The Role of Reactive Oxygen Species and Nitric Oxide in the Inhibition of Trichophyton rubrum Growth by HaCaT Cells.

abstract：:Approximately 90% of male diabetes mellitus patients have varying degrees of testicular dysfunction. The molecular mechanism underlying diabetes-induced testicular damage has not been thoroughly elucidated. In this research, we sought to determine the influence of metformin (Met) on diabetes-induced testicular injury ...

journal_title：Oxidative medicine and cellular longevity

authors： Liu Y,Yang Z,Kong D,Zhang Y,Yu W,Zha W

更新日期：2019-11-28 00:00:00

abstract：:The antiamnesic effect of 3,5-dicaffeoylquinic acid (3,5-diCQA) as the main phenolic compound in Artemisia argyi H. extract on cognitive dysfunction induced by trimethyltin (TMT) (7.1 μg/kg of body weight; intraperitoneal injection) was investigated in order to assess its ameliorating function in mice. In several beha...

journal_title：Oxidative medicine and cellular longevity

authors： Kang JY,Park SK,Guo TJ,Ha JS,Lee DS,Kim JM,Lee U,Kim DO,Heo HJ

更新日期：2016-01-01 00:00:00

abstract：:We investigated the effect of high-frequency electromagnetic fields (HF-EMFs) and 17-β-estradiol on connexins (Cxs), integrins (Ints), and estrogen receptor (ER) expression, as well as on ultrastructure of trophoblast-derived HTR-8/SVneo cells. HF-EMF, 17-β-estradiol, and their combination induced an increase of Cx40 ...

journal_title：Oxidative medicine and cellular longevity

authors： Cervellati F,Valacchi G,Lunghi L,Fabbri E,Valbonesi P,Marci R,Biondi C,Vesce F

更新日期：2013-01-01 00:00:00

abstract：:Xeroderma pigmentosum group A (XPA) is a genetic disorder in DNA nucleotide excision repair (NER) with severe neurological disorders, in which oxidative stress and disturbed melatonin metabolism may be involved. Herein we confirmed the diurnal variation of melatonin metabolites, oxidative stress markers, and antioxida...

journal_title：Oxidative medicine and cellular longevity

authors： Miyata R,Tanuma N,Sakuma H,Hayashi M

更新日期：2016-01-01 00:00:00

abstract：:In Alzheimer's disease, lipid alterations point towards peroxisomal dysfunctions. Indeed, a cortical accumulation of saturated very long chain fatty acids (VLCFAs: C22:0, C24:0, C26:0), substrates for peroxisomal β-oxidation, has been found in Alzheimer patients. This study was realized to investigate the effects of V...

journal_title：Oxidative medicine and cellular longevity

authors： Zarrouk A,Vejux A,Nury T,El Hajj HI,Haddad M,Cherkaoui-Malki M,Riedinger JM,Hammami M,Lizard G

更新日期：2012-01-01 00:00:00

abstract：:Oxidative stress (OS) and neuronal apoptosis are major pathological processes after hypoxic-ischemic encephalopathy (HIE). Colony stimulating factor 1 (CSF1), binding to CSF1 receptor (CSF1R), has been shown to reduce neuronal loss after hypoxic-ischemia- (HI-) induced brain injury. In the present study, we hypothesiz...

journal_title：Oxidative medicine and cellular longevity

authors： Hu X,Li S,Doycheva DM,Huang L,Lenahan C,Liu R,Huang J,Gao L,Tang J,Zuo G,Zhang JH

更新日期：2020-10-07 00:00:00

abstract：:Cellular senescence is a state of irreversible cell cycle arrest in response to an array of cellular stresses. An important role for senescence has been shown for a number of pathophysiological conditions that include cardiovascular disease, pulmonary fibrosis, and diseases of the skin. However, whether senescence con...

journal_title：Oxidative medicine and cellular longevity

authors： Sreekumar PG,Hinton DR,Kannan R

更新日期：2020-03-09 00:00:00

abstract：:There is accumulating evidence that blood pressure (BP) control significantly reduces the risk of future cardiovascular events in patients with essential hypertension. However, strict BP control is often difficult to maintain, and half of hypertensive patients fail to attain BP goals on single-drug therapy. Therefore,...

journal_title：Oxidative medicine and cellular longevity

authors： Bekki H,Yamamoto K,Sone M,Homma T,Nakata M,Nohara M,Fukami K,Okuda S,Yamagishi S

更新日期：2010-09-01 00:00:00

abstract：:Hemoglobin (Hb) is a family of proteins in red blood cells responsible for oxygen transport and vulnerable for oxidative damage. Hemoglobin δ subunit (HBD), a member of Hb family, is normally expressed by cells of erythroid lineage. Expression of Hb genes has been previously reported in nonerythroid and hematopoietic ...

journal_title：Oxidative medicine and cellular longevity

authors： Zuo Q,Cheng S,Huang W,Bhatti MZ,Xue Y,Zhang Y,Zhang B,Li L,Wu L,Fu J,Chen J,Li X

更新日期：2017-01-01 00:00:00

abstract：:UV-induced inflammation and reactive oxygen species formation are involved in the development of melanoma. Natural products like 5β-scymnol and CO(2)-supercritical fluid extract (CO(2)-SFE) of mussel oil contain anti-inflammatory and antioxidant properties that may aid in reducing the deleterious effects of UV radiati...

journal_title：Oxidative medicine and cellular longevity

authors： Muthusamy V,Hodges LD,Macrides TA,Boyle GM,Piva TJ

更新日期：2011-01-01 00:00:00

abstract：:Viruses play an important role in cancerogenesis. It is estimated that approximately 20% of all cancers are linked to infectious agents. The viral genes modulate the physiological machinery of infected cells that lead to cell transformation and development of cancer. One of the important adoptive responses by the canc...

journal_title：Oxidative medicine and cellular longevity

authors： Mushtaq M,Darekar S,Kashuba E

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVE:To explore the protective effects of hydrogen-rich saline on rats with smoke inhalation injury. METHODS:36 healthy male Sprague-Dawley rats were randomly divided into 3 groups (n = 12 per group): sham group (S), inhalation injury plus normal saline treatment group (I+NS), and inhalation injury plus hydrogen-...

journal_title：Oxidative medicine and cellular longevity

authors： Chen X,Liu Q,Wang D,Feng S,Zhao Y,Shi Y,Liu Q

更新日期：2015-01-01 00:00:00

abstract：:A disturbed homeostasis of cellular lipids and the resulting lipotoxicity are considered to be key contributors to many human pathologies, including obesity, metabolic syndrome, type 2 diabetes, cardiovascular diseases, and cancer. The yeast Saccharomyces cerevisiae has been successfully used for uncovering molecular ...

journal_title：Oxidative medicine and cellular longevity

authors： Mohammad K,Dakik P,Medkour Y,McAuley M,Mitrofanova D,Titorenko VI

更新日期：2018-01-31 00:00:00

abstract：:Despite tea increased plasma nonenzymatic antioxidant capacity, the European Food Safety Administration (EFSA) denied claims related to tea and its protection from oxidative damage. Furthermore, the Supplement Information Expert Committee (DSI EC) expressed some doubts on the safety of green tea extract (GTE). We perf...

journal_title：Oxidative medicine and cellular longevity

authors： Peluso I,Manafikhi H,Raguzzini A,Longhitano Y,Reggi R,Zanza C,Palmery M

更新日期：2016-01-01 00:00:00

abstract：:Hereditary hemorrhagic telangiectasia (HHT) is a vascular dysplasia caused by mutations in endoglin (ENG; HHT1) or activin receptor-like kinase (ALK1; HHT2) genes, coding for transforming growth factor-β (TGF-β) superfamily receptors. We demonstrated previously that endoglin and ALK1 interact with endothelial NO synth...

journal_title：Oxidative medicine and cellular longevity

authors： Jerkic M,Sotov V,Letarte M

更新日期：2012-01-01 00:00:00

abstract：Background:Infrasound is a major threat to global health by causing injuries of the central nervous system (CNS). However, there remains no effective therapeutic agent for preventing infrasound-caused CNS injury. 2,3,5,4'-Tetrahydroxystilbene-2-O-β-D-glycoside (THSG) exerts protective function against CNS injuries and ...

journal_title：Oxidative medicine and cellular longevity

authors： Zhou X,Yang Q,Song F,Bi L,Yuan J,Guan S,Yang Q,Wang S

更新日期：2020-01-06 00:00:00

abstract：:Intracellular reactive apoptosis and reactive oxygen species (ROS) play a crucial role in ultraviolet- (UV-) induced inflammation and aging reaction in human dermal tissues. This study determines the mechanism by which Haematococcus pluvialis extracts (HPE) and purified astaxanthin (HPA) to promote skin regeneration i...

journal_title：Oxidative medicine and cellular longevity

authors： Chou HY,Ma DL,Leung CH,Chiu CC,Hour TC,Wang HD

更新日期：2020-08-03 00:00:00

abstract：:Type 2 diabetes mellitus is a chronic metabolic disorder characterized by elevated blood glucose and/or high serum free fatty acids. Chronic hyperlipidemia causes the dysfunction of pancreatic beta cells, which is aggravated in the presence of hyperglycemia (glucolipotoxicity). Long noncoding RNAs (lncRNAs) have been ...

journal_title：Oxidative medicine and cellular longevity

authors： Kong X,Liu CX,Wang GD,Yang H,Yao XM,Hua Q,Li XY,Zhang HM,Ma MZ,Su Q,Lv K

更新日期：2019-10-14 00:00:00

abstract：:Several of the most prevalent etiological factors which contribute towards global death rates are associated with cardiovascular diseases (CVDs), which include a range of conditions such as angina, rheumatic heart disease, and venous thrombosis. Extensive research has been conducted into the role played by oxidative s...

journal_title：Oxidative medicine and cellular longevity

authors： Chen S,Jiang H,Peng H,Wu X,Fang J

更新日期：2017-01-01 00:00:00

abstract：:Serine-threonine kinase receptor-associated protein (STRAP) is a transforming growth factor β (TGF-β) receptor-interacting protein that has been implicated in both cell proliferation and cell death in response to various stresses. However, the precise roles of STRAP in these cellular processes are still unclear. The m...

journal_title：Oxidative medicine and cellular longevity

authors： Manoharan R,Seong HA,Ha H

更新日期：2018-04-19 00:00:00

abstract：:In the present study, we demonstrated that bone marrow mesenchymal stem cells (BMSCs) of the 3rd passage displayed the senescence-associated phenotypes characterized with increased activity of SA-β-gal, altered autophagy, and increased G1 cell cycle arrest, ROS production, and expression of p53 and p21Cip1/Waf1 compar...

journal_title：Oxidative medicine and cellular longevity

authors： Zhang M,Du Y,Lu R,Shu Y,Zhao W,Li Z,Zhang Y,Liu R,Yang T,Luo S,Gao M,Zhang Y,Zhang G,Liu J,Lu Y

更新日期：2016-01-01 00:00:00

abstract：:We examined in vitro antioxidant capacity of polyphenolic extract obtained from the wood of oak Quercus robur (QR), Robuvit, using TEAC (Trolox equivalent antioxidant capacity) method and the effect of its intake on markers of oxidative stress, activity of antioxidant enzymes, and total antioxidant capacity in plasma ...

journal_title：Oxidative medicine and cellular longevity

authors： Horvathova M,Orszaghova Z,Laubertova L,Vavakova M,Sabaka P,Rohdewald P,Durackova Z,Muchova J

更新日期：2014-01-01 00:00:00

abstract：Background/Aims:Polycystic ovary syndrome (PCOS) is an endocrine disorder characterized by abnormal hormone levels in peripheral blood and poor-quality oocytes. PCOS is a pathophysiological syndrome caused by chronic inflammation and oxidative stress. The aim of this study was to investigate the mechanism of melatonin ...

journal_title：Oxidative medicine and cellular longevity

authors： Yu K,Wang RX,Li MH,Sun TC,Zhou YW,Li YY,Sun LH,Zhang BL,Lian ZX,Xue SG,Liu YX,Deng SL

更新日期：2019-10-20 00:00:00

abstract：:Contrast-induced acute kidney injury (CI-AKI) is a serious complication in patients after administration of iodinated contrast media. Proper animal models of CI-AKI can help understand the mechanisms involved and prevent the disorder. We used the 5/6-nephrectomized (NE) rat to develop a CI-AKI model and to evaluate di...

journal_title：Oxidative medicine and cellular longevity

authors： Liu TQ,Luo WL,Tan X,Fang Y,Chen J,Zhang H,Yu XF,Cai JR,Ding XQ

更新日期：2014-01-01 00:00:00

abstract：:The widely used herbicide atrazine (ATR) can cause many adverse effects including immunotoxicity, but the underlying mechanisms are not fully understood. The current study investigated the role of oxidative stress and calcium homeostasis in ATR-induced immunotoxicity in mice. ATR at doses of 0, 100, 200, or 400 mg/kg ...

journal_title：Oxidative medicine and cellular longevity

authors： Gao S,Wang Z,Zhang C,Jia L,Zhang Y

更新日期：2016-01-01 00:00:00

abstract：:Picroside II, from the herb Picrorhiza scrophulariiflora Pennell, has antioxidant and anti-inflammatory activities. However, its function on severe acute pancreatitis (SAP) and molecular mechanism remains unknown. The effects of picroside II on the SAP induced by cerulean were investigated. SAP rats were treated with ...

journal_title：Oxidative medicine and cellular longevity

authors： Piao X,Liu B,Guo L,Meng F,Gao L

更新日期：2017-01-01 00:00:00

abstract：:Degradation of oxidized or oxidatively modified proteins is an essential part of the antioxidant defenses of cells. 4-Hydroxy-2-nonenal, a major reactive aldehyde formed by lipid peroxidation, causes many types of cellular damage. It has been reported that 4-hydroxy-2-nonenal-modified proteins are degraded by the ubiq...

journal_title：Oxidative medicine and cellular longevity

authors： Tsuchiya Y,Okada G,Kobayashi S,Chikuma T,Hojo H

更新日期：2011-01-01 00:00:00

abstract：:Ferroptosis is an iron-dependent type of cell death distinct from apoptosis or necrosis characterized by accumulation of reactive oxygen species. The combination of siramesine, a lysosomotropic agent, and lapatinib, a dual tyrosine kinase inhibitor (TKI), synergistically induced cell death in breast cancer cells media...

journal_title：Oxidative medicine and cellular longevity

authors： Villalpando-Rodriguez GE,Blankstein AR,Konzelman C,Gibson SB

更新日期：2019-09-17 00:00:00

abstract：:We have hypothesized that the adaptive response to low doses of ionizing radiation (IR) is mediated by oxidized cell-free DNA (cfDNA) fragments. Here, we summarize our experimental evidence for this model. Studies involving measurements of ROS, expression of the NOX (superoxide radical production), induction of apopto...

journal_title：Oxidative medicine and cellular longevity

authors： Sergeeva VA,Ershova ES,Veiko NN,Malinovskaya EM,Kalyanov AA,Kameneva LV,Stukalov SV,Dolgikh OA,Konkova MS,Ermakov AV,Veiko VP,Izhevskaya VL,Kutsev SI,Kostyuk SV

更新日期：2017-01-01 00:00:00

abstract：:Endothelial microparticles are effectors of endothelial damage; however mechanisms involved are unclear. We examined the effects of eMPs on cultured endothelial cells (ECs) and isolated vessels and investigated the role of eMP-derived reactive oxygen species (ROS) and redox signaling in these processes. eMPs were isol...

journal_title：Oxidative medicine and cellular longevity

authors： Burger D,Turner M,Munkonda MN,Touyz RM

更新日期：2016-01-01 00:00:00