Cytokines and brain injury: invited review.

abstract：BACKGROUND::The diagnosis of sepsis is challenging in the absence of a gold standard test. Recent studies have explored the role of neutrophil and monocyte volume, conductivity, and scatter (VCS), derived from automated hematology analyzers, in diagnosing sepsis. We assessed the diagnostic accuracy of VCS parameters in...

journal_title：Journal of intensive care medicine

authors： Mammen J,Choudhuri J,Paul J,Sudarsan TI,Josephine T,Mahasampath G,Jeyaseelan V,Nair SC,Peter JV

更新日期：2018-12-01 00:00:00

abstract：:A systematic review of the literature was conducted to determine if the administration of methylene blue in humans improves hemodynamic status and/or outcome in patients with septic shock. Studies were identified from MEDLINE, EMBASE, and the Cochrane Central Register of Controlled Trials database. The review included...

journal_title：Journal of intensive care medicine

authors： Kwok ES,Howes D

更新日期：2006-11-01 00:00:00

abstract：INTRODUCTION:Although magnesium plays an important role in aerobic metabolism and magnesium deficiency is a common phenomenon in critical illness, the association between magnesium deficiency and lactic acidosis in the intensive care unit (ICU) has not been defined. METHODS:This was a retrospective, cross-sectional st...

journal_title：Journal of intensive care medicine

authors： Moskowitz A,Lee J,Donnino MW,Mark R,Celi LA,Danziger J

更新日期：2016-03-01 00:00:00

abstract：:This was a retrospective observational study in a pediatric intensive care unit, in which 19 patients received levosimendan. There were no adverse events attributable to levosimendan and no instances where the clinical condition worsened after administration. Arterial lactate levels decreased significantly following l...

journal_title：Journal of intensive care medicine

authors： Egan JR,Clarke AJ,Williams S,Cole AD,Ayer J,Jacobe S,Chard RB,Winlaw DS

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND:Poor communication among health-care providers is cited as the most common cause of sentinel events involving patients. Patient care in the critical care setting is incredibly complex. A consistent care plan is necessary between day/night shift teams and among bedside intensive care unit (ICU) nurses, consul...

journal_title：Journal of intensive care medicine

authors： Wessman BT,Sona C,Schallom M

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:There is variation in the treatment of patients with severe alcohol withdrawal and a need for effective protocols. The purpose of this study was to evaluate the implementation of a symptom-triggered benzodiazepine protocol using the 5-item Brief Alcohol Withdrawal Scale (BAWS) for treatment of alcohol withdr...

journal_title：Journal of intensive care medicine

authors： Rastegar DA,Jarrell AS,Chen ES

更新日期：2020-08-27 00:00:00

abstract：:Bladder pressure measurement through a foley catheter is the current standard in monitoring for intraabdominal hypertension (IAH) and abdominal compartment syndrome (ACS). Accurate pressure transduction requires a continuous fluid column with a small volume of transducing medium at the tip of the catheter. Infusing ex...

journal_title：Journal of intensive care medicine

authors： Kimball EJ,Baraghoshi GK,Mone MC,Hansen HJ,Adams DM,Alder SC,Jackson P,Cannon P,Horn J,Wolfe TR

更新日期：2009-07-01 00:00:00

abstract：:Early predictors of prognosis in comatose patients post cardiac arrest help inform decisions surrounding continuation or withdrawal of treatment and provide a framework on which to better inform relatives of the likely outcome. Markers defined prior to the widespread use of therapeutic hypothermia post arrest may no l...

journal_title：Journal of intensive care medicine

authors： Bigham S,Bigham C,Martin D

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:At this time, there are no studies evaluating the risk of delirium or coma with the use of ketamine in mechanically ventilated adult patients, compared to conventional therapies such as propofol or dexmedetomidine. OBJECTIVE:The objective of this study was to evaluate the number of days alive without deliri...

journal_title：Journal of intensive care medicine

authors： Shurtleff V,Radosevich JJ,Patanwala AE

更新日期：2020-06-01 00:00:00

abstract：RATIONALE:The feasibility and clinical outcomes of conservative fluid management after sepsis resuscitation remain unknown. OBJECTIVES:To evaluate the effect of a conservative fluid management protocol on fluid balance and intensive care unit (ICU)-free days among patients with sepsis. METHODS:In a single-center phas...

journal_title：Journal of intensive care medicine

authors： Semler MW,Janz DR,Casey JD,Self WH,Rice TW

更新日期：2020-12-01 00:00:00

abstract：OBJECTIVE:Fluid responsiveness is the ability to increase the cardiac output in response to a fluid challenge. Only about 50% of patients receiving fluid resuscitation for acute circulatory failure increase their stroke volume, but the other 50% may worsen their outcome. Therefore, predicting fluid responsiveness is ne...

journal_title：Journal of intensive care medicine

authors： Orso D,Paoli I,Piani T,Cilenti FL,Cristiani L,Guglielmo N

更新日期：2020-04-01 00:00:00

abstract：:Although the number of available donor hearts severely limits the epidemiologic impact of heart transplantation on patients with heart failure, patients with end-stage heart failure unresponsive to medical management currently have no other viable alternatives. Destination therapy with a ventricular assist device is t...

journal_title：Journal of intensive care medicine

authors： Poston RS,Griffith BP

更新日期：2004-01-01 00:00:00

abstract：:Respiratory complications before and after liver transplant are common, diverse, and potentially have a negative impact on patient outcomes. In this review, we discuss the most frequent respiratory conditions that patients may develop in the perioperative period. Their prevention and/or treatment may help to maximize ...

journal_title：Journal of intensive care medicine

authors： Cardoso FS,Karvellas CJ

更新日期：2019-05-01 00:00:00

abstract：OBJECTIVE:In the intensive care unit (ICU), prolonged inactivity is common, increasing patients' risk for adverse outcomes, including ICU-acquired weakness. Hence, interventions to minimize inactivity are gaining popularity, highlighting actigraphy, a measure of activity involving a wristwatch-like accelerometer, as a ...

journal_title：Journal of intensive care medicine

authors： Schwab KE,To AQ,Chang J,Ronish B,Needham DM,Martin JL,Kamdar BB

更新日期：2020-11-01 00:00:00

abstract：INTRODUCTION:The invasive nature and potential complications associated with pulmonary artery (PA) catheters (PACs) have prompted the pursuit of less invasive monitoring options. Before implementing new hemodynamic monitoring technologies, it is important to determine the interchangeability of these modalities. This st...

journal_title：Journal of intensive care medicine

authors： Eiferman DS,Davido HT,Howard JM,Gerckens J,Evans DC,Cook CH,Stawicki SP

更新日期：2016-02-01 00:00:00

abstract：INTRODUCTION:Cancer is associated with significant health-care expenditure, but few studies have examined the cost of patients with cancer in the intensive care unit (ICU). We aimed to describe the costs and outcomes of patients admitted to the ICU with cancer. METHODS:We conducted a retrospective cohort study of pati...

journal_title：Journal of intensive care medicine

authors： Zheng B,Reardon PM,Fernando SM,Webber C,Thavorn K,Thompson LH,Tanuseputro P,Munshi L,Kyeremanteng K

更新日期：2021-02-01 00:00:00

abstract：:The treatment of sepsis is an ongoing challenge for clinicians; despite the wide choice of effective antibiotics to treat infection, sepsis remains the leading cause of morbidity and mortality for patients admitted to an intensive care unit. Dysregulation of the immune response is now recognized to be a key factor in ...

journal_title：Journal of intensive care medicine

authors： Panagiotou A,Gaiao S,Cruz DN

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Pharmacogenomic (PGx) testing has the potential to provide information on specific drug-metabolizing enzymes that may lead to an absence, reduction, or increase in medication effect in patients. There is a paucity of prospective studies examining PGx testing in the intensive care unit (ICU) setting. RESEARC...

journal_title：Journal of intensive care medicine

authors： Peterson PE,Nicholson WT,Moyer AM,Arendt CJ,Smischney NJ,Seelhammer TG,Krecke CA,Haney RM,Yaw EJ,Chlan LL

更新日期：2020-07-31 00:00:00

abstract：BACKGROUND:Early fluid resuscitation is a key aspect in the successful management of critically ill patients, but the optimal goal for volume control after the acute stage of critical illness remains unclear. This study aimed to evaluate the prognostic value of bioimpedance spectrometry for fluid management in critical...

journal_title：Journal of intensive care medicine

authors： Yang SF,Tseng CM,Liu IF,Tsai SH,Kuo WS,Tsao TP

更新日期：2019-06-01 00:00:00

abstract：:A 70-year-old woman was admitted to the intensive care unit with refractory nonconvulsive status epilepticus. Extensive evaluation including neuroimaging and cerebrospinal fluid examination was unrevealing. Brain biopsy revealed spongiosis, and prion disease was confirmed by immunostaining, providing the diagnosis of ...

journal_title：Journal of intensive care medicine

authors： Shapiro JM,Shujaat A,Wang J,Chen X

更新日期：2004-11-01 00:00:00

abstract：OBJECTIVE:To examine racial and ethnic differences in the utilization of 3 interventions (tracheostomy placement, gastrostomy tube placement, and hospice utilization) among patients with severe acute brain injury (SABI). DESIGN:Retrospective cohort study. SETTING:Data from the National Inpatient Sample, from 2002 to ...

journal_title：Journal of intensive care medicine

authors： Jones RC,Creutzfeldt CJ,Cox CE,Haines KL,Hough CL,Vavilala MS,Williamson T,Hernandez A,Raghunathan K,Bartz R,Fuller M,Krishnamoorthy V

更新日期：2020-09-10 00:00:00

abstract：:Acute diverticulitis is a frequent and important diagnosis in gastrointestinal disease, most commonly involving the colon. It is estimated that approximately 15% to 30% of patients with diverticulosis develop symptomatic diverticulitis at some point in the natural history of the condition, often requiring medical and/...

journal_title：Journal of intensive care medicine

authors： Lawrimore T,Rhea JT

更新日期：2004-07-01 00:00:00

abstract：:Video laryngoscopy has demonstrated utility in airway management. For the present case series, we report the use of video laryngoscopy to evaluate the airway of critically ill, mechanically ventilated patients, as a means to reduce the risk of immediate postextubation stridor by assessing the degree of laryngeal edema...

journal_title：Journal of intensive care medicine

authors： Newmark JL,Ahn YK,Adams MC,Bittner EA,Wilcox SR

更新日期：2013-01-01 00:00:00

abstract：:Despite an overall decline in the incidence of tuberculosis (TB), the percentage of cases representing miliary TB has remained stable. We report 2 cases of fatal miliary TB that remained unrecognized until autopsy, occurring within a 6-month period at 1 Detroit institution. These cases represent the wide range of pres...

journal_title：Journal of intensive care medicine

authors： Bourbonnais JM,Sirithanakul K,Guzman JA

更新日期：2005-11-01 00:00:00

abstract：:The objective of this retrospective study was to determine the optimal initial antibiotic regimen for hospital-acquired pneumonia using the frequency and sensitivity of Gram negative microorganisms found in sputum cultures. An antibiogram was constructed and compared with the hospital intensive care unit (ICU) antibio...

journal_title：Journal of intensive care medicine

authors： Green DL

更新日期：2005-09-01 00:00:00

abstract：:Hyponatremia is the most frequently occurring electrolyte abnormality and can lead to life-threatening complications. This disorder may be present on admission to the intensive care setting or develop during hospitalization as a result of treatment or multiple comorbidities. Patients with acute hyponatremia or symptom...

journal_title：Journal of intensive care medicine

authors： Buffington MA,Abreo K

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:Sepsis and sepsis-associated encephalopathy (SAE) are common intensive care unit (ICU) diseases; the morbidity and mortality are high. The present study analyzed the sensitivity of different diagnostic criteria of sepsis 1.0 and 3.0, epidemiological characteristics of sepsis and SAE, and explored its risk fa...

journal_title：Journal of intensive care medicine

authors： Feng Q,Ai YH,Gong H,Wu L,Ai ML,Deng SY,Huang L,Peng QY,Zhang LN

更新日期：2019-11-01 00:00:00

abstract：:Extracorporeal membrane oxygenation (ECMO) comprises a commonly used method of extracorporeal life support. It has proven efficacy and is an accepted modality of care for isolated respiratory or cardiopulmonary failure in neonatal and pediatric populations. In adults, there are conflicting studies regarding its benefi...

journal_title：Journal of intensive care medicine

authors： Allen S,Holena D,McCunn M,Kohl B,Sarani B

更新日期：2011-01-01 00:00:00

abstract：:The aim of the study was to describe our experience with bi-level positive airway pressure (BiPAP) ventilation in oncology children with acute respiratory failure, hospitalized in a single tertiary pediatric tertiary center. This was a retrospective cohort study of all pediatric oncology patients in our center admitte...

journal_title：Journal of intensive care medicine

authors： Schiller O,Schonfeld T,Yaniv I,Stein J,Kadmon G,Nahum E

更新日期：2009-11-01 00:00:00

abstract：:Venous thromboembolism (VTE) is a major health concern associated with significant morbidity and mortality. Critically ill patients are at an increased risk of VTE compared to general medical patients due to unique risk factors: prolonged immobilization, invasive lines and devices, certain medications, and acquired th...

journal_title：Journal of intensive care medicine

authors： Lewis TC,Cortes J,Altshuler D,Papadopoulos J

更新日期：2019-11-01 00:00:00