Model systems to study plague pathogenesis and develop new therapeutics.

abstract：:Prostatitis has various etiology including bacterial infection and dysregulated immunity; some of its forms remain a serious therapeutic challenge. Inflammation occurs in all forms of this disorder and is proposed to predispose to the development of prostate cancer (PC). There are reports that phage therapy is effecti...

journal_title：Frontiers in microbiology

authors： Górski A,Jończyk-Matysiak E,Łusiak-Szelachowska M,Międzybrodzki R,Weber-Dąbrowska B,Borysowski J,Letkiewicz S,Bagińska N,Sfanos KS

更新日期：2018-06-29 00:00:00

abstract：:Cheese microbiota contribute significantly to the final characteristics of cheeses due to the growth and interaction between cheese microorganisms during processing and ripening. For raw milk cheeses, such as Parmigiano Reggiano (PR), the microbiota derive from the raw milk itself, the dairy environment, and the start...

journal_title：Frontiers in microbiology

authors： Bottari B,Levante A,Bancalari E,Sforza S,Bottesini C,Prandi B,De Filippis F,Ercolini D,Nocetti M,Gatti M

更新日期：2020-10-02 00:00:00

abstract：:Incorporation of self-derived CRISPR DNA protospacers in Campylobacter jejuni PT14 occurs in the presence of bacteriophages encoding a CRISPR-like Cas4 protein. This phenomenon was evident in carrier state infections where both bacteriophages and host are maintained for seemingly indefinite periods as stable populatio...

journal_title：Frontiers in microbiology

authors： Hooton SP,Brathwaite KJ,Connerton IF

更新日期：2016-03-23 00:00:00

abstract：:Extraintestinal pathogenic Escherichia coli (ExPEC) that causes extraintestinal infections often harbor plasmids encoding fitness traits such as resistance and virulence determinants that are of clinical importance. We determined the complete nucleotide sequence of plasmid pEC302/04 from a multidrug-resistant E. coli ...

journal_title：Frontiers in microbiology

authors： Ho WS,Yap KP,Yeo CC,Rajasekaram G,Thong KL

更新日期：2016-01-11 00:00:00

abstract：:Clostridium difficile PCR ribotype (RT) 014 is well-established in both human and porcine populations in Australia, raising the possibility that C. difficile infection (CDI) may have a zoonotic or foodborne etiology. Here, whole genome sequencing and high-resolution core genome phylogenetics were performed on a contem...

journal_title：Frontiers in microbiology

authors： Knight DR,Squire MM,Collins DA,Riley TV

更新日期：2017-01-11 00:00:00

abstract：:Conflict and cooperation between bacterial species drive the composition and function of microbial communities. Stability of these emergent properties will be influenced by the degree to which species' interactions are robust to genetic perturbations. We use genome-scale metabolic modeling to computationally analyze t...

journal_title：Frontiers in microbiology

authors： Chubiz LM,Granger BR,Segrè D,Harcombe WR

更新日期：2015-04-14 00:00:00

abstract：:Whole-genome sequencing (WGS) is the method of choice for bacterial subtyping and it is rapidly replacing the more traditional methods such as pulsed-field gel electrophoresis (PFGE). Here we used the high-resolution core genome single nucleotide variant (cgSNV) typing method to characterize clinical and food from Sal...

journal_title：Frontiers in microbiology

authors： Yousfi K,Usongo V,Berry C,Khan RH,Tremblay DM,Moineau S,Mulvey MR,Doualla-Bell F,Fournier E,Nadon C,Goodridge L,Bekal S

更新日期：2020-06-17 00:00:00

abstract：:Aflatoxins (AF) are highly detrimental to human and animal health. We recently demonstrated that the Aspergillus flavus caleosin, AfPXG, had peroxygenase activity and mediated fungal development and AF accumulation. We now report the characterization of an AfPXG-deficient line using reference strain NRRL3357. The resu...

journal_title：Frontiers in microbiology

authors： Hanano A,Alkara M,Almousally I,Shaban M,Rahman F,Hassan M,Murphy DJ

更新日期：2018-02-06 00:00:00

abstract：:Much of the mitogenome variation observed in fungal lineages seems driven by mobile genetic elements (MGEs), which have invaded their genomes throughout evolution. The variation in the distribution and nucleotide diversity of these elements appears to be the main distinction between different fungal taxa, making them ...

journal_title：Frontiers in microbiology

authors： Kulik T,Brankovics B,van Diepeningen AD,Bilska K,Żelechowski M,Myszczyński K,Molcan T,Stakheev A,Stenglein S,Beyer M,Pasquali M,Sawicki J,Wyrȩbek J,Baturo-Cieśniewska A

更新日期：2020-05-25 00:00:00

abstract：:The seasonal melting of ice entombed cryoconite holes on McMurdo Dry Valley glaciers provides oases for life in the harsh environmental conditions of the polar desert where surface air temperatures only occasionally exceed 0°C during the Austral summer. Here we follow temporal changes in cryoconite hole biogeochemistr...

journal_title：Frontiers in microbiology

authors： Telling J,Anesio AM,Tranter M,Fountain AG,Nylen T,Hawkings J,Singh VB,Kaur P,Musilova M,Wadham JL

更新日期：2014-12-11 00:00:00

abstract：:The golden orb-weaver spider Nephila clavipes, known for its sexual size dimorphism, is abundant and widespread in the New World. The first annotated genome of orb-weaver spiders, exploring N. clavipes, has recently been reported. The study, focused primarily on the diversity of silk specific genes, shed light into th...

journal_title：Frontiers in microbiology

authors： Debat HJ

更新日期：2017-10-25 00:00:00

abstract：:Paracoccidioidomycosis (PCM) is the most prevalent endemic mycosis in Latin America. The disease is caused by fungi of the genus Paracoccidioides and mainly affects low-income rural workers after inhalation of fungal conidia suspended in the air. The current arsenal of chemotherapeutic agents requires long-term admini...

journal_title：Frontiers in microbiology

authors： de Oliveira AA,Neves BJ,Silva LDC,Soares CMA,Andrade CH,Pereira M

更新日期：2019-06-12 00:00:00

abstract：:MicroRNAs (miRNAs) have been demonstrated for their involvement in virus biology and pathogenesis, including functioning as key determinants of virally-induced cancers. As an important oncogenic α-herpesvirus affecting poultry health, Marek's disease virus serotype 1 [Gallid alphaherpesvirus 2 (GaHV-2)] induces rapid-...

journal_title：Frontiers in microbiology

authors： Zhu ZJ,Teng M,Li HZ,Zheng LP,Liu JL,Chai SJ,Yao YX,Nair V,Zhang GP,Luo J

更新日期：2020-11-03 00:00:00

abstract：:Diatoms are a dominant group of eukaryotic phytoplankton that contribute substantially to global primary production and the cycling of important elements such as carbon and nitrogen. Heterotrophic bacteria, including members of the gammaproteobacteria, are commonly associated with diatom populations and may rely on th...

journal_title：Frontiers in microbiology

authors： Diner RE,Schwenck SM,McCrow JP,Zheng H,Allen AE

更新日期：2016-06-09 00:00:00

abstract：:An ideal DNA polymerase for chain-terminating DNA sequencing should possess the following features: (1) incorporate dideoxy- and other modified nucleotides at an efficiency similar to that of the cognate deoxynucleotides; (2) high processivity; (3) high fidelity in the absence of proofreading/exonuclease activity; and...

journal_title：Frontiers in microbiology

authors： Zhu B

更新日期：2014-04-16 00:00:00

abstract：:Cyanobacteria are major contributors to global biogeochemical cycles. The genetic diversity among Cyanobacteria enables them to thrive across many habitats, although only a few studies have analyzed the association of phylogenomic clades to specific environmental niches. In this study, we adopted an ecogenomics strate...

journal_title：Frontiers in microbiology

authors： Walter JM,Coutinho FH,Dutilh BE,Swings J,Thompson FL,Thompson CC

更新日期：2017-11-14 00:00:00

abstract：:Respiratory viruses such as parainfluenza virus (PIV) in individuals with certain genetic predispositions in early life are associated with the induction of wheezing, which can progress to the development of asthma. It has been suggested that aberrant production of various cytokines due to viral infection are associat...

journal_title：Frontiers in microbiology

authors： Yoshizumi M,Kimura H,Okayama Y,Nishina A,Noda M,Tsukagoshi H,Kozawa K,Kurabayashi M

更新日期：2010-11-15 00:00:00

abstract：:Nutrient availability and ratios can play an important role in shaping microbial communities of freshwater ecosystems. The Cuatro Ciénegas Basin (CCB) in Mexico is a desert oasis where, perhaps paradoxically, high microbial diversity coincides with extreme oligotrophy. To better understand the effects of nutrients on ...

journal_title：Frontiers in microbiology

authors： Lee ZM,Poret-Peterson AT,Siefert JL,Kaul D,Moustafa A,Allen AE,Dupont CL,Eguiarte LE,Souza V,Elser JJ

更新日期：2017-05-30 00:00:00

abstract：:There is a concerted understanding of the accumulation of soil pathogens as the major driving factor of negative plant-soil feedback (NPSF). However, our knowledge of the connection between plant growth, pathogen build-up and soil microbiome assemblage is limited. In this study, significant negative feedback between t...

journal_title：Frontiers in microbiology

authors： Luo L,Guo C,Wang L,Zhang J,Deng L,Luo K,Huang H,Liu Y,Mei X,Zhu S,Yang M

更新日期：2019-07-26 00:00:00

abstract：:Many bacteria produce cytolytic toxins that target host cells or other competing microbes. It is well known that environmental factors control toxin expression, however, recent work suggests that some bacteria manipulate the fold of these protein toxins to control their function. The β-sheet rich amyloid fold is a hig...

journal_title：Frontiers in microbiology

authors： Syed AK,Boles BR

更新日期：2014-08-01 00:00:00

abstract：:Lycium barbarum is a boxthorn that produces the goji berries. The aim of the current study was to evaluate the proliferative effect of L. barbarum polysaccharides (LBP) on probiotics. LBP was extracted from goji berries and its monosaccharide composition characterized by gas chromatography (GC). The LBP extract contai...

journal_title：Frontiers in microbiology

authors： Zhou F,Jiang X,Wang T,Zhang B,Zhao H

更新日期：2018-05-18 00:00:00

abstract：:The worldwide dissemination of carbapenemase-producing Enterobacteriaceae (CPE) has become a major therapeutic concern in clinical settings. Enterobacter cloacae is a major pathogen that causes serious hospital-acquired infections. We investigated the clinical characteristics and molecular mechanisms of the first IMP-...

journal_title：Frontiers in microbiology

authors： Lee JH,Bae IK,Lee CH,Jeong S

更新日期：2017-11-28 00:00:00

abstract：:The claudin family protein Fig1 is a unique fungal protein that is involved in pheromone-induced calcium influx and membrane fusion during the mating of Saccharomyces cerevisiae and Candida albicans. Whether and how Fig1 regulates Ca2+ homeostasis in response to extracellular stimuli is poorly understood. Previously, ...

journal_title：Frontiers in microbiology

authors： Qian H,Chen Q,Zhang S,Lu L

更新日期：2018-05-15 00:00:00

abstract：:Cyclic lipodepsipeptides produced by Pseudomonas spp. (Ps-CLPs) are biosurfactants that constitute a diverse class of versatile bioactive natural compounds with promising application potential. While chemically diverse, they obey a common structural blue-print, allowing the definition of 14 distinct groups with multip...

journal_title：Frontiers in microbiology

authors： Geudens N,Martins JC

更新日期：2018-08-14 00:00:00

abstract：:Functional oligosaccharides, known as prebiotics, and ordinary dietary fiber have important roles in modulating the structure of intestinal microbiota. To investigate their effects on the intestinal microecosystem, three kinds of diets containing different prebiotics were used to feed mice for 3 weeks, as follows: GI ...

journal_title：Frontiers in microbiology

authors： Cheng W,Lu J,Li B,Lin W,Zhang Z,Wei X,Sun C,Chi M,Bi W,Yang B,Jiang A,Yuan J

更新日期：2017-09-20 00:00:00

abstract：:Genes that are constitutively expressed across multiple environmental stimuli are crucial to quantifying differentially expressed genes, particularly when employing quantitative reverse transcriptase polymerase chain reaction (RT-qPCR) assays. However, the identification of these potential reference genes in non-model...

journal_title：Frontiers in microbiology

authors： Alexander H,Jenkins BD,Rynearson TA,Saito MA,Mercier ML,Dyhrman ST

更新日期：2012-11-09 00:00:00

abstract：:H5N1 is a highly pathogenic influenza A virus (IAV) and poses a major threat to the public health. The nucleoprotein (NP) has a multiple functions during the viral life cycle, however, the precise role of NP mutants in viral replication and pathogenicity is not completely understood. Here, we attempted to identify fiv...

journal_title：Frontiers in microbiology

authors： Chen L,Wang C,Luo J,Li M,Liu H,Zhao N,Huang J,Zhu X,Ma G,Yuan G,He H

更新日期：2017-07-11 00:00:00

abstract：:Geological CO2 sequestration in unmineable subsurface oil/gas fields and coal formations has been proposed as a means of reducing anthropogenic greenhouse gasses in the atmosphere. However, the feasibility of injecting CO2 into subsurface depends upon a variety of geological and economic conditions, and the ecological...

journal_title：Frontiers in microbiology

authors： Ohtomo Y,Ijiri A,Ikegawa Y,Tsutsumi M,Imachi H,Uramoto G,Hoshino T,Morono Y,Sakai S,Saito Y,Tanikawa W,Hirose T,Inagaki F

更新日期：2013-12-02 00:00:00

abstract：:Bacterial host tropism is a primary determinant of the range of host organisms they can infect. Salmonella serotypes are differentiated into host-restricted and host-adapted specialists, and host-unrestricted generalists. In order to elucidate the underlying molecular mechanisms of host specificity in Salmonella infec...

journal_title：Frontiers in microbiology

authors： Kolenda R,Burdukiewicz M,Schiebel J,Rödiger S,Sauer L,Szabo I,Orłowska A,Weinreich J,Nitschke J,Böhm A,Gerber U,Roggenbuck D,Schierack P

更新日期：2018-08-22 00:00:00

abstract：:The rapid detection of foodborne microbial pathogens contaminating fresh fruits and vegetables during the intervening period between harvest and consumption could revolutionize microbial quality assurance of food usually consumed raw and those with a limited shelf life. We have developed a sensitive, shotgun whole gen...

journal_title：Frontiers in microbiology

authors： Ogunremi D,Dupras AA,Naushad S,Gao R,Duceppe MO,Omidi K,Márquez IG,Huang H,Goodridge L,Lévesque RC,Hasan NA,Dadlani M,Dixon B,Magierowski S,Masson L

更新日期：2020-04-17 00:00:00