Anal HPV detection in men who have sex with men living with HIV who report no recent anal sexual behaviours: baseline analysis of the Anal Cancer Examination (ACE) study.

Abstract:

OBJECTIVES:Men who have sex with men (MSM) living with HIV are at high risk of infection with high-risk human papillomavirus (HPV), the cause of anal cancer. We assess whether anal HPV DNA detection is related to recent anal sexual activity, what types of anal sexual activity or the persistence of HPV genotypes. METHODS:We analysed anal swabs taken at the baseline of a 2-year prospective anal cancer screening study of MSM living with HIV from four HIV clinics in Melbourne, Australia. Anal HPV detection was stratified by age and anal sexual behaviours. RESULTS:281 anal swabs were included in the analysis. The majority (80%, 95% CI 75 to 84) of men were positive for any HPV; 59% (95% CI 53 to 65) were positive for high-risk HPV (hr-HPV) genotypes; and 31% (95% CI 26 to 36) men were positive for HPV 16 and/or 18 with no significant differences according to age groups (p>0.261). In men who reported no receptive anal sexual activity in the last six months (22%), hr-HPV was found in 53% (95% CI 41 to 65) for no anal sexual activity versus. 60% (95% CI 54 to 67) for anal sexual activity (p=0.320). HPV 16 and/or 18 was found in 26% (95% CI 16 to 38) for no anal sexual activity versus. 32% (95% CI 27 to 39) for anal sexual activity (p=0.320). CONCLUSIONS:Anal HPV in MSM living with HIV is detected in the majority of men throughout all age groups. Anal HPV detection remains high even in men reporting no anal sexual activity in the preceding six months.

journal_name

Sex Transm Infect

authors

Ong JJ,Chen M,Tabrizi SN,Cornall A,Garland SM,Jin F,Tee BK,Eu B,Fairley CK

doi

10.1136/sextrans-2015-052121

subject

Has Abstract

pub_date

2016-08-01 00:00:00

pages

368-70

issue

5

eissn

1368-4973

issn

1472-3263

pii

sextrans-2015-052121

journal_volume

92

pub_type

杂志文章,多中心研究
  • Human papillomavirus (HPV) infection in heterosexual South African men attending sexual health services: associations between HPV and HIV serostatus.

    abstract:OBJECTIVES:To investigate the distribution of human papillomavirus (HPV) genotypes and determine the associations between HPV infection and HIV coinfection in sexually active heterosexual men with anogenital warts (GW), male urethral discharge or asymptomatic men. METHODS:Valid specimens for HPV genotyping were obtain...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章,多中心研究

    doi:10.1136/sti.2009.037598

    authors: Müller EE,Chirwa TF,Lewis DA

    更新日期:2010-06-01 00:00:00

  • A cross-sectional survey of attitudes to HIV risk and rapid HIV testing among clients of sex workers in Switzerland.

    abstract:OBJECTIVES:To assess attitudes to HIV risk and acceptability of rapid HIV testing among clients of street-based female sex workers (FSW) in Lausanne, Switzerland, where HIV prevalence in the general population is 0.4%. METHODS:The authors conducted a cross-sectional study in the red light district of Lausanne for five...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章

    doi:10.1136/sextrans-2012-050489

    authors: Darling KE,Diserens EA,N'garambe C,Ansermet-Pagot A,Masserey E,Cavassini M,Bodenmann P

    更新日期:2012-10-01 00:00:00

  • The chlamydia screening studies: rationale and design.

    abstract:BACKGROUND:Screening has been recommended to reduce the prevalence and morbidity associated with genital chlamydia infection in the United Kingdom. METHODS:We describe the rationale and study design of the Chlamydia Screening Studies (ClaSS), a collaborative project designed to evaluate screening outside genitourinary...

    journal_title:Sexually transmitted infections

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1136/sti.2003.006197

    authors: Low N,McCarthy A,Macleod J,Salisbury C,Horner PJ,Roberts TE,Campbell R,Herring A,Skidmore S,Sanford E,Sterne JA,Davey Smith G,Graham A,Huengsberg M,Ross J,Egger M

    更新日期:2004-10-01 00:00:00

  • Prevalence of Chlamydia trachomatis: results from the first national population-based survey in France.

    abstract:BACKGROUND:Few studies have estimated Chlamydia trachomatis (CT) prevalence in the general population, most prevalence studies being based on people already attending healthcare settings. OBJECTIVES:To estimate the prevalence of CT in France, assess the feasibility of home sampling without any face-to-face interventio...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章,多中心研究

    doi:10.1136/sti.2009.038752

    authors: Goulet V,de Barbeyrac B,Raherison S,Prudhomme M,Semaille C,Warszawski J,CSF group.

    更新日期:2010-08-01 00:00:00

  • Antiseptic mouthwash against pharyngeal Neisseria gonorrhoeae: a randomised controlled trial and an in vitro study.

    abstract:BACKGROUND:Gonorrhoea is increasing among men who have sex with men (MSM). We aimed to determine whether Listerine, a commercial mouthwash product, has an inhibitory effect against Neisseria gonorrhoeae in a randomised controlled trial (RCT) and an in vitro study, and therefore may be a potentially useful agent for gon...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章,随机对照试验

    doi:10.1136/sextrans-2016-052753

    authors: Chow EP,Howden BP,Walker S,Lee D,Bradshaw CS,Chen MY,Snow A,Cook S,Fehler G,Fairley CK

    更新日期:2017-03-01 00:00:00

  • Rural sex work in Cambodia: work characteristics, risk behaviours, HIV, and syphilis.

    abstract:OBJECTIVE:To identify prevalence and risks factors for syphilis and HIV among rural female sex workers (FSWs) in Cambodia and to describe differences between rural and urban FSWs. METHODS:Interviews and sera were collected from 114 FSWs and tested for HIV using the Serodia-HIV test and positives confirmed with the enz...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章

    doi:10.1136/sti.79.4.e2

    authors: Sopheab H,Gorbach PM,Gloyd S,Leng HB

    更新日期:2003-08-01 00:00:00

  • The concentration of sexual behaviours in the USA: a closer examination of subpopulations.

    abstract:OBJECTIVE:To examine the frequency of three sexual behaviours from the most active to the least active members of the population in various subpopulations using measures of inequality. METHODS:Data from a US national probability sample of the population aged 15-44 years (National Survey of Family Growth) were used. Gi...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章

    doi:10.1136/sti.2010.042283

    authors: Leichliter JS,Chesson HW,Sternberg M,Aral SO

    更新日期:2010-12-01 00:00:00

  • Anonymous partnerships among MSM and transgender women (TW) recently diagnosed with HIV and other STIs in Lima, Peru: an individual-level and dyad-level analysis.

    abstract:OBJECTIVES:Partner notification (PN) following sexually transmitted disease (STI) diagnosis is a key strategy for controlling HIV/STI transmission. Anonymous partnerships are an important barrier to PN and often associated with high-risk sexual behaviour. Limited research has examined the profile of men who have sex wi...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章

    doi:10.1136/sextrans-2015-052310

    authors: Perez-Brumer AG,Oldenburg CE,Segura ER,Sanchez J,Lama JR,Clark JL

    更新日期:2016-11-01 00:00:00

  • Demographic changes and trends in risk behaviours, HIV and other sexually transmitted infections among female sex workers in Bangalore, India involved in a focused HIV preventive intervention.

    abstract::The primary objectives of this study were to assess the changing demographic characteristics of female sex workers (FSWs) in the urban Bangalore district, India, and trends in programme coverage, HIV/sexually transmitted infection prevalence rates and condom use. Cross-sectional, integrated behavioural and biological ...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章

    doi:10.1136/sextrans-2013-051203

    authors: Jayaraman GC,Kumar S,Isac S,Javalkar P,Gowda PR,Raghunathan N,Gowda CS,Bhattacharjee P,Moses S,Blanchard JF

    更新日期:2013-12-01 00:00:00

  • Effect of weighting for sampling and non-response on estimates of STI prevalence in the third British National Survey of Sexual Attitudes and Lifestyles (Natsal-3).

    abstract:OBJECTIVES:In addition to researcher-designed sampling biases, population-representative surveys for biomarker measurement of STIs often have substantial missingness due to non-contact, non-consent and other study-implementation issues. STI prevalence estimates may be biased if this missingness is related to STI risk. ...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章

    doi:10.1136/sextrans-2019-054342

    authors: Harling G,Copas A,Clifton S,Johnson AM,Field N,Sonnenberg P,Mercer CH

    更新日期:2020-11-01 00:00:00

  • SMS reminders improve re-screening in women and heterosexual men with chlamydia infection at Sydney Sexual Health Centre: a before-and-after study.

    abstract:BACKGROUND:In 2009, Sydney Sexual Health Centre implemented a short message service (SMS) reminder system to improve re-screening after chlamydia infection. SMS reminders were sent at 3 months recommending the patient make an appointment for a re-screen. METHODS:Using a before-and-after study, the authors compared the...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章

    doi:10.1136/sextrans-2011-050370

    authors: Guy R,Wand H,Knight V,Kenigsberg A,Read P,McNulty AM

    更新日期:2013-02-01 00:00:00

  • The superiority of polymerase chain reaction over an amplified enzyme immunoassay for the detection of genital chlamydial infections.

    abstract:BACKGROUND/OBJECTIVES:The polymer conjugate enhanced enzyme immunoassay (IDEIA) and Cobas Amplicor polymerase chain reaction Chlamydia trachomatis (CT) (Amplicor PCR) are two commonly used assays for the diagnosis of CT infection. The performance of these assays was compared for the diagnosis of genital CT infection am...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章

    doi:10.1136/sti.2005.015362

    authors: Jalal H,Stephen H,Al-Suwaine A,Sonnex C,Carne C

    更新日期:2006-02-01 00:00:00

  • Shared care in the management of genital Chlamydia trachomatis infection in primary care.

    abstract:OBJECTIVES:To investigate the impact of a health adviser in genitourinary medicine as a training and support resource on the management of Chlamydia trachomatis in a large inner city health centre. METHODS:A large, inner city health centre was selected at random for the intervention, with another selected as control. ...

    journal_title:Sexually transmitted infections

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1136/sti.79.5.369

    authors: Armstrong B,Kinn S,Scoular A,Wilson P

    更新日期:2003-10-01 00:00:00

  • Sexually transmitted diseases in sexually abused children: medical and legal implications.

    abstract::Sexually transmitted diseases (STDs) may be transmitted during sexual assault. In children, the isolation of a sexually transmitted organism may be the first indication that abuse has occurred. Although the presence of a sexually transmissible agent from a child beyond the neonatal period is suggestive of sexual abuse...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章,评审

    doi:10.1136/sti.74.3.167

    authors: Hammerschlag MR

    更新日期:1998-06-01 00:00:00

  • APOE genotype is associated with oral herpetic lesions but not genital or oral herpes simplex virus shedding.

    abstract:BACKGROUND:Apolipoprotein E is polymorphic in the human population. APOE4 has previously been reported to correlate with symptomatic oral and genital herpes disease. METHODS:APOE was genotyped in 182 subjects with herpes simplex virus (HSV) 2 and in 62 subjects with HSV-1, including 44 subjects with both viral types f...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章,多中心研究

    doi:10.1136/sti.2009.039735

    authors: Koelle DM,Magaret A,Warren T,Schellenberg GD,Wald A

    更新日期:2010-06-01 00:00:00

  • Challenges and emerging opportunities for the HIV prevention, treatment and care cascade in men who have sex with men in Asia Pacific.

    abstract::In Asia Pacific, most countries have expanded HIV treatment guidelines to include all those with HIV infection and adopted antiretroviral treatment for prevention (TFP) as a blanket strategy for HIV control. Although the overall epidemic development associated with this focus is positive, the HIV epidemic in men who h...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章,评审

    doi:10.1136/sextrans-2016-052669

    authors: van Griensven F,Guadamuz TE,de Lind van Wijngaarden JW,Phanuphak N,Solomon SS,Lo YR

    更新日期:2017-08-01 00:00:00

  • Seroadaptive behaviours among men who have sex with men in San Francisco: the situation in 2008.

    abstract:OBJECTIVES:To assess changes in seroadaptive behaviours among men who have sex with men (MSM) in San Francisco over the past 4 years. METHODS:461 MSM were recruited in 2008 as the second wave of the US National HIV Behavioural Surveillance (NHBS) survey in San Francisco. Participants were classified into patterns of s...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章

    doi:10.1136/sti.2010.042986

    authors: Snowden JM,Raymond HF,McFarland W

    更新日期:2011-03-01 00:00:00

  • Unique manifestations and risk factors of Jarisch-Herxheimer reaction during treatment of child congenital syphilis.

    abstract:OBJECTIVES:The objective of this retrospective study was to summarise the clinical manifestations of, and to analyse the incidence and risk factors of, Jarisch-Herxheimer reaction (JHR) during the treatment of children with symptomatic congenital syphilis. METHODS:Clinical data of 60 children with clinically and labor...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章

    doi:10.1136/sextrans-2016-053083

    authors: Wang C,He S,Yang H,Liu Y,Zhao Y,Pang L

    更新日期:2018-12-01 00:00:00

  • Prevalence and associations of recent physical intimate partner violence among women attending an Australian sexual health clinic.

    abstract:BACKGROUND:The Sydney Sexual Health Centre in Australia uses a proforma tool to screen all new female clients for recent physical intimate partner violence (IPV). This study describes the prevalence and associations of recent physical IPV among women attending a sexual health clinic. METHOD:The clinic database was use...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章

    doi:10.1136/sti.2010.043109

    authors: Lockart I,Ryder N,McNulty AM

    更新日期:2011-03-01 00:00:00

  • Using mathematical modelling to estimate the impact of periodic presumptive treatment on the transmission of sexually transmitted infections and HIV among female sex workers.

    abstract:BACKGROUND:In settings with poor sexually transmitted infection (STI) control in high-risk groups, periodic presumptive treatment (PPT) can quickly reduce the prevalence of genital ulcers, Neisseria gonorrhoeae (NG) and Chlamydia trachomatis (CT). However, few studies have assessed the impact on HIV. Mathematical model...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章,多中心研究

    doi:10.1136/sti.2008.034678

    authors: Vickerman P,Ndowa F,O'Farrell N,Steen R,Alary M,Delany-Moretlwe S

    更新日期:2010-06-01 00:00:00

  • Spontaneous clearance of urogenital, anorectal and oropharyngeal Chlamydia trachomatis and Neisseria gonorrhoeae in women, MSM and heterosexual men visiting the STI clinic: a prospective cohort study.

    abstract:OBJECTIVE:Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) infections can clear without treatment. Despite high prevalence of anorectal infections in men who have sex with men (MSM) and women, studies on anorectal clearance are scarce. Moreover it is unknown whether bacterial load affects urogenital/anorectal ...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章

    doi:10.1136/sextrans-2018-053825

    authors: van Liere GAFS,Hoebe CJPA,Dirks JA,Wolffs PF,Dukers-Muijrers NHTM

    更新日期:2019-11-01 00:00:00

  • Impact of HIV on adult (15-54) mortality in London: 1979-96.

    abstract:OBJECTIVE:To describe the impact of HIV on mortality in men and women aged 15-54 in London. DESIGN:Combination of routine mortality statistics with reports of AIDS deaths adjusted for underreporting and change in address from time of report to time of death. Calculation of standardised mortality ratios (SMRs) for male...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章

    doi:10.1136/sti.75.6.385

    authors: Hickman M,Bardsley M,De Angelis D,Ward H

    更新日期:1999-12-01 00:00:00

  • Discordance of HIV and HSV-2 biomarkers and self-reported sexual behaviour among orphan adolescents in Western Kenya.

    abstract:BACKGROUND:This paper examines the discordance between biological data of HIV and herpes simplex virus type 2 (HSV-2) infections and self-reported questionnaire responses among orphan adolescents in Western Kenya. METHODS:In 2011, 837 orphan adolescents from 26 primary schools were enrolled in an HIV prevention trial....

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章,多中心研究

    doi:10.1136/sextrans-2014-051720

    authors: Cho H,Luseno W,Halpern C,Zhang L,Mbai I,Milimo B,Hallfors DD

    更新日期:2015-06-01 00:00:00

  • Changes in high-risk sexual behaviour among Estonian adults between 1996 and 2006.

    abstract:OBJECTIVE:To describe and compare sexual behaviour patterns in 1996 (before the explosion of the HIV epidemic in 2000) and 2006, and the correlates of high-risk sexual behaviour in Estonia. METHODS:Data on selected sexual behaviour characteristics were obtained by interviewing a probability sample of the adult populat...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章

    doi:10.1136/sextrans-2012-050506

    authors: Liivlaid H,Uusküla A

    更新日期:2013-03-01 00:00:00

  • Human papillomavirus (HPV) vaccination and oropharyngeal HPV in ethnically diverse, sexually active adolescents: community-based cross-sectional study.

    abstract:OBJECTIVES:Oropharyngeal squamous cell carcinoma is the most common human papillomavirus (HPV)-associated cancer in the UK, but little is known about the prevalence of oropharyngeal HPV in sexually active teenagers. We investigated reported HPV vaccination coverage (in females) and prevalence of oropharyngeal HPV in se...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章

    doi:10.1136/sextrans-2020-054428

    authors: Kerry-Barnard S,Beddows S,Reid F,Beckley-Hoelscher N,Soldan K,Panwar K,Seran C,Fleming C,Lesniewska A,Planche T,Williamson J,Hay P,Oakeshott P

    更新日期:2020-09-03 00:00:00

  • Syndromic approach to STD case management: where do we go from here?

    abstract::In the absence of aetiological tests for the diagnosis of individual sexually transmitted diseases (STD), the syndromic approach has been developed as an effective and appropriate case management strategy. Algorithms provide guidance to healthcare workers and ensure standardised approaches to case management. The synd...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章

    doi:

    authors: van Dam CJ,Becker KM,Ndowa F,Islam MQ

    更新日期:1998-06-01 00:00:00

  • Human papillomavirus infection in female sex workers in Lima, Peru.

    abstract:OBJECTIVES:To determine the prevalence and risk factors for human papillomavirus (HPV) infection in female sex workers (FSW) in Lima, Peru. METHODS:Cross-sectional study of 87 FSW. Information regarding demographics, sex work practices, and genital and blood specimens was collected. RESULTS:Forty-four (50.6%) of 87 F...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章

    doi:10.1136/sti.2010.043315

    authors: Montano SM,Hsieh EJ,Calderón M,Ton TG,Quijano E,Solari V,Zunt JR

    更新日期:2011-02-01 00:00:00

  • Contribution of sexual practices (other than anal sex) to bacterial sexually transmitted infection transmission in men who have sex with men: a cross-sectional analysis using electronic health records.

    abstract:OBJECTIVE:We quantified the proportion of cases and risk of primary syphilis (PS), urethral chlamydia (UCT) and urethral gonorrhoea (UGC) attributable to sexual practices other than anal sex. METHODS:In this cross-sectional study, electronic records for men who have sex with men (MSM) who attended the Melbourne Sexual...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章

    doi:10.1136/sextrans-2013-051103

    authors: Nash JL,Hocking JS,Read TR,Chen MY,Bradshaw CS,Forcey DS,Fairley CK

    更新日期:2014-02-01 00:00:00

  • Syndromic management of sexually transmitted diseases at primary care level, Mozambique.

    abstract:OBJECTIVE:To assess STD management in primary healthcare facilities where STD clinics and syndromic management guidelines had been introduced. METHODS:In 26 health facilities in selected sites, we observed management of all STD patients presenting in the adult general or STD clinic. We assessed the referral system by ...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章

    doi:10.1136/sti.78.1.e2

    authors: Mbofana FS,Brito FJ,Saifodine A,Cliff JL

    更新日期:2002-02-01 00:00:00

  • Assessment of a real-time PCR test to diagnose syphilis from diverse biological samples.

    abstract:OBJECTIVES:To investigate the contribution of a real-time PCR assay for the detection of Treponema pallidum in various biological specimens with the secondary objective of comparing its value according to HIV status. METHODS:Prospective cohort of incident syphilis cases from three Swiss hospitals (Geneva and Bern Univ...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章,多中心研究

    doi:10.1136/sti.2008.034314

    authors: Gayet-Ageron A,Ninet B,Toutous-Trellu L,Lautenschlager S,Furrer H,Piguet V,Schrenzel J,Hirschel B

    更新日期:2009-08-01 00:00:00