:00:00

abstract：INTRODUCTION:The quantitative imaging features (radiomics) that can be obtained from the different modalities of current-generation hybrid imaging can give complementary information with regard to the tumour environment, as they measure different morphologic and functional imaging properties. These multi-parametric ima...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Castiglioni I,Gallivanone F,Soda P,Avanzo M,Stancanello J,Aiello M,Interlenghi M,Salvatore M

更新日期：2019-12-01 00:00:00

abstract：:Functional brain imaging plays an important role in seizure focus localisation. However, truly ictal single-photon emission tomography (SPET) studies are not routinely performed owing to technical problems associated with the use of tracers and methodological and logistical difficulties. In this study we tried to reso...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Calcagni ML,Giordano A,Bruno I,Parbonetti G,Di Giuda D,De Rossi G,Troncone L,Colicchio G

更新日期：2002-10-01 00:00:00

abstract：PURPOSE:Although two norepinephrine transporter (NET) radioligands, (S,S)-[(18)F]FMeNER-D(2) and (S,S)-[(11)C]MeNER, have been reported to have different characteristics, there has not been a direct comparative study in vivo. METHODS:In this preliminary study, two rhesus monkeys underwent three PET measurements each, ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Takano A,Gulyás B,Varrone A,Halldin C

更新日期：2009-11-01 00:00:00

abstract：:Jérôme Barriere was inadvertently missing in the original version of this article. He has participated to the study design, protocol writing and inclusion of a significant number of patients. ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Humbert O,Bourg V,Mondot L,Gal J,Bondiau PY,Fontaine D,Barriere J,Saada-Bouzid E,Paquet M,Chardin D,Almairac F,Vandenbos F,Darcourt J

更新日期：2019-07-01 00:00:00

abstract：:We prospectively studied 43 patients with solitary cold thyroid nodules greater than 1.5 cm in diameter to determine the comparative diagnostic value of radionuclide thyroid angiography (RTA), technetium-99m methoxyisobutylisonitrile ((99m)Tc-MIBI) scintigraphy and power Doppler ultrasonography (PDUS) in the different...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Demirel K,Kapucu O,Yücel C,Ozdemir H,Ayvaz G,Taneri F

更新日期：2003-05-01 00:00:00

abstract：:Inflammation plays a major role in the development of many diseases. This review article summarizes recent research in the field of in vivo imaging of inflammation. Novel methodologies using PET with (68)Ga peptides targeting, for example, vascular adhesion protein 1 are discussed. ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Roivainen A,Jalkanen S,Nanni C

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:The clinical problem in suspected aortoiliac graft infection (AGI) is to obtain proof of infection. Although 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography scanning (PET) has been suggested to play a pivotal role, an evidence-based interpretation is lacking. The objective of this retrospective...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Saleem BR,Beukinga RJ,Boellaard R,Glaudemans AW,Reijnen MM,Zeebregts CJ,Slart RH

更新日期：2017-05-01 00:00:00

abstract：UNLABELLED:The aim of this study was to evaluate the feasibility of using [(18)F] 3'-deoxy-3'-fluorothymidine (FLT) positron emission tomography (PET) for the diagnosis and grading of brain tumors. METHODS:The patient population comprised 26 patients (15 males, 11 females) with brain tumors (n=18) or nontumorous lesio...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Choi SJ,Kim JS,Kim JH,Oh SJ,Lee JG,Kim CJ,Ra YS,Yeo JS,Ryu JS,Moon DH

更新日期：2005-06-01 00:00:00

abstract：PURPOSE:To compare the performance characteristics of positron emission mammography (PEM) with those of whole-body PET (WBPET) and PET/CT in women with newly diagnosed breast cancer. METHODS:A total of 178 women consented to PEM for presurgical planning in an IRB-approved protocol and also underwent either WBPET (n = ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Kalinyak JE,Berg WA,Schilling K,Madsen KS,Narayanan D,Tartar M

更新日期：2014-02-01 00:00:00

abstract：PURPOSE:Improved bifunctional chelates (BFCs) are needed to facilitate efficient (64)Cu radiolabeling of monoclonal antibodies (mAbs) under mild conditions and to yield stable, target-specific agents. The utility of two novel BFCs, 1-Oxa-4,7,10-triazacyclododecane-5-S-(4-isothiocyanatobenzyl)-4,7,10-triacetic acid (p-S...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Ferreira CL,Yapp DT,Crisp S,Sutherland BW,Ng SS,Gleave M,Bensimon C,Jurek P,Kiefer GE

更新日期：2010-11-01 00:00:00

abstract：PURPOSE:This meta-analysis summarized the accuracy of stress myocardial perfusion scintigraphy (MPS) and stress echocardiography for the diagnosis of coronary artery disease (CAD) in patients with arterial hypertension. METHODS:We searched for studies in which stress MPS or stress echocardiography were performed to de...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Gargiulo P,Petretta M,Bruzzese D,Cuocolo A,Prastaro M,D'Amore C,Vassallo E,Savarese G,Marciano C,Paolillo S,Filardi PP

更新日期：2011-11-01 00:00:00

abstract：PURPOSE:Continuous bed motion has recently been introduced for whole-body PET/CT, and represents a paradigm shift towards individualized and flexible acquisition without the limitations of bed position-based planning. Increased patient comfort due to lack of abrupt table position changes may be another albeit still unp...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Schatka I,Weiberg D,Reichelt S,Owsianski-Hille N,Derlin T,Berding G,Bengel FM

更新日期：2016-04-01 00:00:00

abstract：PURPOSE:The molecular imaging of tumour neoangiogenesis currently represents a major field of research for the diagnostic and treatment strategy of solid tumours. Endothelial cells from tumour neovessels overexpress the alpha(v)beta(3) integrin, which selectively binds to Arg-Gly-Asp (RGD)-containing peptides. We evalu...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Sancey L,Ardisson V,Riou LM,Ahmadi M,Marti-Batlle D,Boturyn D,Dumy P,Fagret D,Ghezzi C,Vuillez JP

更新日期：2007-12-01 00:00:00

abstract：PURPOSE:The goal of this study is to determine the technical accuracy of segmental perfusion parameters assessed with quantitative cardiac PET imaging in the evaluation of coronary artery disease (CAD) in patients with stable angina. METHODS:A cohort of patients who participated in the EVINCI protocol underwent an eva...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Berti V,Sciagrà R,Neglia D,Pietilä M,Scholte AJ,Nekolla S,Rouzet F,Pupi A,Knuuti J

更新日期：2016-07-01 00:00:00

abstract：PURPOSE:The folate receptor (FR) is frequently overexpressed in a variety of tumor types and, hence, an interesting target for radionuclide therapy. The aim of this study was to evaluate a new class of albumin-binding radioconjugates comprising 5-methyltetrahydrofolate (5-MTHF) as a targeting agent and to compare their...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Guzik P,Benešová M,Ratz M,Monné Rodríguez JM,Deberle LM,Schibli R,Müller C

更新日期：2020-10-15 00:00:00

abstract：PURPOSE:The purpose of this study was to map treatment-induced (99m)Tc-Hynic-rh-annexin V uptake in normal tissues using co-registration of SPECT and CT. METHODS:Nineteen patients (11 male, 8 female, mean age 57 years) with various malignant tumours (12 lymphomas, four non-small cell lung cancers and three head and ne...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Kartachova MS,Valdés Olmos RA,Haas RL,Hoebers FJ,van den Brekel MW,van Zandwijk N,Herk Mv,Verheij M

更新日期：2006-08-01 00:00:00

abstract：PURPOSE:The purpose of this study was to evaluate the impact of [18F]fluorodeoxy-D-glucose positron emission tomography (FDG-PET) on the primary staging of patients with small-cell lung cancer (SCLC). METHODS:FDG-PET was performed in 120 consecutive patients with SCLC during primary staging. In addition, brain examina...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Brink I,Schumacher T,Mix M,Ruhland S,Stoelben E,Digel W,Henke M,Ghanem N,Moser E,Nitzsche EU

更新日期：2004-12-01 00:00:00

abstract：PURPOSE:Dual-isotope simultaneous acquisition single-photon emission computed tomography (DISA SPECT) with 18F-fluorodeoxyglucose (FDG) and (99m)Tc-sestamibi appears attractive for the detection of viable myocardium because it permits simultaneous assessment of glucose utilisation and perfusion. Another potential benef...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Matsunari I,Kanayama S,Yoneyama T,Matsudaira M,Nakajima K,Taki J,Nekolla SG,Tonami N,Hisada K

更新日期：2005-02-01 00:00:00

abstract：PURPOSE:The aim of this study was to assess the accuracy of (18)F-fluorodeoxyglucose (FDG) positron emission tomography (PET)/CT to visualize lymph node metastases before the start of neoadjuvant chemotherapy and to determine how often the visualization is sufficiently prominent to allow monitoring of the axillary resp...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Straver ME,Aukema TS,Olmos RA,Rutgers EJ,Gilhuijs KG,Schot ME,Vogel WV,Peeters MJ

更新日期：2010-06-01 00:00:00

abstract：PURPOSE:This work aims to develop a methodology for automated atlas-guided analysis of small animal positron emission tomography (PET) data through deformable registration to an anatomical mouse model. METHODS:A non-rigid registration technique is used to put into correspondence relevant anatomical regions of rodent C...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Gutierrez DF,Zaidi H

更新日期：2012-11-01 00:00:00

abstract：PURPOSE:(131)Iodine metaiodobenzylguanidine ((131)I-MIBG) is a radiopharmaceutical used for scintigraphic localisation of phaeochromocytomas and paragangliomas. The experience with its therapeutic use is limited. We report our experience for the treatment of malignant phaeochromocytoma and paraganglioma. MATERIALS AND...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Gedik GK,Hoefnagel CA,Bais E,Olmos RA

更新日期：2008-04-01 00:00:00

abstract：:Synthetic macromolecules such as copolymers of N-(2-hydroxypropyl)methacrylamide (pHPMA) are potential carriers for the delivery of drugs owing to their ability to passively accumulate in solid tumours [enhanced permeation and retention (EPR) effect]. To gain further knowledge about the biodistribution and the cellula...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Kissel M,Peschke P,Subr V,Ulbrich K,Strunz AM,Kühnlein R,Debus J,Friedrich E

更新日期：2002-08-01 00:00:00

abstract：:The development of monofunctional DTPA derivatives has been a major breakthrough in the labelling of proteins or peptides with a variety of radiometals. Although this methodology is simple and useful for indium-111 labelling, the stability of these conjugates is too low for most therapeutic nuclides. Cyclic chelators,...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Béhé M,Becker W,Gotthardt M,Angerstein C,Behr TM

更新日期：2003-08-01 00:00:00