Prevalence and Clinical Impact of Atrial Fibrillation in Patients with Pulmonary Embolism.

Abstract:

OBJECTIVES:Atrial fibrillation (AF) has been suggested as a cause for pulmonary embolism (PE). We aimed to explore the prevalence and clinical impact of AF in patients with PE. METHODS:Using the 2012-2014 National (Nationwide) Inpatient Sample database, we identified "adult patients with PE" as the principal discharge diagnosis. The identified admissions were stratified into two cohorts based on the presence or absence of AF. We used multivariable regression models to evaluate in-hospital mortality, length of stay, nonhome discharge, and in-hospital complications. RESULTS:The prevalence of AF among the 201,360 patients with PE was 11.62%. Patients with AF were more likely to have massive PE (odds ratio 1.59, 95% confidence interval 1.4-1.81, P < 0.001), with higher mortality (adjusted odds ratio 1.48, 95% confidence interval 1.27-1.71, P < 0.001) and a greater risk of mechanical ventilation, cardiac arrest, and nonhome discharges. The length of hospital stay in patients with PE and comorbid AF was significantly longer than those without (6.24 ± 0.10 vs 4.79 ± 0.03 days). CONCLUSIONS:AF is associated with a higher rate of massive PE, higher in-hospital mortality, a longer length of hospital stay, and a higher incidence of in-hospital complications and nonhome discharge.

journal_name

South Med J

journal_title

Southern medical journal

authors

Yang Y,Liu B,Taylor J,Huang Z,Gupta S,Thumma S,Wu L,Wang S,Everett G

doi

10.14423/SMJ.0000000000001059

subject

Has Abstract

pub_date

2020-02-01 00:00:00

pages

93-97

issue

2

eissn

0038-4348

issn

1541-8243

pii

SMJ19078

journal_volume

113

pub_type

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