Levosimendan for low cardiac output: a pediatric experience.

Abstract:

:This was a retrospective observational study in a pediatric intensive care unit, in which 19 patients received levosimendan. There were no adverse events attributable to levosimendan and no instances where the clinical condition worsened after administration. Arterial lactate levels decreased significantly following levosimendan administration during cardiopulmonary bypass for anticipated low cardiac output. In those with established low cardiac output, trends toward improved hemodynamics were seen, with heart rate reduction, an increase in mean blood pressure, a reduction in arterial lactate, and reduced conventional inotrope use. Levosimendan was safely used in a small number of pediatric patients with established low cardiac output state who demonstrated improved hemodynamics and tissue perfusion, with a tendency to reduced conventional inotrope usage, and this warrants its evaluation as an inotrope in the pediatric population.

journal_name

J Intensive Care Med

authors

Egan JR,Clarke AJ,Williams S,Cole AD,Ayer J,Jacobe S,Chard RB,Winlaw DS

doi

10.1177/0885066606287039

subject

Has Abstract

pub_date

2006-05-01 00:00:00

pages

183-7

issue

3

eissn

0885-0666

issn

1525-1489

pii

21/3/183

journal_volume

21

pub_type

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