Intra- versus intergroup variance in collective behavior.

abstract：:Ultraviolet (UV) reception is useful for such basic behaviors as mate choice, foraging, predator avoidance, communication, and navigation, whereas violet reception improves visual resolution and subtle contrast detection. UV and violet reception are mediated by the short wavelength-sensitive (SWS1) pigments that absor...

journal_title：Science advances

authors： Yokoyama S,Altun A,Jia H,Yang H,Koyama T,Faggionato D,Liu Y,Starmer WT

更新日期：2015-09-18 00:00:00

abstract：:Natively paired sequencing (NPS) of B cell receptors [variable heavy (VH) and light (VL)] and T cell receptors (TCRb and TCRa) is essential for the understanding of adaptive immunity in health and disease. Despite many recent technical advances, determining the VH:VL or TCRb:a repertoire with high accuracy and through...

journal_title：Science advances

authors： Tanno H,McDaniel JR,Stevens CA,Voss WN,Li J,Durrett R,Lee J,Gollihar J,Tanno Y,Delidakis G,Pothukuchy A,Ellefson JW,Goronzy JJ,Maynard JA,Ellington AD,Ippolito GC,Georgiou G

更新日期：2020-04-22 00:00:00

abstract：:Mimicking subcellular compartments containing enzymes in organisms is considered a promising approach to substitute for missing or lost cellular functions. Inspired by the multicompartment structures of cellular architectures, we present a novel multienzyme system based on hollow hydrogel microcapsules with flexible e...

journal_title：Science advances

authors： Wang H,Zhao Z,Liu Y,Shao C,Bian F,Zhao Y

更新日期：2018-06-15 00:00:00

abstract：:Spectroscopic methods with nanoscale lateral resolution are becoming essential in the fields of physics, chemistry, geology, biology, and materials science. However, the lateral resolution of laser-based mass spectrometry imaging (MSI) techniques has so far been limited to the microscale. This report presents the deve...

journal_title：Science advances

authors： Liang Z,Zhang S,Li X,Wang T,Huang Y,Hang W,Yang Z,Li J,Tian Z

更新日期：2017-12-08 00:00:00

abstract：:The mammalian retina system consists of a complicated photoreceptor structure, which exhibits extensive random synaptic connections. To study retinal development and degeneration, various experimental models have been used previously, but these models are often uncontrollable, are difficult to manipulate, and do not p...

journal_title：Science advances

authors： Ma Y,Han X,de Castro RB,Zhang P,Zhang K,Hu Z,Qin L

更新日期：2018-05-09 00:00:00

abstract：:About 40% of patients with non-small cell lung cancer (NSCLC) have stage IV cancer at the time of diagnosis. The only viable treatment options for metastatic disease are systemic chemotherapy and immunotherapy. Nonetheless, chemoresistance remains a major cause of chemotherapy failure. New immunotherapeutic modalities...

journal_title：Science advances

authors： Vinod N,Hwang D,Azam SH,Van Swearingen AED,Wayne E,Fussell SC,Sokolsky-Papkov M,Pecot CV,Kabanov AV

更新日期：2020-06-17 00:00:00

abstract：:Humans and animals have a "number sense," an innate capability to intuitively assess the number of visual items in a set, its numerosity. This capability implies that mechanisms to extract numerosity indwell the brain's visual system, which is primarily concerned with visual object recognition. Here, we show that netw...

journal_title：Science advances

authors： Nasr K,Viswanathan P,Nieder A

更新日期：2019-05-08 00:00:00

abstract：:The process of sheep and goat (caprine) domestication began by 9000 to 8000 BCE in Southwest Asia. The early Neolithic site at Aşıklı Höyük in central Turkey preserves early archaeological evidence of this transformation, such as culling by age and sex and use of enclosures inside the settlement. People's strategies f...

journal_title：Science advances

authors： Abell JT,Quade J,Duru G,Mentzer SM,Stiner MC,Uzdurum M,Özbaşaran M

更新日期：2019-04-17 00:00:00

abstract：:A semiconductor nanowire with strong spin-orbit coupling in proximity to a superconductor is predicted to display Majorana edge states emerging under a properly oriented magnetic field. The experimental investigation of these exotic states requires assessing the one-dimensional (1D) character of the nanowire and under...

journal_title：Science advances

authors： Estrada Saldaña JC,Žitko R,Cleuziou JP,Lee EJH,Zannier V,Ercolani D,Sorba L,Aguado R,De Franceschi S

更新日期：2019-07-05 00:00:00

abstract：:The key to the development of advanced materials is to understand their electronic structure-property relationship. Utilization of this understanding to design new electronic materials with desired properties led to modern epitaxial growth approaches for synthesizing artificial lattices, which for almost half a centur...

journal_title：Science advances

authors： Mascarenhas A,Fluegel B,Bhusal L

更新日期：2017-06-07 00:00:00

abstract：:Active materials are capable of converting free energy into directional motion, giving rise to notable dynamical phenomena. Developing a general understanding of their structure in relation to the underlying nonequilibrium physics would provide a route toward control of their dynamic behavior and pave the way for pote...

journal_title：Science advances

authors： Kumar N,Zhang R,de Pablo JJ,Gardel ML

更新日期：2018-10-12 00:00:00

abstract：:Human settlement of the Caribbean represents the only example in the Americas of peoples colonizing islands that were not visible from surrounding mainland areas or other islands. Unfortunately, many interpretive models have relied on radiocarbon determinations that do not meet standard criteria for reporting because ...

journal_title：Science advances

authors： Napolitano MF,DiNapoli RJ,Stone JH,Levin MJ,Jew NP,Lane BG,O'Connor JT,Fitzpatrick SM

更新日期：2019-12-18 00:00:00

abstract：:Dynamic modulation of soft helix in terms of the molecular organization, handedness, and pitch length could result in a sophisticated control over its functions, opening numerous possibilities toward the exploration of previously unidentified applications. Here, we report a dynamic and reversible transformation of a s...

journal_title：Science advances

authors： Yuan CL,Huang W,Zheng ZG,Liu B,Bisoyi HK,Li Y,Shen D,Lu Y,Li Q

更新日期：2019-10-04 00:00:00

abstract：:Biogenesis in prokaryotes and eukaryotes requires the insertion of α-helical proteins into cellular membranes for which they use universally conserved cellular machineries. In bacterial inner membranes, insertion is facilitated by YidC insertase and SecYEG translocon working individually or cooperatively. How insertas...

journal_title：Science advances

authors： Serdiuk T,Steudle A,Mari SA,Manioglu S,Kaback HR,Kuhn A,Müller DJ

更新日期：2019-01-30 00:00:00

abstract：:Coastal vertical land motion affects projections of sea-level rise, and subsidence exacerbates flooding hazards. Along the ~1350-km California coastline, records of high-resolution vertical land motion rates are scarce due to sparse instrumentation, and hazards to coastal communities are underestimated. Here, we consi...

journal_title：Science advances

authors： Blackwell E,Shirzaei M,Ojha C,Werth S

更新日期：2020-07-31 00:00:00

abstract：:Association of peripheral proteins with lipid bilayers regulates membrane signaling and dynamics. Pleckstrin homology (PH) domains bind to phosphatidylinositol phosphate (PIP) molecules in membranes. The effects of local PIP enrichment on the interaction of PH domains with membranes is unclear. Molecular dynamics simu...

journal_title：Science advances

authors： Yamamoto E,Domański J,Naughton FB,Best RB,Kalli AC,Stansfeld PJ,Sansom MSP

更新日期：2020-02-19 00:00:00

abstract：:Prosocial behavior is paradoxical because it often entails a cost to one's own welfare to benefit others. Theoretical models suggest that prosociality is driven by several forms of reciprocity. Although we know a great deal about how each of these forms operates in isolation, they are rarely isolated in the real world...

journal_title：Science advances

authors： Melamed D,Simpson B,Abernathy J

更新日期：2020-06-03 00:00:00

abstract：:The prenatal origins of heart disease in offspring have been established. However, research in species with developmental milestones comparable to humans is lacking, preventing translation of this knowledge to clinical contexts. Using sheep and chickens, two species with similar cardiovascular developmental milestones...

journal_title：Science advances

authors： Botting KJ,Skeffington KL,Niu Y,Allison BJ,Brain KL,Itani N,Beck C,Logan A,Murray AJ,Murphy MP,Giussani DA

更新日期：2020-08-19 00:00:00

abstract：:Regulatory T (Treg) cells are essential for peripheral tolerance and rely on the transcription factor (TF) Foxp3 for their generation and function. Several other TFs are critical for the Treg cell program. We found that mice deficient in Bcl11b TF solely in Treg cells developed fatal autoimmunity, and Bcl11b-deficient...

journal_title：Science advances

authors： Drashansky TT,Helm E,Huo Z,Curkovic N,Kumar P,Luo X,Parthasarathy U,Zuniga A,Cho JJ,Lorentsen KJ,Xu Z,Uddin M,Moshkani S,Zhou L,Avram D

更新日期：2019-08-07 00:00:00

abstract：:Quantitative three-dimensional (3D) computed tomography (CT) imaging of living single cells enables orientation-independent morphometric analysis of the intricacies of cellular physiology. Since its invention, x-ray CT has become indispensable in the clinic for diagnostic and prognostic purposes due to its quantitativ...

journal_title：Science advances

authors： Kelbauskas L,Shetty R,Cao B,Wang KC,Smith D,Wang H,Chao SH,Gangaraju S,Ashcroft B,Kritzer M,Glenn H,Johnson RH,Meldrum DR

更新日期：2017-12-06 00:00:00

abstract：:To gain insights into neutrophil heterogeneity dynamics in the context of sterile inflammation and wound healing, we performed a pseudotime analysis of single-cell flow cytometry data using the spanning-tree progression analysis of density-normalized events algorithm. This enables us to view neutrophil transitional su...

journal_title：Science advances

authors： Turner TC,Sok MCP,Hymel LA,Pittman FS,York WY,Mac QD,Vyshnya S,Lim HS,Kwong GA,Qiu P,Botchwey EA

更新日期：2020-10-30 00:00:00

abstract：:Wearable textile electronics are highly desirable for realizing personalized health management. However, most reported textile electronics can either periodically target a single physiological signal or miss the explicit details of the signals, leading to a partial health assessment. Furthermore, textiles with excelle...

journal_title：Science advances

authors： Fan W,He Q,Meng K,Tan X,Zhou Z,Zhang G,Yang J,Wang ZL

更新日期：2020-03-13 00:00:00

abstract：:A new set of time-of-day-dependent global maps of the lunar near-infrared water/hydroxyl (H2O/OH) absorption band strength near 2.8 to 3.0 μm constructed on the basis of Moon Mineralogy Mapper (M3) data is presented. The analyzed absorption band near 2.8 to 3.0 μm indicates the presence of surficial H2O/OH. To remove ...

journal_title：Science advances

authors： Wöhler C,Grumpe A,Berezhnoy AA,Shevchenko VV

更新日期：2017-09-08 00:00:00

abstract：:Inputs of nitrogen into terrestrial ecosystems, mainly via the use of ammonium-based fertilizers in agroecosystems, are enormous, but the fate of this nitrogen under elevated atmospheric carbon dioxide (CO2) is not well understood. We have taken advantage of a 15-year free-air CO2 enrichment study to investigate the i...

journal_title：Science advances

authors： Xu C,Zhang K,Zhu W,Xiao J,Zhu C,Zhang N,Yu F,Li S,Zhu C,Tu Q,Chen X,Zhu J,Hu S,Koide RT,Firestone MK,Cheng L

更新日期：2020-10-16 00:00:00

abstract：:E2F is a family of master transcription regulators involved in mediating diverse cell fates. Here, we show that residue-specific arginine methylation (meR) by PRMT5 enables E2F1 to regulate many genes at the level of alternative RNA splicing, rather than through its classical transcription-based mechanism. The p100/TS...

journal_title：Science advances

authors： Roworth AP,Carr SM,Liu G,Barczak W,Miller RL,Munro S,Kanapin A,Samsonova A,La Thangue NB

更新日期：2019-06-26 00:00:00

abstract：:Under rapid high-temperature, high-pressure loading, lattices exhibit complex elastic-inelastic responses. The dynamics of these responses are challenging to measure experimentally because of high sample density and extremely small relevant spatial and temporal scales. Here, we use an x-ray free-electron laser providi...

journal_title：Science advances

authors： Brown SB,Gleason AE,Galtier E,Higginbotham A,Arnold B,Fry A,Granados E,Hashim A,Schroer CG,Schropp A,Seiboth F,Tavella F,Xing Z,Mao W,Lee HJ,Nagler B

更新日期：2019-03-08 00:00:00

abstract：:Correlating spatial chemical information with the morphology of closely packed nanostructures remains a challenge for the scientific community. For example, supramolecular self-assembly, which provides a powerful and low-cost way to create nanoscale patterns and engineered nanostructures, is not easily interrogated in...

journal_title：Science advances

authors： Nowak D,Morrison W,Wickramasinghe HK,Jahng J,Potma E,Wan L,Ruiz R,Albrecht TR,Schmidt K,Frommer J,Sanders DP,Park S

更新日期：2016-03-25 00:00:00

abstract：:Continental rifting and seafloor spreading play a fundamental role in the generation of new crust. However, the distribution of magma and its relationship with tectonics and volcanism remain poorly understood, particularly in back-arc settings. We show evidence for a large, long-lived, off-axis magmatic intrusion loca...

journal_title：Science advances

authors： Hamling IJ,Hreinsdóttir S,Bannister S,Palmer N

更新日期：2016-06-03 00:00:00

abstract：:Posthemorrhagic hydrocephalus (PHH) in premature infants is a common neurological disorder treated with invasive neurosurgical interventions. Patients with PHH lack effective therapeutic interventions and suffer chronic comorbidities. Here, we report a murine lysophosphatidic acid (LPA)-induced postnatal PHH model tha...

journal_title：Science advances

authors： Lummis NC,Sánchez-Pavón P,Kennedy G,Frantz AJ,Kihara Y,Blaho VA,Chun J

更新日期：2019-10-09 00:00:00

abstract：:Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is an unexplained incapacitating illness that may affect up to 4 million people in the United States alone. There are no validated laboratory tests for diagnosis or management despite global efforts to find biomarkers of disease. We considered the possibility...

journal_title：Science advances

authors： Hornig M,Montoya JG,Klimas NG,Levine S,Felsenstein D,Bateman L,Peterson DL,Gottschalk CG,Schultz AF,Che X,Eddy ML,Komaroff AL,Lipkin WI

更新日期：2015-02-01 00:00:00