Long noncoding RNA DINO (damage induced noncoding) represses the development of gastric cancer by modulating p21 and Bcl-2 Associated X Protein (Bax) expression.

abstract：:Recently, glioma stem cells have been identified as the main cause of glioma propagation and recurrence and a number of several cell markers have been indicated as putative GSC markers. In the present work, a retrospective study to evaluate the prognostic potential of ability to generate GSCs in our series of 15 gliob...

journal_title：Journal of cellular biochemistry

authors： Miconi G,Palumbo P,Dehcordi SR,La Torre C,Lombardi F,Evtoski Z,Cimini AM,Galzio R,Cifone MG,Cinque B

更新日期：2015-05-01 00:00:00

abstract：:Small for gestational age (SGA) has a high risk of mortality and morbidity and is common in obstetrics. To date, no effective prediction and treatment tools are available. Acting as microRNA (miRNA) sponges and disease biomarkers are clear functions of circular RNAs (circRNAs). However, it is still unknown what role c...

journal_title：Journal of cellular biochemistry

authors： Wang Y,Li SF,Dang YJ,Shi XM,Chen L,Wang N,Cai Y,Zhao YY

更新日期：2020-01-01 00:00:00

abstract：:microRNAs (miRNAs) are noncoding RNAs that regulates the expression of target messenger RNAs (mRNAs). c-FLIP is an inhibitor of cell apoptosis through inhibition of caspase 8. miR-150, miR-504, and miR-519d were related to cancer cell proliferation, invasion, and migration in colorectal cancer (CRC). However, the role...

journal_title：Journal of cellular biochemistry

authors： Rong G,Yang X,Wu H,Wu Y

更新日期：2018-12-12 00:00:00

abstract：:Toxoplasma gondii an obligate intracellular parasite causes toxoplasmosis in homeothermic animals. Host invasion of this parasite is mediated by the formation of Moving Junction (MJ) complex which encompasses a network of microneme and Rhoptry Neck proteins (RONs) 2/4/5/8. Among these proteins, RON4 is the only cytoso...

journal_title：Journal of cellular biochemistry

authors： Vetrivel U,Nagarajan H,Thirumudi I

更新日期：2018-04-01 00:00:00

abstract：:Baicalein, a flavonoid present in the root of Scutellaria baicalensis, is well known for its antibacterial, antiviral, anti-inflammatory, antithrombotic, and antioxidant effects. Here we show that baicalein also attenuates cardiac hypertrophy. Aortic banding (AB) was performed to induce cardiac hypertrophy secondary t...

journal_title：Journal of cellular biochemistry

authors： Zong J,Zhang DP,Zhou H,Bian ZY,Deng W,Dai J,Yuan Y,Gan HW,Guo HP,Tang QZ

更新日期：2013-05-01 00:00:00

abstract：:We observed that treatment of prostate cancer cells for 24 h with magnolol, a phenolic component extracted from the root and stem bark of the oriental herb Magnolia officinalis, induced apoptotic cell death in a dose- and time-dependent manner. A sustained inhibition of the major survival signal, Akt, occurred in magn...

journal_title：Journal of cellular biochemistry

authors： Lee DH,Szczepanski MJ,Lee YJ

更新日期：2009-04-15 00:00:00

abstract：:We have examined the effect of polyoma virus infection of primary mouse embryo cells on the tyrosyl kinase activity associated with the cellular src gene product, pp60c-src. The results of our studies demonstrate that infection of mouse cells with wild-type polyoma virus or viral mutants capable of transforming rodent...

journal_title：Journal of cellular biochemistry

authors： Bolen JB,Lewis AM Jr,Israel MA

更新日期：1985-01-01 00:00:00

abstract：:As an important tumor suppressor, programmed cell death 4 (PDCD4) influences transcription and translation of multiple genes, and modulates different signal transduction pathways. However, the upstream regulation of this gene is largely unknown. In this study, we found that microRNA-182 (miRNA-182, miR-182) was upregu...

journal_title：Journal of cellular biochemistry

authors： Wang YQ,Guo RD,Guo RM,Sheng W,Yin LR

更新日期：2013-07-01 00:00:00

abstract：:Osteopontin is a secreted glycoprotein with adhesive and migratory functions. Cellular interactions with osteopontin are mediated through integrin receptors which recognize the RGD domain. Recently, CD44, a non-integrin, multifunctional adhesion molecule was identified as an osteopontin receptor. CD44 is a ubiquitous ...

journal_title：Journal of cellular biochemistry

authors： Smith LL,Greenfield BW,Aruffo A,Giachelli CM

更新日期：1999-04-01 00:00:00

abstract：:Tetralogy of Fallot (TOF) is the most common form of cyanotic congenital heart disease. To identify endogenous peptides possibly involved in the progression of TOF, we performed comparative peptidomic profiling of maternal serum between normal fetuses and fetuses suffering from TOF. A total of 278 differentially expre...

journal_title：Journal of cellular biochemistry

authors： Zhuang B,Hu Y,Fan X,Li M,Zhu J,Liu H,Cao L,Liang D,Zhang J,Yu Z,Han S

更新日期：2018-01-01 00:00:00

abstract：:Accumulating studies indicates that circular RNAs (circRNAs) play an imperative role in modulating cancer progression and metastasis. In the previous study, elevated circ_0029426 was first observed in glioblastoma (GBM) tissues compared with normal tissues by circRNA microarray. Our aim is to study the function and me...

journal_title：Journal of cellular biochemistry

authors： Zhang G,Sun W,Zhu L,Feng Y,Wu L,Li T

更新日期：2019-06-01 00:00:00

abstract：:The conversion of expandable liver progenitor cells into pancreatic beta cells would provide a renewable cell source for diabetes cell therapy. Previously, we reported the establishment of liver epithelial progenitor cells (LEPCs). In this work, LEPCs were modified into EGFP/Pdx-1 LEPCs, cells with stable expression o...

journal_title：Journal of cellular biochemistry

authors： Jin CX,Li WL,Xu F,Geng ZH,He ZY,Su J,Tao XR,Ding XY,Wang X,Hu YP

更新日期：2008-05-01 00:00:00

abstract：:Laryngocarcinoma is the most common head and neck cancer and has a high incidence and mortality, causing about 83 000 deaths per year worldwide. Our research aimed to investigate the possible role of long noncoding RNA (lncRNA) taurine upregulated gene 1 (TUG1) in laryngocarcinoma development. The messenger RNA (mRNA)...

journal_title：Journal of cellular biochemistry

authors： Zhuang S,Liu F,Wu P

更新日期：2019-08-01 00:00:00

abstract：:Colorectal cancer is the third most common cancer with a 5-year survival rate of less than 10%. It is caused by alterations of multiple signal pathways which are affected by both genetic and environmental factors. In some cases, EGFR is important in the carcinogenesis of colorectal cancer suggesting anti-EGFR therapy ...

journal_title：Journal of cellular biochemistry

authors： Chen J,Huang XF,Katsifis A

更新日期：2010-12-01 00:00:00

abstract：:The tetrazolium salt 3(4,5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT) is reduced to formazan by the succinate dehydrogenase system of active mitochondria, and hence, specifically used to assay for the viable cells, such as measurement of cell proliferation, cytotoxicity, and cell number. However, in ...

journal_title：Journal of cellular biochemistry

authors： Chakrabarti R,Kundu S,Kumar S,Chakrabarti R

更新日期：2000-09-18 00:00:00

abstract：:Forkhead box class O6 (FOXO6) is an important member of FOXO family, which has been demonstrated to be implicated in tumor development. However, the role of FOXO6 in colorectal cancer (CRC) is still unclear. The study aimed to investigate the potential roles of FOXO6 in the development of CRC. Our results showed that ...

journal_title：Journal of cellular biochemistry

authors： Li Q,Tang H,Hu F,Qin C

更新日期：2019-03-01 00:00:00

abstract：:This study aimed at elucidating the molecular mechanism of miR-381-3p in cervical cancer progression, which may provide a novel therapeutic target for patients with cervical cancer. The expression of miR-381-3p was confirmed by quantitative reverse transcription polymerase chain reaction. Microarray analysis was condu...

journal_title：Journal of cellular biochemistry

authors： Shang A,Zhou C,Bian G,Chen W,Lu W,Wang W,Li D

更新日期：2019-01-01 00:00:00

abstract：:Myelin basic protein (MBP) is a major component of the myelin sheath whose production is developmentally controlled during myelinogenesis. Earlier studies have indicated that programmed expression of the MBP gene is regulated at the level of transcription. Evidently, the MB1 regulatory motif located between nucleotide...

journal_title：Journal of cellular biochemistry

authors： Muralidharan V,Tretiakova A,Steplewski A,Haas S,Amini S,Johnson E,Khalili K

更新日期：1997-09-15 00:00:00

abstract：:Bone formation in the embryo, and during adult fracture repair and remodeling, involves the progeny of a small number of cells called mesenchymal stem cells (MSCs). These cells continuously replicate themselves, while a portion become committed to mesenchymal cell lineages such as bone, cartilage, tendon, ligament, an...

journal_title：Journal of cellular biochemistry

authors： Bruder SP,Fink DJ,Caplan AI

更新日期：1994-11-01 00:00:00

abstract：:Obesity and aging lead to abnormal transforming growth factor-β1 (TGF-β1) signaling in the hypothalamus, triggering the imbalance on glucose metabolism and energy homeostasis. Here, we determine the effect of acute exercise on TGF-β1 expression in the hypothalamus of two models of obesity in mice. The bioinformatics a...

journal_title：Journal of cellular biochemistry

authors： Silva VRR,Lenhare L,Katashima CK,Morari J,M-Assis A,Gaspar RS,da Silva ASR,Moura LP,Pauli JR,Cintra DE,Velloso LA,Ropelle ER

更新日期：2019-10-01 00:00:00

abstract：:The identification and purification of murine multipotent mesenchymal stem cells (MSCs) have been difficult due to their low frequency, the presence of contaminating cell types and lack of unambiguous markers. Using a magnetic micro-beads negative selection technique to remove hematopoietic cells from mouse bone marro...

journal_title：Journal of cellular biochemistry

authors： McKenzie KP,Mayer DC,Aubin JE

更新日期：2013-05-01 00:00:00

abstract：:Diacylglycerol kinases (DGKs) attenuate diacylglycerol signaling by converting this lipid to phosphatidic acid (PA). The nine mammalian DGKs that have been identified are widely expressed, but each isoform has a unique tissue and subcellular distribution. Their kinase activity is regulated by mechanisms that modify th...

journal_title：Journal of cellular biochemistry

authors： Topham MK

更新日期：2006-02-15 00:00:00

abstract：:HSP90 chaperones are transducer proteins of many signaling pathways in cells. Using a highly specific inhibitor, geldanamycin (GA), an increasing number of the HSP90 client proteins have been identified. Nevertheless, there is little information on the differential transactivation of the two isoforms of the hsp90 gene...

journal_title：Journal of cellular biochemistry

authors： Chao CC,Sun FC,Wang CH,Lo CW,Chang YS,Chang KC,Chang MD,Lai YK

更新日期：2008-07-01 00:00:00

abstract：:Bladder cancer is the most common malignancy with high recurrence. Currently, the long noncoding RNAs (lncRNAs) have been suggested to play vital roles in the pathogenesis of bladder cancer. The present study investigated the role of lncRNA MIR503 host gene (MIR503HG) in the pathogenesis of bladder cancer by using bot...

journal_title：Journal of cellular biochemistry

authors： Qiu F,Zhang MR,Zhou Z,Pu JX,Zhao XJ

更新日期：2019-06-01 00:00:00

abstract：:Interleukin-1β (IL-1β) assumes a centric role in the regulation of immune and inflammatory responses and thus has been recognized in immune mediated diseases like type 2 diabetes mellitus (T2DM). We aimed to investigate expressed level of IL-1β and its relation with IL-1β -511T>C polymorphism in T2DM patients. This st...

journal_title：Journal of cellular biochemistry

authors： Tayel SI,Fouda EAM,Elshayeb EI,Eldakamawy ARA,El-Kousy SM

更新日期：2018-07-01 00:00:00

abstract：:Metallo Beta (β) Lactamases (MBL) are metal dependent bacterial enzymes that hydrolyze the β-lactam antibiotics. In recent years, MBL have received considerable attention because it inactivates most of the β-lactam antibiotics. Increase in dissemination of MBL encoding antibiotic resistance genes in pathogenic bacteri...

journal_title：Journal of cellular biochemistry

authors： Parimelzaghan A,Anbarasu A,Ramaiah S

更新日期：2016-06-01 00:00:00

abstract：:Excitatory amino acids (EAAs) are found present in the nervous and reproductive systems of animals. Numerous studies have demonstrated a regulatory role for Glutamate (Glu), d-aspartate ( d-Asp) and N-methyl- d-aspartate (NMDA) in the control of spermatogenesis. EAAs are able to stimulate the Glutamate receptors, incl...

journal_title：Journal of cellular biochemistry

authors： Santillo A,Falvo S,Di Fiore MM,Di Giacomo Russo F,Chieffi P,Usiello A,Pinelli C,Baccari GC

更新日期：2019-02-14 00:00:00

abstract：:SMAD ubiquitination regulatory factor 1 (SMURF1) has been described as a tumor suppressor in multiple aggressive cancers. Nevertheless, the potential role of SMURF1 in ovarian cancer invasion and epithelial-to-mesenchymal transition (EMT) remains unclear. The aim of this study was to evaluate the efficacy of SMURF1 on...

journal_title：Journal of cellular biochemistry

authors： Fan X,Wang Y,Fan J,Chen R

更新日期：2019-06-01 00:00:00

abstract：:Resident T lymphocytes have been found to exert helper and suppressor regulatory influences with regard to polyclonal activation of murine splenic B lymphocytes elicited by lipopolysaccharide. In the normal adult spleen, only T cell helper influences are exercised over polyclonal B cell activation. This activity is a ...

journal_title：Journal of cellular biochemistry

authors： Goodman MG,Weigle WO

更新日期：1982-01-01 00:00:00

abstract：:Amplification of MYCN is one of the most important prognostic markers for neuroblastoma and is correlated with rapid tumor progression and poor prognosis. MYCN belongs to the Myc/Max/Mad/Mnt network of proteins that regulate proliferation, apoptosis, and differentiation. It is well established that MYCN is downregulat...

journal_title：Journal of cellular biochemistry

authors： Smith AG,Popov N,Imreh M,Axelson H,Henriksson M

更新日期：2004-08-15 00:00:00