Abstract:
PURPOSE:Conflicting data exists on the pharmacologic management of intensive care unit (ICU) delirium. This review appraises the current evidence of pharmacologic management of ICU delirium. MATERIALS AND METHODS:A systematic literature search of MEDLINE and Embase was conducted to answer the population, intervention, comparison, and outcome (PICO) question of: "Does the use of a pharmacologic agent compared to standard of care or placebo improve ICU delirium in a critically ill patient population?" RESULTS:After application of the PICO question and the inclusion and exclusion criteria, 13 articles were included. Of these articles, 7 were prospective randomized controlled trials, 1 was a prospective nonrandomized controlled trial, and 5 were retrospective investigations. The included articles differed in the agents evaluated, primary outcome, and method of identifying delirium. CONCLUSION:The variability of outcomes illustrates the need for a large-scale investigation to further evaluate the role of pharmacologic management of ICU delirium.
journal_name
J Intensive Care Medjournal_title
Journal of intensive care medicineauthors
Korenoski A,Li A,Kane-Gill SL,Seybert AL,Smithburger PLdoi
10.1177/0885066618805965subject
Has Abstractpub_date
2020-02-01 00:00:00pages
107-117issue
2eissn
0885-0666issn
1525-1489journal_volume
35pub_type
杂志文章abstract:BACKGROUND::The diagnosis of sepsis is challenging in the absence of a gold standard test. Recent studies have explored the role of neutrophil and monocyte volume, conductivity, and scatter (VCS), derived from automated hematology analyzers, in diagnosing sepsis. We assessed the diagnostic accuracy of VCS parameters in...
journal_title:Journal of intensive care medicine
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journal_title:Journal of intensive care medicine
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journal_title:Journal of intensive care medicine
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更新日期:2018-04-01 00:00:00
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更新日期:1995-09-01 00:00:00
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journal_title:Journal of intensive care medicine
pub_type: 杂志文章
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更新日期:2020-11-01 00:00:00
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journal_title:Journal of intensive care medicine
pub_type: 杂志文章,评审
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更新日期:1991-03-01 00:00:00
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更新日期:2009-09-01 00:00:00
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更新日期:2016-05-01 00:00:00