Opportunities to Improve Antibiotic Appropriateness in U.S. ICUs: A Multicenter Evaluation.

abstract：BACKGROUND:Prevalence and causes of sex-based differences in morbidity and mortality secondary to cardiovascular disease remain controversial. Cardiac troponin I (cTnI) is a sensitive and specific marker for myocardial injury. Serial cTnI measurements have been used to identify perioperative myocardial cell injury. OB...

journal_title：Critical care medicine

authors： Schwarzenberger JC,Sun LS,Pesce MA,Heyer EJ,Delphin E,Almeida GM,Wood M

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND:Acute lung injury (ALI) and its more severe form, acute respiratory distress syndrome (ARDS), are devastating disorders of overwhelming pulmonary inflammation and hypoxemia, resulting in high morbidity and mortality. AIM:To provide the clinician with a summary of the literature on the epidemiology, diagnosi...

journal_title：Critical care medicine

authors： Randolph AG

更新日期：2009-08-01 00:00:00

abstract：OBJECTIVES:Despite the common occurrence of brain injury in patients undergoing extracorporeal membrane oxygenation, it is unclear which cannulation method carries a higher risk of brain injury. We compared the prevalence of brain injury between patients undergoing venoarterial and venovenous extracorporeal membrane ox...

journal_title：Critical care medicine

authors： Shoskes A,Migdady I,Rice C,Hassett C,Deshpande A,Price C,Hernandez AV,Cho SM

更新日期：2020-12-01 00:00:00

abstract：:A total of 2711 pulmonary artery wedge pressure (WP) measurement attempts were made prospectively from WP recordings in 44 (30 men) critically ill patients, using 77 flow-directed catheters. Of these, 322 (12%) failed to yield a WP measurement, and 521 (18%) were associated with technical problems. One half of these t...

journal_title：Critical care medicine

authors： Morris AH,Chapman RH,Gardner RM

更新日期：1984-03-01 00:00:00

abstract：OBJECTIVE:To evaluate the safety and diagnostic yield of transbronchial biopsy performed in mechanically ventilated patients. DESIGN:Retrospective, cohort analysis. SETTING:A university-affiliated teaching hospital. PATIENTS:Seventy-one consecutive, mechanically ventilated patients requiring lung tissue examination....

journal_title：Critical care medicine

authors： O'Brien JD,Ettinger NA,Shevlin D,Kollef MH

更新日期：1997-03-01 00:00:00

abstract：OBJECTIVE:To evaluate the potential clinical, metabolic, and economic advantages of enteral nutrition over total parenteral nutrition. DESIGN:Prospective, randomized clinical trial. SETTING:Department of surgery in a university hospital. PATIENTS:Two hundred and fifty-seven patients with cancer of the stomach (n = 1...

journal_title：Critical care medicine

authors： Braga M,Gianotti L,Gentilini O,Parisi V,Salis C,Di Carlo V

更新日期：2001-02-01 00:00:00

abstract：OBJECTIVES:To synthesize the literature describing interventions to improve hand hygiene in ICUs, to evaluate the quality of the extant research, and to outline the type, and efficacy, of interventions described. DATA SOURCES:Systematic searches were conducted in November 2016 using five electronic databases: Medline,...

journal_title：Critical care medicine

authors： Lydon S,Power M,McSharry J,Byrne M,Madden C,Squires JE,O'Connor P

更新日期：2017-11-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to investigate whether hyperglycemia enhances the systemic inflammatory response and oxidative stress induced by endotoxin. DESIGN:Laboratory investigation. SETTING:University medical school. SUBJECTS:Forty-one male Sprague-Dawley rats. INTERVENTIONS:A hyperglycemic condition was...

journal_title：Critical care medicine

authors： Ling PR,Smith RJ,Bistrian BR

更新日期：2005-05-01 00:00:00

abstract：OBJECTIVE:To assess the coping strategies used by family decision makers of adult critical care patients during and after the critical care experience and the relationship of coping strategies to posttraumatic stress symptoms experienced 60 days after hospitalization. DESIGN:A single-group descriptive longitudinal cor...

journal_title：Critical care medicine

authors： Petrinec AB,Mazanec PM,Burant CJ,Hoffer A,Daly BJ

更新日期：2015-06-01 00:00:00

abstract：:Sixty-four (48%) of 133 children with hematologic malignancy who were admitted to three pediatric ICUs died. Children who required management because of airway obstruction or after general anesthesia had the best outlook (mortality rate of 7% or less); those children who required major circulatory support or mechanica...

journal_title：Critical care medicine

authors： Butt W,Barker G,Walker C,Gillis J,Kilham H,Stevens M

更新日期：1988-08-01 00:00:00

abstract：OBJECTIVE:To determine recent trends in severe sepsis-related rates of hospitalization, mortality, and hospital case fatality in a large geographic area and to determine the impact of age, race, and gender on these outcomes. DESIGN:Trend analysis for the period of 1995 to 2002. SETTING:Acute care hospitals in New Jer...

journal_title：Critical care medicine

authors： Dombrovskiy VY,Martin AA,Sunderram J,Paz HL

更新日期：2005-11-01 00:00:00

abstract：OBJECTIVES:To address the association between the 2003 heat wave in Paris (France) and the occurrence of out-of-hospital cardiac arrest. DESIGN:: An analysis of the interventions of the medical mobile intensive care units of the City of Paris for out-of-hospital cardiac arrest and prehospital myocardial infarctions, w...

journal_title：Critical care medicine

authors： Empana JP,Sauval P,Ducimetiere P,Tafflet M,Carli P,Jouven X

更新日期：2009-12-01 00:00:00

abstract：:Hypersensitivity reactions are defined as immunologically based adverse reactions to chemicals or medicinal agents. These reactions are common in the intensive care unit and can present as a simple, mildly symptomatic rash or as life-threatening anaphylactic reactions. Hypersensitivity reactions have traditionally bee...

journal_title：Critical care medicine

authors： Kanji S,Chant C

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVE:To test the hypothesis that nebulized nitroprusside and inhaled nitric oxide would not differ in producing selective pulmonary vasodilation during hypoxia-induced pulmonary hypertension in piglets. SETTING:University laboratory. SUBJECTS:Five piglets. INTERVENTIONS:Piglets (n = 5) were anesthetized and ins...

journal_title：Critical care medicine

authors： Schreiber MD,Dixit R,Rudinsky B,Hipps R,Morgan SE,Keith RRT A,Meadow W

更新日期：2002-11-01 00:00:00

abstract：OBJECTIVE:This report will describe the preparations for and the provision of care of two patients with Ebola virus disease in the biocontainment unit at the University of Nebraska Medical Center. DATA SOURCES:Patient medical records. STUDY SELECTION:Not applicable. DATA EXTRACTION:Not applicable. DATA SYNTHESIS:No...

journal_title：Critical care medicine

authors： Johnson DW,Sullivan JN,Piquette CA,Hewlett AL,Bailey KL,Smith PW,Kalil AC,Lisco SJ

更新日期：2015-06-01 00:00:00

abstract：OBJECTIVES:We aimed to implement our Smart Use of Antibiotics Program to ensure the proper use of antimicrobials, improve patient care and outcomes, and reduce the risks of adverse effects and antimicrobial resistance. DESIGN:We compared the time periods before (baseline) and after (intervention) the implementation of...

journal_title：Critical care medicine

authors： Lu C,Liu Q,Yuan H,Wang L

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVE:To assess the effect of a helium-oxygen mixture on intubation rate and clinical outcomes during noninvasive ventilation in acute exacerbation of chronic obstructive pulmonary disease. DESIGN:Multicenter, prospective, randomized, controlled trial. SETTING:Seven intensive care units. PATIENTS:A total of 204 ...

journal_title：Critical care medicine

authors： Maggiore SM,Richard JC,Abroug F,Diehl JL,Antonelli M,Sauder P,Mancebo J,Ferrer M,Lellouche F,Lecourt L,Beduneau G,Brochard L

更新日期：2010-01-01 00:00:00

abstract：:The current investigation describes the morphological and pathophysiological effects of stroma-free hemoglobin solution (SFH) on the liver and kidney. One h after a 75% blood volume exchange in animals receiving 7% SFH, hepatic morphology was normal. Animals whose blood was similarly exchanged with 7% albumin demonstr...

journal_title：Critical care medicine

authors： Friedman HI,DeVenuto F

更新日期：1982-04-01 00:00:00

abstract：OBJECTIVE:To evaluate the relationship between the acute inflammatory response after surgical trauma and changes in hepatic cytochrome P450 3A4 activity, compare changes in cytochrome P450 3A4 activity after procedures with varying degrees of surgical stress, and to explore the time course of any potential drug-cytokin...

journal_title：Critical care medicine

authors： Haas CE,Kaufman DC,Jones CE,Burstein AH,Reiss W

更新日期：2003-05-01 00:00:00

abstract：:A case of rabies was treated with intensive medical support. This led to a prolongation of life to 25 days. The neurologic progression of the disease was monitored clinically and with serial EEG. This prolonged course enabled us to witness and manage a wide variety of unusual complications including the adult respirat...

journal_title：Critical care medicine

authors： Udwadia ZF,Udwadia FE,Katrak SM,Dastur DK,Sekhar M,Lall A,Kumta A,Sane B

更新日期：1989-08-01 00:00:00

abstract：BACKGROUND:Septic shock represents the major cause of infection-associated mortality in the intensive care unit. The possibility that combination antibiotic therapy of bacterial septic shock improves outcome is controversial. Current guidelines do not recommend combination therapy except for the express purpose of broa...

journal_title：Critical care medicine

authors： Kumar A,Zarychanski R,Light B,Parrillo J,Maki D,Simon D,Laporta D,Lapinsky S,Ellis P,Mirzanejad Y,Martinka G,Keenan S,Wood G,Arabi Y,Feinstein D,Kumar A,Dodek P,Kravetsky L,Doucette S,Cooperative Antimicrobial Thera

更新日期：2010-09-01 00:00:00

abstract：OBJECTIVE:The efficacy of noninvasive mechanical ventilation (NIMV) in improving breathing pattern and arterial blood gases (ABG) in hypercapnic patients has been well documented; however, little attention has been given to the choice of the interface and the ventilatory mode. We evaluated the effects of three types of...

journal_title：Critical care medicine

authors： Navalesi P,Fanfulla F,Frigerio P,Gregoretti C,Nava S

更新日期：2000-06-01 00:00:00

abstract：OBJECTIVE:Phenylephrine is often used for management of cerebral perfusion pressure after traumatic brain injury, but can have undesirable actions. Few studies have evaluated alternatives. The hypothesis was that arginine vasopressin was as effective as phenylephrine for maintaining tissue oxygenation during cerebral p...

journal_title：Critical care medicine

authors： Dudkiewicz M,Proctor KG

更新日期：2008-09-01 00:00:00

abstract：OBJECTIVE:Use of antibiotics in critically ill patients may increase the risk of invasive Candida infection. The objective of this study was to determine whether increased exposure to antibiotics is associated with increased prevalence of invasive Candida infection. DESIGN:Substudy using data from a randomized control...

journal_title：Critical care medicine

authors： Jensen JU,Hein L,Lundgren B,Bestle MH,Mohr T,Andersen MH,Løken J,Tousi H,Søe-Jensen P,Lauritsen AØ,Strange D,Petersen JA,Thormar K,Larsen KM,Drenck NE,Helweg-Larsen J,Johansen ME,Reinholdt K,Møller JK,Olesen B,Are

更新日期：2015-03-01 00:00:00

abstract：OBJECTIVES:To determine the outcome of oxygen consumption (VO2) and energy expenditure after cessation of sedation in severe head-injured patients and to assess its usefulness as a predictor of neurologic severity. DESIGN:Prospective, descriptive study. SETTING:Neurosurgical intensive care unit (ICU) in a university ...

journal_title：Critical care medicine

authors： Bruder N,Lassegue D,Pelissier D,Graziani N,François G

更新日期：1994-07-01 00:00:00

abstract：:Previously, we determined that a colloid concentration of about 3% was optimal for resuscitation of lethal ischemic intestinal shock model in rats. Maximal volumes of lactated Ringer's solution (RL) alone only expanded plasma volume (PV) to 80% of preshock level, while increasing volumes of 3% albumin (ALB) in RL line...

journal_title：Critical care medicine

authors： Dawidson IJ,Willms C,Sandor ZF,Armstrong J,Wilson L

更新日期：1990-01-01 00:00:00

abstract：OBJECTIVES:To describe the incident fracture rate in survivors of critical illness and to compare fracture risk with population-matched control subjects. DESIGN:Retrospective longitudinal case-cohort study. SETTING:A tertiary adult intensive care unit in Australia. PATIENTS:All patients ventilated admitted to intens...

journal_title：Critical care medicine

authors： Orford NR,Saunders K,Merriman E,Henry M,Pasco J,Stow P,Kotowicz M

更新日期：2011-06-01 00:00:00

abstract：OBJECTIVE:The beneficial effects of hypertonic saline on neuronal survival and on cerebral blood flow have been shown in several animal models of global and focal brain ischemia. Because of the potential benefits of hypertonic solutions, it is hypothesized that hydroxyethyl starch enhances cerebral blood flow and impro...

journal_title：Critical care medicine

authors： Noppens RR,Kelm RF,Lindemann R,Engelhard K,Werner C,Kempski O

更新日期：2012-07-01 00:00:00

abstract：:During the treatment of 26 shocked patients, measurements were made of the central blood to peripheral skin temperature gradient. No significant correlation was found between this gradient and cardiac index (CI), or systemic vascular resistance (SVR) or its index (SVRI). There was no significant correlation between th...

journal_title：Critical care medicine

authors： Woods I,Wilkins RG,Edwards JD,Martin PD,Faragher EB

更新日期：1987-09-01 00:00:00

abstract：OBJECTIVE:To investigate glycemic dynamics and its relation with mortality in critically ill patients. We searched for differences in complexity of the glycemic profile between survivors and nonsurvivors in patients admitted to a multidisciplinary intensive care unit. DESIGN:Prospective, observational study, convenien...

journal_title：Critical care medicine

authors： Lundelin K,Vigil L,Bua S,Gomez-Mestre I,Honrubia T,Varela M

更新日期：2010-03-01 00:00:00