Energy expenditure and withdrawal of sedation in severe head-injured patients.

abstract：OBJECTIVES:A cuffed tracheostomy tube facilitates prolonged mechanical ventilation and weaning but usually leads to prolonged voicelessness, which can be one of the most negative experiences of hospitalization. No randomized trials have examined the effects of targeted early communication intervention for the restorati...

journal_title：Critical care medicine

authors： Freeman-Sanderson AL,Togher L,Elkins MR,Phipps PR

更新日期：2016-06-01 00:00:00

abstract：:Because determining cardiac output is difficult in premature infants, little is known about the hemodynamic effects of PEEP in this age group. We used pulsed-wave Doppler echocardiography to assess the hemodynamic effects of PEEP increments in ten premature infants with respiratory distress syndrome. At a PEEP of 4 cm...

journal_title：Critical care medicine

authors： Hausdorf G,Hellwege HH

更新日期：1987-07-01 00:00:00

abstract：OBJECTIVE:Several studies report calcium mishandling, sarcomere disarray, and caspase activation during heart failure. Although active caspases have been shown to cleave myofibrillar proteins, little is known regarding their effects on calcium handling proteins. Therefore, we aimed to explore how endotoxin-induced casp...

journal_title：Critical care medicine

authors： Neviere R,Hassoun SM,Decoster B,Bouazza Y,Montaigne D,Maréchal X,Marciniak C,Marchetti P,Lancel S

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVE:To test the reliability and validity of a modified moral distress tool, originally developed for the nursing profession, on respiratory care practitioners. To describe the relationship between moral distress, career dissatisfaction, and job turnover in respiratory care. DESIGN:A 28-question survey was develo...

journal_title：Critical care medicine

authors： Schwenzer KJ,Wang L

更新日期：2006-12-01 00:00:00

abstract：OBJECTIVE:To evaluate carbamezapine (CBZ) for neuritic pain relief in Guillain-Barré syndrome (GBS) patients in the intensive care unit (ICU). DESIGN:Prospective, double-blind, randomly allocated cross-over study days. SETTING:ICU in a tertiary care university hospital. PARTICIPANTS:Twelve consecutive, conscious adu...

journal_title：Critical care medicine

authors： Tripathi M,Kaushik S

更新日期：2000-03-01 00:00:00

abstract：OBJECTIVE:To evaluate the physiology and pharmacokinetics of a novel hemoglobin-based oxygen carrier of bovine origin. DESIGN:Randomized, single-blind, placebo-controlled, dose-escalation study. SETTING:The Upjohn Research Clinics (Kalamazoo, MI). SUBJECTS:Normal healthy adult men between the ages of 18 and 45 yrs. ...

journal_title：Critical care medicine

authors： Hughes GS Jr,Antal EJ,Locker PK,Francom SF,Adams WJ,Jacobs EE Jr

更新日期：1996-05-01 00:00:00

abstract：:Subcutaneous, transcutaneous, and conjunctival oxygen tensions (PscO2, PtcO2, and PcjO2, respectively) were measured in anesthetized dogs subjected sequentially to normoxia, hyperoxia, and hypoxia. Intravascular pressure, hemodynamic and oxygen transport variables were measured simultaneously. PtcO2 and PcjO2 closely ...

journal_title：Critical care medicine

authors： Gottrup F,Gellett S,Kirkegaard L,Hansen ES,Johannsen G

更新日期：1988-12-01 00:00:00

abstract：OBJECTIVE:To examine the association between the performance of a tracheostomy and intensive care unit and postintensive care unit mortality, controlling for treatment selection bias and confounding variables. DESIGN:Prospective, observational, cohort study. SETTING:Twelve French medical or surgical intensive care un...

journal_title：Critical care medicine

authors： Clec'h C,Alberti C,Vincent F,Garrouste-Orgeas M,de Lassence A,Toledano D,Azoulay E,Adrie C,Jamali S,Zaccaria I,Cohen Y,Timsit JF

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVES:To assess the variability in short-term sepsis mortality by hospital among Centers for Medicare and Medicaid Services beneficiaries in the United States during 2013-2014. DESIGN:A retrospective cohort design. SETTING:Hospitalizations from 3,068 acute care hospitals that participated in the Centers for Medi...

journal_title：Critical care medicine

authors： Hatfield KM,Dantes RB,Baggs J,Sapiano MRP,Fiore AE,Jernigan JA,Epstein L

更新日期：2018-11-01 00:00:00

abstract：OBJECTIVE:To investigate the effect of norepinephrine on static (right atrial pressure, pulmonary artery occlusion pressure ) and dynamic (pulse pressure variation and arterial systolic pressure variation) preload indicators in experimental hemorrhagic shock. DESIGN:Prospective controlled experimental study. SETTING:...

journal_title：Critical care medicine

authors： Nouira S,Elatrous S,Dimassi S,Besbes L,Boukef R,Mohamed B,Abroug F

更新日期：2005-10-01 00:00:00

abstract：:Intravenous dobutamine was used in ten patients requiring aggressive therapy for massive pulmonary embolism with circulatory failure. Except in one patient who rapidly died, a 30-min dobutamine infusion (8.3 +/- 2.7 micrograms/kg . min) increased both cardiac index (from 1.7 +/- 0.4 to 2.3 +/- 0.6 L/min . m2, p less t...

journal_title：Critical care medicine

authors： Jardin F,Genevray B,Brun-Ney D,Margairaz A

更新日期：1985-12-01 00:00:00

abstract：OBJECTIVE:Transarterial chemoembolization is a widely used therapy for the treatment of hepatocellular carcinoma. A rare adverse event is acute respiratory distress syndrome from pulmonary embolization of Lipiodol, an iodinated oil commonly used during the procedure. The objective of this report is to describe an atypi...

journal_title：Critical care medicine

authors： Taupin D,Mukherjee V,Nathavitharana R,Green DA,Fridman D

更新日期：2014-06-01 00:00:00

abstract：OBJECTIVES:To compare the incidence of withdrawal or withholding of life support (WD/WHLS), and to identify similarities and differences in the process of the withdrawal of life support (WDLS) between teaching and community hospitals' intensive care units (ICUs). DESIGN:Prospective cohort study, with some data obtaine...

journal_title：Critical care medicine

authors： Keenan SP,Busche KD,Chen LM,Esmail R,Inman KJ,Sibbald WJ

更新日期：1998-02-01 00:00:00

abstract：:Reproducibility of thermal-dye extravascular lung water (EVLW) estimation by a lung water computer was studied by performing ten consecutive measurements in 45 critically ill patients. EVLW ranged over a wide spectrum from 187 to 1163 ml (2.4 to 18.6 ml/kg). The mean coefficient of variation of ten consecutive measure...

journal_title：Critical care medicine

authors： Laggner AN,Lenz K,Druml W,Kleinberger G

更新日期：1987-06-01 00:00:00

abstract：OBJECTIVES:Radial artery applanation tonometry allows completely noninvasive continuous cardiac output estimation. The aim of the present study was to compare cardiac output measurements obtained with applanation tonometry (AT-CO) using the T-Line system (Tensys Medical, San Diego, CA) with cardiac output measured by i...

journal_title：Critical care medicine

authors： Wagner JY,Sarwari H,Schön G,Kubik M,Kluge S,Reichenspurner H,Reuter DA,Saugel B

更新日期：2015-07-01 00:00:00

abstract：:This report is intended to familiarize the reader with the current legislation concerning state definitions of death, the pertinent judicial decisions concerning termination of life support and the current status of medical/ethical committees. However, it is of paramount importance to all health care personnel to beco...

journal_title：Critical care medicine

authors： Wallace-Barnhill G,Roth MD,Briggs BA,Bastron DR,Barrocas A

更新日期：1982-01-01 00:00:00

abstract：OBJECTIVES:Studies have shown contradicting results on the association of nursing workload and mortality. Most of these studies expressed workload as patients per nurse ratios; however, this does not take into account that some patients require more nursing time than others. Nursing time can be quantified by tools like...

journal_title：Critical care medicine

authors： Margadant C,Wortel S,Hoogendoorn M,Bosman R,Spijkstra JJ,Brinkman S,de Keizer N

更新日期：2020-01-01 00:00:00

abstract：:To understand better the incidence and meaning of hyperamylasemia in the intensive care setting, cellulose acetate membrane electrophoresis was used to measure the isoenzymes of serum amylase in 192 patients with a variety of critical illnesses. Seventy of these patients had elevated serum amylase levels, but none had...

journal_title：Critical care medicine

authors： Weaver DW,Busuito MJ,Bouwman DL,Wilson RF

更新日期：1985-07-01 00:00:00

abstract：OBJECTIVES:To determine if vecuronium doses individualized by peripheral nerve stimulation are lower than those doses chosen by standard clinical techniques; and to determine whether patients monitored by peripheral nerve stimulation exhibit shorter recovery times and less prolonged neuromuscular blockade after discont...

journal_title：Critical care medicine

authors： Rudis MI,Sikora CA,Angus E,Peterson E,Popovich J Jr,Hyzy R,Zarowitz BJ

更新日期：1997-04-01 00:00:00

abstract：OBJECTIVE:To examine the role of platelets, fibrin, and adhesion molecules in mediating neutrophil-endothelial cell interactions in septic shock. DESIGN:Controlled experiments using phase contrast microscopy to examine neutrophil, platelet, and endothelial cell interactions in flowing cell suspensions under simulated ...

journal_title：Critical care medicine

authors： Kirschenbaum LA,McKevitt D,Rullan M,Reisbeck B,Fujii T,Astiz ME

更新日期：2004-09-01 00:00:00

abstract：:Clonidine may be a source of serious toxicity when ingested by toddlers. We describe 11 cases of clonidine ingestion by toddlers (mean dose 0.15 mg/kg; range 0.01 to 0.57). The source of the clonidine was a grand-parent in six of 11 cases. Symptoms included altered level of consciousness (n = 11), miosis (n = 5), brad...

journal_title：Critical care medicine

authors： Fiser DH,Moss MM,Walker W

更新日期：1990-10-01 00:00:00

abstract：OBJECTIVE:Review data obtained from high-frequency oscillatory ventilation (HFOV) and mechanical test lung models with respect to delivered tidal volume, distal pressure transmission, endotracheal tube cuff leaks, and simulated clinical conditions. DESIGN:Review of selected studies from PubMed, published abstracts, an...

journal_title：Critical care medicine

authors： Van de Kieft M,Dorsey D,Morison D,Bravo L,Venticinque S,Derdak S

更新日期：2005-03-01 00:00:00

abstract：:We analyzed 35 samples of fresh frozen plasma (FFP), finding mean concentrations of 535 mg/dl glucose, 172 mEq/L sodium, 73 mEq/L chloride, 3.5 mEq/L potassium, 15 mEq/L bicarbonate, and 5.5 g/dl protein with 60% albumin. Thus, FFP is a hyperosmolal, hyperglycemic, hypernatremic, and hypochloremic solution which may b...

journal_title：Critical care medicine

authors： Ewalenko P,Deloof T,Peeters J

更新日期：1986-02-01 00:00:00

abstract：:We studied prospectively 40 critically ill neurosurgical patients who required prolonged mechanical ventilation to determine the current incidence of stress-related gastroduodenal erosions and ulcers, and to assess endoscopically the efficacy of acid-reducing prophylactic treatment. Nineteen patients were randomized t...

journal_title：Critical care medicine

authors： Reusser P,Gyr K,Scheidegger D,Buchmann B,Buser M,Zimmerli W

更新日期：1990-03-01 00:00:00

abstract：OBJECTIVE:We investigated whether serum levels of neuron-specific enolase (NSE) and S-100beta protein could be used to evaluate cerebral injury and to predict outcome in severe sepsis and severe septic shock. DESIGN:Prospective study. SETTING:University hospital. PATIENTS AND MEASUREMENTS:In 170 consecutively enroll...

journal_title：Critical care medicine

authors： Nguyen DN,Spapen H,Su F,Schiettecatte J,Shi L,Hachimi-Idrissi S,Huyghens L

更新日期：2006-07-01 00:00:00

abstract：OBJECTIVES:Prone-position ventilation (PPV) induces acute improvement in oxygenation in many patients with acute respiratory distress syndrome (ARDS), with some maintaining their oxygenation even after they were returned to the supine position, but it is unclear what clinical factors determine the sustained oxygenation...

journal_title：Critical care medicine

authors： Lee DL,Chiang HT,Lin SL,Ger LP,Kun MH,Huang YC

更新日期：2002-07-01 00:00:00

abstract：OBJECTIVE:To explore the hypothesis that beta-1 adrenoreceptor blockade may be protective through the attenuation of sympathetic hyperactivity and catecholaminergic inflammatory effects on cardiac and hepatic function. DESIGN:Prospective, randomized, controlled study. SETTING:Animal laboratory in a university medical...

journal_title：Critical care medicine

authors： Ackland GL,Yao ST,Rudiger A,Dyson A,Stidwill R,Poputnikov D,Singer M,Gourine AV

更新日期：2010-02-01 00:00:00

abstract：:In a series of 56 patients (24 uncomplicated postoperative and 32 septic patients), neopterin and elastase alpha 1 protease inhibitor complex (E-alpha 1 PI) plasma levels were measured daily. The clinical course of each patient was evaluated with the Multiple Organ Failure (MOF) score according to Goris. Neopterin cou...

journal_title：Critical care medicine

authors： Pacher R,Redl H,Frass M,Petzl DH,Schuster E,Woloszczuk W

更新日期：1989-03-01 00:00:00

abstract：OBJECTIVE:To determine whether a cellular phone would interfere with the operation of mechanical ventilators. DESIGN:Laboratory study. SETTING:University medical center. SUBJECTS:Fourteen mechanical ventilators. INTERVENTIONS:We evaluated change in operation and malfunction of the mechanical ventilators. MEASUREME...

journal_title：Critical care medicine

authors： Shaw CI,Kacmarek RM,Hampton RL,Riggi V,El Masry A,Cooper JB,Hurford WE

更新日期：2004-04-01 00:00:00

abstract：:The relationship between oxygen uptake (Vo2) and delivery (Do2) was examined in 64 patients immediately after cardiopulmonary bypass. In 44 patients with lactate levels below 2.5 mmol/L, Vo2 decreased proportionally when Do2 decreased below 300 ml/min X m2. At a Do2 over this level, Vo2 plateaued at 105 +/- 13 (SD) ml...

journal_title：Critical care medicine

authors： Komatsu T,Shibutani K,Okamoto K,Kumar V,Kubal K,Sanchala V,Lees DE

更新日期：1987-03-01 00:00:00