Multimodality Monitoring in Neurocritical Care: Decision-Making Utilizing Direct And Indirect Surrogate Markers.

Abstract:

:Substantial progress has been made to create innovative technology that can monitor the different physiological characteristics that precede the onset of secondary brain injury, with the ultimate goal of intervening prior to the onset of irreversible neurological damage. One of the goals of neurocritical care is to recognize and preemptively manage secondary neurological injury by analyzing physiologic markers of ischemia and brain injury prior to the development of irreversible damage. This is helpful in a multitude of neurological conditions, whereby secondary neurological injury could present including but not limited to traumatic intracranial hemorrhage and, specifically, subarachnoid hemorrhage, which has the potential of progressing to delayed cerebral ischemia and monitoring postneurosurgical interventions. In this study, we examine the utilization of direct and indirect surrogate physiologic markers of ongoing neurologic injury, including intracranial pressure, cerebral blood flow, and brain metabolism.

journal_name

J Intensive Care Med

authors

Al-Mufti F,Lander M,Smith B,Morris NA,Nuoman R,Gupta R,Lissauer ME,Gupta G,Lee K

doi

10.1177/0885066618788022

subject

Has Abstract

pub_date

2019-06-01 00:00:00

pages

449-463

issue

6

eissn

0885-0666

issn

1525-1489

journal_volume

34

pub_type

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