Abstract：
:In desert areas, mammals such as camel and goat are exposed to harsh environmental conditions. The ambient temperature (Ta) cycles have been shown to entrain the circadian clock in the camel. In the present work, we assumed that, in the goat living in a desert biotope, Ta cycles would have the same synchronizing effect on the central clock. Therefore, the effects of Ta cycles on body temperature (Tb), locomotor activity (LA) and melatonin (Mel) rhythms as outputs of the master circadian clock have been studied. The study was performed on bucks kept first under constant conditions of total darkness (DD) and constant Ta, then maintained under DD conditions but exposed to Ta cycles with heat period during subjective day and cold period during subjective night. Finally, the Ta cycles were reversed with highest temperatures during the subjective night and the lowest temperatures during the subjective day. Under constant conditions, the circadian rhythms of Tb and LA were free running with an endogenous period of 25.3 and 25.0 hours, respectively. Ta cycles entrained the rhythms of Tb and LA to a period of exactly 24.0 hours; while when reversed, the Ta cycles led to an inversion of Tb and LA rhythms. Similarly, Ta cycles were also able to entrain Mel rhythm, by adjusting its secretion to the cooling phase before and after Ta cycles inversion. All together, these results show that the Ta cycles entrain the master circadian clock in the goat.
journal_name
J Pineal Resjournal_title
Journal of pineal researchauthors
Farsi H,Harti D,Achaâban MR,Piro M,Raverot V,Bothorel B,Ouassat M,Challet E,Pévet P,El Allali Kdoi
10.1111/jpi.12634subject
Has Abstractpub_date
2020-04-01 00:00:00pages
e12634issue
3eissn
0742-3098issn
1600-079Xjournal_volume
68pub_type
杂志文章abstract：:Optic atrophy 1 (OPA1)-related mitochondrial fusion and mitophagy are vital to sustain mitochondrial homeostasis under stress conditions. However, no study has confirmed whether OPA1-related mitochondrial fusion/mitophagy is activated by melatonin and, consequently, attenuates cardiomyocyte death and mitochondrial str...
journal_title：Journal of pineal research
pub_type： 杂志文章
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更新日期：2019-03-01 00:00:00
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journal_title：Journal of pineal research
pub_type： 杂志文章
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journal_title：Journal of pineal research
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journal_title：Journal of pineal research
pub_type： 杂志文章
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更新日期：1986-01-01 00:00:00
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journal_title：Journal of pineal research
pub_type： 杂志文章
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journal_title：Journal of pineal research
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journal_title：Journal of pineal research
pub_type： 杂志文章
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更新日期：1996-11-01 00:00:00
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journal_title：Journal of pineal research
pub_type： 杂志文章
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更新日期：2012-04-01 00:00:00
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journal_title：Journal of pineal research
pub_type： 杂志文章
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更新日期：1989-01-01 00:00:00
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journal_title：Journal of pineal research
pub_type： 杂志文章
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更新日期：2005-05-01 00:00:00
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journal_title：Journal of pineal research
pub_type： 杂志文章
doi：10.1111/j.1600-079x.1989.tb00666.x
更新日期：1989-01-01 00:00:00
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journal_title：Journal of pineal research
pub_type： 杂志文章
doi：10.1111/j.1600-079x.1999.tb00566.x
更新日期：1999-01-01 00:00:00
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journal_title：Journal of pineal research
pub_type： 杂志文章
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更新日期：2005-10-01 00:00:00
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journal_title：Journal of pineal research
pub_type： 杂志文章
doi：10.1111/j.1600-079x.1991.tb00007.x
更新日期：1991-01-01 00:00:00
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journal_title：Journal of pineal research
pub_type： 杂志文章
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更新日期：2020-10-01 00:00:00
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journal_title：Journal of pineal research
pub_type： 杂志文章,评审
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更新日期：2014-11-01 00:00:00
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journal_title：Journal of pineal research
pub_type： 杂志文章,评审
doi：10.1111/jpi.12699
更新日期：2020-10-05 00:00:00
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journal_title：Journal of pineal research
pub_type： 杂志文章
doi：10.1111/j.1600-079x.1989.tb00407.x
更新日期：1989-01-01 00:00:00
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journal_title：Journal of pineal research
pub_type： 杂志文章
doi：10.1111/j.1600-079x.1988.tb00656.x
更新日期：1988-01-01 00:00:00
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journal_title：Journal of pineal research
pub_type： 杂志文章,评审
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更新日期：2011-10-01 00:00:00
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journal_title：Journal of pineal research
pub_type： 杂志文章
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更新日期：2004-10-01 00:00:00
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journal_title：Journal of pineal research
pub_type： 杂志文章
doi：10.1111/jpi.12636
更新日期：2020-04-01 00:00:00
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journal_title：Journal of pineal research
pub_type： 杂志文章
doi：10.1111/j.1600-079X.2008.00600.x
更新日期：2009-01-01 00:00:00
abstract：:The role of antioxidants in reducing cancer initiation and progression has been highlighted in recent years. Not only antioxidants limit cancer cell growth but also, in some situations, they promote the effectiveness of conventional treatments. Melatonin, an endogenously synthesized antioxidant, reduces cell growth of...
journal_title：Journal of pineal research
pub_type： 杂志文章
doi：10.1111/j.1600-079X.2008.00585.x
更新日期：2008-10-01 00:00:00
abstract：:Transgenic rice plants overexpressing a sheep serotonin N-acetyltransferase led to an enhanced production of melatonin with various physiological effects, including seminal root elongation and resistance against cold and oxidative stress, which raises the possibility that melatonin may alter gene expression profiles i...
journal_title：Journal of pineal research
pub_type： 杂志文章
doi：10.1111/jpi.12077
更新日期：2013-11-01 00:00:00
abstract：:When organic compounds are irradiated with UV light at 254 nm, part of their covalent bonds can dissociate if the compound absorbs light at that wavelength. Therefore, photo-degradation depends strongly on the wavelength used. The energy of a light quanta at 254 nm amounts to approximately 110 kcal/mol quanta, which i...
journal_title：Journal of pineal research
pub_type： 杂志文章
doi：10.1111/j.1600-079x.2007.00536.x
更新日期：2008-05-01 00:00:00
abstract：:Melatonin secretion is an endogenous synchronizer, and it may possess some anti-aging properties. Thus we examined melatonin levels in physiological aging, in extreme senescence and in senile dementia. In healthy old (age 66-94 yr) and young subjects (age 23-39 yr) and in demented patients (age 68-91 yr) plasma melato...
journal_title：Journal of pineal research
pub_type： 杂志文章
doi：10.1111/j.1600-079X.2004.00125.x
更新日期：2004-05-01 00:00:00
abstract：:The circadian system comprises several peripheral oscillators and a central rhythm generator that, in mammals, is located in the suprachiasmatic nucleus of the hypothalamus. Expression of clock genes is a characteristic feature of the central rhythm generator and the peripheral oscillators. With regard to the rhythmic...
journal_title：Journal of pineal research
pub_type： 杂志文章
doi：10.1111/j.1600-079X.2005.00279.x
更新日期：2006-01-01 00:00:00
abstract：:Melatonin, a neurohormone that binds to two G protein-coupled receptors MT1 and MT2, is involved in pain regulation, but the distinct role of each receptor has yet to be defined. We characterized the nociceptive responses of mice with genetic inactivation of melatonin MT1 (MT1-/- ), or MT2 (MT2-/- ), or both MT1 /MT2 ...
journal_title：Journal of pineal research
pub_type： 杂志文章
doi：10.1111/jpi.12671
更新日期：2020-10-01 00:00:00
abstract：:The aim of this study was to compare the circadian control of melatonin production in teleosts. To do so, the effects of ophthalmectomy on circulating melatonin rhythms were studied along with ex vivo pineal culture in six different teleosts. Results strongly suggested that the circadian control of melatonin productio...
journal_title：Journal of pineal research
pub_type： 杂志文章
doi：10.1111/j.1600-079X.2007.00480.x
更新日期：2007-11-01 00:00:00
