Abstract:
OBJECTIVE:To examine the role of cervicovaginal cytology in diagnoses and surveillance of the patients with endometrial carcinoma (EC). METHODS:Patients who underwent EC surgery that included a follow-up were reviewed retrospectively. The cohort was limited to the patients who had an available cervical cytology result within 12 months before the primary surgery took place. The glandular abnormalities were classified in the following subclassifications: "atypical glandular cells" (AGC)-not otherwise specified (NOS), AGC-favor neoplasia, endocervical AIS, and adenocarcinoma. RESULTS:A total of 411 patients were eligible for the study. The cervical cytology was found to be normal and recorded as negative for intraepithelial lesion or malignancy in 368 (89.5%) patients. In 43 (10.5%) patients, cervical cytology was interpreted as: AGC-NOS (n = 11), AGC-FN (n = 7), adenocarcinoma (n = 20), malignant epithelial tumor (n = 3), and squamous carcinoma (n = 2). During the follow-up, recurrence was observed in 53 (12.9%) patients. Among six isolated vaginal cuff recurrences, two of the cases presented with malignant cytology, and the additional four cases were suspected during clinical examination. Among women with recurrence (n = 53), there were malignant cytological findings in four of the patients. In the whole population (n = 411), there were four other abnormal cytological findings detected within the surveillance. These four cytology results were nonmalignant and no recurrence was identified. CONCLUSION:There is no significant clinical advantage of cervicovaginal cytology testing before diagnosis or during the surveillance of EC.
journal_name
Diagn Cytopatholjournal_title
Diagnostic cytopathologyauthors
Kilic D,Yetimalar MH,Bezircioglu I,Yigit Sdoi
10.1002/dc.24444subject
Has Abstractpub_date
2020-07-01 00:00:00pages
629-634issue
7eissn
8755-1039issn
1097-0339journal_volume
48pub_type
杂志文章abstract::Granulosa cell tumors (GCT) of the ovary are low grade tumor with a potential ability of late pelvic recurrences and distant metastases. However, there is sparse literature on the cytopathologic features of metastatic granulosa cell tumors (MGCT). Between 2000 and 2014, eight cases of MGCT were diagnosed by FNA. Clini...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.23535
更新日期:2016-12-01 00:00:00
abstract::Malignant pleural effusions due to prostatic carcinoma are rare. We examined the cytologic and clinical presentations of 14 malignant pleural effusions caused by prostate cancer. These cases represented 2.3% of all positive pleural effusions at our institution. All patients (n = 10) had high grade, high stage tumors, ...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
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abstract::Myoepithelial carcinoma is a rare locally aggressive malignant neoplasm of the salivary glands. The tumor is composed almost exclusively of tumor cells with myoepithelial differentiation and characterized by infiltrative growth and potential for distant metastasis. Tumor cells often display morphologic heterogeneity w...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章,评审
doi:10.1002/dc.21196
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abstract::The incidence of esophageal carcinoma continues to increase whilst its prognosis remains poor. The most dramatic reduction in mortality is likely to follow early diagnosis of the preinvasive precursor lesion, Barrett's esophagus (BE), coupled with treatment of dysplastic lesions. The major risk factor for BE is gastro...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章,评审
doi:10.1002/dc.24354
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abstract::The aim of this study were (1) To correlate koilocytosis with high risk HPV(HrHPV) DNA in urinary bladder carcinoma and (2) To compare detection of koilocytosis on tissue sections and urine cytology. Biopsy and cytologic specimens from 33 patients of urinary bladder carcinoma were analyzed. HPV DNA was detected by PCR...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.20978
更新日期:2009-03-01 00:00:00
abstract::Genital tract tuberculosis is usually secondary to an extragenital tubercular focus. Cervical tuberculosis, however, is rare accounting for up to 3% of all genital tract diseases. The diagnosis of tuberculosis is usually established on multiple cervical biopsies followed by bacteriological confirmation. There are only...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章,评审
doi:10.1002/dc.21082
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abstract::Adamantinoma of long bones is a rare, primary bone tumor of controversial histogenesis, usually arising in the anterior midshaft of the tibia. This slowly growing, radiolucent, expansile tumor eventually causes thinning or destruction of overlying cortical bone. Fine-needle aspiration biopsy (FNAB) is a rapid, safe, a...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.2840040116
更新日期:1988-03-01 00:00:00
abstract::Primary pulmonary Hodgkin's lymphoma (PPHL) is extremely rare. At an extranodal location such as the lung this lymphoma is likely to be confused with the more commonly occurring carcinomas at this site. We report the fine needle aspiration cytology (FNAC) findings of a PPHL in a 36-year-old male with a view to discuss...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.20872
更新日期:2008-09-01 00:00:00
abstract::Clear cell hepatocellular carcinoma (CCHCC) is an uncommon morphologic variant of HCC and rarely invades into the main bile ducts. Here we describe a case of CCHCC that was diagnosed by bile duct brushing cytology. Liquid-based preparation of brushing specimen showed clusters of atypical epithelial cells with abundant...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.23397
更新日期:2016-02-01 00:00:00
abstract::Over the past decade, core biopsy rapidly replaced fine needle aspiration (FNA) in evaluation of diseases of the female breast in many centers in the USA. The inability to diagnose invasive cancer by FNA, and the general feeling of unease in interpretation of cytologic specimens among pathologists who are not trained ...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.20987
更新日期:2009-02-01 00:00:00
abstract::A case of an immature teratoma of the ovary in the peritoneal fluid of a 10-yr-old girl who presented with a pelvic mass is presented and discussed. The ThinPrep preparation showed a few tight clusters of small tumor cells with a high nuclear/cytoplasmic ratio, round to oval nuclei with evenly distributed chromatin an...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.10034
更新日期:2001-12-01 00:00:00
abstract::Primary neuroendocrine carcinoma (carcinoid tumor) is among the rarest of middle-ear (ME) neoplasms, with only a rare case of metastatic disease having been reported. Fine-needle aspiration biopsy (FNAB) was performed in a 51-yr-old male with a two-decade history of multiple local recurrences from a right middle-ear n...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.2031
更新日期:2001-09-01 00:00:00
abstract::Serous tubal intraepithelial carcinoma (STIC) has attracted attention as a precursor lesion of high-grade serous carcinoma (HGSC) of the ovary. We report the rare case of a woman in whom adenocarcinoma cells were detected in cervical smears and demonstrated to be derived from STIC in the fimbria. The patient was a 48-...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.23957
更新日期:2018-11-01 00:00:00
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journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/(sici)1097-0339(199912)21:6<394::aid-dc5>3
更新日期:1999-12-01 00:00:00
abstract::Tuberculous and fungal infections are among the non-neoplastic lesions of the lung, in which fine-needle aspiration cytology (FNAC) has proven to be a useful technique in both immunocompromised and immunocompetent patients. The presence of polymicrobial infection in a renal transplant recipient is documented in the li...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.21198
更新日期:2010-04-01 00:00:00
abstract::Metastatic urothelial carcinoma (UC) to serous effusion (SE) is extremely rare and its cytomorphological features have only been described in case reports. In this study, we searched the pathology database at University of Michigan for SEs due to metastatic UC in the last 20 years. A total of 25 cases from 20 patients...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.22896
更新日期:2013-07-01 00:00:00
abstract::The cytologic findings in 13 cases of cervical adenocarcinoma in situ (mean age 33.9 yr) were compared with those in 9 cases of cervical invasive adenocarcinoma (mean age 45.7 yr). All diagnoses were confirmed by biopsy. The major differences found were that a necrotic background (66% invasive vs. 0% in situ) and macr...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.2840120206
更新日期:1995-03-01 00:00:00
abstract::Vaginal reconstruction has become an established method to restore sexual function in women who have undergone ultraradical surgery and/or irradiation for the treatment of gynecologic malignancies. Cytologic evaluation of the neovagina serves a major role in the detection of recurrent disease. The purpose of this retr...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.2840130106
更新日期:1995-07-01 00:00:00
abstract::The aim of this study is to compare micronucleus assay in buccal smear of breast carcinoma patients versus normal benign cases as control group. In this prospective study, we selected a total 32 patients of carcinoma of breast and 49 patients of benign breast lesions diagnosed in fine needle aspiration cytology (FNAC)...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.21589
更新日期:2012-08-01 00:00:00
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journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.24627
更新日期:2020-10-01 00:00:00
abstract::Pneumocystis carinii pneumonia (PCP) is a major infectious complication of immunodeficiency states, including the acquired immunodeficiency syndrome (AIDS). Bronchoalveolar lavage (BAL) is a safe and effective procedure for making this diagnosis. In addition to the characteristic organisms, both histologic and cytolog...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.2840040206
更新日期:1988-01-01 00:00:00
abstract::True thymic hyperplasia (TH) is an age-dependent increase in size and weight of the thymus gland, which by definition maintains a normal histologic architecture. TH can mimic other important diseases, including lymphofollicular hyperplasia, thymoma, lymphoma, and germ-cell tumors. Traditionally, separating these entit...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/1097-0339(200012)23:6<417::aid-dc12>3.0.co
更新日期:2000-12-01 00:00:00
abstract::Hepatic angiomyolipoma (HAML) is a rare mesenchymal neoplasm that belongs to the perivascular epithelioid tumor family. Though it is characteristically, a triphasic tumor composed of smooth muscle, blood vessels, and adipocytes, the smooth muscle cells are often epithelioid and can represent the near-entirety of the t...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.24688
更新日期:2020-12-29 00:00:00
abstract:BACKGROUND:The 2012 American Society for Colposcopy and Cervical Pathology Consensus Guidelines provide information for managing abnormal cervical cancer screening tests and cancer precursors. According to these guidelines for Pap smear diagnosis of Atypical squamous cells of undetermined significance, reflex high risk...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.24158
更新日期:2019-07-01 00:00:00
abstract::The limitation of cytologic still images is one of the reasons why telecytology has not met with widespread acceptance by the cytology community. Cytologic still image only displays a single depth of field, and this is a particularly acute problem in cytology where the specimen is often much thicker than a single micr...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.21078
更新日期:2009-10-01 00:00:00
abstract::Giant cell glioblastoma is a histological variant of glioblastoma that accounts for less than 1% of intracranial tumors and to 5% of glioblastoma. They occur at any age and are likely to affect the younger as well the older age group unlike the conventional glioblastoma multiforme (GBM). They are often located subcort...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章,评审
doi:10.1002/dc.21648
更新日期:2012-05-01 00:00:00
abstract::Hepatic leiomyosarcoma is a rare malignancy to involve the liver, occurring as a primary liver sarcoma in patients without an underlying medical disorder, as a metastatic malignancy, and with increasing incidence, as a primary tumor in AIDS patients. A series of hepatic leiomyosarcomas diagnosed by FNA biopsy, includi...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.2840110403
更新日期:1994-12-01 00:00:00
abstract:BACKGROUND:Vaginal fine-needle aspiration (FNA) is infrequently performed to assess palpable lesions. We perform the first multi-institutional study to evaluate this procedure. METHODS:We retrospectively reviewed vaginal FNAs performed at two institutions for the past 27 years. Clinical, cytological and histological d...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.23504
更新日期:2016-08-01 00:00:00
abstract::Histoplasmosis not uncommonly causes systemic infection, particularly in immunocompromised patients. In systemic infection, the urinary tract is often involved, although the diagnosis of histoplasmosis in urine cytologic specimens has never been reported. Urinary tract histoplasmosis may present with gross hematuria, ...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.10049
更新日期:2002-04-01 00:00:00
abstract::Seven cases of endometrial mucinous metaplasia and five of well-differentiated mucinous adenocarcinoma of the endometrium were studied. Cytologic specimens were obtained by Isaacs endometrial sampler, avoiding endocervical contamination. The histologic diagnosis between the intermediate type of mucinous metaplasia and...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.2840050208
更新日期:1989-01-01 00:00:00