Mapping initial and general recombination in scanning proton pencil beams.

abstract：:We report on a novel method for simultaneous biological optimization of treatment plans for hypoxic tumors using multiple ion species. Our previously introduced kill painting approach, where the overall cell killing is optimized on biologically heterogeneous targets, was expanded with the capability of handling differ...

journal_title：Physics in medicine and biology

authors： Sokol O,Krämer M,Hild S,Durante M,Scifoni E

更新日期：2019-02-08 00:00:00

abstract：:Carotid atherosclerosis measurements for eight subjects at baseline and 14 +/- 2 days later were examined using 1.5 T and 3.0 T magnetic resonance imaging (MRI). A single observer blinded to field strength, subject and timepoint manually segmented carotid artery wall and lumen boundaries in randomized images in five m...

journal_title：Physics in medicine and biology

authors： Vidal A,Bureau Y,Wade T,Spence JD,Rutt BK,Fenster A,Parraga G

更新日期：2008-12-07 00:00:00

abstract：:The aim of this work was to evaluate the accuracy of dose predicted in heterogeneous media by a pencil beam (PB), a collapsed cone (CC) and a Monte Carlo (MC) algorithm. For this purpose, a simple multi-layer phantom composed of Styrofoam and white polystyrene was irradiated with 10 x 10 cm2 as well as 20 x 20 cm2 ope...

journal_title：Physics in medicine and biology

authors： Krieger T,Sauer OA

更新日期：2005-03-07 00:00:00

abstract：:Two different classifiers, an artificial neural network (ANN) and a hybrid system (one step rule-based method followed by an artificial neural network) have been investigated to merge computer-extracted features in the task of differentiating between malignant and benign masses. A database consisting of 65 cases (38 m...

journal_title：Physics in medicine and biology

authors： Huo Z,Giger ML,Metz CE

更新日期：1999-10-01 00:00:00

abstract：:This study looks at blood flow in four different human right coronary arteries (RCAs), which have been reconstructed from bi-plane angiograms. A generalized power-law model of blood viscosity is used to study the blood flow at a particular point in the cardiac cycle. Large differences are found in the wall shear stres...

journal_title：Physics in medicine and biology

authors： Johnston BM,Johnston PR

更新日期：2007-05-07 00:00:00

abstract：:Optical computed tomography (optical-CT) of 3D radiation dosimeters is a promising avenue for delivering an economic and reliable quality control of radiotherapy treatments such as intensity modulated radiotherapy, brachytherapy and stereotactic radiosurgery. The main problems in transferring 3D dosimeters to clinical...

journal_title：Physics in medicine and biology

authors： Krstajić N,Doran SJ

更新日期：2007-06-07 00:00:00

abstract：:A novel meshless reconstruction algorithm for digital tomosynthesis (DT) is presented and assessed against experimental data. The algorithm does not require a three-dimensional grid or mesh allocation and performs a slice-by-slice reconstruction where each slice position can be chosen at runtime. The methodology is ba...

journal_title：Physics in medicine and biology

authors： Soloviev VY,Renforth KL,Dirckx CJ,Wells SG

更新日期：2020-04-20 00:00:00

abstract：:A function called Gx(L) was introduced by the International Commission on Radiation Units and Measurements (ICRU) Report-87 to facilitate measurement of cumulative dose for CT scans within long phantoms as recommended by the American Association of Physicists in Medicine (AAPM) TG-111. The Gx(L) function is equal to t...

journal_title：Physics in medicine and biology

authors： Abuhaimed A,Martin CJ,Sankaralingam M,Gentle DJ

更新日期：2015-07-21 00:00:00

abstract：:The process of organ motion correction in scintigraphy is analysed in the frequency domain. The sequence of the chi- and gamma- coordinates registered during scintigraphic recording is converted to a frequency spectrum by a discrete Fourier transform. In the frequency domain motion correction is performed by linear fi...

journal_title：Physics in medicine and biology

authors： Schmidlin P

更新日期：1975-05-01 00:00:00

abstract：:Correct classification of cystoscopy images depends on the interpreter's experience. Bladder cancer is a common lesion that can only be confirmed by biopsying the tissue, therefore, the automatic identification of tumors plays a significant role in early stage diagnosis and its accuracy. To our best knowledge, the use...

journal_title：Physics in medicine and biology

authors： Freitas NR,Vieira PM,Lima E,Lima CS

更新日期：2018-02-02 00:00:00

abstract：:Echocardiography (echo) is a widely available method to obtain images of the heart; however, echo can suffer due to the presence of artefacts, high noise and a restricted field of view. One method to overcome these limitations is to use multiple images, using the 'best' parts from each image to produce a higher qualit...

journal_title：Physics in medicine and biology

authors： Yao C,Simpson JM,Schaeffter T,Penney GP

更新日期：2011-09-21 00:00:00

abstract：:In this paper, Novikov's inversion formula of the attenuated two-dimensional (2D) Radon transform is applied to the reconstruction of attenuated fan-beam projections acquired with equal detector spacing and of attenuated cone-beam projections acquired with a flat planar detector and circular trajectory. The derivation...

journal_title：Physics in medicine and biology

authors： Huang Q,Zeng GL,You J,Gullberg GT

更新日期：2005-05-21 00:00:00

abstract：:As known, in cancer therapy with ion beams the relative biological effectiveness (RBE) of ions changes in the course of their propagation in tissues. Such changes are caused not only by increasing the linear energy transfer (LET) of beam particles with the penetration depth towards the Bragg peak, but also by nuclear ...

journal_title：Physics in medicine and biology

authors： Dewey S,Burigo L,Pshenichnov I,Mishustin I,Bleicher M

更新日期：2017-06-27 00:00:00

abstract：:Various forms of GAFChromic film have been used for several years as radiographic media for measuring dose distributions of brachytherapy sources and small radiation fields. Upon irradiation the film changes colour and darkens with time post-irradiation. The darkening is most rapid in the first 24 h, and it has been s...

journal_title：Physics in medicine and biology

authors： Reinstein LE,Gluckman GR,Meek AG

更新日期：1998-10-01 00:00:00

abstract：:It is not feasible to define very small or complex organs and tissues in the current voxel-type adult reference computational phantoms of the International Commission on Radiological Protection (ICRP), which limit dose coefficients for weakly penetrating radiations. To address the problem, the ICRP is converting the v...

journal_title：Physics in medicine and biology

authors： Kim HS,Yeom YS,Nguyen TT,Choi C,Han MC,Lee JK,Kim CH,Zankl M,Petoussi-Henss N,Bolch WE,Lee C,Qiu R,Eckerman K,Chung BS

更新日期：2017-03-21 00:00:00

abstract：:In order to enable a detailed analysis of radio frequency (RF) absorption in the human middle and inner ear organs, a numerical model of these organs was developed at a spatial resolution of 0.1 mm, based on a real human tissue sample. The dielectric properties of the liquids (perilymph and endolymph) inside the bony ...

journal_title：Physics in medicine and biology

authors： Schmid G,Uberbacher R,Samaras T,Jappel A,Baumgartner WD,Tschabitscher M,Mazal PR

更新日期：2007-04-07 00:00:00

abstract：:Maximum likelihood estimation (MLE) is presented as a statistical tool to evaluate the contribution of measurement error to any measurement series where the same quantity is measured using different independent methods. The technique was tested against artificial data sets; generated for values of underlying variation...

journal_title：Physics in medicine and biology

authors： Sage JP,Mayles WP,Mayles HM,Syndikus I

更新日期：2014-10-21 00:00:00

abstract：:The results of optimization of inverse treatment plans depend on a choice of the objective function. Even when the optimal solution for a given cost function can be obtained, a better solution may exist for a given clinical scenario and it could be obtained with a revised objective function. In the approach presented ...

journal_title：Physics in medicine and biology

authors： Bednarz G,Michalski D,Anne PR,Valicenti RK

更新日期：2004-06-21 00:00:00

abstract：:The sulphuric acid used for the preparation of the Fricke dosimeter solution may contain trace impurities that can affect the yield of ferric ions. Two methods, pre-irradiation or oxidation with hydrogen peroxide, have been proposed to reduce the influence of these impurities. Fricke users sometimes omit this treatmen...

journal_title：Physics in medicine and biology

authors： Palm A,Mattsson O

更新日期：2000-09-01 00:00:00

abstract：:Scattered radiation from within the treatment head can contribute significant dose to all parts of a radiotherapy treatment field. A multileaf collimator may be used to create an arbitrarily shaped field, and may also be used, under dynamic control, to modulate the beam intensity over the field. This method of intensi...

journal_title：Physics in medicine and biology

authors： Hounsell AR,Wilkinson JM

更新日期：1997-09-01 00:00:00

abstract：:A quantitative comparison of two full three-dimensional (3D) gel dosimetry techniques was assessed in a clinical setting: radiochromic gel dosimetry with an in-house developed optical laser CT scanner and polymer gel dosimetry with magnetic resonance imaging (MRI). To benchmark both gel dosimeters, they were exposed t...

journal_title：Physics in medicine and biology

authors： Vandecasteele J,De Deene Y

更新日期：2013-09-21 00:00:00

abstract：:As a prerequisite for clinical treatments it was necessary to characterize the Elekta 1.5 T MRI-linac 7 MV FFF radiation beam. Following acceptance testing, beam characterization data were acquired with Semiflex 3D (PTW 31021), microDiamond (PTW 60019), and Farmer-type (PTW 30013 and IBA FC65-G) detectors in an Elekta...

journal_title：Physics in medicine and biology

authors： Woodings SJ,Bluemink JJ,de Vries JHW,Niatsetski Y,van Veelen B,Schillings J,Kok JGM,Wolthaus JWH,Hackett SL,van Asselen B,van Zijp HM,Pencea S,Roberts DA,Lagendijk JJW,Raaymakers BW

更新日期：2018-04-19 00:00:00

abstract：:Picking geometrically relevant atlases from the whole training set is crucial to multi-atlas based image segmentation, especially with extensive data of heterogeneous quality in the Big Data era. Unfortunately, there is very limited understanding of how currently used image similarity criteria reveal geometric relevan...

journal_title：Physics in medicine and biology

authors： Zhao T,Ruan D

更新日期：2016-06-07 00:00:00

abstract：:Respiratory gating based on external surrogates is performed in many clinics. We have developed a new technique for treatment verification using an electronic portal imaging device (EPID) in cine mode for gated 3D conformal therapy. Implanted radiopaque fiducial markers inside or near the target are required for this ...

journal_title：Physics in medicine and biology

authors： Berbeco RI,Neicu T,Rietzel E,Chen GT,Jiang SB

更新日期：2005-08-21 00:00:00

abstract：:Polymer gel dosimetry aims to provide three-dimensional images of radiation therapy dose distributions in irradiated aqueous gels. The first gels required manufacture in an oxygen-free environment, but later the MAGIC formulation was introduced, which could be made in normal atmospheric conditions. Here we report our ...

journal_title：Physics in medicine and biology

authors： Luci JJ,Whitney HM,Gore JC

更新日期：2007-05-21 00:00:00

abstract：:In this paper, the influence of a dynamic variation in the ambient pressure on the subharmonic response of phospholipid-coated microbubbles was investigated. The ambient pressure in water was modulated by a 2.5 kHz acoustic wave with a peak amplitude of 15 kPa. We investigated the fundamental and subharmonic emissions...

journal_title：Physics in medicine and biology

authors： Faez T,Renaud G,Defontaine M,Calle S,de Jong N

更新日期：2011-10-07 00:00:00

abstract：:Tumour histological grade has prognostic implications in breast cancer. Tumour features in dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) and T2-weighted (T2W) imaging can provide related and complementary information in the analysis of breast lesions to improve MRI-based histological status prediction...

journal_title：Physics in medicine and biology

authors： Fan M,Liu Z,Xie S,Xu M,Wang S,Gao X,Li L

更新日期：2019-10-23 00:00:00

abstract：:The effects of radiation damage, tumour repopulation and cell sublethal damage repair and the possibility of extracting information about the model parameters describing them are investigated in this work. Previously published data on two different cultured cell lines were analysed with the help of a tumour control pr...

journal_title：Physics in medicine and biology

authors： Stavrev P,Weldon M,Warkentin B,Stavreva N,Fallone BG

更新日期：2005-07-07 00:00:00

abstract：:Three major linear accelerator vendors offer gantry-mounted single (monoscopic) x-ray imagers. The use of monoscopic imaging to estimate three-dimensional (3D) target positions has not been fully explored. The purpose of this work is to develop and investigate a robust monoscopic method for real-time tumour tracking, ...

journal_title：Physics in medicine and biology

authors： Cho B,Suh Y,Dieterich S,Keall PJ

更新日期：2008-06-07 00:00:00

abstract：:Assessment of radiation absorbed dose to internal organs of the body from the intake of radionuclides or, in the medical setting through the injection of radiopharmaceuticals, is generally performed based upon reference biokinetic models or patient imaging data, respectively. Biokinetic models estimate the time course...

journal_title：Physics in medicine and biology

authors： Schwarz BC,Godwin WJ,Wayson MB,Dewji SA,Jokisch DW,Lee C,Bolch WE

更新日期：2020-11-03 00:00:00