Abstract：
AIMS:To investigate the occurrence and etiology of fever at anytime during pediatric intensive care unit (PICU) admission, and to study its possible effects on clinical outcome in a heterogeneous population of critically ill children. METHODS:Retrospective, observational single center study, comprising 202 patients aged 0 to 18 years, admitted during a 6-month period between January and June 2004. Demographic and clinical data were collected. Fever was defined by a core temperature >or=38.3 degrees C. Outcomes of interest were duration of mechanical ventilation (MV) and PICU stay. Statistical analyses were done using nonparametric univariate analysis and multivariate Cox's regression analysis. RESULTS:Fever during PICU stay occurred in 82 of 202 children (40.6%). Demographic, clinical, and laboratory data of febrile patients were compared to data of nonfebrile patients. In 76 of the febrile patients (92.7%), fever occurred in the first 48 hours of admission and was associated with primary diagnosis in all cases. Six patients developed fever after 48 hours of admission and 8 patients developed a new febrile period after 48 nonfebrile hours. At least 50% of the late-onset fever was caused by cultured proven nosocomial infections, in the other cases a nosocomial infection was suspected. Fever after 48 hours of PICU admission or a secondary episode of fever was independently associated with prolonged length of ventilatory support and prolonged length of PICU stay. CONCLUSIONS:Fever in critically ill children occurs frequently during PICU stay. Fever after 48 hours of admission or new episodes of fever after 48 nonfebrile hours were mainly caused by nosocomial infections and was independently associated with prolonged length of ventilatory support and PICU stay.
journal_name
J Intensive Care Medjournal_title
Journal of intensive care medicineauthors
Gordijn MS,Plötz FB,Kneyber MCdoi
10.1177/0885066609340631subject
Has Abstractpub_date
2009-09-01 00:00:00pages
317-22issue
5eissn
0885-0666issn
1525-1489pii
0885066609340631journal_volume
24pub_type
杂志文章abstract：BACKGROUND:At this time, there are no studies evaluating the risk of delirium or coma with the use of ketamine in mechanically ventilated adult patients, compared to conventional therapies such as propofol or dexmedetomidine. OBJECTIVE:The objective of this study was to evaluate the number of days alive without deliri...
journal_title：Journal of intensive care medicine
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doi：10.1177/0885066618767619
更新日期：2020-06-01 00:00:00
abstract：:With the introduction of highly active antiretroviral therapy (HAART), HIV has become a chronic disease. As HIV-infected patients are aging, they are at increased risk for comorbid diseases. These non-AIDS related diseases account for a growing proportion of intensive care unit (ICU) admissions in HIV-infected patient...
journal_title：Journal of intensive care medicine
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abstract：BACKGROUND:Early fluid resuscitation is a key aspect in the successful management of critically ill patients, but the optimal goal for volume control after the acute stage of critical illness remains unclear. This study aimed to evaluate the prognostic value of bioimpedance spectrometry for fluid management in critical...
journal_title：Journal of intensive care medicine
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更新日期：2019-06-01 00:00:00
abstract：:Substantial progress has been made to create innovative technology that can monitor the different physiological characteristics that precede the onset of secondary brain injury, with the ultimate goal of intervening prior to the onset of irreversible neurological damage. One of the goals of neurocritical care is to re...
journal_title：Journal of intensive care medicine
pub_type： 杂志文章,评审
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更新日期：2019-06-01 00:00:00
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abstract：:The authors retrospectively review their experience with low immunoglobulin G (IgG) levels in a pediatric ICU population over a 12-month period. The total IgG level was below the normal for age in 14 of the 20 patients. The 14 patients with a low IgG level were younger and weighed less when compared with the 6 patient...
journal_title：Journal of intensive care medicine
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abstract：BACKGROUND:In the setting of the COVID pandemic, many patients falling ill with acute respiratory distress syndrome eventually require prone positioning for gas exchange. Traditionally, central venous catheters are inserted with patient in the supine or Trendelenburg position. However, when a patient cannot tolerate su...
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abstract：:Controlled donation after circulatory determination of death (cDCDD) concerns donation after withdrawal of life-sustaining therapy (W-LST). We examine the ethical issues raised by W-LST in the cDCDD context in the light of a review of cDCDD protocols and the ethical literature. Our analysis confirms that W-LST procedu...
journal_title：Journal of intensive care medicine
pub_type： 杂志文章,评审
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更新日期：2017-03-01 00:00:00
abstract：PURPOSE:Methods to optimize positive end-expiratory pressure (PEEP) in acute respiratory distress syndrome (ARDS) remain controversial despite decades of research. The pressure-volume curve (PVC), a graphical ventilator relationship, has been proposed for prescription of PEEP in ARDS. Whether the use of PVC's improves ...
journal_title：Journal of intensive care medicine
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更新日期：2014-11-01 00:00:00
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abstract：PURPOSE:The aim of this study was to check if serum lactate was independently associated with mortality among critically ill patients. MATERIALS AND METHODS:This was a single-center, retrospective cohort study. All adult patients (>18 years of age) who had at least 1 measurement of lactate within 24 hours of admission...
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abstract：BACKGROUND:There is variation in the treatment of patients with severe alcohol withdrawal and a need for effective protocols. The purpose of this study was to evaluate the implementation of a symptom-triggered benzodiazepine protocol using the 5-item Brief Alcohol Withdrawal Scale (BAWS) for treatment of alcohol withdr...
journal_title：Journal of intensive care medicine
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更新日期：2020-08-27 00:00:00
abstract：:Video laryngoscopy has demonstrated utility in airway management. For the present case series, we report the use of video laryngoscopy to evaluate the airway of critically ill, mechanically ventilated patients, as a means to reduce the risk of immediate postextubation stridor by assessing the degree of laryngeal edema...
journal_title：Journal of intensive care medicine
pub_type： 杂志文章
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更新日期：2013-01-01 00:00:00
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更新日期：2014-05-01 00:00:00
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journal_title：Journal of intensive care medicine
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更新日期：2020-09-28 00:00:00
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journal_title：Journal of intensive care medicine
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doi：10.1177/0885066607307528
更新日期：2007-11-01 00:00:00
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journal_title：Journal of intensive care medicine
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journal_title：Journal of intensive care medicine
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更新日期：1995-07-01 00:00:00
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journal_title：Journal of intensive care medicine
pub_type： 杂志文章,评审
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更新日期：2019-02-01 00:00:00
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journal_title：Journal of intensive care medicine
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更新日期：2020-10-29 00:00:00
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更新日期：2019-11-01 00:00:00
abstract：:A review of adults with septic arthritis was undertaken to evaluate outcome of treatment and intensive care requirements in a community-based teaching hospital. During an 80-month period (1986-1992), 38 cases of septic arthritis were identified. Underlying joint disease was present in 84% of patients. Mean age was 68 ...
journal_title：Journal of intensive care medicine
pub_type： 杂志文章
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更新日期：1995-09-01 00:00:00
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journal_title：Journal of intensive care medicine
pub_type： 杂志文章,meta分析
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更新日期：2020-05-01 00:00:00
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pub_type： 杂志文章,评审
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更新日期：2003-05-01 00:00:00
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abstract：PURPOSE:We evaluated the effects of after-hours/nighttime patient transfers out of the ICU on patient outcomes, by performing a systematic review and meta-analysis (PROSPERO CRD 42017074082). DATA SOURCES:MEDLINE, PubMed, EMBASE, Google Scholar, CINAHL, and the Cochrane Library from 1987-November 2019. Conference abst...
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更新日期：2020-12-28 00:00:00
