Fast laser scanning optical-CT apparatus for 3D radiation dosimetry.

abstract：:This paper presents a description of tests carried out to compare the behaviour of five algorithms in inverse radiation therapy planning: (1) The Dynamically Penalized Likelihood (DPL), an algorithm based on statistical estimation theory; (2) an accelerated version of the same algorithm: (3) a new fast adaptive simula...

journal_title：Physics in medicine and biology

authors： Llacer J,Solberg TD,Promberger C

更新日期：2001-10-01 00:00:00

abstract：:Four-dimensional (4D) methods strive to achieve highly conformal radiotherapy, particularly for lung and breast tumours, in the presence of respiratory-induced motion of tumours and normal tissues. Four-dimensional radiotherapy accounts for respiratory motion during imaging, planning and radiation delivery, and requir...

journal_title：Physics in medicine and biology

authors： Vedam SS,Keall PJ,Kini VR,Mostafavi H,Shukla HP,Mohan R

更新日期：2003-01-07 00:00:00

abstract：:Histotripsy is an ultrasound ablation method that depends on the initiation of a cavitation bubble cloud to fractionate soft tissue. Although previous work has provided significant insight into the process of intrinsic threshold histotripsy, the majority of these studies have used highly focused (i.e. f-number  <  0.6...

journal_title：Physics in medicine and biology

authors： Vlaisavljevich E,Gerhardson T,Hall T,Xu Z

更新日期：2017-02-21 00:00:00

abstract：:Over the last two years we have evaluated paediatric patient doses in projection radiography derived from exposure level (EL) in computed radiography (CR) in a large university hospital. Entrance surface air kerma (ESAK) for 3501 paediatric examinations was calculated from the EL, which is a dose index parameter relat...

journal_title：Physics in medicine and biology

authors： Vano E,Martinez D,Fernandez JM,Ordiales JM,Prieto C,Floriano A,Ten JI

更新日期：2008-06-21 00:00:00

abstract：:The use of liquid ionization chambers in radiotherapy has grown during the past few years. While for air ionization chambers the k(TP) correction for air mass density due to pressure and temperature variations is well known, less work has been done on the case of liquid ionization chambers, where there is still the ne...

journal_title：Physics in medicine and biology

authors： Gómez F,González-Castaño D,Díaz-Botana P,Pardo-Montero J

更新日期：2014-06-07 00:00:00

abstract：:We assume that the data bits of a pixel in digital images can be divided into signal and noise bits. The signal bits occupy the most significant part of the pixel and the noise bits the least significant part. The signal part of each pixel are correlated while the noise parts are uncorrelated. Two statistical methods,...

journal_title：Physics in medicine and biology

authors： Chuang KS,Huang HK

更新日期：1992-02-01 00:00:00

abstract：:We developed and validated a Monte-Carlo-based application (RAYDOSE) to generate patient-specific 3D dose maps on the basis of pre-treatment imaging studies. A CT DICOM image is used to model patient geometry, while repeated PET scans are employed to assess radionuclide kinetics and distribution at the voxel level. In...

journal_title：Physics in medicine and biology

authors： Marcatili S,Pettinato C,Daniels S,Lewis G,Edwards P,Fanti S,Spezi E

更新日期：2013-04-21 00:00:00

abstract：:The (83)Kr magnetic resonance (MR) relaxation time T(1) of krypton gas in contact with model surfaces was previously found to be highly sensitive to surface composition, surface-to-volume ratio, and surface temperature. The work presented here explored aspects of pulmonary (83)Kr T(1) relaxation measurements in excise...

journal_title：Physics in medicine and biology

authors： Stupic KF,Elkins ND,Pavlovskaya GE,Repine JE,Meersmann T

更新日期：2011-07-07 00:00:00

abstract：:Backscatter factors for orthovoltage x-ray beams are fitted with the expression BSF = 1 + ms/(s + n), where s is field size and m and n are adjustable parameters. The accuracy is better than 0.5%. Good results were also obtained for Cs-137 gamma rays at depth 0.12 cm and Co-60 gamma rays at depth 0.5 cm using the same...

journal_title：Physics in medicine and biology

authors： Xiao Y,Bjärngard B

更新日期：1998-05-01 00:00:00

abstract：:Factors affecting the accuracy of the in vivo measurement of cutaneous pigments and blood oxygenation by reflectance spectrophotometry have been examined. It was found that stray light, the amounts of haemoglobin and melanin, and the level of blood oxygenation all contributed to the measured reflectance and had to be ...

journal_title：Physics in medicine and biology

authors： Hajizadeh-Saffar M,Feather JW,Dawson JB

更新日期：1990-09-01 00:00:00

abstract：:Fluorescence molecular tomography (FMT) is widely used in preclinical oncology research. FMT is the only imaging technique able to provide 3D distribution of fluorescent probes within thick highly scattering media. However, its integration into clinical medicine has been hampered by its low spatial resolution caused b...

journal_title：Physics in medicine and biology

authors： Nouizi F,Kwong TC,Ruiz J,Cho J,Chan YW,Ikemura K,Erkol H,Sampathkumaran U,Gulsen G

更新日期：2019-01-22 00:00:00

abstract：:An expression for the noise power spectrum of images reconstructed by the discrete filtered backprojection algorithm has been derived. The formulation explicitly includes sampling within the projections, angular sampling, and the two-dimensional sampling implicit in the discrete representation of the image. The effect...

journal_title：Physics in medicine and biology

authors： Kijewski MF,Judy PF

更新日期：1987-05-01 00:00:00

abstract：:The aim of the study is to verify the fundamental assumption in the monitor source method, i.e. uniform fractional count loss across the field of view (FOV), and to introduce a revised monitor source method for SPECT deadtime correction that minimally interferes with the clinical protocol. SPECT images of non-uniform ...

journal_title：Physics in medicine and biology

authors： Siman W,Silosky M,Kappadath SC

更新日期：2015-02-07 00:00:00

abstract：:We propose a hybrid multiobjective (MO) evolutionary optimization algorithm (MOEA) for intensity-modulated radiotherapy inverse planning and apply it to optimize the number of incident beams, their orientations and intensity profiles. The algorithm produces a set of efficient solutions, which represent different clini...

journal_title：Physics in medicine and biology

authors： Schreibmann E,Lahanas M,Xing L,Baltas D

更新日期：2004-03-07 00:00:00

abstract：:Mean glandular dose (MGD) is the figure of merit to assess breast dose after a mammographic acquisition. The use of normalized MGD obtained from Monte Carlo computations with measured incident air kerma determines the MGD delivered to patients. The Geant4 Application for Tomographic Emission (GATE) toolkit is a modern...

journal_title：Physics in medicine and biology

authors： Myronakis ME,Zvelebil M,Darambara DG

更新日期：2013-04-07 00:00:00

abstract：:Developments in positron emission tomography (PET) technology have resulted in systems with finer detector elements designed to further improve spatial resolution. However, there is a limit to what extent reducing detector element size will improve spatial resolution in PET. The spatial resolution of PET imaging is li...

journal_title：Physics in medicine and biology

authors： Levin CS,Hoffman EJ

更新日期：1999-03-01 00:00:00

abstract：:Voltage-sensitive dyes are an important tool in visualizing electrical activity in cardiac tissue. Until today, they have mainly been applied in cardiac electrophysiology to subsurface imaging. In the present study, we assess different imaging methods used in optical tomography with respect to their effectiveness in v...

journal_title：Physics in medicine and biology

authors： Bernus O,Wellner M,Mironov SF,Pertsov AM

更新日期：2005-01-21 00:00:00

abstract：:Patient motion is an important factor affecting the quality of external beam radiotherapy in breast patients. We analyse the motion of a dense set of surface points on breast patients throughout their treatment schedule to assess the magnitude and stability of motion, in particular, with respect to breast volume. We u...

journal_title：Physics in medicine and biology

authors： Price GJ,Sharrock PJ,Marchant TE,Parkhurst JM,Burton D,Jain P,Price P,Moore CJ

更新日期：2009-11-07 00:00:00

abstract：:We investigate the effect of multiple scattering on the optical coherence tomography (OCT) signal and the Doppler OCT signal of flowing blood. Doppler OCT measurements at 1300 nm are performed on flowing diluted porcine blood with hematocrit ranging between 0% and 15%. Measured blood hematocrit and mean red blood cell...

journal_title：Physics in medicine and biology

authors： Kalkman J,Bykov AV,Streekstra GJ,van Leeuwen TG

更新日期：2012-04-07 00:00:00

abstract：:This paper presents a method to experimentally validate the beam quality correction factors (kQ) tabulated in IAEA TRS-398 for proton beams and to determine the kQ of non-tabulated ionization chambers (based on the already tabulated values). The method is based exclusively on ionometry and it consists in comparing the...

journal_title：Physics in medicine and biology

authors： Gomà C,Hofstetter-Boillat B,Safai S,Vörös S

更新日期：2015-04-21 00:00:00

abstract：:Effects of different scatter compensation methods incorporated in fully 3D iterative reconstruction are investigated. The methods are: (i) the inclusion of an 'ideal scatter estimate' (ISE); (ii) like (i) but with a noiseless scatter estimate (ISE-NF); (iii) incorporation of scatter in the point spread function during...

journal_title：Physics in medicine and biology

authors： Beekman FJ,Kamphuis C,Frey EC

更新日期：1997-08-01 00:00:00

abstract：:The purpose of this study is to calculate Pareto surfaces in multi-criteria radiation treatment planning and to analyse the dependency of the Pareto surfaces on the objective functions used for the volumes of interest. We develop a linear approach that allows us to calculate truly Pareto optimal treatment plans, and w...

journal_title：Physics in medicine and biology

authors： Craft D,Halabi T,Bortfeld T

更新日期：2005-12-21 00:00:00

abstract：:Curves relating beam energy, scattering foil thickness, central-axis depth-dose, and beam flatness have been generated using data taken on a Siemens 200A betatron. The curve set allows a single combination of tungsten foil thickness and electron beam energy to be chosen that will provide the optimum depth-dose distrib...

journal_title：Physics in medicine and biology

authors： Marbach JR,Almond PR

更新日期：1981-05-01 00:00:00

abstract：:Respiratory motion in emission tomography leads to reduced image quality. Developed correction methodology has been concentrating on the use of respiratory synchronized acquisitions leading to gated frames. Such frames, however, are of low signal-to-noise ratio as a result of containing reduced statistics. In this wor...

journal_title：Physics in medicine and biology

authors： Lamare F,Ledesma Carbayo MJ,Cresson T,Kontaxakis G,Santos A,Le Rest CC,Reader AJ,Visvikis D

更新日期：2007-09-07 00:00:00

abstract：:Various lead attenuation techniques to determine the fast neutron sensitivity kU of a photon dosemeter are reviewed and a modified method is proposed to determine the kU value of a commercially available Geiger--Müller detector. The dependence on the 'effective' photon energy of the gamma-component of the mixed n--gam...

journal_title：Physics in medicine and biology

authors： Hough JH

更新日期：1979-07-01 00:00:00

abstract：:A Monte Carlo computational model of a fluoroscopic imaging chain was used for deriving optimal technique factors for paediatric fluoroscopy. The optimal technique was defined as the one that minimizes the absorbed dose (or dose rate) in the patient with a constraint of constant image quality. Image quality was assess...

journal_title：Physics in medicine and biology

authors： Tapiovaara MJ,Sandborg M,Dance DR

更新日期：1999-02-01 00:00:00

abstract：:The aim of this paper is to determine the dosimetric impact of trace elements in human tissues for low-energy photon sources used in brachytherapy. Monte Carlo dose calculations were used to investigate the dosimetric effect of trace elements present in normal or cancerous human tissues. The effect of individual trace...

journal_title：Physics in medicine and biology

authors： White SA,Landry G,van Gils F,Verhaegen F,Reniers B

更新日期：2012-06-07 00:00:00

abstract：:Kilo-voltage (KV) cone-beam computed tomography (CBCT) unit mounted onto a linear accelerator treatment system, often referred to as on-board imager (OBI), plays an increasingly important role in image-guided radiation therapy. While the FDK algorithm is currently used for reconstructing images from clinical OBI data,...

journal_title：Physics in medicine and biology

authors： Han X,Pearson E,Pelizzari C,Al-Hallaq H,Sidky EY,Bian J,Pan X

更新日期：2015-06-21 00:00:00

abstract：:In order to measure in vivo resistivity of tissues in the thorax, the possibility of combining anatomical data extracted from high-resolution images with multiple-electrode impedance measurements, a priori knowledge of the range of tissue resistivities, and a priori data on the instrumentation noise is assessed in thi...

journal_title：Physics in medicine and biology

authors： Eyüboğlu BM,Pilkington TC,Wolf PD

更新日期：1994-01-01 00:00:00

abstract：:Medulloblastoma treatment involves irradiation of the entire central nervous system, i.e. craniospinal irradiation (CSI). This is associated with the significant exposure of large volumes of healthy tissue and there is growing concern regarding treatment-associated side effects. The current study compares out-of-field...

journal_title：Physics in medicine and biology

authors： De Saint-Hubert M,Verellen D,Poels K,Crijns W,Magliona F,Depuydt T,Vanhavere F,Struelens L

更新日期：2017-07-07 00:00:00