Abstract：
BACKGROUND:Changes in white blood cell (WBC) counts and/or temperature could have important implications in patients on ventilators, but the frequency of these events is uncertain. METHODS:We reviewed the medical records from 281 ventilation episodes in our medical intensive care unit to determine patient characteristics and the indications for ventilation. We determined the number of days during each ventilation episode in which the temperature (<96.8°F, >100.4°F) or WBC count (<4000/µL, >12 000/µL) was out of the normal range. RESULTS:This study included 257 patients with a mean Acute Physiology and Chronic Health Evaluation 2 score of 13.5 ± 5.9 and a mean initial Pao2/Fio2 of 210 ± 110. The median number of ventilator days was 4 (interquartile range, 3-9). One hundred ninety-six of 275 eligible ventilator episodes (71.3%) had 1 or more temperature events, and 194 of 253 eligible ventilator episodes (76.7%) had 1 or more WBC events. Nineteen patients met the Center for Disease Control criteria for a ventilator-associated event (VAE). Twelve patients had an increased WBC count during the VAE period, and 11 had an increased temperature during this period. CONCLUSIONS:White blood cell counts and temperature events occur frequently in patients on ventilators and need evaluation but do not reliably identify patients with ventilator-associated complications.
journal_name
J Intensive Care Medjournal_title
Journal of intensive care medicineauthors
Edriss H,Whiting J,Nugent Kdoi
10.1177/0885066615605036subject
Has Abstractpub_date
2017-05-01 00:00:00pages
273-277issue
4eissn
0885-0666issn
1525-1489pii
0885066615605036journal_volume
32pub_type
杂志文章abstract：PURPOSE:Atrial fibrillation (AF) is common in the intensive care unit (ICU), notably in patients with septic shock for whom inflammation is an already identified risk factor. The aim of this study was to evaluate the effect of low-dose hydrocortisone on AF occurrence in patients with septic shock. METHODS:We performed...
journal_title：Journal of intensive care medicine
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更新日期：2019-03-01 00:00:00
abstract：:Periodic epileptiform discharges (PEDs) are frequently encountered during continuous electroencephalography monitoring in the intensive care unit. Their implications and management are variable and highly dependent on the clinical context. This article is intended for the nonneurologist intensivist, reviews basic term...
journal_title：Journal of intensive care medicine
pub_type： 杂志文章,评审
doi：10.1177/0885066613513411
更新日期：2015-10-01 00:00:00
abstract：:Hypercalcemia may be seen in a variety of clinical settings and often requires intensive management when serum calcium levels are dramatically elevated. All of the many etiologies of mild hypercalcemia can lead to severe hypercalcemia. Knowledge of the physiologic mechanisms involved in maintaining normocalcemia and b...
journal_title：Journal of intensive care medicine
pub_type： 杂志文章,评审
doi：10.1177/0885066613507530
更新日期：2015-07-01 00:00:00
abstract：:Heparin-induced thrombocytopenia requires immediate alternative anticoagulation to prevent or treat thromboembolic complications. Argatroban was approved based on multiple-center studies from the 1990s, but subsequent changes in prevailing awareness, diagnostic testing and therapeutic strategies for heparin-induced th...
journal_title：Journal of intensive care medicine
pub_type： 杂志文章
doi：10.1177/0885066605284590
更新日期：2006-03-01 00:00:00
abstract：:The management of the critically ill patients with asthma can be rather challenging. Potentially devastating complications relating to this presentation include hypoxemia, worsening bronchospasm, pulmonary aspiration, tension pneumothorax, dynamic hyperinflation, hypotension, dysrhythmias, and seizures. In contrast to...
journal_title：Journal of intensive care medicine
pub_type： 杂志文章,评审
doi：10.1177/0885066617740079
更新日期：2018-09-01 00:00:00
abstract：INTRODUCTION:The use of transesophageal echocardiography (TEE) by intensivist physicians (IPs) and emergency physicians (EPs) in critically ill patients is increasing in the intensive care unit, emergency department, and prehospital environments. Coagulopathy and thrombocytopenia are common in critically ill patients. ...
journal_title：Journal of intensive care medicine
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更新日期：2021-01-01 00:00:00
abstract：:Hospital-acquired infections (HAIs) are common in intensive care unit (ICU) patients and are associated with increased morbidity and mortality. There has been an increasing effort to prevent HAIs, and infection control practices are paramount in avoiding these complications. In the last several years, numerous develop...
journal_title：Journal of intensive care medicine
pub_type： 杂志文章,评审
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更新日期：2014-11-01 00:00:00
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journal_title：Journal of intensive care medicine
pub_type： 杂志文章
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更新日期：2020-04-13 00:00:00
abstract：PURPOSE:We evaluated the effects of after-hours/nighttime patient transfers out of the ICU on patient outcomes, by performing a systematic review and meta-analysis (PROSPERO CRD 42017074082). DATA SOURCES:MEDLINE, PubMed, EMBASE, Google Scholar, CINAHL, and the Cochrane Library from 1987-November 2019. Conference abst...
journal_title：Journal of intensive care medicine
pub_type： 杂志文章
doi：10.1177/0885066620984410
更新日期：2020-12-28 00:00:00
abstract：OBJECTIVE:Fluid responsiveness is the ability to increase the cardiac output in response to a fluid challenge. Only about 50% of patients receiving fluid resuscitation for acute circulatory failure increase their stroke volume, but the other 50% may worsen their outcome. Therefore, predicting fluid responsiveness is ne...
journal_title：Journal of intensive care medicine
pub_type： 杂志文章,meta分析
doi：10.1177/0885066617752308
更新日期：2020-04-01 00:00:00
abstract：:Patients undergoing surgery for pituitary tumors represent a heterogeneous population each with unique clinical, biochemical, radiologic, pathologic, neurologic, and/or ophthalmologic considerations. The postoperative management of patients following pituitary surgery often occurs in the context of a dynamic state of ...
journal_title：Journal of intensive care medicine
pub_type： 杂志文章,评审
doi：10.1177/0885066605275247
更新日期：2005-05-01 00:00:00
abstract：INTRODUCTION:Emergence of multidrug-resistant (MDR) gram-negative (GN) pathogens and lack of novel antibiotics have increased the use of colistin, despite unknown optimal dosing. This study aimed to evaluate the safety and efficacy of a colistin loading dose, high-dose (LDHD) maintenance regimen in patients with MDR-GN...
journal_title：Journal of intensive care medicine
pub_type： 杂志文章
doi：10.1177/0885066616646551
更新日期：2017-09-01 00:00:00
abstract：:Left ventricular assist devices (LVADs) and total artificial hearts (TAHs) are surgically implanted as permanent treatment of unrecoverable heart failure. Both LVADs and TAHs are durable mechanical circulatory support (MCS) devices that can prolong patient survival but also alter end-of-life trajectory. The permissibi...
journal_title：Journal of intensive care medicine
pub_type： 杂志文章,评审
doi：10.1177/0885066611432415
更新日期：2014-01-01 00:00:00
abstract：BACKGROUND:Cognitive impairment after sepsis is an important clinical problem. Determinants of postseptic cognitive impairment are not well understood. We thus undertook a systems biology approach to exploring a possible role for apolipoprotein E (APOE) in postseptic cognitive impairment. DESIGN:Prospective, observati...
journal_title：Journal of intensive care medicine
pub_type： 杂志文章
doi：10.1177/0885066619897604
更新日期：2020-01-09 00:00:00
abstract：OBJECTIVE:When patients deteriorate after decannulation from extracorporeal membrane oxygenation (ECMO), a second run of extracorporeal support may be considered. However, repeat cannulation can be difficult and poor outcomes associated with multiple ECMO runs are a concern. The aim of this study was to evaluate outcom...
journal_title：Journal of intensive care medicine
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doi：10.1177/0885066620981903
更新日期：2020-12-22 00:00:00
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journal_title：Journal of intensive care medicine
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更新日期：2019-05-01 00:00:00
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journal_title：Journal of intensive care medicine
pub_type： 杂志文章
doi：10.1177/0885066618767619
更新日期：2020-06-01 00:00:00
abstract：:A review of adults with septic arthritis was undertaken to evaluate outcome of treatment and intensive care requirements in a community-based teaching hospital. During an 80-month period (1986-1992), 38 cases of septic arthritis were identified. Underlying joint disease was present in 84% of patients. Mean age was 68 ...
journal_title：Journal of intensive care medicine
pub_type： 杂志文章
doi：10.1177/088506669501000507
更新日期：1995-09-01 00:00:00
abstract：:Acute kidney injury (AKI) is common in critically ill patients and associated with increased morbidity and mortality. With the increased use of renal replacement therapy (RRT) for severe AKI, the optimal time for initiation of RRT has become one of the most probed and debated topic in the field of nephrology and criti...
journal_title：Journal of intensive care medicine
pub_type： 杂志文章,评审
doi：10.1177/0885066618774257
更新日期：2019-02-01 00:00:00
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journal_title：Journal of intensive care medicine
pub_type： 杂志文章,评审
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更新日期：2015-09-01 00:00:00
abstract：AIMS:To investigate the occurrence and etiology of fever at anytime during pediatric intensive care unit (PICU) admission, and to study its possible effects on clinical outcome in a heterogeneous population of critically ill children. METHODS:Retrospective, observational single center study, comprising 202 patients ag...
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更新日期：2009-09-01 00:00:00
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abstract：BACKGROUND:Consensus guidelines support the use of low-molecular-weight heparin for venous thromboembolism (VTE) prophylaxis in high-risk trauma patients but do not recommend a specific regimen. The current study compared the effectiveness and safety of enoxaparin 40 mg once-daily versus enoxaparin 30 mg twice-daily fo...
journal_title：Journal of intensive care medicine
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doi：10.1177/0885066610384462
更新日期：2011-03-01 00:00:00
abstract：OBJECTIVE:To evaluate the effect of high-flow nasal cannula oxygen (HFNO) therapy on hospital length of stay (LOS) and postoperative pulmonary complications (PPCs) in adult postoperative patients. DATA SOURCES:PubMed, Embase, the Cochrane Library, Web of Science of Studies, China National Knowledge Index, and Wan Fang...
journal_title：Journal of intensive care medicine
pub_type： 杂志文章
doi：10.1177/0885066618817718
更新日期：2020-10-01 00:00:00
abstract：BACKGROUND:Sepsis and sepsis-associated encephalopathy (SAE) are common intensive care unit (ICU) diseases; the morbidity and mortality are high. The present study analyzed the sensitivity of different diagnostic criteria of sepsis 1.0 and 3.0, epidemiological characteristics of sepsis and SAE, and explored its risk fa...
journal_title：Journal of intensive care medicine
pub_type： 杂志文章
doi：10.1177/0885066617719750
更新日期：2019-11-01 00:00:00
abstract：PURPOSE:Etomidate causes adrenal insufficiency. Yet in critically ill patients, it is controversial whether it increases mortality rates above that of comparator anesthetic induction agents. We postulated that etomidate would increase relative mortality rates correspondingly to the severity of illness as defined by SAP...
journal_title：Journal of intensive care medicine
pub_type： 杂志文章
doi：10.1177/0885066620957596
更新日期：2020-09-10 00:00:00
abstract：:Bronchopulmonary dysplasia is the most common morbidity among surviving premature infants. Injury to the developing lung is the result of the interaction between a susceptible host and a number of contributing factors such as mechanical ventilation and infection. The resulting persistent impairment of pulmonary functi...
journal_title：Journal of intensive care medicine
pub_type： 杂志文章,评审
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更新日期：2005-03-01 00:00:00
abstract：BACKGROUND:Diagnosing acute kidney injury (AKI) stage 3 in critically ill patients may help physicians in making treatment decisions. This diagnosis relies chiefly on urinary output and serum creatinine, which may be of limited value. This study aimed to explore the diagnostic performance of renal resistive index (RRI)...
journal_title：Journal of intensive care medicine
pub_type： 杂志文章
doi：10.1177/0885066619887333
更新日期：2021-01-01 00:00:00
abstract：:Substantial progress has been made to create innovative technology that can monitor the different physiological characteristics that precede the onset of secondary brain injury, with the ultimate goal of intervening prior to the onset of irreversible neurological damage. One of the goals of neurocritical care is to re...
journal_title：Journal of intensive care medicine
pub_type： 杂志文章,评审
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更新日期：2019-06-01 00:00:00
abstract：OBJECTIVE:The process of controlled donation after circulatory death (cDCD) is strongly connected with the process of withdrawal of life-sustaining therapy. In addition to impacting cDCD success, actions comprising withdrawal of life-sustaining therapy have implications for quality of palliative care. We examined pilot...
journal_title：Journal of intensive care medicine
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更新日期：2016-05-01 00:00:00
