Linear drive birdcage coil for 23Na human head studies at 1.5 T.

abstract：:By quantification of brain metabolites, localized brain proton MRS can non-invasively provide biochemical information from distinct regions of the brain. Quantification of short-TE signals is usually based on a metabolite basis set. The basis set can be obtained by two approaches: (1) by measuring the signals of metab...

journal_title：NMR in biomedicine

authors： Cudalbu C,Cavassila S,Rabeson H,van Ormondt D,Graveron-Demilly D

更新日期：2008-07-01 00:00:00

abstract：:In vitro (1)H MRS of human bile has shown potential in the diagnosis of various hepatopancreatobiliary (HPB) diseases. Previously, in vivo (1)H MRS of human bile in gallbladder using a 1.5 T scanner demonstrated the possibility of quantification of choline-containing phospholipids (chol-PLs). However, other lipid comp...

journal_title：NMR in biomedicine

authors： Mohajeri S,Ijare OB,Bezabeh T,King SB,Thomas MA,Minuk G,Lipschitz J,Kirkpatrick I,Smith M,Smith IC

更新日期：2014-10-01 00:00:00

abstract：:In many studies, it has been demonstrated that (1)H MRSI of the human prostate has great potential to aid prostate cancer management, e.g. in the detection and localisation of cancer foci in the prostate or in the assessment of its aggressiveness. It is particularly powerful in combination with T2 -weighted MRI. Never...

journal_title：NMR in biomedicine

authors： Kobus T,Wright AJ,Scheenen TW,Heerschap A

更新日期：2014-01-01 00:00:00

abstract：:The aim of this study was to measure choline/creatine (Ch/Cr) levels through (1)H-MRS and apparent diffusion coefficient (ADC) values through diffusion-weighted MRI, and to correlate these values with the prognostic parameters of head and neck squamous cell carcinoma (HNSCC). The institutional review board approved th...

journal_title：NMR in biomedicine

authors： Razek AA,Nada N

更新日期：2016-04-01 00:00:00

abstract：:The relaxation properties of water and metabolites were measured in rat brain following the occlusion of the middle cerebral artery (MCA) with localized 1H MRS. The PRESS sequence was employed to select volumes of 39 microL in the ischemic and the contralateral hemisphere. T1 and T2 relaxation times and peak intensiti...

journal_title：NMR in biomedicine

authors： van der Toorn A,Dijkhuizen RM,Tulleken CA,Nicolay K

更新日期：1995-09-01 00:00:00

abstract：:The elimination of so-called background fields is an essential step in phase MRI and quantitative susceptibility mapping (QSM). Background fields, which are caused by sources outside the region of interest (ROI), are often one to two orders of magnitude stronger than tissue-related field variations from within the ROI...

journal_title：NMR in biomedicine

authors： Schweser F,Robinson SD,de Rochefort L,Li W,Bredies K

更新日期：2017-04-01 00:00:00

abstract：:In this study, mapping of ultrashort T2 and T2* of acutely isolated porcine menisci at B0 = 9.4 T was investigated. Maps of T2 were measured from a slice through the pars intermedia with a spin echo-prepared two-dimensional ultrashort-TE T2 mapping technique published previously. T2* mapping was performed by two-dimen...

journal_title：NMR in biomedicine

authors： Kirsch S,Kreinest M,Reisig G,Schwarz ML,Ströbel P,Schad LR

更新日期：2013-09-01 00:00:00

abstract：:MRI detects changes in blood-oxygenation-level dependent (BOLD) contrast in tumors caused by tumor oxygenating agents. These changes can be used to guide the design of improved tumor oxygenating treatments (TOXs). The conventional approach to detection of BOLD effects assumes that the water resonance is a single, homo...

journal_title：NMR in biomedicine

authors： Al-Hallaq HA,Fan X,Zamora M,River JN,Moulder JE,Karczmar GS

更新日期：2002-02-01 00:00:00

abstract：:One of the hallmarks of diffusion NMR and MRI is its ability to utilize restricted diffusion to probe compartments much smaller than the excited volume or the MRI voxel, respectively, and to extract microstructural information from them. Single-pulsed field gradient (s-PFG) MR methodologies have been employed with gre...

journal_title：NMR in biomedicine

authors： Shemesh N,Ozarslan E,Komlosh ME,Basser PJ,Cohen Y

更新日期：2010-08-01 00:00:00

abstract：:Phosphorus MRSI (31 P-MRSI) using a spiral-trajectory readout at 7 T was developed for high temporal resolution mapping of the mitochondrial capacity of exercising human skeletal muscle. The sensitivity and localization accuracy of the method was investigated in phantoms. In vivo performance was assessed in 12 volunte...

journal_title：NMR in biomedicine

authors： Valkovič L,Chmelík M,Meyerspeer M,Gagoski B,Rodgers CT,Krššák M,Andronesi OC,Trattnig S,Bogner W

更新日期：2016-12-01 00:00:00

abstract：:Quantitative magnetisation transfer imaging (qMTI) is an extension of conventional MT techniques and allows the measurement of parameters that reflect tissue ultrastructure through the properties of macromolecule-bound protons; these include the bound proton fraction and the relaxation times of free and bound proton p...

journal_title：NMR in biomedicine

authors： Tozer DJ,Rees JH,Benton CE,Waldman AD,Jäger HR,Tofts PS

更新日期：2011-06-01 00:00:00

abstract：:This paper describes the development of a novel technique for functional MRI of the human brain at 0.135 microL resolution for a whole brain section. In comparison with conventional studies at 3 mm isotropic resolution or 27 microL voxel size, the method yields an improvement by a factor of 200. To achieve optimum ima...

journal_title：NMR in biomedicine

authors： Voit D,Frahm J

更新日期：2005-12-01 00:00:00

abstract：:The goals of this study were to develop an acquisition protocol and the analysis tools for Meshcher-Garwood point-resolved spectroscopy (MEGA-PRESS) in mouse brain at 9.4 T, to allow the in vivo detection of γ-aminobutyric acid (GABA) and to examine whether isoflurane alters GABA levels in the thalamus during anesthes...

journal_title：NMR in biomedicine

authors： Guo J,Gang Z,Sun Y,Laine A,Small SA,Rothman DL

更新日期：2018-01-01 00:00:00

abstract：:(1) H-MRS is regularly applied to determine lipid content in ectopic tissue - mostly skeletal muscle and liver - to investigate physiological and/or pathologic conditions, e.g. insulin resistance. Technical developments also allow non-invasive in vivo assessment of cardiac lipids; however, basic data about methodologi...

journal_title：NMR in biomedicine

authors： Ith M,Stettler C,Xu J,Boesch C,Kreis R

更新日期：2014-11-01 00:00:00

abstract：:The goal of this study was to validate metabolite quantification at short TE, with particular focus on how to best account for the macromolecular signal contribution. A robust, short-TE PRESS protocol is presented, which allows reliable quantification, in vivo, of metabolite signals at 3 T in human brain. Water suppre...

journal_title：NMR in biomedicine

authors： Gottschalk M,Lamalle L,Segebarth C

更新日期：2008-06-01 00:00:00

abstract：:A method to extract shapes of bubble polyhedra from three-dimensional nuclear magnetic resonance image data of foam has been developed. The method consists of four steps: first, to compute series of maximum intensity projection images from the three-dimensional NMR image data of foam to visualize the network structure...

journal_title：NMR in biomedicine

authors： Kashiwagi K,Kose K

更新日期：1997-01-01 00:00:00

abstract：:Nonbiological total disc replacement is currently being used for the treatment of intervertebral disc (IVD) disease and injury, but these implants are prone to mechanical wear, tear and possible dislodgement. Recently, tissue-engineered total disc replacement (TE-TDR) has been investigated as a possible alternative to...

journal_title：NMR in biomedicine

authors： Bowles RD,Gebhard HH,Dyke JP,Ballon DJ,Tomasino A,Cunningham ME,Härtl R,Bonassar LJ

更新日期：2012-03-01 00:00:00

abstract：:We have developed a reliable, reproducible model of hypoxia in the gerbil. 1H and 31P NMR spectroscopy demonstrates that cerebral energy metabolism is very resistant to hypoxia. Cerebral blood flow (measured by hydrogen clearance) began to increase when the arterial oxygen tension (paO2) was reduced to 40-50 mm Hg, an...

journal_title：NMR in biomedicine

authors： Allen K,Busza AL,Crockard HA,Gadian DG

更新日期：1992-01-01 00:00:00

abstract：:Previous studies have demonstrated that using hyperpolarized [2-13 C]pyruvate as a contrast agent can reveal 13 C signals from metabolites associated with the tricarboxylic acid (TCA) cycle. However, the metabolites detectable from TCA cycle-mediated oxidation of [2-13 C]pyruvate are the result of several metabolic st...

journal_title：NMR in biomedicine

authors： Chen AP,Lau AZ,Gu YP,Schroeder MA,Barry J,Cunningham CH

更新日期：2018-01-01 00:00:00

abstract：:Central obesity is the hallmark of a number of non-inheritable disorders. The advent of imaging techniques such as MRI has allowed for a fast and accurate assessment of body fat content and distribution. However, image analysis continues to be one of the major obstacles to the use of MRI in large-scale studies. In thi...

journal_title：NMR in biomedicine

authors： Borga M,Thomas EL,Romu T,Rosander J,Fitzpatrick J,Dahlqvist Leinhard O,Bell JD

更新日期：2015-12-01 00:00:00

abstract：:In MR elastography, it is common to use an elastic model for the tissue's response in order to interpret the results properly. More complex models, such as viscoelastic, fractional viscoelastic, poroelastic, or poroviscoelastic ones, are also used. These models appear at first sight to be very different, but here it i...

journal_title：NMR in biomedicine

authors： Holm S

更新日期：2018-10-01 00:00:00

abstract：:A quantitative magnetization transfer (qMT) technique was employed to quantify the ratio of the sizes of the bound and free water proton pools in ex vivo mouse brains. The goal was to determine the pool size ratio sensitivity to myelin. Fixed brains from both shiverer mice and control littermates were imaged. The pool...

journal_title：NMR in biomedicine

authors： Ou X,Sun SW,Liang HF,Song SK,Gochberg DF

更新日期：2009-06-01 00:00:00

abstract：:Diffusion tensor imaging (DTI) provides an indirect measure of tissue structure on a microscopic scale. To date, DTI is the only imaging method that provides such information in vivo, and has proven to be a valuable tool in both research and clinical settings. In this study, we investigated the relationship between wh...

journal_title：NMR in biomedicine

authors： Choe AS,Stepniewska I,Colvin DC,Ding Z,Anderson AW

更新日期：2012-07-01 00:00:00

abstract：:Surface coil 13C nuclear magnetic resonance (NMR) spectroscopy was used to investigate the in vivo carbohydrate metabolism of rat C6 gliomas during and after infusion with [1-13C] glucose. In vivo 1H-decoupled 13C NMR spectra of the glioma following infusion with [1-13C]glucose revealed the direct production of [3-13C...

journal_title：NMR in biomedicine

authors： Ross BD,Higgins RJ,Boggan JE,Willis JA,Knittel B,Unger SW

更新日期：1988-02-01 00:00:00

abstract：:The application of diffusion tensor imaging (DTI) to the evaluation of developing brain remains an area of active investigation. This review focuses on the changes in DTI parameters which accompany both brain maturation and injury. The two primary pieces of information available from DTI studies-water apparent diffusi...

journal_title：NMR in biomedicine

authors： Neil J,Miller J,Mukherjee P,Hüppi PS

更新日期：2002-11-01 00:00:00

abstract：:During the measurement of hyperpolarized 129 Xe magnetic resonance imaging (MRI), the diffusion-weighted imaging (DWI) technique provides valuable information for the assessment of lung morphometry at the alveolar level, whereas the chemical shift saturation recovery (CSSR) technique can evaluate the gas exchange func...

journal_title：NMR in biomedicine

authors： Zhong J,Zhang H,Ruan W,Xie J,Li H,Deng H,Han Y,Sun X,Ye C,Zhou X

更新日期：2017-08-01 00:00:00

abstract：:Transceiver surface coil arrays improve transmit performance (B1/√kW) and B1 homogeneity for head imaging up to 9.4 T. To further improve reception performance and parallel imaging, the number of array elements must be increased with a corresponding decrease in their size. With a large number of small interacting ante...

journal_title：NMR in biomedicine

authors： Avdievich NI,Pan JW,Hetherington HP

更新日期：2013-11-01 00:00:00

abstract：:The purpose of this study was to investigate the reliability of 3D isotropic MRI and quantitative multi-parametric MRI characterization on an orthotopic pancreatic head tumor model in rats. 3D isotropic T2 -weighted MRI was performed as a routine for tumor longitudinal follow-up and volume estimation. Common bile duct...

journal_title：NMR in biomedicine

authors： Yin T,Peeters R,Feng Y,Liu Y,Yu J,Dymarkowski S,Himmelreich U,Oyen R,Ni Y

更新日期：2017-02-01 00:00:00

abstract：:Proton magnetic resonance spectroscopy (MRS) was employed to determine the concentrations of N-acetylaspartate (NAA), total creatine (tCr), choline-containing compounds (Cho), myo-inositol (Ins), glucose (Glc), and lactate (Lac) in rat brain before and after 10 days of oral supplementation of 2.6 g Cr-monohydrate per ...

journal_title：NMR in biomedicine

authors： Michaelis T,Wick M,Fujimori H,Matsumura A,Frahm J

更新日期：1999-08-01 00:00:00

abstract：:The aim of this study was to acquire high-quality in vivo (1) H spectra concurrently from two voxels at ultra-high field (7 T) without specialized hardware. To this end, an acquisition scheme was developed in which first-order shims and flip angles are dynamically updated to acquire spectra from both of the brain's mo...

journal_title：NMR in biomedicine

authors： Lemke C,Hess A,Clare S,Bachtiar V,Stagg C,Jezzard P,Emir U

更新日期：2015-07-01 00:00:00