Craniocervical Rosai-Dorfman Disease Involving the Vertebral Artery: Case Report and Literature Review.

Abstract:

BACKGROUND:Rosai-Dorfman disease (RDD), also known as sinus histiocytosis with massive lymphadenopathy, is a rare non-Langerhans cell reactive histiocytic disorder that rarely occurs in the central nervous system (CNS). Extranodal RDD most frequently involves the skin, upper respiratory tract, soft tissue, gastrointestinal tracts, bones, breast, and CNS. CASE DESCRIPTION:RDD of the CNS infiltrates most commonly the dura of the sella, cavernous sinus, and the periclival regions. It is usually clinically and radiologically mistaken for meningioma because of its focal dural-based aspect. RDD is confirmed histologically by lymphoplasmacytic cells and histiocytes of varying size showing emperipolesis (lymphocytophagocytosis). To date, only 4 cases of RDD displaying spinal cord compression secondary to craniocervical junction involvement have been reported. CONCLUSION:We report the case of a patient diagnosed with RDD localized at the foramen magnum extending to the base of the odontoid process and involving the V4 segment vertebral artery.

journal_name

World Neurosurg

journal_title

World neurosurgery

authors

Baassiri W,Moussalem CK,Massaad E,Zeidan YH,Darwish H

doi

10.1016/j.wneu.2019.09.072

subject

Has Abstract

pub_date

2020-01-01 00:00:00

pages

69-73

eissn

1878-8750

issn

1878-8769

pii

S1878-8750(19)32502-1

journal_volume

133

pub_type

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