Detection of exosomal tyrosine receptor kinase B as a potential biomarker in ovarian cancer.

abstract：:Sterol 14α-Demethylase Cytochrome P450 (CYP51) protein involved in ergosterol biosynthesis pathways turn out to be a crucial target for the fungicidal compound. However, the recognition mechanism and dynamic behavior of CYP51 in wheat leaf rust pathogen, Puccinia triticina, is still obscure. Previously, a mutation at ...

journal_title：Journal of cellular biochemistry

authors： Pandey B,Sharma P

更新日期：2018-03-01 00:00:00

abstract：:Although several studies have shown that an induction of insulin-like growth factor (IGF) components occurs during hyperoxia-mediated lung injury, the role of these components in tissue repair is not well known. The present study aimed to elucidate the role of IGF system components in normal tissue remodeling. We used...

journal_title：Journal of cellular biochemistry

authors： Narasaraju TA,Chen H,Weng T,Bhaskaran M,Jin N,Chen J,Chen Z,Chinoy MR,Liu L

更新日期：2006-04-01 00:00:00

abstract：:The comet assay is one of the most widely used approaches for detecting DNA damage; generally, it provides information on the cell population-averaged level of DNA damage. Here, we present an automatic technique for easy measurement of standard comet characteristics and an annotation of the cell cycle phase of each co...

journal_title：Journal of cellular biochemistry

authors： Luzhin AV,Velichko AK,Razin SV,Kantidze OL

更新日期：2016-10-01 00:00:00

abstract：:Male pronucleus formation involves sperm nucleus decondensation and sperm chromatin remodeling. In sea urchins, male pronucleus decondensation was shown to be modulated by protein kinase C and a cdc2-like kinase sensitive to olomoucine in vitro assays. It was further demonstrated that olomoucine blocks SpH2B and SpH1 ...

journal_title：Journal of cellular biochemistry

authors： Monardes A,Iribarren C,Morin V,Bustos P,Puchi M,Imschenetzky M

更新日期：2005-10-01 00:00:00

abstract：:Thrombin increases the cytosolic Ca(2+) concentrations and induces NO production by activating proteinase-activated receptor 1 (PAR(1)) in vascular endothelial cells. The store-operated Ca(2+) influx is a major Ca(2+) influx pathway in non-excitable cells including endothelial cells and it has been reported to play a ...

journal_title：Journal of cellular biochemistry

authors： Hirano K,Hirano M,Hanada A

更新日期：2009-10-01 00:00:00

abstract：:Primary cultures fill a unique niche among the repertoire of in vitro model systems available to investigate the biology of the normal and malignant human prostate. This review summarizes some of the properties of primary cultures, with special emphasis on two questions: are primary cultures from adenocarcinomas reall...

journal_title：Journal of cellular biochemistry

authors： Peehl DM

更新日期：2004-01-01 00:00:00

abstract：:Osterix belongs to the SP gene family and is a core transcription factor responsible for osteoblast differentiation and bone formation. Activation of protein kinase A (PKA), a serine/threonine kinase, is essential for controlling bone formation and BMP-induced osteoblast differentiation. However, the relationship betw...

journal_title：Journal of cellular biochemistry

authors： He S,Choi YH,Choi JK,Yeo CY,Chun C,Lee KY

更新日期：2014-10-01 00:00:00

abstract：:CD38 is a type II transmembrane glycoprotein found mainly on the plasma membrane involved in the metabolism of cADPR and NAADP, two nucleotides with calcium mobilizing activity independent of inositol trisphosphate. Recent data report the presence of CD38 in different cellular compartments raising new questions about ...

journal_title：Journal of cellular biochemistry

authors： Trubiani O,Guarnieri S,Eleuterio E,Di Giuseppe F,Orciani M,Angelucci S,Di Primio R

更新日期：2008-03-01 00:00:00

abstract：:Lung cancer (LC) is the second common cancer for both women and men all over the world. Unfortunately, the number of LC deaths is increasing rapidly each year so early diagnosis of LC can be lifesaving. MicroRNAs are involved in multiple processes, such as cell differentiation, transcription, inflammation, proliferati...

journal_title：Journal of cellular biochemistry

authors： Asghariazar V,Sakhinia E,Mansoori B,Mohammadi A,Baradaran B

更新日期：2019-12-01 00:00:00

abstract：:Human prostate cancers (PCa) express great variability in their ability to metastasize to bone. The identification of molecules associated with aggressive phenotypes will help to define PCa subsets and will ultimately lead to better treatment strategies. The chemokine stromal-derived factor-1 (SDF-1 or CXCL12) and its...

journal_title：Journal of cellular biochemistry

authors： Sun YX,Wang J,Shelburne CE,Lopatin DE,Chinnaiyan AM,Rubin MA,Pienta KJ,Taichman RS

更新日期：2003-06-01 00:00:00

abstract：:The objective of this study was to evaluate the genotoxic and mutagenic effects of the toxins present in Lachesis muta muta's venom on human peripheral blood leukocytes and the protective potential of ascorbic acid on DNA fragmentation. The venom of L. muta muta was incubated in different concentrations (1, 2.5, 5, 7....

journal_title：Journal of cellular biochemistry

authors： Cardoso Trento MV,de Faria Eleutério MW,Silva Abreu T,Andrade Machado GH,Cesar PHS,Assaid Simão A,Marcussi S

更新日期：2019-03-01 00:00:00

abstract：:This study aims to investigate the combined effects of Pulsed wave low-level laser therapy (PW LLLT) and human bone marrow mesenchymal stem cell-conditioned medium (hBM-MSC-CM) on the microbial flora and tensiometrical properties of an infected wound model with methicillin-resistant staphylococcal aureus (MRSA) in an ...

journal_title：Journal of cellular biochemistry

authors： Kouhkheil R,Fridoni M,Piryaei A,Taheri S,Chirani AS,Anarkooli IJ,Nejatbakhsh R,Shafikhani S,Schuger LA,Reddy VB,Ghoreishi SK,Jalalifirouzkouhi R,Chien S,Bayat M

更新日期：2018-07-01 00:00:00

abstract：:Members of the transforming growth factor-β (TGF-β) family function through Smad-dependent and Smad-independent pathways. The Smad-dependent pathway is stimulated through the phosphorylation of receptor-regulated Smad (R-Smad) and inhibited through the dephosphorylation of R-Smad or the gene induction of inhibitory Sm...

journal_title：Journal of cellular biochemistry

authors： Katakawa Y,Funaba M,Murakami M

更新日期：2016-08-01 00:00:00

abstract：:HSP90 chaperones are transducer proteins of many signaling pathways in cells. Using a highly specific inhibitor, geldanamycin (GA), an increasing number of the HSP90 client proteins have been identified. Nevertheless, there is little information on the differential transactivation of the two isoforms of the hsp90 gene...

journal_title：Journal of cellular biochemistry

authors： Chao CC,Sun FC,Wang CH,Lo CW,Chang YS,Chang KC,Chang MD,Lai YK

更新日期：2008-07-01 00:00:00

abstract：:Obesity and aging lead to abnormal transforming growth factor-β1 (TGF-β1) signaling in the hypothalamus, triggering the imbalance on glucose metabolism and energy homeostasis. Here, we determine the effect of acute exercise on TGF-β1 expression in the hypothalamus of two models of obesity in mice. The bioinformatics a...

journal_title：Journal of cellular biochemistry

authors： Silva VRR,Lenhare L,Katashima CK,Morari J,M-Assis A,Gaspar RS,da Silva ASR,Moura LP,Pauli JR,Cintra DE,Velloso LA,Ropelle ER

更新日期：2019-10-01 00:00:00

abstract：:The migration of endothelial cells (ECs) plays an important role in vascular remodeling and regeneration. EC migration can be regulated by different mechanisms such as chemotaxis, haptotaxis, and mechanotaxis. This review will focus on fluid shear stress-induced mechanotransduction during EC migration. EC migration an...

journal_title：Journal of cellular biochemistry

authors： Li S,Huang NF,Hsu S

更新日期：2005-12-15 00:00:00

abstract：:The tetrazolium salt 3(4,5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT) is reduced to formazan by the succinate dehydrogenase system of active mitochondria, and hence, specifically used to assay for the viable cells, such as measurement of cell proliferation, cytotoxicity, and cell number. However, in ...

journal_title：Journal of cellular biochemistry

authors： Chakrabarti R,Kundu S,Kumar S,Chakrabarti R

更新日期：2000-09-18 00:00:00

abstract：:Arsenic trioxide (ATO) is a first-line anti-cancer agent for acute promyelocytic leukemia, and induces apoptosis in other solid cancer cell lines including breast cancer cells. However, as with arsenites found in drinking water and used as raw materials for wood preservatives, insecticides, and herbicides, low doses o...

journal_title：Journal of cellular biochemistry

authors： Liu Y,Hock JM,Sullivan C,Fang G,Cox AJ,Davis KT,Davis BH,Li X

更新日期：2010-12-15 00:00:00

abstract：:In this study, we purpose to investigate a novel five-gene signature for predicting the prognosis of patients with laryngeal cancer. The laryngeal cancer datasets were obtained from The Cancer Genome Atlas (TCGA). Both univariate and multivariate Cox regression analysis was applied to screening for prognostic differen...

journal_title：Journal of cellular biochemistry

authors： Zhang G,Fan E,Yue G,Zhong Q,Shuai Y,Wu M,Feng G,Chen Q,Gou X

更新日期：2019-10-31 00:00:00

abstract：:Pancreatic ductal adenocarcinoma (PDAC) remains a huge challenge due to its high mortality and morbidity; gene therapy might be a promising treatment for PDAC. The critical role of Wnt-signaling pathway in cancer pathogenesis has been widely recognized; cyclin-dependent kinase 14 (CDK14, PFTK1)-induced low-density lip...

journal_title：Journal of cellular biochemistry

authors： Sun Y,Zhu Q,Yang W,Shan Y,Yu Z,Zhang Q,Wu H

更新日期：2019-03-01 00:00:00

abstract：:Transcription of the heat shock genes is regulated by the activation of the heat shock transcription factor (HSF-1). After heat shock, HSF-1 forms oligomers and binds to the heat shock element (HSE), which consists of several repeats of NGAAN located in the promoter region of the heat shock genes. HSF-1 is then phosph...

journal_title：Journal of cellular biochemistry

authors： Mivechi NF,Shi XY,Hahn GM

更新日期：1995-10-01 00:00:00

abstract：:Formyl peptide receptors (FPRs) are a family of classical chemoattractant receptors. Although FPRs are mainly expressed in phagocytic innate immune cells including monocytes/macrophages and neutrophils, recent reports demonstrated that additional different cell types such as T-lymphocytes and several non-immune cells ...

journal_title：Journal of cellular biochemistry

authors： Lee HY,Lee M,Bae YS

更新日期：2017-06-01 00:00:00

abstract：:Idiopathic pulmonary fibrosis (IPF), characterized by irreversible scarring and progressive destruction of the lung tissue, is one of the most common types of idiopathic interstitial pneumonia worldwide. However, there are no reliable candidates for curative therapies. Hence, elucidation of the mechanisms of IPF genes...

journal_title：Journal of cellular biochemistry

authors： Wang H,Xie Q,Ou-Yang W,Zhang M

更新日期：2018-12-02 00:00:00

abstract：:Choline-deficiency causes liver cells to die by apoptosis, and it has not been clear whether the effects of choline-deficiency are mediated by methyl-deficiency or by lack of choline moieties. SV40 immortalized CWSV-1 hepatocytes were cultivated in media that were choline-sufficient, choline-deficient, choline-deficie...

journal_title：Journal of cellular biochemistry

authors： Shin OH,Mar MH,Albright CD,Citarella MT,da Costa KA,Zeisel SH

更新日期：1997-02-01 00:00:00

abstract：:We have purified and characterized a collagenase/gelatinase activity expressed during sea urchin embryonic development. The native molecular mass was determined to be 160 kDa, while gelatin substrate gel zymography revealed an active species of 41 kDa, suggesting that the native enzyme is a tetramer of active subunits...

journal_title：Journal of cellular biochemistry

authors： Mayne J,Robinson JJ

更新日期：1998-12-15 00:00:00

abstract：:In response to tissue injury connective tissue synthesis occurs either normally or abnormally, which is mediated by transforming growth factor-beta (TGF-beta) and other growth factors. This article will be primarily concerned with the response of injured tissues at the gene level of Type I procollagen synthesis in res...

journal_title：Journal of cellular biochemistry

authors： Cutroneo KR

更新日期：2003-09-01 00:00:00

abstract：:Telomeres are TTAGGG repetitive motifs found at the ends of vertebrate chromosomes. In humans, telomeres are protected by shelterin, a complex of six proteins (de Lange [2005] Genes Dev. 19: 2100-2110). Since (Müller [1938] Collecting Net. 13: 181-198; McClintock [1941] Genetics 26: 234-282), their function in maintai...

journal_title：Journal of cellular biochemistry

authors： Mai S,Garini Y

更新日期：2006-04-01 00:00:00

abstract：:Muscular dystrophies are characterized by continuous cycles of degeneration and regeneration that result in extensive fibrosis and a progressive diminution of muscle mass. Cell surface heparan sulfate proteoglycans are found almost ubiquitously on the surface and in the extracellular matrix (ECM) of mammalian cells. T...

journal_title：Journal of cellular biochemistry

authors： Alvarez K,Fadic R,Brandan E

更新日期：2002-01-01 00:00:00

abstract：:Myogenesis involves myoblast proliferation and differentiation to myocytes, followed by fusion and hypertrophy to form myotubes during muscle development. Increasing evidence showed that microRNAs (miRNAs) play important roles in the regulation of myogenesis. We have previously revealed that miR-34b is steadily increa...

journal_title：Journal of cellular biochemistry

authors： Tang Z,Qiu H,Luo L,Liu N,Zhong J,Kang K,Gou D

更新日期：2017-12-01 00:00:00

abstract：:As an important tumor suppressor, programmed cell death 4 (PDCD4) influences transcription and translation of multiple genes, and modulates different signal transduction pathways. However, the upstream regulation of this gene is largely unknown. In this study, we found that microRNA-182 (miRNA-182, miR-182) was upregu...

journal_title：Journal of cellular biochemistry

authors： Wang YQ,Guo RD,Guo RM,Sheng W,Yin LR

更新日期：2013-07-01 00:00:00