Therapy for Mycobacterium kansasii Infection: Beyond 2018.

abstract：:The dearth of new antibiotics in the face of widespread antimicrobial resistance makes developing innovative strategies for discovering new antibiotics critical for the future management of infectious disease. Understanding the genetics and evolution of antibiotic producers will help guide the discovery and bioenginee...

journal_title：Frontiers in microbiology

authors： Stulberg ER,Lozano GL,Morin JB,Park H,Baraban EG,Mlot C,Heffelfinger C,Phillips GM,Rush JS,Phillips AJ,Broderick NA,Thomas MG,Stabb EV,Handelsman J

更新日期：2016-05-03 00:00:00

abstract：:Interactions between plants and microbes can affect ecosystem functions, and many studies have demonstrated that plant properties influence mutualistic microorganisms. Here, high-throughput sequencing was used to investigate rhizosphere and phyllosphere fungal communities during different plant development stages. Res...

journal_title：Frontiers in microbiology

authors： Jia T,Yao Y,Guo T,Wang R,Chai B

更新日期：2020-09-29 00:00:00

abstract：:Most microbes can produce surface-associated or suspended aggregates called biofilms, which are encased within a biopolymer-rich matrix. The biofilm matrix provides structural integrity to the aggregates and shields the resident cells against environmental stressors, including antibiotic treatment. Microscopy permits ...

journal_title：Frontiers in microbiology

authors： Reichhardt C,Parsek MR

更新日期：2019-04-02 00:00:00

abstract：:Emerging evidence suggests that antibodies against merozoite proteins involved in Plasmodium falciparum invasion into the red blood cell (RBC) play an important role in clinical immunity to malaria. The protein family of parasite antigens known as P. falciparum reticulocyte binding protein-like homolog (PfRh) is requi...

journal_title：Frontiers in microbiology

authors： Chiu CY,Healer J,Thompson JK,Chen L,Kaul A,Savergave L,Raghuwanshi A,Li Wai Suen CS,Siba PM,Schofield L,Mueller I,Cowman AF,Hansen DS

更新日期：2014-06-30 00:00:00

abstract：:Deep-sea hydrothermal vent environments are characterized by high hydrostatic pressure and sharp temperature and chemical gradients. Horizontal gene transfer is thought to play an important role in the microbial adaptation to such an extreme environment. In this study, a 21.4-kb DNA fragment was identified as a genomi...

journal_title：Frontiers in microbiology

authors： Li Z,Li X,Xiao X,Xu J

更新日期：2016-11-29 00:00:00

abstract：:Dynamic Light Scattering (DLS), Small Angle X-ray Scattering (SAXS) and Transmission Electron Microscopy (TEM) are physical techniques widely employed to characterize the morphology and the structure of vesicles such as liposomes or human extracellular vesicles (exosomes). Bacterial extracellular vesicles are similar ...

journal_title：Frontiers in microbiology

authors： Sarra A,Celluzzi A,Bruno SP,Ricci C,Sennato S,Ortore MG,Casciardi S,Del Chierico F,Postorino P,Bordi F,Masotti A

更新日期：2020-02-27 00:00:00

abstract：:Trachomatous trichiasis (TT) caused by repeated or chronic ocular infection with Chlamydia trachomatis is the result of a pro-fibrotic ocular immune response. At the conjunctiva, the increased expression of both inflammatory (IL1B, TNF) and regulatory cytokines (IL10) have been associated with adverse clinical outcome...

journal_title：Frontiers in microbiology

authors： Gall A,Horowitz A,Joof H,Natividad A,Tetteh K,Riley E,Bailey RL,Mabey DC,Holland MJ

更新日期：2011-02-10 00:00:00

abstract：:Manipulation of cell cycle is a commonly employed strategy of viruses for achieving a favorable cellular environment during infection. Kaposi's sarcoma-associated herpesvirus (KSHV), the primary etiological agent of several human malignancies including Kaposi's sarcoma, and primary effusion lymphoma, encodes several o...

journal_title：Frontiers in microbiology

authors： Wei F,Gan J,Wang C,Zhu C,Cai Q

更新日期：2016-03-30 00:00:00

abstract：:The rumen and the hindgut represent two different fermentation organs in herbivorous mammals, with the former producing much more methane than the latter. The objective of this study was to elucidate the microbial underpinning of such differential methane outputs between these two digestive organs. Methane production ...

journal_title：Frontiers in microbiology

authors： Mi L,Yang B,Hu X,Luo Y,Liu J,Yu Z,Wang J

更新日期：2018-03-27 00:00:00

abstract：:Ecological significance of trees growing in urban and peri-urban settings is likely to increase in future land-use regimes, calling for better understanding of their role as potential reservoirs or stepping stones for associated biodiversity. We studied the diversity of fungal endophytes in woody tissues of asymptomat...

journal_title：Frontiers in microbiology

authors： Agostinelli M,Cleary M,Martín JA,Albrectsen BR,Witzell J

更新日期：2018-08-03 00:00:00

abstract：:Ecological understandings of soil bacterial community succession and assembly mechanism along elevational gradients in mountains remain not well understood. Here, by employing the high-throughput sequencing technique, we systematically examined soil bacterial diversity patterns, the driving factors, and community asse...

journal_title：Frontiers in microbiology

authors： Li J,Shen Z,Li C,Kou Y,Wang Y,Tu B,Zhang S,Li X

更新日期：2018-03-27 00:00:00

abstract：:Long non-coding RNAs (lncRNAs) regulate gene expression at the epigenetic, transcriptional, or posttranscriptional level by interacting with protein, DNA, and RNA. Emerging evidence suggests that various lncRNAs are abnormally expressed and play indispensable roles in virus-triggered cancers. Besides, a growing number...

journal_title：Frontiers in microbiology

authors： Liu W,Zhang Y,Luo B

更新日期：2021-01-15 00:00:00

abstract：:Sulfate-reducing bacteria (SRB) and sulfur-oxidizing bacteria (SOB) have been studied extensively in marine sediments because of their vital roles in both sulfur and carbon cycles, but the available information regarding the highly diverse SRB and SOB communities is not comprehensive. High-throughput sequencing of fun...

journal_title：Frontiers in microbiology

authors： Zhang Y,Wang X,Zhen Y,Mi T,He H,Yu Z

更新日期：2017-11-07 00:00:00

abstract：:Objectives: Sequence type 1193 is emerging as a new, virulent and resistant lineage among fluoroquinolone resistant Escherichia coli (FQrE. coli). In this study, we investigated the prevalence and molecular characteristics of this clone isolated from a Chinese university hospital. Methods: 73 phylogenetic group B2-FQr...

journal_title：Frontiers in microbiology

authors： Wu J,Lan F,Lu Y,He Q,Li B

更新日期：2017-11-21 00:00:00

abstract：:The discovery of anaerobic ammonia oxidation (anammox) expanded our knowledge on the microbial nitrogen cycle. Previous studies report that anammox bacteria are distributed in a wide range of habitats and plays significant roles in the global nitrogen cycle. However, most studies focus only on individual ecosystems or...

journal_title：Frontiers in microbiology

authors： Wang Y,Xu L,Wang S,Ye F,Zhu G

更新日期：2019-11-12 00:00:00

abstract：:In bacteria, the GntR family is a widespread family of transcription factors responsible for the regulation of a myriad of biological processes. In contrast, despite their occurrence in archaea only a little information is available on the function of GntR-like transcription factors in this domain of life. The thermoa...

journal_title：Frontiers in microbiology

authors： Lemmens L,Tilleman L,De Koning E,Valegård K,Lindås AC,Van Nieuwerburgh F,Maes D,Peeters E

更新日期：2019-09-10 00:00:00

abstract：:Soil microbial diversity is huge and a few grams of soil contain more bacterial taxa than there are bird species on Earth. This high diversity often makes predicting the responses of soil bacteria to environmental change intractable and restricts our capacity to predict the responses of soil functions to global change...

journal_title：Frontiers in microbiology

authors： Le Roux X,Bouskill NJ,Niboyet A,Barthes L,Dijkstra P,Field CB,Hungate BA,Lerondelle C,Pommier T,Tang J,Terada A,Tourna M,Poly F

更新日期：2016-05-17 00:00:00

abstract：:The Gram negative bacterium Yersinia pestis can infect humans by multiple routes to cause plague. Three plague pandemics have occurred and Y. pestis has been linked to biowarfare in the past. The continued risk of plague as a bioweapon has prompted increased research to understand Y. pestis pathogenesis and develop ne...

journal_title：Frontiers in microbiology

authors： Lawrenz MB

更新日期：2010-11-04 00:00:00

abstract：:Dengue virus (DENV) infection causes several diseases ranging from dengue fever to life-threatening dengue hemorrhagic fever and dengue shock syndrome characterized by endothelial dysfunction, vascular leakage, and shock. Here, we identify a potential mechanism by which DENV induces tissue injury and vascular leakage ...

journal_title：Frontiers in microbiology

authors： Pan P,Zhang Q,Liu W,Wang W,Yu Z,Lao Z,Zhang W,Shen M,Wan P,Xiao F,Shereen MA,Zhang W,Tan Q,Liu Y,Liu X,Wu K,Liu Y,Li G,Wu J

更新日期：2019-11-22 00:00:00

abstract：:Reversible protein phosphorylation, regulated by protein kinases and phosphatases, mediates a switch between protein activity and cellular pathways that contribute to a large number of cellular processes. The Mycobacterium tuberculosis genome encodes 11 Serine/Threonine kinases (STPKs) which show close homology to euk...

journal_title：Frontiers in microbiology

authors： Fortuin S,Tomazella GG,Nagaraj N,Sampson SL,Gey van Pittius NC,Soares NC,Wiker HG,de Souza GA,Warren RM

更新日期：2015-02-10 00:00:00

abstract：:Bacteriophage endolysins and bacterial exolysins are capable of enzymatic degradation of the cell wall peptidoglycan layer and thus show promise as a new class of antimicrobials. Both exolysins and endolysins often consist of different modules, which are responsible for enzymatic functions and cell wall binding, respe...

journal_title：Frontiers in microbiology

authors： Hjelm LC,Nilvebrant J,Nygren PÅ,Nilsson AS,Seijsing J

更新日期：2019-03-22 00:00:00

abstract：:We demonstrate that the antimicrobial peptide, melittin, is effective alone and in combination with the aminoglycosides tobramycin to kill Pseudomonas aeruginosa growing as biofilms both in vitro and in vivo. Melittin and tobramycin show enhanced in vitro activity in combination at micromolar concentrations, resulting...

journal_title：Frontiers in microbiology

authors： Maiden MM,Zachos MP,Waters CM

更新日期：2019-06-20 00:00:00

abstract：:Formate dehydrogenase H (FDH-H) and [NiFe]-hydrogenase 3 (Hyd-3) form the catalytic components of the hydrogen-producing formate hydrogenlyase (FHL) complex, which disproportionates formate to H2 and CO2 during mixed acid fermentation in enterobacteria. FHL comprises minimally seven proteins and little is understood a...

journal_title：Frontiers in microbiology

authors： Pinske C

更新日期：2018-06-11 00:00:00

abstract：:Quorum sensing (QS) is a process enabling a bacterial population to communicate via small molecules called autoinducers (AIs). This intercellular communication process allows single cells to synchronize their behavior within a population. The marine bacterium Vibrio harveyi ATCC BAA-1116 channels the information of th...

journal_title：Frontiers in microbiology

authors： Lorenz N,Shin JY,Jung K

更新日期：2017-04-18 00:00:00

abstract：:Lysine-porphyrin conjugate 4i has potent photosensitive antibacterial effect on clinical isolated bacterial strains such as Methicillin-resistant Staphylococcus aureus (MRSA), Escherichia coli, and Pseudomonas aeruginosa. The mechanism of photodynamic antibacterial chemotherapy of 4i (4i-PACT) in vitro and the treatme...

journal_title：Frontiers in microbiology

authors： Xu Z,Gao Y,Meng S,Yang B,Pang L,Wang C,Liu T

更新日期：2016-03-02 00:00:00

abstract：:The metataxonomic approach combining 16S rRNA gene amplicon sequencing using the PacBio Technology with the application of the operational phylogenetic unit (OPU) approach, has been used to analyze the fecal microbial composition of the high-altitude and herbivorous Tibetan antelopes. The fecal samples of the antelope...

journal_title：Frontiers in microbiology

authors： Bai X,Lu S,Yang J,Jin D,Pu J,Díaz Moyá S,Xiong Y,Rossello-Mora R,Xu J

更新日期：2018-09-28 00:00:00

abstract：:Toxoplasma gondii rhoptry proteins (TgROPs) are the major targets as key molecules for immunodiagnosis as well as immunoprophylaxis because of their initial presentation to the host immune system. In this work, it was aimed at evaluating the protection effect of TgROP21 DNA vaccine on experimental mice subjected to T....

journal_title：Frontiers in microbiology

authors： Zhang Z,Li Y,Wang M,Xie Q,Li P,Zuo S,Kong L,Wang C,Wang S

更新日期：2018-05-08 00:00:00

abstract：:In the industry of fermented food and beverages, yeast cultures are often selected and standardized in order to ensure a better control of fermentation and a more stable product over time. Several studies have shown that the organoleptic characteristics of fermented products reflect geographic variations of the microb...

journal_title：Frontiers in microbiology

authors： Di Paola M,Meriggi N,Cavalieri D

更新日期：2020-10-29 00:00:00

abstract：:Studying the pathobiology of the fungus Aspergillus fumigatus has gained a lot of attention in recent years. This is due to the fact that this fungus is a human pathogen that can cause severe diseases, like invasive pulmonary aspergillosis in immunocompromised patients. Because alveolar macrophages belong to the first...

journal_title：Frontiers in microbiology

authors： Kraibooj K,Schoeler H,Svensson CM,Brakhage AA,Figge MT

更新日期：2015-06-09 00:00:00

abstract：:Internal bacterial concentration of Mg2+, the most abundant divalent cation in living cells, is estimated to be in the single millimolar range. However, many bacteria will thrive in media with only micromolars of Mg2+, by using a range of intensely studied and highly efficient import mechanisms, as well as in media wi...

journal_title：Frontiers in microbiology

authors： Armitano J,Redder P,Guimarães VA,Linder P

更新日期：2016-11-25 00:00:00