Mucinous metaplasia to neoplastic lesions in endometrial samples with cytohistologic correlation.

Abstract:

:Seven cases of endometrial mucinous metaplasia and five of well-differentiated mucinous adenocarcinoma of the endometrium were studied. Cytologic specimens were obtained by Isaacs endometrial sampler, avoiding endocervical contamination. The histologic diagnosis between the intermediate type of mucinous metaplasia and the well-differentiated mucinous adenocarcinoma posed no problems. DNA analyses of the histologic samples showed a euploid pattern in benign and intermediate types of metaplasia, while well-differentiated mucinous adenocarcinoma showed a hyperdiploid pattern. The cytologic diagnosis of benign mucinous metaplasia should be suggested in the presence of abundant mucinous cells in endometrial samples in the absence of nuclear abnormalities.

journal_name

Diagn Cytopathol

journal_title

Diagnostic cytopathology

authors

Galera-Davidson H,Fernandez A,Navarro J,Parrilla A,Salguero M,Rivera F

doi

10.1002/dc.2840050208

subject

Has Abstract

pub_date

1989-01-01 00:00:00

pages

150-3

issue

2

eissn

8755-1039

issn

1097-0339

journal_volume

5

pub_type

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