Abstract:
Purpose:Cervical cancer is the most common gynecological cancer in India. Uniform protocol-based treatment is important for achieving optimal outcomes. We undertook a survey to investigate patterns of care with special regard to patterns of care in cervical cancer brachytherapy in India. Material and methods:A 17-question online survey was sent to radiation oncologists across India. Respondents were required to have a minimum of 1-year experience. One response per center was accepted and deemed as representative. Results:Out of 116 centers, 59 responses were generated. Two-thirds (66.1%) were from academic centers and the majority (96.6%) used high-dose-rate (HDR) brachytherapy. The centers treated an average of 255 patients per year (median 161 patients, IQR 76-355). The majority were locally advanced cancers (FIGO 2009 stage II-IV 87.5%). External beam radiotherapy (EBRT) schedules were fairly consistent, administering doses of 45-50 Gy over 5 weeks. Brachytherapy was performed towards EBRT completion by 37/59 (62%) and 43/59 (74.3%) centers used a schedule of 7 Gy × 4 fractions (HDR). Brachytherapy was commonly performed under anesthesia (spinal/general: 44% each) with ultrasound (USG) guidance (29%). Computed tomography (CT) imaging (65%) and orthogonal X-rays (35%) represented the most common imaging for planning, while point A prescription (66%) or GEC-ESTRO based parameters (35%) with manual/geometric methods represented the most common methodology for dose volume prescription and optimization. Overall treatment time (OTT) reported was within 49-56 days in 50%. Complex implants (IC + IS) were performed for more than 30% of cases by 3 centers. Conclusions:Our survey suggested a fairly uniform treatment paradigm for cervical cancer brachytherapy, with a progressive shift from 2D to 3D image-based parameters for planning, with persistence of point A based prescription. Further efforts are needed to augment and ease this transition.
journal_name
J Contemp Brachytherapyjournal_title
Journal of contemporary brachytherapyauthors
Chatterjee A,Grover S,Gurram L,Sastri S,Mahantshetty Udoi
10.5114/jcb.2019.90448subject
Has Abstractpub_date
2019-12-01 00:00:00pages
527-533issue
6eissn
1689-832Xissn
2081-2841pii
38860journal_volume
11pub_type
杂志文章abstract:PURPOSE:This study investigates the distortion of geometry of catheters and anatomy in acquired U/S images, caused by utilizing various stand-off materials for covering a transrectal bi-planar ultrasound probe in HDR and LDR prostate brachytherapy, biopsy and other interventional procedures. Furthermore, an evaluation ...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:10.5114/jcb.2011.26472
更新日期:2011-12-01 00:00:00
abstract:Purpose:Skin cancers are the most common human malignancy with increasing incidence. Currently, surgery is standard of care treatment for non-melanoma skin cancers. However, brachytherapy is a growing modality in the management of skin cancers. Therefore, we aimed to assess the outcome of patients with non-melanoma ski...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:10.5114/jcb.2018.75596
更新日期:2018-04-01 00:00:00
abstract:PURPOSE:Dose coverage is crucial for successful treatment in mono-brachytherapy. Since few and very high dose fractions are used, there is an important balance between dwell positioning outside the clinical target volume (CTV) and possible damage on adjacent normal tissue. The purpose of this study was to evaluate the ...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:10.5114/jcb.2014.45586
更新日期:2014-10-01 00:00:00
abstract:Purpose:To evaluate dose-volume relationships of target volume and critical structures in computed tomography (CT) image-based brachytherapy for head and neck cancer. Material and methods:Thirty-seven patients with mobile tongue, floor of mouth, and base of tongue cancer treated with brachytherapy (post-operative alon...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:10.5114/jcb.2017.72581
更新日期:2017-12-01 00:00:00
abstract::In order to improve oncologic outcomes in radiotherapy treatments of patients with unresectable pelvic sidewall recurrences of uterine cervical cancer, we combined high-dose-rate interstitial brachytherapy (HDR-ISBT) with newly tested hypoxic radiosensitizer Kochi oxydol-radiation therapy for unresectable carcinomas (...
journal_title:Journal of contemporary brachytherapy
pub_type:
doi:10.5114/jcb.2020.101695
更新日期:2020-12-01 00:00:00
abstract:PURPOSE:The aim of this work was to determine dose distributions for high-energy brachytherapy sources at spatial locations not included in the radial dose function gL(r) and 2D anisotropy function F(r,θ) table entries for radial distance r and polar angle θ. The objectives of this study are as follows: 1) to evaluate ...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:10.5114/jcb.2010.13715
更新日期:2010-03-01 00:00:00
abstract:Purpose:To compare post-implant dosimetrics between intraoperatively built custom-linked (IBCL) seeds and loose seeds (LS) at 24 hours and 1 month by sector analysis, and to evaluate the effect of IBCL seeds with regard to change in dosimetric parameters, in patients with prostate cancer treated with brachytherapy. Ma...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:10.5114/jcb.2020.98110
更新日期:2020-08-01 00:00:00
abstract:PURPOSE:In the study we present the initial results of palliative treatment using combined methods of HDR-BT and stent insertion in patients with advanced esophagus cancer. MATERIAL AND METHODS:Fifty patients were treated in the Great Poland Cancer Center using HDR-BT between June 2001 and December 2005 and they were ...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:
更新日期:2009-03-01 00:00:00
abstract:Purpose:The aim of this study was to compare short-term oncologic outcomes and toxicity of focal or partial low-dose-rate brachytherapy (focal/partial LDR-BT) with whole gland low-dose-rate brachytherapy (whole LDR-BT) in localized prostate cancer patients. Material and methods:Medical records of eligible patients who...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:10.5114/jcb.2020.100374
更新日期:2020-10-01 00:00:00
abstract:PURPOSE:Intracavitary brachytherapy necessitates the insertion of a tandem applicator through the cervical os into the uterine cavity. Blind insertion of the tandem may result in suboptimal tandem placement. This decreases the control of the tumor locally and may result in uterine perforation. Although routine real tim...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:10.5114/jcb.2014.55115
更新日期:2015-10-01 00:00:00
abstract:Purpose:We present a case report of treatment using interstitial and surface high-dose-rate (HDR) brachytherapy for cutaneous squamous cell carcinoma (SCC) involving the interspace of the third and fourth digits. The patient refused two-ray amputation and the lesion was not amenable for external beam radiation therapy ...
journal_title:Journal of contemporary brachytherapy
pub_type:
doi:10.5114/jcb.2020.92408
更新日期:2020-02-01 00:00:00
abstract:PURPOSE:The purpose of this study is to obtain the dosimetric parameters of the new BEBIG (60)Co brachytherapy source following by TG-43U1 recommendation with appropriate electron cutoff energy (0.521 MeV). MATERIAL AND METHODS:The new BEBIG (60)Co brachytherapy source is used to calculate the TG-43U1 parameters. EGSn...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:10.5114/jcb.2013.37419
更新日期:2013-09-01 00:00:00
abstract:PURPOSE:Low energy sources are routinely used in prostate brachytherapy. (125)I is one of the most commonly used sources. Low energy (131)Cs source was introduced recently as a brachytherapy source. The aim of this study is to compare dose distributions of (125)I, (103)Pd, and (131)Cs sources in interstitial brachyther...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:10.5114/jcb.2016.57708
更新日期:2016-02-01 00:00:00
abstract::The aim of this study is to report an uncommon case of nasal keloid treated with adaptive image-guided high-dose-rate (HDR) intracavitary brachytherapy. A 34-year-old female presented with nasal keloid after facial trauma was treated with scar resection and HDR intracavitary brachytherapy with a customized eccentric a...
journal_title:Journal of contemporary brachytherapy
pub_type:
doi:10.5114/jcb.2018.76838
更新日期:2018-06-01 00:00:00
abstract:PURPOSE:Radiotherapy for breast cancer includes different techniques and methods. The purpose of this study is to compare dosimetric calculations using TG-43 dose formalism and Varian Acuros™ BV (GBBS) dose calculation algorithm for interstitial implant of breast using metal catheters in high-dose-rate (HDR) brachyther...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:10.5114/jcb.2015.54052
更新日期:2015-08-01 00:00:00
abstract:Purpose:There is limited data to support the use of hypofractionated external beam radiation (HypoF) in combination with high-dose-rate brachytherapy (HDR). We report our quality of life (QOL) outcomes when treating intermediate and high-risk prostate cancer patients with external beam radiation (EBRT) plus HDR. Mater...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:10.5114/jcb.2018.76980
更新日期:2018-06-01 00:00:00
abstract:Purpose:To verify the accuracy and efficacy of three-dimensional printing individual template (3D-PIT) with computed tomography-magnetic resonance imaging (CT-MRI) fusion for radioactive iodine-125 (125I) seed implantation in high-grade brain gliomas. Material and methods:Between June 2017 and June 2018, 16 patients w...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:10.5114/jcb.2019.85729
更新日期:2019-06-01 00:00:00
abstract:Purpose:Inadequate procedural training is of increasing concern in resident training, especially in prostate brachytherapy (PB). Transperineal rectal spacer placement (TRSP) requires many of the same proficiencies as PB. This work describes the assessment of teaching techniques focusing on developing critical competenc...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:10.5114/jcb.2019.90984
更新日期:2019-12-01 00:00:00
abstract:PURPOSE:To outline the evolution of computerized brachytherapy treatment planning in the United States through a review of technological developments and clinical practice refinements. MATERIAL AND METHODS:A literature review was performed and interviews were conducted with six participants in the development of compu...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章,评审
doi:10.5114/jcb.2014.43131
更新日期:2014-06-01 00:00:00
abstract:Purpose:To investigate the differences in prostate-specific antigen (PSA) bounce (PB) after high-dose-rate (HDR-BT) or low-dose-rate (LDR-BT) brachytherapy alone in prostate cancer patients. Materials and methods:Ninety-four patients with localized prostate cancer (T1-T2cN0), age ranged 50-81 years, were treated with ...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:10.5114/jcb.2018.73786
更新日期:2018-02-01 00:00:00
abstract::In a field dominated by external beam radiation therapy (EBRT), both the therapeutic and technical possibilities of brachytherapy (BT) are underrated, shadowed by protons and intensity modulated radiotherapy. Decreasing expertise and indications, as well as increasing lack of specific BT training for radiation therapy...
journal_title:Journal of contemporary brachytherapy
pub_type:
doi:10.5114/jcb.2015.56769
更新日期:2015-12-01 00:00:00
abstract:PURPOSE:Three different techniques of low-dose-rate seed implantation for prostate cancer have been used since its use started in our hospital. The purpose of this study was to compare the results of the three different techniques. MATERIAL AND METHODS:The data of 305 prostate cancer patients who underwent low-dose-ra...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:10.5114/jcb.2015.48603
更新日期:2015-02-01 00:00:00
abstract:PURPOSE:Three-dimensional (3D) printing technology allows physicians to rapidly create customized devices for patients. We report our initial clinical experience using this technology to create custom applicators for vaginal brachytherapy. MATERIAL AND METHODS:Three brachytherapy patients with unique clinical needs we...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:10.5114/jcb.2016.60679
更新日期:2016-06-01 00:00:00
abstract:PURPOSE:To compare prostate contours on conventional stepping transverse image acquisitions with those on twister-based sagittal image acquisitions. MATERIAL AND METHODS:Twenty prostate cancer patients who were planned to have permanent interstitial prostate brachytherapy were prospectively accrued. A transrectal ultr...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:10.5114/jcb.2017.69807
更新日期:2017-08-01 00:00:00
abstract:PURPOSE:While there are several reports of prostate multisector dosimetry data obtained from CT or MRI scans performed at intervals ranging from 14-70 days after prostate brachytherapy (PB), there are no reports on multisector dosimetry performed in the immediate post-implant period. This study was undertaken to determ...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:10.5114/jcb.2014.42023
更新日期:2014-03-01 00:00:00
abstract::A 33-year-old premenopausal multiparous woman with the history of septate uterus was referred to the hospital with menorrhagia and inter-menstrual bleeding occurring for the last 6 months. Work-up revealed a stage IIB cervical cancer. The patient underwent curative chemo/radiotherapy. The patient's septate uterus pres...
journal_title:Journal of contemporary brachytherapy
pub_type:
doi:10.5114/jcb.2017.70996
更新日期:2017-10-01 00:00:00
abstract:PURPOSE:The incidence of non-melanoma skin cancer (NMSC) has been increasing over the past 30 years. There are different treatment options and surgical excision is the most frequent treatment due to its low rates of recurrence. Radiotherapy is an effective alternative of surgery, and brachytherapy (BT) might be a bette...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章,评审
doi:10.5114/jcb.2016.64112
更新日期:2016-12-01 00:00:00
abstract:PURPOSE:The aim of this study was to report the clinical results of uterine cervical cancer patients treated by primary radiation therapy including brachytherapy, and investigate the role of interstitial brachytherapy (ISBT). MATERIAL AND METHODS:All consecutive uterine cervical cancer patients who were treated by pri...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:10.5114/jcb.2016.62938
更新日期:2016-10-01 00:00:00
abstract:Purpose:Soft tissue sarcoma (STS) is rare but aggressive neoplasm. Interstitial brachytherapy (ISBT) alone or combined with external beam radiotherapy (EBRT) as post-operative treatment improves loco-regional (LRC) and distant control. Material and methods:Out of twenty-nine non-metastatic STS (lower limb 64%) patient...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:10.5114/jcb.2018.78994
更新日期:2018-10-01 00:00:00
abstract:Purpose:To evaluate clinical outcomes in patients with localized prostate cancer (LPC) treated with 3D conformal high-dose-rate (HDR) brachytherapy (BT) as monotherapy. Material and methods:From March 2004 to November 2017, 277 men with LPC underwent 3D conformal HDR-BT as monotherapy, with a temporary implant. The do...
journal_title:Journal of contemporary brachytherapy
pub_type: 杂志文章
doi:10.5114/jcb.2020.101685
更新日期:2020-12-01 00:00:00