Enhanced production of triacylglycerols and polyunsaturated fatty acids in novel acid-tolerant mutants of the green microalga Chlorella saccharophila.

abstract：:Several carbon sources were investigated for the production of 1,3-propanediol (PDO) and 2,3-butanediol (BDO) simultaneously, using an isolated indigenous Klebsiella sp. Ana-WS5. The results indicate that glycerol is a suitable carbon source for both BDO and PDO production. Further investigation suggests that adjustme...

journal_title：Bioprocess and biosystems engineering

authors： Yen HW,Li FT,Wong CL,Chang JS

更新日期：2014-03-01 00:00:00

abstract：:In this study, the modulation of enzymatic biocatalysts were developed by the use of lipase B from Candida antarctica covalently immobilized on an eco-friendly support, cashew apple bagasse, activated with 10% glycidol-ethylenediamine-glutaraldehyde (GEG) under different immobilization strategies (5 mM or 100 mM ionic...

journal_title：Bioprocess and biosystems engineering

authors： de Souza TC,de Sousa Fonseca T,de Sousa Silva J,Lima PJM,Neto CACG,Monteiro RRC,Rocha MVP,de Mattos MC,Dos Santos JCS,Gonçalves LRB

更新日期：2020-12-01 00:00:00

abstract：:The yeast Rhodotorula glutinis was examined for its ability to remove Pb(2+) from aqueous solution. Within 10 min of contact, Pb(2+) sorption reached nearly 80% of the total Pb(2+) sorption. The optimum initial pH value for removal of Pb(2+ )was 4.5-5.0. The percentage sorption increased steeply with the biomass conce...

journal_title：Bioprocess and biosystems engineering

authors： Cho DH,Kim EY

更新日期：2003-03-01 00:00:00

abstract：:Cucurbitacin B (CuB) and its glycoside, cucurbitacin B 2-o-β-D-glucoside (CuBg), abundantly occur in the pedicels of Cucumis melo. Compared with CuB, CuBg is not efficiently extracted from the pedicels. Furthermore, the anticancer activity of CuBg is lower than that of the aglycone. A process for CuBg biotransformatio...

journal_title：Bioprocess and biosystems engineering

authors： Mei J,Li S,Jin H,Tang L,Yi Y,Wang H,Ying G

更新日期：2016-09-01 00:00:00

abstract：:During ribonucleic acid fermentation, the fermentative processes were researched at pH controlled at 4.0 and under natural conditions. Unstructured models in a 50-L airlift fermentor were established for batch RNA production at pH 4.0 using the Verhulst equation for microbial growth, the Luedeking-Piret equation for p...

journal_title：Bioprocess and biosystems engineering

authors： Li B,Chen X,Ren H,Li L,Xiong J,Bai J,Chen Y,Wu J,Ying H

更新日期：2012-03-01 00:00:00

abstract：:Menaquinone-7 (MK-7), a subtype of vitamin K, has received a significant attention due to its effect on improving bone and cardiovascular health. Current fermentation strategies, which involve static fermentation without aeration or agitation, are associated with low productivity and scale-up issues and hardly justify...

journal_title：Bioprocess and biosystems engineering

authors： Mahdinia E,Demirci A,Berenjian A

更新日期：2017-10-01 00:00:00

abstract：:Mate (Ilex paraguariensis) is an important natural product in the economic and cultural context of Brazil. Peroxidase and polyphenol oxidase have been responsible for quality deterioration and browning in mate. The objective of this work was to investigate a methodology of extraction and enzymatic activity determinati...

journal_title：Bioprocess and biosystems engineering

authors： Ceni GC,Baldissera EM,Antunes OA,Vladimir Oliveira J,Dariva C,de Oliveira D

更新日期：2008-10-01 00:00:00

abstract：:The major nutrients, pH and temperature were evaluated for the exopolysaccharide (EPS) production by Daedalea dickinsii in submerged culture to derive an optimal medium composition and conditions as follows: 50 g/L maltose, 5 g/L soy peptone, 5 mM CaCl(2), at pH 6.0 and 28 °C. A purified EPS fraction was attained from...

journal_title：Bioprocess and biosystems engineering

authors： Mao DB,Shi CW,Wu JY,Xu CP

更新日期：2014-07-01 00:00:00

abstract：:Calcitriol is an important drug used for treating osteoporosis, which can be produced from vitamin D3. The current method of producing calcitriol from vitamin D3 during cultivation of microbial cells results in low yields of calcitriol and high purification costs. Therefore, in this study, the steps of cell cultivatio...

journal_title：Bioprocess and biosystems engineering

authors： Kang DJ,Im JH,Kang JH,Kim KH

更新日期：2015-07-01 00:00:00

abstract：:Gas sparging performances of a flat sheet and tubular polymeric membranes were investigated in 3.1 m bubble column bioreactor operated in a semi batch mode. Air-water and air-CMC (Carboxymethyl cellulose) solutions of 0.5, 0.75 and 1.0 % w/w were used as interacting gas-liquid mediums. CMC solutions were employed in t...

journal_title：Bioprocess and biosystems engineering

authors： Tirunehe G,Norddahl B

更新日期：2016-04-01 00:00:00

abstract：:The design and development of the neural network (NN)-based controller performance for the activated sludge process in sequencing batch reactor (SBR) is presented in this paper. Here we give a comparative study of various neural network (NN)-based controllers such as the direct inverse control, internal model control ...

journal_title：Bioprocess and biosystems engineering

authors： Azwar,Hussain MA,Ramachandran KB

更新日期：2006-03-01 00:00:00

abstract：:High amounts of outer membrane (OM) components were released in glucose-limited fed-batch (GLFB) cultures at 37 degrees C at specific growth rates approaching 0.05 h(-1). Endotoxin analyses from a 20 degrees C GLFB culture gave similar results. An alternative fermentation technique, the temperature-limited fed-batch (...

journal_title：Bioprocess and biosystems engineering

authors： Svensson M,Han L,Silfversparre G,Häggström L,Enfors SO

更新日期：2005-04-01 00:00:00

abstract：:A new protein assay system for the antigen-antibody interaction was developed by immobilization of carcinoembryonic antibody (anti-CEA) onto magnetic-core/gold-shell nanoparticles-functionalized biomimetic interface on multiporous polythionine modified magnetic carbon paste electrodes (MCPE). Differential pulse voltam...

journal_title：Bioprocess and biosystems engineering

authors： Tang D,Yuan R,Chai Y

更新日期：2008-02-01 00:00:00

abstract：:Escherichia coli AFP111, a pflB, ldhA, ptsG triple mutant of E. coli W1485, can be recovered for additional succinate production in fresh medium after two-stage fermentation (an aerobic growth stage followed by an anaerobic production stage). However, the specific productivity is lower than that of two-stage fermentat...

journal_title：Bioprocess and biosystems engineering

authors： Ma JF,Jiang M,Chen KQ,Xu B,Liu SW,Wei P,Ying HJ,Chang HN,Ouyang PK

更新日期：2011-05-01 00:00:00

abstract：:Bacterial cellulose (BC) exhibits unique properties such as high purity compared to plant-based cellulose; however, commercial production of BC has remained a challenge, primarily due to the strain properties of cellulose-producing bacteria. Herein, we developed a functional and stable BC production system in genetica...

journal_title：Bioprocess and biosystems engineering

authors： Buldum G,Bismarck A,Mantalaris A

更新日期：2018-02-01 00:00:00

abstract：:The performance of down-flow hanging sponge (DHS) system treating UASB reactor effluent at different sponge volume of 38.2, 28.7, 19.1 and 9.6% was investigated. The hydraulic retention time (HRT) and flow rate were kept constant at 2.6 h and 0.46 m(3)/day, respectively. The results obtained indicated that reducing th...

journal_title：Bioprocess and biosystems engineering

authors： Tawfik A,Ohashi A,Harada H

更新日期：2010-09-01 00:00:00

abstract：:Of various metal ions (Ca2+, Cr3+, Cu2+, Fe2+, Mg2+, Mn2+, Ni2+ and Zn2+) added to the culture medium of Agrobacterium tumefaciens at 1 mM, only Ca2+ increased Coenzyme Q10 (CoQ(10)) content in cells without the inhibition of cell growth. In a pH-stat fed-batch culture, supplementation with 40 mM of CaCO3 increased th...

journal_title：Bioprocess and biosystems engineering

authors： Ha SJ,Kim SY,Seo JH,Jeya M,Zhang YW,Ramu T,Kim IW,Lee JK

更新日期：2009-08-01 00:00:00

abstract：:The bacteriostatic properties of carbon disulphide (CS₂) hamper its biodegradation in conventional biofilters. The response of four biofilters operating in downflow mode and reverse-flow mode was compared in a laboratory-scale plant treating CS₂ under sudden short-term changes in operating conditions. A process shutdo...

journal_title：Bioprocess and biosystems engineering

authors： Rojo N,Gallastegui G,Gurtubay L,Barona A,Elías A

更新日期：2013-04-01 00:00:00

abstract：:The present study aimed to determine the degradation and transformation of three-ring PAHs phenanthrene and anthracene by Cryptococcus sp. MR22 and Halomonas sp. BR04 under halophilic conditions. The growth progress of Cryptococcus sp. MR22 and Halomonas sp. BR04 on anthracene and phenanthrene was monitored by colony-...

journal_title：Bioprocess and biosystems engineering

authors： Al Farraj DA,Hadibarata T,Yuniarto A,Alkufeidy RM,Alshammari MK,Syafiuddin A

更新日期：2020-12-01 00:00:00

abstract：:Chemical absorption-biological reduction (BioDeNOx), which uses Fe(II)(EDTA) as a complexing agent for promoting the mass transfer efficiency of NO from gas to water, is a promising technology for removing nitric oxide (NO) from flue gases. The carbon source and pH are important parameters for Fe(II)(EDTA)-NO (the pro...

journal_title：Bioprocess and biosystems engineering

authors： Chen J,Wang L,Zheng J,Chen J

更新日期：2015-07-01 00:00:00

abstract：:Biological synthesis of succinic acid at low pH values was favored since it not only decreased investment cost but also simplified downstream purification process. In this study, the feasibility of using glutamate decarboxylase system to improve succinic acid production of Escherichia coli AFP111, a succinate-producin...

journal_title：Bioprocess and biosystems engineering

authors： Wu M,Li X,Guo S,Lemma WD,Zhang W,Ma J,Jia H,Wu H,Jiang M,Ouyang P

更新日期：2017-04-01 00:00:00

abstract：:A whole-cell biocatalytic process for uridine 5'-monophosphate (UMP) production from orotic acid by Saccharomyces cerevisiae was developed. To rationally redistribute the metabolic flux between glycolysis and pentose phosphate pathway, statistical methods were employed first to find out the critical factors in the pro...

journal_title：Bioprocess and biosystems engineering

authors： Liu D,Chen Y,Li A,Xie J,Xiong J,Bai J,Chen X,Niu H,Zhou T,Ying H

更新日期：2012-06-01 00:00:00

abstract：:(R)-2-hydroxy-4-phenylbutyric acid (R-HPBA) is a valuable intermediate for the synthesis of angiotensin-converting enzyme inhibitors. The asymmetric reduction of 2-oxo-4-phenylbutyric acid (OPBA) by oxidoreductases is an efficient approach for its synthesis. Here, we report a novel biocatalytic approach for asymmetric...

journal_title：Bioprocess and biosystems engineering

authors： Wang X,Yu Z,Tang J,Yi D,Chen S

更新日期：2018-09-01 00:00:00

abstract：:Gamma-aminobutyric acid (GABA) production by free and Ca-alginate encapsulated cells of Enterococcus faecium CFR 3003 was investigated. Mass transfer rates characterizing the GABA production process using encapsulated cells were investigated. Experiments were performed to investigate external film and internal pore di...

journal_title：Bioprocess and biosystems engineering

authors： Divyashri G,Prapulla SG

更新日期：2015-03-01 00:00:00

abstract：:Lactococcus lactis spp. lactis and Lactococcus lactis spp. cremoris are widely used in the manufacture of fermented milk. These strains were compared for production of Dipeptidyl Peptidase IV (DPP IV) enzyme in terms of enzyme activity, specific growth rates and productivity. Lactococcus lactis spp. lactis was produce...

journal_title：Bioprocess and biosystems engineering

authors： Ustün O,Ongen G

更新日期：2012-10-01 00:00:00

abstract：:The paper describes a recombinant Schneider 2 (rS2) cell culture and protein expression in a bioreactor. S2 cells were transfected with a plasmid containing a fusion protein (human mu opioid receptor, hMOR, and green fluorescent protein, EGFP) under the control of inducible metallothionein promoter. A bioprocess in a ...

journal_title：Bioprocess and biosystems engineering

authors： Brillet K,da Conceição MM,Pattus F,Pereira CA

更新日期：2006-04-01 00:00:00

abstract：:ε-Poly-L-lysine (ε-PL), one of the only two homo-poly amino acids known in nature, is used as a preservative. In this study, strategies of feeding precursor L-lysine into 5 L laboratory scale fermenters, including optimization of L-lysine concentration and time, was investigated to optimize the production of ε-PL by S...

journal_title：Bioprocess and biosystems engineering

authors： Chen XS,Ren XD,Zeng X,Zhao FL,Tang L,Zhang HJ,Zhang JH,Mao ZG

更新日期：2013-12-01 00:00:00

abstract：:This study assessed the simultaneous nitrification and denitrification processes and remaining organic matter removal from anaerobic reactor effluent treating wastewater in a single reactor. A structured-bed reactor, with polyurethane foam as support media, was subjected to intermittent aeration and effluent recircula...

journal_title：Bioprocess and biosystems engineering

authors： Silva BG,Damianovic MHRZ,Foresti E

更新日期：2018-08-01 00:00:00

abstract：:The influence of sugars in culture media on the kinetics of the mono- and disaccharide uptake and cell growth behavior was studied by mid-infrared spectroscopy using a Fourier transform infrared spectrometer (FT-IR) equipped with an attenuate total reflection accessory (ATR). We performed the plant cell cultivation wi...

journal_title：Bioprocess and biosystems engineering

authors： Yamanaka A,Hashimoto A,Matsuo T,Kanou M,Suehara K,Kameoka T

更新日期：2007-11-01 00:00:00

abstract：:In this study, hydrolysis of marine algal biomass Kappaphhycus alvarezii using two different acid catalysts was examined with the goal of identifying optimal reaction conditions for the formation of sugars and by-products. K. alvarezii were hydrolyzed by autoclave using sulfuric acid or hydrochloric acid as catalyst w...

journal_title：Bioprocess and biosystems engineering

authors： Meinita MD,Hong YK,Jeong GT

更新日期：2012-01-01 00:00:00