Abstract：
BACKGROUND:None of the existing prognostic scoring systems for spinal epidural abscess (SEA) include albumin despite albumin's established role in inflammation, nutrition, lipid peroxidation, and regulation of apoptosis. The purpose of the present study was to determine the prognostic value of albumin in SEA. METHODS:We performed a retrospective, case-control study of 2 independent data sets: patients with SEA in an institutional population and patients in the National Surgical Quality Improvement Program (NSQIP). Bivariate analyses and multivariate analyses were used to determine whether albumin is an independent prognostic factor for survival in both data sets. RESULTS:For the 1053 patients with SEA in the institutional cohort, the 90-day postdischarge mortality was 134 (12.7%). Overall, 633 (60.1%) underwent surgery in the initial admission, with a 30-day postoperative mortality rate of 5.5% (n = 35). For the 1154 patients with SEA in the NSQIP database, the 30-day postoperative mortality rate was 3.6% (n = 42). The rate of 90-day postdischarge mortality in the institutional cohort for patients with albumin <2.3 g/dL was 25.1%. In contrast, the rate for patients with albumin >3.3 g/dL was 4.5%. On multivariate analysis of the NSQIP database, hypoalbuminemia was an independent prognostic factor for 30-day postoperative mortality. On multivariate analysis of the institutional cohort, hypoalbuminemia remained a prognostic factor for 90-day postdischarge mortality. CONCLUSION:Albumin was validated as an independent prognostic factor in patients with SEA. The lack of this marker in existing scoring systems underscores the need for updated models to optimize risk stratification and shared decision-making before surgery.
journal_name
World Neurosurgjournal_title
World neurosurgeryauthors
Karhade AV,Shah AA,Lin KY,Ogink PT,Shah KC,Nelson SB,Schwab JHdoi
10.1016/j.wneu.2018.11.182subject
Has Abstractpub_date
2019-03-01 00:00:00pages
e416-e426eissn
1878-8750issn
1878-8769pii
S1878-8750(18)32741-4journal_volume
123pub_type
杂志文章,多中心研究abstract：BACKGROUND:Cone beam computed tomography (CBCT) imaging is used commonly in neurointerventional surgery for rapid intraprocedural assessment and planning of intracranial interventions. Our goal was to evaluate the ability of immediate postprocedural CBCT scan in assessing potential complications in pediatric patients. ...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.12.003
更新日期：2020-03-01 00:00:00
abstract：BACKGROUND:Transforaminal lumbar interbody fusion (TLIF) is an effective treatment of upper lumbar intervertebral disk herniation. However, its clinical efficacy for adjacent segment disk degeneration (ASDD) remains undefined. Therefore, the biomechanical evaluation of ASDD caused by TLIF after pedicle screw fixation (...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.11.195
更新日期：2018-11-29 00:00:00
abstract：BACKGROUND:Endodermal cysts of the oculomotor nerve are rare presentations. Only case reports are available to help guide clinicians with managing this rare entity. CASE DESCRIPTION:A 3-year-old boy presented with an acute on chronic left oculomotor nerve palsy due to a left interpeduncular cistern cyst found on magne...
journal_title：World neurosurgery
pub_type：
doi：10.1016/j.wneu.2020.05.038
更新日期：2020-08-01 00:00:00
abstract：BACKGROUND:Quantitative magnetic resonance angiography (qMRA) using noninvasive optimal vessel analysis (NOVA) is a novel noninvasive imaging technique that is being increasingly used to measure blood flow in extracranial and intracranial arteries. By providing important quantitative flow data, NOVA qMRA can facilitate...
journal_title：World neurosurgery
pub_type：
doi：10.1016/j.wneu.2019.10.088
更新日期：2020-03-01 00:00:00
abstract：BACKGROUND:The number of patients treated with novel oral anticoagulants (NOACs) is increasing. Despite growing clinical relevance, guidelines on the perioperative management of neurosurgical patients treated with NOACs are still lacking. The aim of this study was to analyze the occurrence of postoperative bleeding eve...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2017.06.105
更新日期：2017-09-01 00:00:00
abstract：OBJECTIVE:To determine the stability of fusion constructs with unilateral pedicle screw (UPS) or bilateral pedicle screw (BPS) fixation with and without an interbody implant using the lateral lumbar interbody (LLIF) approach. METHODS:Standard nondestructive flexibility tests were performed on 13 cadaveric lumbar speci...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.02.053
更新日期：2018-05-01 00:00:00
abstract：OBJECTIVE:To evaluate the parameters related to the high risk of preoperative seizures in infants (1 year or younger) with ruptured intracranial aneurysms. METHODS:Infants with ruptured intracranial aneurysms treated at our institution from January 2012 to January 2018 were retrospectively analyzed. Seventeen similar ...
journal_title：World neurosurgery
pub_type： 杂志文章,评审
doi：10.1016/j.wneu.2018.07.049
更新日期：2018-10-01 00:00:00
abstract：OBJECTIVE:The aim of this systematic literature review is to evaluate recent attempts in creating a standardized multidisciplinary approach combining tumor treatment with current vertebral stabilization techniques for palliative treatment of vertebral metastasis in patients who do not fall into the NOMS (neurologic, on...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.05.042
更新日期：2019-08-01 00:00:00
abstract：OBJECTIVE:Malformations in the craniocervical junction (CCJ) are rare in the pediatric population but often need surgical treatment. We present a pediatric case series of patients treated with a 2-stage surgical approach with a halo vest and occipitocervical fusion and review complications and outcomes. METHODS:A retr...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2020.11.079
更新日期：2020-11-20 00:00:00
abstract：BACKGROUND:Spindle cell oncocytomas are extremely rare neoplasms of the sellar, parasellar, and suprasellar regions that can frequently mimic pituitary adenomas. Fewer than 50 cases have been ever reported in the literature, and there is no consensus on best treatments to be provided. CASE DESCRIPTION:We hereby presen...
journal_title：World neurosurgery
pub_type： 杂志文章,评审
doi：10.1016/j.wneu.2020.05.255
更新日期：2020-10-01 00:00:00
abstract：BACKGROUND:Scalp arteriovenous malformation is a rare disease. In terms of treatment, surgical removal is often effective and performed. With the development of endovascular treatments, a combination of surgical removal and embolization is now often performed. CASE DESCRIPTION:A 44-year-old man presented with a mass i...
journal_title：World neurosurgery
pub_type：
doi：10.1016/j.wneu.2020.02.138
更新日期：2020-06-01 00:00:00
abstract：BACKGROUND:The development of endovascular techniques has offered extraordinary therapeutic opportunities to treat intracranial aneurysms. However, mainly for anterior circulation aneurysms, no clear superiority of these techniques compared with microsurgical clipping has been shown in terms of morbidity, mortality, an...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.06.150
更新日期：2019-10-01 00:00:00
abstract：BACKGROUND:An awake throughout (AT) approach for awake craniotomy is mostly under utilized. The purpose of this study was to review the efficacy of the technique at our tertiary care center. The primary objective was to identify the incidence of perioperative complications. The secondary objective was to review the pat...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.03.127
更新日期：2019-06-01 00:00:00
abstract：OBJECTIVE:To discuss lessons learned from an initial lateral lumbar interbody fusion (LLIF) experience with a focus on evolving surgical technique, complication avoidance, and new motor and sensory outcomes after implementation of a modified surgical approach. METHODS:A retrospective analysis of a prospectively collec...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.09.180
更新日期：2019-01-01 00:00:00
abstract：BACKGROUND:Ankylosing spondylitis (AS) is an inflammatory disease that involves above all the spine and the pelvis. In the spine, the inflammatory processes cause the formation of syndesmophytes between the vertebral bodies and the ossification of ligaments, with bony overgrowth. In this setting, dysphagia is a rare bu...
journal_title：World neurosurgery
pub_type： 杂志文章,评审
doi：10.1016/j.wneu.2020.04.031
更新日期：2020-07-01 00:00:00
abstract：BACKGROUND:Cranial artery dolichoectasia is characterized by dilated, elongated, and tortuous cranial arteries. Dolichoectasia and dolichoectatic aneurysm-particularly of the internal carotid arteries (ICAs)-are rare but can lead to stroke. We report a case of suspected recurrent acute cerebral infarction and dolichoec...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.02.153
更新日期：2019-06-01 00:00:00
abstract：BACKGROUND:The rate of cervical spinal fusion has been increasing significantly. However, there is a paucity of literature describing trends based on surgical approach using complete population databases. We investigated the approach-based trends in epidemiology, indications, and in-hospital outcomes of cervical spinal...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.02.004
更新日期：2018-05-01 00:00:00
abstract：BACKGROUND AND PURPOSE:Moyamoya disease (MMD) is a chronic cerebrovascular disorder with little known etiology. We aim to propose a new classification system for MMD from the perspective of embryology. METHODS:MMD patients' digital subtraction angiograms were retrospectively analyzed. Every angiogram was analyzed to f...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2016.08.099
更新日期：2016-12-01 00:00:00
abstract：BACKGROUND:White matter injury (WMI) has been observed after experimental intracerebral hemorrhage (ICH). The supporting clinical data have been sparse. We assessed the presence, extent, and progression of WMI in patients with ICH. METHODS:We performed a retrospective review of data from 65 consecutive patients with s...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.02.089
更新日期：2019-06-01 00:00:00
abstract：BACKGROUND:Unruptured brain arteriovenous malformations (AVMs) represent a complex disease in young healthy adults. Most often AVMs are clinically silent but also can display a neurologic syndrome due to hypoperfusion/hypometabolism in perilesional brain tissue called steal phenomenon. CASE DESCRIPTION:A 34-year-old w...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.02.167
更新日期：2019-06-01 00:00:00
abstract：BACKGROUND:Consistent data on head injury is lacking especially in the low- and middle-income countries. Our study tries to characterize patients with head injury at the emergency department of one of the few tertiary public hospitals giving neurosurgical care in the country. METHODS:A retrospective cross-sectional st...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.03.044
更新日期：2019-07-01 00:00:00
abstract：OBJECTIVE:Global neurosurgery is the practice of neurosurgery with the primary purpose of delivering timely, safe, and affordable neurosurgical care to all who need it. The aim of this study is to identify the most frequently cited articles in global neurosurgery through a bibliographic review to characterize articles ...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2020.08.084
更新日期：2020-12-01 00:00:00
abstract：OBJECTIVE:We explored the external ventricular drain (EVD) practices in Thailand. METHODS:We performed a survey-based study to describe EVD insertion, maintenance, quality improvement (QI) practices, and incidence of EVD infection. RESULTS:The study included 58 of 101 hospitals contacted (57.4% response rate), with ≥...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.02.144
更新日期：2019-06-01 00:00:00
abstract：:Dorsal arachnoid web (DAW) is a rare clinical entity with unknown etiology, and it can mimic other conditions on imaging.1,2 We present a surgical video of a patient with DAW that was misdiagnosed as ventral cord herniation. A 35-year-old woman presented with upper back pain and progressive bilateral lower extremity w...
journal_title：World neurosurgery
pub_type：
doi：10.1016/j.wneu.2020.08.011
更新日期：2020-11-01 00:00:00
abstract：OBJECTIVE:Segmental instability traditionally is investigated with flexion and extension (F/E) radiographs. We sought to determine whether motion between upright and supine (U/S) views can serve as an alternative sensitive diagnostic tool that predicts similar outcomes. METHODS:Ambispective collection of data was perf...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.06.066
更新日期：2018-09-01 00:00:00
abstract：BACKGROUND:Patients with single brain metastasis (SBM) have better outcomes after stereotactic radiosurgery (SRS). We analyzed our SRS database to evaluate possible prognostic factors in patients with SBM. METHODS:A total of 584 patients with SBM were treated with SRS at our institution (2000-2012). Study end points w...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2017.04.156
更新日期：2017-08-01 00:00:00
abstract：BACKGROUND:Electrocardiogram (ECG)-triggered angiography non-contrast-enhanced (TRANCE) imaging is useful for investigating peripheral vessel diseases; however, its efficacy for access route assessment in cerebral angiography has yet to be reported. Therefore we aimed to evaluate the efficacy of TRANCE imaging in the a...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.07.283
更新日期：2018-11-01 00:00:00
abstract：OBJECTIVE:Several studies have looked for an association between radiologic findings and neurologic outcome after cervical trauma. In the current literature, there is a paucity of evidence proving the prognostic role of soft tissue damage or bony integrity. Our objective is to determine radiologic findings related to n...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2017.02.034
更新日期：2017-05-01 00:00:00
abstract：BACKGROUND:Arachnoiditis ossificans (AO) is a rare entity characterized by the presence of calcified plaques formed by the metaplasia of arachnoid cells. Over 50 cases of AO have been reported, with predisposing factors including spinal trauma, hemorrhage, vascular abnormalities, and infection. The administration of oi...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.02.178
更新日期：2019-06-01 00:00:00
abstract：OBJECTIVE:To report on our experience with the Elekta Extend system, a relocatable frame system used in patients with brain metastases for single-session, hypofractionated, or staged hypofractionated Gamma Knife radiosurgery (GKRS); and the evaluation of its efficacy. METHODS:From March 2014 to September 2016, 856 pat...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.07.157
更新日期：2018-11-01 00:00:00
